U.S. flag

An official website of the United States government

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Links from GEO Profiles

Items: 1 to 20 of 408

1.
Neuronal substance-P drives metastasis via an extracellular RNA/TLR7 axis
Veena Padmanaban, Isabel Keller, Ethan S. Seltzer, Benjamin N. Ostendorf, Zachary Kerner, Sohail F. Tavazoie
Nature. Author manuscript; available in PMC 2024 Dec 11.
Published in final edited form as: Nature. 2024 Sep; 633(8028): 207–215. Published online 2024 Aug 7. doi: 10.1038/s41586-024-07767-5
PMCID:
PMC11633843
AbstractArticlePDF–7.0M
2.
Deficiency of Tlr7 and Irf7 in mice increases the severity of COVID-19 through the reduced interferon production
Chenxiao Wang, Mst Shamima Khatun, Calder R. Ellsworth, Zheng Chen, Mohammad Islamuddin, Ana Karina Nisperuza Vidal, Mohammad Afaque Alam, Shumei Liu, Janet E. Mccombs, Nicholas J. Maness, Robert V. Blair, Jay K. Kolls, Xuebin Qin
Commun Biol. 2024; 7: 1162. Published online 2024 Sep 17. doi: 10.1038/s42003-024-06872-5
PMCID:
PMC11408513
AbstractArticlePDF–4.4M
3.
Rabies Virus Regulates Inflammatory Response in BV-2 Cells through Activation of Myd88 and NF-κB Signaling Pathways via TLR7
Yuan Xie, Yinglin Chi, Xiaoyan Tao, Pengcheng Yu, Qian Liu, Minghui Zhang, Nuo Yang, Shuqing Liu, Wuyang Zhu
Int J Mol Sci. 2024 Sep; 25(17): 9144. Published online 2024 Aug 23. doi: 10.3390/ijms25179144
PMCID:
PMC11395267
AbstractArticlePDF–22M
4.
NADPH oxidase in B cells and macrophages protects against murine lupus by regulation of TLR7
Rachael A. Gordon, Haylee A. Cosgrove, Anthony Marinov, Sebastien Gingras, Jeremy S. Tilstra, Allison M. Campbell, Sheldon I. Bastacky, Michael Kashgarian, Andras Perl, Kevin M. Nickerson, Mark J. Shlomchik
JCI Insight. 2024 Aug 22; 9(16): e178563. Published online 2024 Jul 23. doi: 10.1172/jci.insight.178563
PMCID:
PMC11343599
AbstractArticlePDF–5.3M
5.
From hit to vial: Precision discovery and development of an imidazopyrimidine TLR7/8 agonist adjuvant formulation
Dheeraj Soni, Francesco Borriello, David A. Scott, Frederic Feru, Maria DeLeon, Spencer E. Brightman, Wing Ki Cheng, Gandolina Melhem, Jennifer A. Smith, Juan C. Ramirez, Soumik Barman, Michael Cameron, Aisling Kelly, Kristina Walker, Etsuro Nanishi, Simon Daniel van Haren, Tony Phan, Yizhi Qi, Robert Kinsey, Michal M. Raczy, Al Ozonoff, Matthew A. Pettengill, Jeffery A. Hubbell, Christopher B. Fox, David J. Dowling, Ofer Levy
Sci Adv. 2024 Jul 5; 10(27): eadg3747. Published online 2024 Jul 3. doi: 10.1126/sciadv.adg3747
PMCID:
PMC11221515
AbstractArticlePDF–3.4M
6.
The Role of TLR7 and TLR9 in the Pathogenesis of Systemic Sclerosis
Chenyang Wang, Kyosuke Oishi, Tadahiro Kobayashi, Ko Fujii, Motoki Horii, Natsumi Fushida, Tasuku Kitano, Shintaro Maeda, Yuichi Ikawa, Akito Komuro, Yasuhito Hamaguchi, Takashi Matsushita
Int J Mol Sci. 2024 Jun; 25(11): 6133. Published online 2024 Jun 1. doi: 10.3390/ijms25116133
PMCID:
PMC11172923
AbstractArticlePDF–4.2M
7.
TLR7-dependent eosinophil degranulation links psoriatic skin inflammation to small intestinal inflammatory changes in mice
Hee Joo Kim, Jinsun Jang, Kunhee Na, Eun-Hui Lee, Hyeon-Jung Gu, Yoon Hee Lim, Seul-A Joo, Seung Eun Baek, Joo-Young Roh, Han-Joo Maeng, Yun Hak Kim, Young-Jae Lee, Byung-Chul Oh, YunJae Jung
Exp Mol Med. 2024 May; 56(5): 1164–1177. Published online 2024 May 1. doi: 10.1038/s12276-024-01225-y
PMCID:
PMC11148187
AbstractArticlePDF–7.7M
8.
TLR7 activation of age-associated B cells mediates disease in a mouse model of primary Sjögren’s disease
Achamaporn Punnanitinont, Eileen M. Kasperek, Chengsong Zhu, Guan Yu, Jeffrey C. Miecznikowski, Jill M. Kramer
J Leukoc Biol. Author manuscript; available in PMC 2024 Apr 3.
Published in final edited form as: J Leukoc Biol. 2024 Feb 23; 115(3): 497–510. doi: 10.1093/jleuko/qiad135
PMCID:
PMC10990110
AbstractArticlePDF–1.4M
9.
MDSC-derived S100A8/9 contributes to lupus pathogenesis by promoting TLR7-mediated activation of macrophages and dendritic cells
Yonghong Yang, Xin Zhang, Lina Jing, Yucai Xiao, Yangzhe Gao, Yuxin Hu, Shujiao Jia, Guangxi Zhou, Huabao Xiong, Guanjun Dong
Cell Mol Life Sci. 2024 Dec; 81(1): 110. Published online 2024 Mar 1. doi: 10.1007/s00018-024-05155-w
PMCID:
PMC10907481
AbstractArticlePDF–10M
10.
Platelet TLR7 is essential for the formation of platelet–neutrophil complexes and low-density neutrophils in lupus nephritis
Sen Hee Tay, Olga Zharkova, Hui Yin Lee, Michelle Min Xuan Toh, Eshele Anak Libau, Teja Celhar, Sriram Narayanan, Patricia Jennifer Ahl, Wei Yee Ong, Craig Joseph, Jeffrey Chun Tatt Lim, Lingzhi Wang, Anis Larbi, Shen Liang, Aisha Lateef, Shizuo Akira, Lieng Hsi Ling, Thomas Paulraj Thamboo, Joe Poh Seng Yeong, Bernett Teck Kwong Lee, Steven W Edwards, Helen L Wright, Paul Anthony MacAry, John E Connolly, Anna-Marie Fairhurst
Rheumatology (Oxford) 2024 Feb; 63(2): 551–562. Published online 2023 Jun 21. doi: 10.1093/rheumatology/kead296
PMCID:
PMC10836995
AbstractArticlePDF–1.3M
11.
Gender Control of Mouse Embryos by Activation of TLR7/8 on X Sperm via Ligands dsRNA-40 and dsRNA-DR
Yunfei Hou, Jingfeng Peng, Linjun Hong, Zhenfang Wu, Enqin Zheng, Zicong Li
Molecules. 2024 Jan; 29(1): 262. Published online 2024 Jan 4. doi: 10.3390/molecules29010262
PMCID:
PMC10780660
AbstractArticlePDF–3.3M
12.
Multimodal control of dendritic cell functions by nociceptors
Pavel Hanč, Rodrigo J. Gonzalez, Irina B. Mazo, Yidi Wang, Talley Lambert, Gloria Ortiz, Evan W. Miller, Ulrich H. von Andrian
Science. Author manuscript; available in PMC 2023 Nov 13.
Published in final edited form as: Science. 2023 Mar 31; 379(6639): eabm5658. Published online 2023 Mar 31. doi: 10.1126/science.abm5658
PMCID:
PMC10642951
AbstractArticlePDF–2.7M
13.
LDL delivery of microbial small RNAs drives atherosclerosis through macrophage TLR8
Ryan M. Allen, Danielle L. Michell, Ashley B. Cavnar, Wanying Zhu, Neil Makhijani, Danielle M. Contreras, Chase A. Raby, Elizabeth M. Semler, Carlisle DeJulius, Mark Castleberry, Youmin Zhang, Marisol Ramirez-Solano, Shilin Zhao, Craig Duvall, Amanda C. Doran, Quanhu Sheng, MacRae F. Linton, Kasey C. Vickers
Nat Cell Biol. Author manuscript; available in PMC 2023 Oct 27.
Published in final edited form as: Nat Cell Biol. 2022 Dec; 24(12): 1701–1713. Published online 2022 Dec 6. doi: 10.1038/s41556-022-01030-7
PMCID:
PMC10609361
AbstractArticlePDF–7.4M
14.
TLR7 promotes chronic airway disease in RSV-infected mice
Mark A. Miles, Stella Liong, Felicia Liong, Madison Coward-Smith, Gemma S. Trollope, Osezua Oseghale, Jonathan R. Erlich, Robert D. Brooks, Jessica M. Logan, Shane Hickey, Hao Wang, Steven Bozinovski, John J. O’Leary, Doug A. Brooks, Stavros Selemidis
Front Immunol. 2023; 14: 1240552. Published online 2023 Sep 14. doi: 10.3389/fimmu.2023.1240552
PMCID:
PMC10545951
AbstractArticlePDF–22M
15.
B cell–intrinsic TLR7 expression drives severe lupus in TLR9-deficient mice
Haylee A. Cosgrove, Sebastien Gingras, Minjung Kim, Sheldon Bastacky, Jeremy S. Tilstra, Mark J. Shlomchik
JCI Insight. 2023 Aug 22; 8(16): e172219. Published online 2023 Aug 22. doi: 10.1172/jci.insight.172219
PMCID:
PMC10543715
AbstractArticlePDF–1.2M
16.
TLR7 promotes skin inflammation via activating NFκB-mTORC1 axis in rosacea
Yaqun Huang, Da Liu, Mengting Chen, San Xu, Qinqin Peng, Yan Zhu, Juan Long, Tangxiele Liu, Zhili Deng, Hongfu Xie, Ji Li, Fangfen Liu, Wenqin Xiao
PeerJ. 2023; 11: e15976. Published online 2023 Sep 26. doi: 10.7717/peerj.15976
PMCID:
PMC10540772
AbstractArticlePDF–11M
17.
EGF Receptor-dependent TLR7 Signaling in Macrophages Promotes Glomerular Injury in Crescentic Glomerulonephritis
Narihito Tatsumoto, Suguru Saito, Ian R. Rifkin, Ramon G. Bonegio, Daniel N. Leal, Ganes C. Sen, Moshe Arditi, Michifumi Yamashita
Lab Invest. Author manuscript; available in PMC 2023 Sep 27.
Published in final edited form as: Lab Invest. 2023 Sep; 103(9): 100190. Published online 2023 Jun 1. doi: 10.1016/j.labinv.2023.100190
PMCID:
PMC10527264
AbstractArticlePDF–2.4M
18.
CD8 T Cell‐Derived Exosomal miR‐186‐5p Elicits Renal Inflammation via Activating Tubular TLR7/8 Signal Axis
Xiaodong Xu, Shuang Qu, Changming Zhang, Mingchao Zhang, Weisong Qin, Guisheng Ren, Hao Bao, Limin Li, Ke Zen, Zhihong Liu
Adv Sci (Weinh) 2023 Sep; 10(25): 2301492. Published online 2023 Jul 3. doi: 10.1002/advs.202301492
PMCID:
PMC10477851
AbstractArticlePDF–5.2M
19.
TLR7 activation at epithelial barriers promotes emergency myelopoiesis and lung antiviral immunity
William D Jackson, Chiara Giacomassi, Sophie Ward, Amber Owen, Tiago C Luis, Sarah Spear, Kevin J Woollard, Cecilia Johansson, Jessica Strid, Marina Botto
eLife. 2023; 12: e85647. Published online 2023 Aug 11. doi: 10.7554/eLife.85647
PMCID:
PMC10465127
AbstractArticlePDF–5.0M
20.
TLR7 activation by miR-21 promotes renal fibrosis by activating the pro-inflammatory signaling pathway in tubule epithelial cells
Jeongwon Kim, Sugyeong Ha, Minjung Son, Doyeon Kim, Mi-Jeong Kim, Bumseok Kim, Donghwan Kim, Hae Young Chung, Ki Wung Chung
Cell Commun Signal. 2023; 21: 215. Published online 2023 Aug 18. doi: 10.1186/s12964-023-01234-w
PMCID:
PMC10439664
AbstractArticlePDF–18M

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Filter your results:

Find related data

Recent activity

You are here: NCBI > Literature > PubMed Central (PMC)
Support Center