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Select item 111155131.

Identification of an emerin–β-catenin complex in the heart important for intercalated disc architecture and β-catenin localisation

Matthew A. Wheeler, Alice Warley, Roland G. Roberts, Elisabeth Ehler, Juliet A. Ellis

Cell Mol Life Sci. 2010 Mar; 67(5): 781–796. Published online 2009 Dec 9. doi: 10.1007/s00018-009-0219-8

PMCID:: PMC11115513

Abstract Article PDF–907K

Select item 110786442.

Nesprin-2 is a novel scaffold protein for telethonin and FHL-2 in the cardiomyocyte sarcomere

Chen Li, Derek T. Warren, Can Zhou, Shanelle De Silva, Darren G.S. Wilson, Mitla Garcia-Maya, Matthew A. Wheeler, Peter Meinke, Greta Sawyer, Elisabeth Ehler, Manfred Wehnert, Li Rao, Qiuping Zhang, Catherine M. Shanahan

J Biol Chem. 2024 May; 300(5): 107254. Published online 2024 Apr 2. doi: 10.1016/j.jbc.2024.107254

PMCID:: PMC11078644

Abstract Article PDF–4.4M

Select item 109176603.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 107172404.

Emerin deficiency does not exacerbate cardiomyopathy in a murine model of Emery–Dreifuss muscular dystrophy caused by an LMNA gene mutation

Eiji Wada, Kohei Matsumoto, Nao Susumu, Megumi Kato, Yukiko K. Hayashi

J Physiol Sci. 2023; 73: 27. Published online 2023 Nov 8. doi: 10.1186/s12576-023-00886-0

PMCID:: PMC10717240

Abstract Article PDF–1.5M

Select item 104787535.

Lem2 is essential for cardiac development by maintaining nuclear integrity

Jacob A Ross, Nathaly Arcos-Villacis, Edmund Battey, Cornelis Boogerd, Constanza Avalos Orellana, Emilie Marhuenda, Pamela Swiatlowska, Didier Hodzic, Fabrice Prin, Tim Mohun, Norman Catibog, Olga Tapia, Larry Gerace, Thomas Iskratsch, Ajay M Shah, Matthew J Stroud

Cardiovasc Res. 2023 Aug; 119(11): 2074–2088. Published online 2023 Apr 17. doi: 10.1093/cvr/cvad061

PMCID:: PMC10478753

Abstract Article PDF–33M

Select item 101965756.

Quantitative Proteomic Analysis Reveals apoE4-Dependent Phosphorylation of the Actin-Regulating Protein VASP

Zeynep Cakir, Samuel J. Lord, Yuan Zhou, Gwendolyn M. Jang, Benjamin J. Polacco, Manon Eckhardt, David Jimenez-Morales, Billy W. Newton, Adam L. Orr, Jeffrey R. Johnson, Alexandre da Cruz, R. Dyche Mullins, Nevan J. Krogan, Robert W. Mahley, Danielle L. Swaney

Mol Cell Proteomics. 2023 May; 22(5): 100541. Published online 2023 Apr 4. doi: 10.1016/j.mcpro.2023.100541

PMCID:: PMC10196575

Abstract Article PDF–4.5M

Select item 94819337.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 79387708.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 78465579.

The nuclear envelope protein Net39 is essential for muscle nuclear integrity and chromatin organization

Andres Ramirez-Martinez, Yichi Zhang, Kenian Chen, Jiwoong Kim, Bercin K. Cenik, John R. McAnally, Chunyu Cai, John M. Shelton, Jian Huang, Ana Brennan, Bret M. Evers, Pradeep P. A. Mammen, Lin Xu, Rhonda Bassel-Duby, Ning Liu, Eric N. Olson

Nat Commun. 2021; 12: 690. Published online 2021 Jan 29. doi: 10.1038/s41467-021-20987-x

PMCID:: PMC7846557

Abstract Article PDF–2.9M

Select item 759022110.

Postnatal development of mice with combined genetic depletions of lamin A/C, emerin and lamina-associated polypeptide 1

Yuexia Wang, Ji-Yeon Shin, Koki Nakanishi, Shunichi Homma, Grace J Kim, Kurenai Tanji, Leroy C Joseph, John P Morrow, Colin L Stewart, Willian T Dauer, Howard J Worman

Hum Mol Genet. 2019 Aug 1; 28(15): 2486–2500. Published online 2019 Apr 22. doi: 10.1093/hmg/ddz082

PMCID:: PMC7590221

Abstract Article PDF–20M

Select item 745518911.

The NEMP family supports metazoan fertility and nuclear envelope stiffness

Yonit Tsatskis, Robyn Rosenfeld, Joel D. Pearson, Curtis Boswell, Yi Qu, Kyunga Kim, Lacramioara Fabian, Ariz Mohammad, Xian Wang, Michael I. Robson, Karen Krchma, Jun Wu, João Gonçalves, Didier Hodzic, Shu Wu, Daniel Potter, Laurence Pelletier, Wade H. Dunham, Anne-Claude Gingras, Yu Sun, Jin Meng, Dorothea Godt, Tim Schedl, Brian Ciruna, Kyunghee Choi, John R. B. Perry, Rod Bremner, Eric C. Schirmer, Julie A. Brill, Andrea Jurisicova, Helen McNeill

Sci Adv. 2020 Aug; 6(35): eabb4591. Published online 2020 Aug 28. doi: 10.1126/sciadv.abb4591

PMCID:: PMC7455189

Abstract Article PDF–3.4M

Select item 741599112.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 680296713.

Selective clearance of the inner nuclear membrane protein emerin by vesicular transport during ER stress

Abigail Buchwalter, Roberta Schulte, Hsiao Tsai, Juliana Capitanio, Martin Hetzer

eLife. 2019; 8: e49796. Published online 2019 Oct 10. doi: 10.7554/eLife.49796

PMCID:: PMC6802967

Abstract Article PDF–6.6M

Select item 670177014.

Deficiency of emerin contributes differently to the pathogenesis of skeletal and cardiac muscles in Lmna^H222P/H222P mutant mice

Eiji Wada, Megumi Kato, Kaori Yamashita, Hiroko Kokuba, Wen-Chen Liang, Gisèle Bonne, Yukiko K. Hayashi

PLoS One. 2019; 14(8): e0221512. Published online 2019 Aug 20. doi: 10.1371/journal.pone.0221512

PMCID:: PMC6701770

Abstract Article PDF–3.7M

Select item 651832815.

Substrate stiffness-dependent regulation of the SRF−Mkl1 co-activator complex requires the inner nuclear membrane protein Emerin

Margaret K. Willer, Christopher W. Carroll

J Cell Sci. 2017 Jul 1; 130(13): 2111–2118. Published online 2017 Jul 1. doi: 10.1242/jcs.197517

PMCID:: PMC6518328

Abstract Article

Select item 629804016.

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors

Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman

Cell. Author manuscript; available in PMC 2019 Dec 13.

Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025