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Items: 1 to 20 of 84

1.
Structural and Functional Adaptability of Sucrose and Lactose Permeases from Escherichia coli to the Membrane Lipid Composition
Heidi Vitrac, Venkata K. P. S. Mallampalli, Stavros Azinas, William Dowhan
Biochemistry. Author manuscript; available in PMC 2020 Sep 18.
Published in final edited form as: Biochemistry. 2020 May 19; 59(19): 1854–1868. Published online 2020 May 7. doi: 10.1021/acs.biochem.0c00174
PMCID:
PMC7500855
AbstractArticlePDF–2.6M
2.
Diversity in kinetics correlated with structure in nano body-stabilized LacY
Hemant Kumar, Janet Finer-Moore, Irina Smirnova, Vladimir Kasho, Els Pardon, Jan Steyaert, H. Ronald Kaback, Robert M. Stroud
PLoS One. 2020; 15(5): e0232846. Published online 2020 May 7. doi: 10.1371/journal.pone.0232846
PMCID:
PMC7205474
AbstractArticlePDF–2.1M
3.
Oversized galactosides as a probe for conformational dynamics in LacY
Irina Smirnova, Vladimir Kasho, Xiaoxu Jiang, Hong-Ming Chen, Stephen G. Withers, H. Ronald Kaback
Proc Natl Acad Sci U S A. 2018 Apr 17; 115(16): 4146–4151. Published online 2018 Mar 30. doi: 10.1073/pnas.1800706115
PMCID:
PMC5910868
AbstractArticlePDF–1.0M
4.
Role of Conserved Gly-Gly Pairs on the Periplasmic Side of LacY
Xiaoxu Jiang, Magnus Andersson, Bryan T. Chau, Larissa Y. Wong, Maria Katerina R. Villafuerte, H. Ronald Kaback
Biochemistry. Author manuscript; available in PMC 2017 Jun 2.
Published in final edited form as: Biochemistry. 2016 Aug 9; 55(31): 4326–4332. Published online 2016 Aug 1. doi: 10.1021/acs.biochem.6b00666
PMCID:
PMC5456280
AbstractArticlePDF–1.3M
5.
pKa of Glu325 in LacY
Natalia Grytsyk, Junichi Sugihara, H. Ronald Kaback, Petra Hellwig
Proc Natl Acad Sci U S A. 2017 Feb 14; 114(7): 1530–1535. Published online 2017 Feb 1. doi: 10.1073/pnas.1621431114
PMCID:
PMC5320973
AbstractArticlePDF–966K
6.
Crystal structure of a LacY–nanobody complex in a periplasmic-open conformation
Xin Jiang, Irina Smirnova, Vladimir Kasho, Jianping Wu, Kunio Hirata, Meng Ke, Els Pardon, Jan Steyaert, Nieng Yan, H. Ronald Kaback
Proc Natl Acad Sci U S A. 2016 Nov 1; 113(44): 12420–12425. Published online 2016 Oct 19. doi: 10.1073/pnas.1615414113
PMCID:
PMC5098631
AbstractArticlePDF–1.4M
7.
YidC assists the stepwise and stochastic folding of membrane proteins
Tetiana Serdiuk, Dhandayuthapani Balasubramaniam, Junichi Sugihara, Stefania A. Mari, H. Ronald Kaback, Daniel J. Müller
Nat Chem Biol. Author manuscript; available in PMC 2017 Mar 5.
Published in final edited form as: Nat Chem Biol. 2016 Nov; 12(11): 911–917. Published online 2016 Sep 5. doi: 10.1038/nchembio.2169
PMCID:
PMC5069129
AbstractArticlePDF–2.3M
8.
pH Regulation of Electrogenic Sugar/H+ Symport in MFS Sugar Permeases
Andre Bazzone, M. Gregor Madej, H. Ronald Kaback, Klaus Fendler
PLoS One. 2016; 11(5): e0156392. Published online 2016 May 26. doi: 10.1371/journal.pone.0156392
PMCID:
PMC4882079
AbstractArticlePDF–3.0M
9.
Conserved movement of TMS11 between occluded conformations of LacY and XylE of the Major Facilitator Superfamily suggests a similar hinge-like mechanism
Åke Västermark, Adelle Driker, Jiaqi Li, Milton H. Saier, Jr.
Proteins. Author manuscript; available in PMC 2016 Apr 1.
Published in final edited form as: Proteins. 2015 Apr; 83(4): 735–745. Published online 2015 Feb 7. doi: 10.1002/prot.24755
PMCID:
PMC4368487
AbstractArticlePDF–567K
10.
Outward-facing conformers of LacY stabilized by nanobodies
Irina Smirnova, Vladimir Kasho, Xiaoxu Jiang, Els Pardon, Jan Steyaert, H. Ronald Kaback
Proc Natl Acad Sci U S A. 2014 Dec 30; 111(52): 18548–18553. Published online 2014 Dec 15. doi: 10.1073/pnas.1422265112
PMCID:
PMC4284591
AbstractArticlePDF–1.0M
11.
Phosphatidylethanolamine and Monoglucosyldiacylglycerol Are Interchangeable in Supporting Topogenesis and Function of the Polytopic Membrane Protein Lactose Permease
Jun Xie, Mikhail Bogdanov, Philip Heacock, William Dowhan
J Biol Chem. Author manuscript; available in PMC 2014 Jul 5.
Published in final edited form as: J Biol Chem. 2006 Jul 14; 281(28): 19172–19178. Published online 2006 May 12. doi: 10.1074/jbc.M602565200
PMCID:
PMC4082682
AbstractArticlePDF–390K
12.
Real-time conformational changes in LacY
Irina Smirnova, Vladimir Kasho, H. Ronald Kaback
Proc Natl Acad Sci U S A. 2014 Jun 10; 111(23): 8440–8445. Published online 2014 May 28. doi: 10.1073/pnas.1408374111
PMCID:
PMC4060661
AbstractArticlePDF–1.2M
13.
Trp replacements for tightly interacting Gly–Gly pairs in LacY stabilize an outward-facing conformation
Irina Smirnova, Vladimir Kasho, Junichi Sugihara, H. Ronald Kaback
Proc Natl Acad Sci U S A. 2013 May 28; 110(22): 8876–8881. Published online 2013 May 13. doi: 10.1073/pnas.1306849110
PMCID:
PMC3670396
AbstractArticlePDF–1.0M
14.
Cardiolipin and the osmotic stress responses of bacteria
Tatyana Romantsov, Ziqiang Guan, Janet M. Wood
Biochim Biophys Acta. Author manuscript; available in PMC 2013 Apr 10.
Published in final edited form as: Biochim Biophys Acta. 2009 Oct; 1788(10): 2092–2100. Published online 2009 Jun 17. doi: 10.1016/j.bbamem.2009.06.010
PMCID:
PMC3622477
AbstractArticlePDF–2.2M
15.
Proper Fatty Acid Composition Rather than an Ionizable Lipid Amine Is Required for Full Transport Function of Lactose Permease from Escherichia coli
Heidi Vitrac, Mikhail Bogdanov, William Dowhan
J Biol Chem. 2013 Feb 22; 288(8): 5873–5885. Published online 2013 Jan 15. doi: 10.1074/jbc.M112.442988
PMCID:
PMC3581378
AbstractArticlePDF–1.6M
16.
Lipid-dependent Generation of Dual Topology for a Membrane Protein
Mikhail Bogdanov, William Dowhan
J Biol Chem. 2012 Nov 2; 287(45): 37939–37948. Published online 2012 Sep 11. doi: 10.1074/jbc.M112.404103
PMCID:
PMC3488065
AbstractArticlePDF–895K
17.
Evidence for an intermediate conformational state of LacY
Xiaoxu Jiang, Lan Guan, Yonggang Zhou, Wen-Xu Hong, Qinghai Zhang, H. Ronald Kaback
Proc Natl Acad Sci U S A. 2012 Mar 20; 109(12): E698-E704. Published online 2012 Feb 21. doi: 10.1073/pnas.1201107109
PMCID:
PMC3311394
AbstractArticlePDF–2.5M
18.
Sugar recognition by CscB and LacY
Junichi Sugihara, Irina Smirnova, Vladimir Kasho, H. Ronald Kaback
Biochemistry. Author manuscript; available in PMC 2012 Dec 27.
Published in final edited form as: Biochemistry. 2011 Dec 27; 50(51): 11009–11014. Published online 2011 Dec 1. doi: 10.1021/bi201592y
PMCID:
PMC3249425
AbstractArticlePDF–769K
19.
Lactose Permease and the Alternating Access Mechanism
Irina Smirnova, Vladimir Kasho, H. Ronald Kaback
Biochemistry. Author manuscript; available in PMC 2012 Nov 15.
Published in final edited form as: Biochemistry. 2011 Nov 15; 50(45): 9684–9693. Published online 2011 Oct 19. doi: 10.1021/bi2014294
PMCID:
PMC3210931
AbstractArticlePDF–4.6M
20.
An Early Event in the Transport Mechanism of LacY Protein: INTERACTION BETWEEN HELICES V AND I
Yonggang Zhou, M. Gregor Madej, Lan Guan, Yiling Nie, H. Ronald Kaback
J Biol Chem. 2011 Sep 2; 286(35): 30415–30422. Published online 2011 Jul 7. doi: 10.1074/jbc.M111.268433
PMCID:
PMC3162401
AbstractArticlePDF–1.4M

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