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Select item 110680121.

Drosophila TET acts with PRC1 to activate gene expression independently of its catalytic activity

Guerric Gilbert, Yoan Renaud, Camille Teste, Nadège Anglaret, Romane Bertrand, Sven Hoehn, Tomasz P. Jurkowski, Bernd Schuettengruber, Giacomo Cavalli, Lucas Waltzer, Laurence Vandel

Sci Adv. 2024 May 3; 10(18): eadn5861. Published online 2024 May 3. doi: 10.1126/sciadv.adn5861

PMCID:: PMC11068012

Abstract Article PDF–12M

Select item 110353722.

Tet controls axon guidance in early brain development through glutamatergic signaling

Hiep Tran, Le Le, Badri Nath Singh, Joseph Kramer, Ruth Steward

iScience. 2024 May 17; 27(5): 109634. Published online 2024 Apr 1. doi: 10.1016/j.isci.2024.109634

PMCID:: PMC11035372

Abstract Article PDF–3.6M

Select item 110215193.

Niche Tet maintains germline stem cells independently of dioxygenase activity

Renjun Tu, Zhaohua Ping, Jian Liu, Man Lung Tsoi, Xiaoqing Song, Wei Liu, Ting Xie

EMBO J. 2024 Apr; 43(8): 1570–1590. Published online 2024 Mar 18. doi: 10.1038/s44318-024-00074-9

PMCID:: PMC11021519

Abstract Article PDF–11M

Select item 109177974.

A single-cell atlas of Drosophila trachea reveals glycosylation-mediated Notch signaling in cell fate specification

Yue Li, Tianfeng Lu, Pengzhen Dong, Jian Chen, Qiang Zhao, Yuying Wang, Tianheng Xiao, Honggang Wu, Quanyi Zhao, Hai Huang

Nat Commun. 2024; 15: 2019. Published online 2024 Mar 6. doi: 10.1038/s41467-024-46455-w

PMCID:: PMC10917797

Abstract Article PDF–5.3M

Select item 108810075.

Tet-dependent 5-hydroxymethyl-Cytosine modification of mRNA regulates axon guidance genes in Drosophila

Badri Nath Singh, Hiep Tran, Joseph Kramer, Elmira Kirichenko, Neha Changela, Fei Wang, Yaping Feng, Dibyendu Kumar, Min Tu, Jie Lan, Martin Bizet, François Fuks, Ruth Steward

PLoS One. 2024; 19(2): e0293894. Published online 2024 Feb 21. doi: 10.1371/journal.pone.0293894

PMCID:: PMC10881007

Abstract Article PDF–3.3M

Select item 107352196.

Adenine methylation is very scarce in the Drosophila genome and not erased by the ten-eleven translocation dioxygenase

Manon Boulet, Guerric Gilbert, Yoan Renaud, Martina Schmidt-Dengler, Emilie Plantié, Romane Bertrand, Xinsheng Nan, Tomasz Jurkowski, Mark Helm, Laurence Vandel, Lucas Waltzer

eLife. 2023; 12: RP91655. Published online 2023 Dec 21. doi: 10.7554/eLife.91655

PMCID:: PMC10735219

Abstract Article PDF–1.1M

Select item 105738657.

N⁶-Methyladenine Progressively Accumulates in Mitochondrial DNA during Aging

Ádám Sturm, Himani Sharma, Ferenc Bodnár, Maryam Aslam, Tibor Kovács, Ákos Németh, Bernadette Hotzi, Viktor Billes, Tímea Sigmond, Kitti Tátrai, Balázs Egyed, Blanka Téglás-Huszár, Gitta Schlosser, Nikolaos Charmpilas, Christina Ploumi, András Perczel, Nektarios Tavernarakis, Tibor Vellai

Int J Mol Sci. 2023 Oct; 24(19): 14858. Published online 2023 Oct 3. doi: 10.3390/ijms241914858

PMCID:: PMC10573865

Abstract Article PDF–3.6M

Select item 101794618.

Genome-Wide Expression Analysis of Long Noncoding RNAs and Their Target Genes in Metafemale Drosophila

Xinyu Liu, Ran Yan, Haosheng Liu, Shuai Zhang, Ruixue Wang, Bowen Zhang, Lin Sun

Int J Mol Sci. 2023 May; 24(9): 8381. Published online 2023 May 6. doi: 10.3390/ijms24098381

PMCID:: PMC10179461

Abstract Article PDF–8.2M

Select item 100720679.

Phenotypic and transcriptomic impact of expressing mammalian TET2 in the Drosophila melanogaster model

Joy N. Ismail, Sarah Mantash, Mohammad Hallal, Nada Jabado, Pierre Khoueiry, Margret Shirinian

Epigenetics. 2023; 18(1): 2192375. Published online 2023 Mar 29. doi: 10.1080/15592294.2023.2192375

PMCID:: PMC10072067

Abstract Article PDF–8.4M

Select item 943675210.

Leishmania amazonensis sabotages host cell SUMOylation for intracellular survival

Kendi Okuda, Miriam Maria Silva Costa Franco, Ari Yasunaga, Ricardo Gazzinelli, Michel Rabinovitch, Sara Cherry, Neal Silverman

iScience. 2022 Sep 16; 25(9): 104909. Published online 2022 Aug 13. doi: 10.1016/j.isci.2022.104909

PMCID:: PMC9436752

Abstract Article PDF–3.3M

Select item 904547911.

Drosophila Tet Is Required for Maintaining Glial Homeostasis in Developing and Adult Fly Brains

Felice Frey, Jawdat Sandakly, Mirna Ghannam, Caren Doueiry, Fredrik Hugosson, Johannes Berlandi, Joy N. Ismail, Tenzin Gayden, Martin Hasselblatt, Nada Jabado, Margret Shirinian

eNeuro. 2022 Mar-Apr; 9(2): ENEURO.0418-21.2022. Prepublished online 2022 Apr 8. Published online 2022 Apr 22. doi: 10.1523/ENEURO.0418-21.2022

PMCID:: PMC9045479

Abstract Article PDF–7.2M

Select item 866983412.

Tumor–host interactions through the lens of Drosophila

David Bilder, Katy Ong, Tsai-Ching Hsi, Kavya Adiga, Jung Kim

Nat Rev Cancer. Author manuscript; available in PMC 2022 May 1.

Published in final edited form as: Nat Rev Cancer. 2021 Nov; 21(11): 687–700. Published online 2021 Aug 13. doi: 10.1038/s41568-021-00387-5

PMCID:: PMC8669834

Abstract Article PDF–385K

Select item 866448613.

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349

PMCID:: PMC8664486

Abstract Article PDF–3.1M

Select item 846561114.

Chromatin Organization and Function in Drosophila

Palmira Llorens-Giralt, Carlos Camilleri-Robles, Montserrat Corominas, Paula Climent-Cantó

Cells. 2021 Sep; 10(9): 2362. Published online 2021 Sep 8. doi: 10.3390/cells10092362

PMCID:: PMC8465611

Abstract Article PDF–1.2M

Select item 804227015.

Comprehensive Identification and Alternative Splicing of Microexons in Drosophila

Ting-Lin Pang, Zhan Ding, Shao-Bo Liang, Liang Li, Bei Zhang, Yu Zhang, Yu-Jie Fan, Yong-Zhen Xu

Front Genet. 2021; 12: 642602. Published online 2021 Mar 30. doi: 10.3389/fgene.2021.642602

PMCID:: PMC8042270

Abstract Article PDF–3.6M

Select item 780346316.

I-KCKT allows dissection-free RNA profiling of adult Drosophila intestinal progenitor cells

Kasun Buddika, Jingjing Xu, Ishara S. Ariyapala, Nicholas S. Sokol

Development. 2021 Jan 1; 148(1): dev196568. Published online 2021 Jan 7. doi: 10.1242/dev.196568

PMCID:: PMC7803463

Abstract Article

Select item 764864817.

A single-cell atlas and lineage analysis of the adult Drosophila ovary

Katja Rust, Lauren E. Byrnes, Kevin Shengyang Yu, Jason S. Park, Julie B. Sneddon, Aaron D. Tward, Todd G. Nystul

Nat Commun. 2020; 11: 5628. Published online 2020 Nov 6. doi: 10.1038/s41467-020-19361-0

Correction in:: Nat Commun. 2021; 12: 5951.

PMCID:: PMC7648648

Abstract Article PDF–6.1M

Select item 759563418.

Ten-eleven translocation proteins and their role beyond DNA demethylation – what we can learn from the fly

Joy N. Ismail, Mirna Ghannam, Amani Al Outa, Felice Frey, Margret Shirinian

Epigenetics. 2020; 15(11): 1139–1150. Published online 2020 May 18. doi: 10.1080/15592294.2020.1767323

PMCID:: PMC7595634

Abstract Article PDF–2.5M

Select item 747962019.

Single-cell transcriptome maps of myeloid blood cell lineages in Drosophila

Bumsik Cho, Sang-Ho Yoon, Daewon Lee, Ferdinand Koranteng, Sudhir Gopal Tattikota, Nuri Cha, Mingyu Shin, Hobin Do, Yanhui Hu, Sue Young Oh, Daehan Lee, A. Vipin Menon, Seok Jun Moon, Norbert Perrimon, Jin-Wu Nam, Jiwon Shim

Nat Commun. 2020; 11: 4483. Published online 2020 Sep 8. doi: 10.1038/s41467-020-18135-y