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Select item 105031901.

Amyloid fibril proteomics of AD brains reveals modifiers of aggregation and toxicity

Arun Upadhyay, Deepak Chhangani, Nalini R. Rao, Julia Kofler, Robert Vassar, Diego E. Rincon-Limas, Jeffrey N. Savas

Mol Neurodegener. 2023; 18: 61. Published online 2023 Sep 14. doi: 10.1186/s13024-023-00654-z

PMCID:: PMC10503190

Abstract Article PDF–8.6M

Select item 103323242.

The identification of protein and RNA interactors of the splicing factor Caper in the adult Drosophila nervous system

M. Brandon Titus, Adeline W. Chang, Niko Popitsch, Christopher C. Ebmeier, Jeremy M. Bono, Eugenia C. Olesnicky

Front Mol Neurosci. 2023; 16: 1114857. Published online 2023 Jun 23. doi: 10.3389/fnmol.2023.1114857

PMCID:: PMC10332324

Abstract Article PDF–4.5M

Select item 93176553.

Dynamics of huntingtin protein interactions in the striatum identifies candidate modifiers of Huntington’s disease

Todd M. Greco, Christopher Secker, Eduardo Silva Ramos, Joel D. Federspiel, Jeh-Ping Liu, Alma M. Perez, Ismael Al-Ramahi, Jeffrey P. Cantle, Jeffrey B. Carroll, Juan Botas, Scott O. Zeitlin, Erich E. Wanker, Ileana M. Cristea

Cell Syst. Author manuscript; available in PMC 2023 Apr 20.

Published in final edited form as: Cell Syst. 2022 Apr 20; 13(4): 304–320.e5. Published online 2022 Feb 10. doi: 10.1016/j.cels.2022.01.005

PMCID:: PMC9317655

Abstract Article PDF–4.2M

Select item 92019114.

Drosophila Relish Activating lncRNA-CR33942 Transcription Facilitates Antimicrobial Peptide Expression in Imd Innate Immune Response

Hongjian Zhou, Shanshan Wu, Li Liu, Ruimin Li, Ping Jin, Shengjie Li

Front Immunol. 2022; 13: 905899. Published online 2022 Jun 2. doi: 10.3389/fimmu.2022.905899

PMCID:: PMC9201911

Abstract Article PDF–8.6M

Select item 89833905.

Drosophila functional screening of de novo variants in autism uncovers damaging variants and facilitates discovery of rare neurodevelopmental diseases

Paul C. Marcogliese, Samantha L. Deal, Jonathan Andrews, J. Michael Harnish, V. Hemanjani Bhavana, Hillary K. Graves, Sharayu Jangam, Xi Luo, Ning Liu, Danqing Bei, Yu-Hsin Chao, Brooke Hull, Pei-Tseng Lee, Hongling Pan, Pradnya Bhadane, Mei-Chu Huang, Colleen M. Longley, Hsiao-Tuan Chao, Hyung-lok Chung, Nele A. Haelterman, Oguz Kanca, Sathiya N. Manivannan, Linda Z. Rossetti, Ryan J. German, Amanda Gerard, Eva Maria Christina Schwaibold, Sarah Fehr, Renzo Guerrini, Annalisa Vetro, Eleina England, Chaya N. Murali, Tahsin Stefan Barakat, Marieke F. van Dooren, Martina Wilke, Marjon van Slegtenhorst, Gaetan Lesca, Isabelle Sabatier, Nicolas Chatron, Catherine A. Brownstein, Jill A. Madden, Pankaj B. Agrawal, Boris Keren, Thomas Courtin, Laurence Perrin, Melanie Brugger, Timo Roser, Steffen Leiz, Frederic Tran Mau-Them, Julian Delanne, Elena Sukarova-Angelovska, Slavica Trajkova, Erik Rosenhahn, Vincent Strehlow, Konrad Platzer, Roberto Keller, Lisa Pavinato, Alfredo Brusco, Jill A. Rosenfeld, Ronit Marom, Michael F. Wangler, Shinya Yamamoto

Cell Rep. Author manuscript; available in PMC 2022 Apr 6.

Published in final edited form as: Cell Rep. 2022 Mar 15; 38(11): 110517. doi: 10.1016/j.celrep.2022.110517

PMCID:: PMC8983390

Abstract Article PDF–2.9M

Select item 84424456.

The gut-microbiota-brain axis in autism: what Drosophila models can offer?

Safa Salim, Ayesha Banu, Amira Alwa, Swetha B. M. Gowda, Farhan Mohammad

J Neurodev Disord. 2021; 13: 37. Published online 2021 Sep 15. doi: 10.1186/s11689-021-09378-x

PMCID:: PMC8442445

Abstract Article PDF–1.9M

Select item 82756727.

Dysregulated CRMP Mediates Circadian Deficits in a Drosophila Model of Fragile X Syndrome

Juan Zhao, Jin Xue, Tengfei Zhu, Hua He, Huaixing Kang, Xuan Jiang, Wen Huang, Ranhui Duan

Neurosci Bull. 2021 Jul; 37(7): 973–984. Published online 2021 Apr 15. doi: 10.1007/s12264-021-00682-z

PMCID:: PMC8275672

Abstract Article PDF–1.1M

Select item 82050638.

Sunday Driver Mediates Multi-Compartment Golgi Outposts Defects Induced by Amyloid Precursor Protein

Qianqian Du, Jin Chang, Guo Cheng, Yinyin Zhao, Wei Zhou

Front Neurosci. 2021; 15: 673684. Published online 2021 Jun 1. doi: 10.3389/fnins.2021.673684

PMCID:: PMC8205063

Abstract Article PDF–4.4M

Select item 69615789.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 608240110.

High-throughput functional analysis distinguishes pathogenic, nonpathogenic, and compensatory transcriptional changes in a neurodegenerative disorder

Ismael Al-Ramahi, Boxun Lu, Simone Di Paola, Kaifang Pang, Maria de Haro, Ivana Peluso, Tatiana Gallego-Flores, Nazish T. Malik, Kelly Erikson, Benjamin A. Bleiberg, Matthew Avalos, George Fan, Laura Elizabeth Rivers, Andrew M. Laitman, Javier R. Diaz-García, Marc Hild, James Palacino, Zhandong Liu, Diego L. Medina, Juan Botas

Cell Syst. Author manuscript; available in PMC 2019 Jul 25.

Published in final edited form as: Cell Syst. 2018 Jul 25; 7(1): 28–40.e4. Published online 2018 Jun 20. doi: 10.1016/j.cels.2018.05.010

PMCID:: PMC6082401

Abstract Article PDF–2.3M

Select item 570780511.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Abstract Article PDF–3.2M

Select item 568900212.

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster

Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira

RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117

PMCID:: PMC5689002

Abstract Article PDF–4.0M

Select item 539197013.

Comparison of independent screens on differentially vulnerable motor neurons reveals alpha-synuclein as a common modifier in motor neuron diseases

Rachel A. Kline, Kevin A. Kaifer, Erkan Y. Osman, Francesco Carella, Ariana Tiberi, Jolill Ross, Giuseppa Pennetta, Christian L. Lorson, Lyndsay M. Murray

PLoS Genet. 2017 Mar; 13(3): e1006680. Published online 2017 Mar 31. doi: 10.1371/journal.pgen.1006680

PMCID:: PMC5391970

Abstract Article PDF–1.5M

Select item 533337214.

Nociceptor-enriched genes required for normal thermal nociception

Ken Honjo, Stephanie E. Mauthner, Yu Wang, J.H. Pate Skene, W. Daniel Tracey, Jr.

Cell Rep. Author manuscript; available in PMC 2017 Mar 2.

Published in final edited form as: Cell Rep. 2016 Jul 12; 16(2): 295–303. Published online 2016 Jun 23. doi: 10.1016/j.celrep.2016.06.003

PMCID:: PMC5333372

Abstract Article PDF–1.6M

Select item 513503015.

Bilaterian Giant Ankyrins Have a Common Evolutionary Origin and Play a Conserved Role in Patterning the Axon Initial Segment

Timothy Jegla, Michelle M. Nguyen, Chengye Feng, Daniel J. Goetschius, Esteban Luna, Damian B. van Rossum, Bishoy Kamel, Aditya Pisupati, Elliott S. Milner, Melissa M. Rolls

PLoS Genet. 2016 Dec; 12(12): e1006457. Published online 2016 Dec 2. doi: 10.1371/journal.pgen.1006457

PMCID:: PMC5135030

Abstract Article PDF–5.1M

Select item 473800516.

Proteome-wide dataset supporting the study of ancient metazoan macromolecular complexes

Sadhna Phanse, Cuihong Wan, Blake Borgeson, Fan Tu, Kevin Drew, Greg Clark, Xuejian Xiong, Olga Kagan, Julian Kwan, Alexandr Bezginov, Kyle Chessman, Swati Pal, Graham Cromar, Ophelia Papoulas, Zuyao Ni, Daniel R. Boutz, Snejana Stoilova, Pierre C. Havugimana, Xinghua Guo, Ramy H. Malty, Mihail Sarov, Jack Greenblatt, Mohan Babu, W. Brent Derry, Elisabeth R. Tillier, John B. Wallingford, John Parkinson, Edward M. Marcotte, Andrew Emili

Data Brief. 2016 Mar; 6: 715–721. Published online 2015 Dec 12. doi: 10.1016/j.dib.2015.11.062

PMCID:: PMC4738005

Abstract Article PDF–205K

Select item 460415417.

Proteomic Analysis of the Ubiquitin Landscape in the Drosophila Embryonic Nervous System and the Adult Photoreceptor Cells

Juanma Ramirez, Aitor Martinez, Benoit Lectez, So Young Lee, Maribel Franco, Rosa Barrio, Gunnar Dittmar, Ugo Mayor

PLoS One. 2015; 10(10): e0139083. Published online 2015 Oct 13. doi: 10.1371/journal.pone.0139083

PMCID:: PMC4604154

Abstract Article PDF–3.1M

Select item 457928918.

Gene expression profiling of brakeless mutant Drosophila embryos

Filip Crona, Bhumica Singla, Mattias Mannervik

Data Brief. 2015 Dec; 5: 134–137. Published online 2015 Sep 5. doi: 10.1016/j.dib.2015.08.033

PMCID:: PMC4579289

Abstract Article PDF–284K

Select item 452833019.

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders

Madeline A. Crosby, L. Sian Gramates, Gilberto dos Santos, Beverley B. Matthews, Susan E. St. Pierre, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, David B. Emmert, Susan M. Russo, William M. Gelbart, the FlyBase Consortium

G3 (Bethesda) 2015 Aug; 5(8): 1737–1749. Published online 2015 Jun 24. doi: 10.1534/g3.115.018937

PMCID:: PMC4528330

Abstract Article PDF–2.2M

Select item 452832920.

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data

Beverley B. Matthews, Gilberto dos Santos, Madeline A. Crosby, David B. Emmert, Susan E. St. Pierre, L. Sian Gramates, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, Victor Strelets, Susan M. Russo, William M. Gelbart, the FlyBase Consortium

G3 (Bethesda) 2015 Aug; 5(8): 1721–1736. Published online 2015 Jun 24. doi: 10.1534/g3.115.018929

PMCID:: PMC4528329

Abstract Article PDF–4.9M

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