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Select item 108835461.

Nazo, the Drosophila homolog of the NBIA-mutated protein–c19orf12, is required for triglyceride homeostasis

Perinthottathil Sreejith, Sara Lolo, Kristen R. Patten, Maduka Gunasinghe, Neya More, Leo J. Pallanck, Rajnish Bharadwaj

PLoS Genet. 2024 Feb; 20(2): e1011137. Published online 2024 Feb 9. doi: 10.1371/journal.pgen.1011137

PMCID:: PMC10883546

Abstract Article PDF–4.2M

Select item 108405142.

COPI-regulated mitochondria-ER contact site formation maintains axonal integrity

Daniel C. Maddison, Bilal Malik, Leonardo Amadio, Dana M. Bis-Brewer, Stephan Züchner, Owen M. Peters, Gaynor A. Smith

Cell Rep. 2023 Aug 29; 42(8): 112883. Published online 2023 Jul 26. doi: 10.1016/j.celrep.2023.112883

PMCID:: PMC10840514

Abstract Article

Select item 105695923.

Genomes from historical Drosophila melanogaster specimens illuminate adaptive and demographic changes across more than 200 years of evolution

Max Shpak, Hamid R. Ghanavi, Jeremy D. Lange, John E. Pool, Marcus C. Stensmyr

PLoS Biol. 2023 Oct; 21(10): e3002333. Published online 2023 Oct 12. doi: 10.1371/journal.pbio.3002333

PMCID:: PMC10569592

Abstract Article PDF–3.5M

Select item 103016554.

The Janus-Faced Role of Lipid Droplets in Aging: Insights from the Cellular Perspective

Nikolaus Bresgen, Melanie Kovacs, Angelika Lahnsteiner, Thomas Klaus Felder, Mark Rinnerthaler

Biomolecules. 2023 Jun; 13(6): 912. Published online 2023 May 30. doi: 10.3390/biom13060912

PMCID:: PMC10301655

Abstract Article PDF–2.3M

Select item 101086055.

Drosophila embryos spatially sort their nutrient stores to facilitate their utilization

Marcus D. Kilwein, Matthew R. Johnson, Jonathon M. Thomalla, Anthony P. Mahowald, Michael A. Welte

Development. 2023 Oct 15; 150(20): dev201423. Published online 2023 Mar 17. doi: 10.1242/dev.201423

PMCID:: PMC10108605

Abstract Article

Select item 100722756.

Drosophila SPG12 ortholog, reticulon-like 1, governs presynaptic ER organization and Ca²⁺ dynamics

Juan José Pérez-Moreno, Rebecca C. Smith, Megan K. Oliva, Filomena Gallo, Shainy Ojha, Karin H. Müller, Cahir J. O’Kane

J Cell Biol. 2023 Jun 5; 222(6): e202112101. Published online 2023 Mar 23. doi: 10.1083/jcb.202112101

PMCID:: PMC10072275

Abstract Article PDF–12M

Select item 94814667.

Identification of two pathways mediating protein targeting from ER to lipid droplets

Jiunn Song, Arda Mizrak, Chia-Wei Lee, Marcelo Cicconet, Zon Weng Lai, Wei-Chun Tang, Chieh-Han Lu, Stephanie E. Mohr, Robert V. Farese, Jr., Tobias C. Walther

Nat Cell Biol. 2022; 24(9): 1364–1377. Published online 2022 Sep 1. doi: 10.1038/s41556-022-00974-0

PMCID:: PMC9481466

Abstract Article PDF–10M

Select item 87245778.

Origin and Development of the Adipose Tissue, a Key Organ in Physiology and Disease

Esmeralda Parra-Peralbo, Ana Talamillo, Rosa Barrio

Front Cell Dev Biol. 2021; 9: 786129. Published online 2021 Dec 21. doi: 10.3389/fcell.2021.786129

PMCID:: PMC8724577

Abstract Article PDF–1.5M

Select item 81213329.

Adipose triglyceride lipase protects renal cell endocytosis in a Drosophila dietary model of chronic kidney disease

Aleksandra Lubojemska, M. Irina Stefana, Sebastian Sorge, Andrew P. Bailey, Lena Lampe, Azumi Yoshimura, Alana Burrell, Lucy Collinson, Alex P. Gould

PLoS Biol. 2021 May; 19(5): e3001230. Published online 2021 May 4. doi: 10.1371/journal.pbio.3001230

PMCID:: PMC8121332

Abstract Article PDF–4.1M

Select item 769665510.

Determinants of endoplasmic reticulum-to-lipid droplet protein targeting

Maria-Jesus Olarte, Siyoung Kim, Morris E. Sharp, Jessica M.J. Swanson, Robert V. Farese, Jr., Tobias C. Walther

Dev Cell. Author manuscript; available in PMC 2021 Aug 24.

Published in final edited form as: Dev Cell. 2020 Aug 24; 54(4): 471–487.e7. Published online 2020 Jul 29. doi: 10.1016/j.devcel.2020.07.001

PMCID:: PMC7696655

Abstract Article PDF–2.5M

Select item 761070311.

A SuperFamily-Wide Activity Atlas of Serine Hydrolases in Drosophila Melanogaster

Kundan Kumar, Amol Mhetre, Girish S. Ratnaparkhi, Siddhesh S. Kamat

Biochemistry. Author manuscript; available in PMC 2021 Oct 27.

Published in final edited form as: Biochemistry. 2021 Apr 27; 60(16): 1312–1324. Published online 2021 Apr 7. doi: 10.1021/acs.biochem.1c00171

PMCID:: PMC7610703

Abstract Article PDF–1.7M

Select item 743884912.

Endoplasmic Reticulum Lumenal Indicators in Drosophila Reveal Effects of HSP-Related Mutations on Endoplasmic Reticulum Calcium Dynamics

Megan K. Oliva, Juan José Pérez-Moreno, Jillian O’Shaughnessy, Trevor J. Wardill, Cahir J. O’Kane

Front Neurosci. 2020; 14: 816. Published online 2020 Aug 10. doi: 10.3389/fnins.2020.00816

PMCID:: PMC7438849

Abstract Article PDF–2.2M

Select item 696157813.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 570780514.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Abstract Article PDF–3.2M

Select item 568900215.

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster

Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira

RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117

PMCID:: PMC5689002

Abstract Article PDF–4.0M

Select item 557692116.

Modeling of axonal endoplasmic reticulum network by spastic paraplegia proteins

Belgin Yalçın, Lu Zhao, Martin Stofanko, Niamh C O'Sullivan, Zi Han Kang, Annika Roost, Matthew R Thomas, Sophie Zaessinger, Olivier Blard, Alex L Patto, Anood Sohail, Valentina Baena, Mark Terasaki, Cahir J O'Kane

eLife. 2017; 6: e23882. Published online 2017 Jul 25. doi: 10.7554/eLife.23882