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Select item 116102471.

Human GLP1R variants affecting GLP1R cell surface expression are associated with impaired glucose control and increased adiposity

Wenwen Gao, Lei Liu, Eunna Huh, Florence Gbahou, Erika Cecon, Masaya Oishma, Ludivine Houzé, Panagiotis Katsonis, Alan Hegron, Zhiran Fan, Guofei Hou, Guillaume Charpentier, Mathilde Boissel, Mehdi Derhourhi, Michel Marre, Beverley Balkau, Philippe Froguel, Raphael Scharfmann, Olivier Lichtarge, Julie Dam, Amélie Bonnefond, Jianfeng Liu, Ralf Jockers

Nat Metab. Author manuscript; available in PMC 2024 Dec 2.

Published in final edited form as: Nat Metab. 2023 Oct; 5(10): 1673–1684. Published online 2023 Sep 14. doi: 10.1038/s42255-023-00889-6

PMCID:: PMC11610247

Abstract Article PDF–8.3M

Select item 110501472.

Association between the GLP1R A316T Mutation and Adolescent Idiopathic Scoliosis in French Canadian and Italian Cohorts

Émilie Normand, Anita Franco, Stefan Parent, Giovanni Lombardi, Marco Brayda-Bruno, Alessandra Colombini, Alain Moreau, Valérie Marcil

Genes (Basel) 2024 Apr; 15(4): 481. Published online 2024 Apr 11. doi: 10.3390/genes15040481

PMCID:: PMC11050147

Abstract Article PDF–261K

Select item 109164663.

A systematic review of GLP-1 on anthropometrics, metabolic and endocrine parameters in patients with PCOS

Salwa Bader, Rahila Bhatti, Bashair Mussa, Salah Abusanana

Womens Health (Lond) 2024; 20: 17455057241234530. Published online 2024 Mar 5. doi: 10.1177/17455057241234530

PMCID:: PMC10916466

Abstract Article PDF–576K

Select item 108429864.

Glucagon-like peptide-1 receptor pathway attenuates platelet activation in aspirin-exacerbated respiratory disease

Dinah Foer, Taneem Amin, Jun Nagai, Yumi Tani, Chunli Feng, Tao Liu, Dawn C. Newcomb, Juying Lai, Hiroaki Hayashi, William E. Snyder, Alanna McGill, Anabel Lin, Tanya Laidlaw, Kevin D. Niswender, Joshua A. Boyce, Katherine N. Cahill

J Immunol. Author manuscript; available in PMC 2024 Dec 15.

Published in final edited form as: J Immunol. 2023 Dec 15; 211(12): 1806–1813. doi: 10.4049/jimmunol.2300102

PMCID:: PMC10842986

Abstract Article PDF–929K

Select item 107211015.

Polymorphisms in the glucagon-like peptide-1 receptor gene and their interactions on the risk of osteoporosis in postmenopausal Chinese women

Chang Liu, Xiaoxue Bao, Yawei Tian, Peng Xue, Yan Wang, Yukun Li

PLoS One. 2023; 18(12): e0295451. Published online 2023 Dec 14. doi: 10.1371/journal.pone.0295451

PMCID:: PMC10721101

Abstract Article PDF–635K

Select item 106453896.

Glucagon-like peptide-1 receptor blockade impairs islet secretion and glucose metabolism in humans

Andrew A. Welch, Rahele A. Farahani, Aoife M. Egan, Marcello C. Laurenti, Maya Zeini, Max Vella, Kent R. Bailey, Claudio Cobelli, Chiara Dalla Man, Aleksey Matveyenko, Adrian Vella

J Clin Invest. 2023 Nov 15; 133(22): e173495. Published online 2023 Nov 15. doi: 10.1172/JCI173495

PMCID:: PMC10645389

Abstract Article PDF–1018K

Select item 106068007.

Immunohistochemical Glucagon-like Peptide-1 Receptor Expression in Human Insulinomas

Tiina Vesterinen, Elina Peltola, Helena Leijon, Päivi Hannula, Heini Huhtala, Markus J. Mäkinen, Lasse Nieminen, Elina Pirinen, Mikko Rönty, Mirva Söderström, Pia Jaatinen, Johanna Arola

Int J Mol Sci. 2023 Oct; 24(20): 15164. Published online 2023 Oct 13. doi: 10.3390/ijms242015164

PMCID:: PMC10606800

Abstract Article PDF–1.1M

Select item 105840038.

Rare Heterozygous Loss-of-Function Variants in the Human GLP-1 Receptor Are Not Associated With Cardiometabolic Phenotypes

Josefine U Melchiorsen, Kimmie V Sørensen, Jette Bork-Jensen, Hüsün S Kizilkaya, Lærke S Gasbjerg, Alexander S Hauser, Jørgen Rungby, Henrik T Sørensen, Allan Vaag, Jens S Nielsen, Oluf Pedersen, Allan Linneberg, Bolette Hartmann, Anette P Gjesing, Jens J Holst, Torben Hansen, Mette M Rosenkilde, Niels Grarup

J Clin Endocrinol Metab. 2023 Nov; 108(11): 2821–2833. Published online 2023 May 26. doi: 10.1210/clinem/dgad290

PMCID:: PMC10584003

Abstract Article

Select item 103981369.

Real-World Glycemic Control from GLP-1RA Therapy with and Without Concurrent Insulin in Patients with Type 2 Diabetes

Mukul Singhal, Sudhir Unni, Marisa Schauerhamer, Hiep Nguyen, Jeff Hurd, Carrie McAdam-Marx

J Manag Care Spec Pharm. 2017 Mar; 23(3): 10.18553/jmcp.2017.16334. doi: 10.18553/jmcp.2017.16334

PMCID:: PMC10398136

Abstract Article PDF–264K

Select item 1015611310.

Divergent acute versus prolonged pharmacological GLP-1R responses in adult β cell–specific β-arrestin 2 knockout mice

Stavroula Bitsi, Liliane El Eid, Yusman Manchanda, Affiong I. Oqua, Nimco Mohamed, Ben Hansen, Kinga Suba, Guy A. Rutter, Victoria Salem, Ben Jones, Alejandra Tomas

Sci Adv. 2023 May; 9(18): eadf7737. Published online 2023 May 3. doi: 10.1126/sciadv.adf7737

PMCID:: PMC10156113

Abstract Article PDF–3.0M

Select item 1001603811.

Enhanced Endosomal Signaling and Desensitization of GLP-1R vs GIPR in Pancreatic Beta Cells

Yusman Manchanda, Stavroula Bitsi, Shiqian Chen, Johannes Broichhagen, Jorge Bernardino de la Serna, Ben Jones, Alejandra Tomas

Endocrinology. 2023 May; 164(5): bqad028. Published online 2023 Feb 12. doi: 10.1210/endocr/bqad028

PMCID:: PMC10016038

Abstract Article

Select item 986531912.

GLP-1 Receptor Agonists in Non-Alcoholic Fatty Liver Disease: Current Evidence and Future Perspectives

Riccardo Nevola, Raffaella Epifani, Simona Imbriani, Giovanni Tortorella, Concetta Aprea, Raffaele Galiero, Luca Rinaldi, Raffaele Marfella, Ferdinando Carlo Sasso

Int J Mol Sci. 2023 Jan; 24(2): 1703. Published online 2023 Jan 15. doi: 10.3390/ijms24021703

PMCID:: PMC9865319

Abstract Article PDF–884K

Select item 974013813.

Glucagon-like Peptide-1 Receptor in the Human Hypothalamus Is Associated with Body Mass Index and Colocalizes with the Anorexigenic Neuropeptide Nucleobindin-2/Nesfatin-1

Aristea Psilopanagioti, Sofia Nikou, Souzana Logotheti, Marina Arbi, Dionysios V. Chartoumpekis, Helen Papadaki

Int J Mol Sci. 2022 Dec; 23(23): 14899. Published online 2022 Nov 28. doi: 10.3390/ijms232314899

PMCID:: PMC9740138

Abstract Article PDF–6.1M

Select item 971275314.

Decreased expression of Glucagon-like peptide-1 receptor and Sodium-glucose co-transporter 2 in patients with proliferative diabetic retinopathy

Hui Chen, Xiongze Zhang, Nanying Liao, Yuying Ji, Lan Mi, Yuhong Gan, Yongyue Su, Feng Wen

Front Endocrinol (Lausanne) 2022; 13: 1020252. Published online 2022 Nov 17. doi: 10.3389/fendo.2022.1020252

PMCID:: PMC9712753

Abstract Article PDF–5.6M

Select item 962653315.

Association of GLP1R variants rs2268641 and rs6923761 with obesity and other metabolic parameters in a Polish cohort

Joanna Michałowska, Ewa Miller-Kasprzak, Agnieszka Seraszek-Jaros, Adrianna Mostowska, Paweł Bogdański

Front Endocrinol (Lausanne) 2022; 13: 1000185. Published online 2022 Oct 19. doi: 10.3389/fendo.2022.1000185

PMCID:: PMC9626533

Abstract Article PDF–516K

Select item 952345416.

Differential effects of glucose‐dependent insulinotropic polypeptide receptor/glucagon‐like peptide‐1 receptor heteromerization on cell signaling when expressed in HEK‐293 cells

Bashaier Al‐Zaid, Siby Chacko, Charles Ifeamalume Ezeamuzie, Moritz Bünemann, Cornelius Krasel, Tina Karimian, Peter Lanzerstorfer, Suleiman Al‐Sabah

Pharmacol Res Perspect. 2022 Oct; 10(5): e01013. Published online 2022 Sep 30. doi: 10.1002/prp2.1013

PMCID:: PMC9523454

Abstract Article PDF–2.9M

Select item 945562517.

Anti-Inflammatory Effects of GLP-1 Receptor Activation in the Brain in Neurodegenerative Diseases

Yolanda Diz-Chaves, Zainab Mastoor, Carlos Spuch, Lucas C. González-Matías, Federico Mallo

Int J Mol Sci. 2022 Sep; 23(17): 9583. Published online 2022 Aug 24. doi: 10.3390/ijms23179583

PMCID:: PMC9455625

Abstract Article PDF–1.6M

Select item 938771718.

Association of GLP1R Polymorphisms With the Incretin Response

Edgar G Dorsey-Trevino, Varinderpal Kaur, Josep M Mercader, Jose C Florez, Aaron Leong

J Clin Endocrinol Metab. 2022 Sep; 107(9): 2580–2588. Published online 2022 Jun 20. doi: 10.1210/clinem/dgac374

PMCID:: PMC9387717

Abstract Article

Select item 933832319.

Differential association between the GLP1R gene variants and brain functional connectivity according to the severity of alcohol use

Mehdi Farokhnia, Samantha J. Fede, Erica N. Grodin, Brittney D. Browning, Madeline E. Crozier, Melanie L. Schwandt, Colin A. Hodgkinson, Reza Momenan, Lorenzo Leggio

Sci Rep. 2022; 12: 13027. Published online 2022 Jul 29. doi: 10.1038/s41598-022-17190-3

PMCID:: PMC9338323

Abstract Article PDF–1.4M

Select item 884282720.

Evaluating the GLP-1 receptor in managing asthma

Ashley Y. Wu, Katherine N. Cahill, Shinji Toki, R. Stokes Peebles, Jr.

Curr Opin Allergy Clin Immunol. Author manuscript; available in PMC 2023 Feb 1.

Published in final edited form as: Curr Opin Allergy Clin Immunol. 2022 Feb 1; 22(1): 36–41. doi: 10.1097/ACI.0000000000000797

PMCID:: PMC8842827

Abstract Article PDF–688K

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