PMC Links for GEO Profiles (Select 40666604) - PMC

Select item 95200241.

Alkaline-sensitive two-pore domain potassium channels form functional heteromers in pancreatic β-cells

Lamyaa Khoubza, Nicolas Gilbert, Eun-Jin Kim, Franck C. Chatelain, Sylvain Feliciangeli, Sophie Abelanet, Dawon Kang, Florian Lesage, Delphine Bichet

J Biol Chem. 2022 Oct; 298(10): 102447. Published online 2022 Sep 5. doi: 10.1016/j.jbc.2022.102447

PMCID:: PMC9520024

Abstract Article PDF–2.2M

Select item 84100892.

A KCNK16 mutation causing TALK-1 gain of function is associated with maturity-onset diabetes of the young

Sarah M. Graff, Stephanie R. Johnson, Paul J. Leo, Prasanna K. Dadi, Matthew T. Dickerson, Arya Y. Nakhe, Aideen M. McInerney-Leo, Mhairi Marshall, Karolina E. Zaborska, Charles M. Schaub, Matthew A. Brown, David A. Jacobson, Emma L. Duncan

JCI Insight. 2021 Jul 8; 6(13): e138057. Published online 2021 Jul 8. doi: 10.1172/jci.insight.138057

PMCID:: PMC8410089

Abstract Article PDF–2.0M

Select item 81650303.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 61666824.

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck

Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924

PMCID:: PMC6166682

Abstract Article PDF–3.8M

Select item 56728045.

TALK-1 channels control β cell endoplasmic reticulum Ca²⁺ homeostasis

Nicholas C. Vierra, Prasanna K. Dadi, Sarah C. Milian, Matthew T. Dickerson, Kelli L. Jordan, Patrick Gilon, David A. Jacobson

Sci Signal. Author manuscript; available in PMC 2018 Mar 19.

Published in final edited form as: Sci Signal. 2017 Sep 19; 10(497): eaan2883. Published online 2017 Sep 19. doi: 10.1126/scisignal.aan2883

PMCID:: PMC5672804

Abstract Article PDF–3.0M

Select item 55316116.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 53897967.

Osteopontin activates the diabetes-associated potassium channel TALK-1 in pancreatic β-cells

Matthew T. Dickerson, Nicholas C. Vierra, Sarah C. Milian, Prasanna K. Dadi, David A. Jacobson

PLoS One. 2017; 12(4): e0175069. Published online 2017 Apr 12. doi: 10.1371/journal.pone.0175069

PMCID:: PMC5389796

Abstract Article PDF–2.1M

Select item 47718738.

A Non-canonical Voltage-Sensing Mechanism Controls Gating in K2P K⁺ Channels

Marcus Schewe, Ehsan Nematian-Ardestani, Han Sun, Marianne Musinszki, Sönke Cordeiro, Giovanna Bucci, Bert L. de Groot, Stephen J. Tucker, Markus Rapedius, Thomas Baukrowitz

Cell. 2016 Feb 25; 164(5): 937–949. doi: 10.1016/j.cell.2016.02.002

PMCID:: PMC4771873

Abstract Article PDF–4.6M

Select item 46172119.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 461397810.

Type 2 Diabetes–Associated K⁺ Channel TALK-1 Modulates β-Cell Electrical Excitability, Second-Phase Insulin Secretion, and Glucose Homeostasis

Nicholas C. Vierra, Prasanna K. Dadi, Imju Jeong, Matthew Dickerson, David R. Powell, David A. Jacobson

Diabetes. 2015 Nov; 64(11): 3818–3828. Published online 2015 Aug 3. doi: 10.2337/db15-0280

PMCID:: PMC4613978

Abstract Article PDF–3.5M

Select item 426658811.

A proteome-scale map of the human interactome network

Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal

Cell. Author manuscript; available in PMC 2015 Nov 20.

Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050

PMCID:: PMC4266588

Abstract Article PDF–3.1M

Select item 396961212.

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium, Asian Genetic Epidemiology Network Type 2 Diabetes (AGEN-T2D) Consortium, South Asian Type 2 Diabetes (SAT2D) Consortium, Mexican American Type 2 Diabetes (MAT2D) Consortium, Type 2 Diabetes Genetic Exploration by Next-generation sequencing in multi-Ethnic Samples (T2D-GENES) Consortium

Nat Genet. Author manuscript; available in PMC 2014 Sep 1.

Published in final edited form as: Nat Genet. 2014 Mar; 46(3): 234–244. Published online 2014 Feb 9. doi: 10.1038/ng.2897

PMCID:: PMC3969612

Abstract Article PDF–725K

Select item 358239813.

Meta-analysis of genome-wide association studies identifies 8 new loci for type 2 diabetes in East Asians

Yoon Shin Cho, Chien-Hsiun Chen, Cheng Hu, Jirong Long, Rick Twee Hee Ong, Xueling Sim, Fumihiko Takeuchi, Ying Wu, Min Jin Go, Toshimasa Yamauchi, Yi-Cheng Chang, Soo Heon Kwak, Ronald C.W. Ma, Ken Yamamoto, Linda S. Adair, Tin Aung, Qiuyin Cai, Li-Ching Chang, Yuan-Tsong Chen, Yutang Gao, Frank B. Hu, Hyung-Lae Kim, Sangsoo Kim, Young Jin Kim, Jeannette Jen-Mai Lee, Nanette R. Lee, Yun Li, Jian Jun Liu, Wei Lu, Jiro Nakamura, Eitaro Nakashima, Daniel Peng-Keat Ng, Wan Ting Tay, Fuu-Jen Tsai, Tien Yin Wong, Mitsuhiro Yokota, Wei Zheng, Rong Zhang, Congrong Wang, Wing Yee So, Keizo Ohnaka, Hiroshi Ikegami, Kazuo Hara, Young Min Cho, Nam H Cho, Tien-Jyun Chang, Yuqian Bao, Åsa K. Hedman, Andrew P. Morris, Mark I. McCarthy, DIAGRAM consortium, MuTHER consortium, Ryoichi Takayanagi, Kyong Soo Park, Weiping Jia, Lee-Ming Chuang, Juliana C.N. Chan, Shiro Maeda, Takashi Kadowaki, Jong-Young Lee, Jer-Yuarn Wu, Yik Ying Teo, E Shyong Tai, Xiao Ou Shu, Karen L. Mohlke, Norihiro Kato, Bok-Ghee Han, Mark Seielstad

Nat Genet. Author manuscript; available in PMC 2013 Feb 26.

Published in final edited form as: Nat Genet. 2011 Dec 11; 44(1): 67–72. Published online 2011 Dec 11. doi: 10.1038/ng.1019

PMCID:: PMC3582398

Abstract Article PDF–2.4M

Select item 317805914.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 251846215.

Regulation of two-pore-domain (K_2P) potassium leak channels by the tyrosine kinase inhibitor genistein

J Gierten, E Ficker, R Bloehs, K Schlömer, S Kathöfer, E Scholz, E Zitron, C Kiesecker, A Bauer, R Becker, H A Katus, C A Karle, D Thomas

Br J Pharmacol. 2008 Aug; 154(8): 1680–1690. Published online 2008 Jun 2. doi: 10.1038/bjp.2008.213

PMCID:: PMC2518462

Abstract Article PDF–347K

Select item 13924116.

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences

Mammalian Gene Collection (MGC) Program Team

Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16899–16903. Published online 2002 Dec 11. doi: 10.1073/pnas.242603899

PMCID:: PMC139241

Abstract Article PDF–118K

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