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Items: 1 to 20 of 145

1.
The amyloid precursor protein intracellular domain induces sleep disruptions and its nuclear localization fluctuates in circadian pacemaker neurons in Drosophila and mice
Dani M. Long, Olga Cravetchi, Eileen S. Chow, Charles Allen, Doris Kretzschmar
Neurobiol Dis. Author manuscript; available in PMC 2024 Mar 13.
Published in final edited form as: Neurobiol Dis. 2024 Mar; 192: 106429. Published online 2024 Feb 2. doi: 10.1016/j.nbd.2024.106429
PMCID:
PMC10932905
AbstractArticlePDF–3.3M
2.
RACK1 and IRE1 participate in the translational quality control of amyloid precursor protein in Drosophila models of Alzheimer’s disease
Yu Li, Dongyue Liu, Xuejing Zhang, Suman Rimal, Bingwei Lu, Shuangxi Li
J Biol Chem. 2024 Mar; 300(3): 105719. Published online 2024 Feb 2. doi: 10.1016/j.jbc.2024.105719
PMCID:
PMC10907166
AbstractArticlePDF–4.0M
3.
Simple model systems reveal conserved mechanisms of Alzheimer’s disease and related tauopathies
Yuwei Jiang, Lesley T. MacNeil
Mol Neurodegener. 2023; 18: 82. Published online 2023 Nov 10. doi: 10.1186/s13024-023-00664-x
PMCID:
PMC10638731
AbstractArticlePDF–2.9M
4.
Integrative analysis reveals a conserved role for the amyloid precursor protein in proteostasis during aging
Vanitha Nithianandam, Hassan Bukhari, Matthew J. Leventhal, Rachel A. Battaglia, Xianjun Dong, Ernest Fraenkel, Mel B. Feany
Nat Commun. 2023; 14: 7034. Published online 2023 Nov 3. doi: 10.1038/s41467-023-42822-1
PMCID:
PMC10624868
AbstractArticlePDF–7.6M
5.
The Drosophila homolog of APP promotes Dscam expression to drive axon terminal growth, revealing interaction between Down syndrome genes
Sarah Pizzano, Gabriella R. Sterne, Macy W. Veling, L. Amanda Xu, Ty Hergenreder, Bing Ye
Dis Model Mech. 2023 Sep 1; 16(9): dmm049725. Published online 2023 Sep 15. doi: 10.1242/dmm.049725
PMCID:
PMC10508694
AbstractArticle
6.
Genetic atlas of hygro-and thermosensory cells in the vinegar fly Drosophila melanogaster
Kristina Corthals, Vilma Andersson, Allison Churcher, Johan Reimegård, Anders Enjin
Sci Rep. 2023; 13: 15202. Published online 2023 Sep 14. doi: 10.1038/s41598-023-42506-2
PMCID:
PMC10502013
AbstractArticlePDF–5.5M
7.
N-Acetyltransferase 9 ameliorates Aβ42-mediated neurodegeneration in the Drosophila eye
Prajakta Deshpande, Anuradha Venkatakrishnan Chimata, Emily Snider, Aditi Singh, Madhuri Kango-Singh, Amit Singh
Cell Death Dis. 2023 Jul; 14(7): 478. Published online 2023 Jul 28. doi: 10.1038/s41419-023-05973-z
PMCID:
PMC10382493
AbstractArticlePDF–14M
8.
Drosophila melanogaster as a model to study autophagy in neurodegenerative diseases induced by proteinopathies
Stefania Santarelli, Chiara Londero, Alessia Soldano, Carlotta Candelaresi, Leonardo Todeschini, Luisa Vernizzi, Paola Bellosta
Front Neurosci. 2023; 17: 1082047. Published online 2023 May 18. doi: 10.3389/fnins.2023.1082047
PMCID:
PMC10232775
AbstractArticlePDF–2.4M
9.
Deciphering mechanisms of action of ACE inhibitors in neurodegeneration using Drosophila models of Alzheimer’s disease
Judy Ghalayini, Gabrielle L. Boulianne
Front Neurosci. 2023; 17: 1166973. Published online 2023 Apr 11. doi: 10.3389/fnins.2023.1166973
PMCID:
PMC10126366
AbstractArticlePDF–895K
10.
Reverse electron transfer is activated during aging and contributes to aging and age‐related disease
Suman Rimal, Ishaq Tantray, Yu Li, Tejinder Pal Khaket, Yanping Li, Sunil Bhurtel, Wen Li, Cici Zeng, Bingwei Lu
EMBO Rep. 2023 Apr; 24(4): e55548. Published online 2023 Feb 16. doi: 10.15252/embr.202255548
PMCID:
PMC10074108
AbstractArticlePDF–3.9M
11.
Fragile X mental retardation protein coordinates neuron-to-glia communication for clearance of developmentally transient brain neurons
Chunzhu Song, Kendal Broadie
Proc Natl Acad Sci U S A. 2023 Mar 21; 120(12): e2216887120. Published online 2023 Mar 15. doi: 10.1073/pnas.2216887120
PMCID:
PMC10041173
AbstractArticlePDF–2.8M
12.
Sleep benefits different stages of memory in Drosophila
Katie Marquand, Camilla Roselli, Isaac Cervantes-Sandoval, Tamara Boto
Front Physiol. 2023; 14: 1087025. Published online 2023 Jan 19. doi: 10.3389/fphys.2023.1087025
PMCID:
PMC9892949
AbstractArticlePDF–1.3M
13.
The making of the Drosophila mushroom body
Suewei Lin
Front Physiol. 2023; 14: 1091248. Published online 2023 Jan 13. doi: 10.3389/fphys.2023.1091248
PMCID:
PMC9880076
AbstractArticlePDF–2.2M
14.
Chromatin and transcriptomic profiling uncover dysregulation of the Tip60 HAT/HDAC2 epigenomic landscape in the neurodegenerative brain
Mariah Beaver, Bhanu Chandra Karisetty, Haolin Zhang, Akanksha Bhatnagar, Ellen Armour, Visha Parmar, Reshma Brown, Merry Xiang, Felice Elefant
Epigenetics. 2022; 17(7): 786–807. Published online 2021 Aug 9. doi: 10.1080/15592294.2021.1959742
PMCID:
PMC9336495
AbstractArticlePDF–3.5M
15.
γ-secretase promotes Drosophila postsynaptic development through the cleavage of a Wnt receptor
Lucas Restrepo, Alison DePew, Elizabeth Moese, Stephen Tymanskyj, Michael Parisi, Michael Aimino, Juan Carlos Duhart, Hong Fei, Timothy J. Mosca
Dev Cell. Author manuscript; available in PMC 2023 Jul 11.
Published in final edited form as: Dev Cell. 2022 Jul 11; 57(13): 1643–1660.e7. Published online 2022 Jun 1. doi: 10.1016/j.devcel.2022.05.006
PMCID:
PMC9283269
AbstractArticlePDF–3.8M
16.
The Nab2 RNA-binding protein patterns dendritic and axonal projections through a planar cell polarity-sensitive mechanism
Edwin B Corgiat, Sara M List, J Christopher Rounds, Dehong Yu, Ping Chen, Anita H Corbett, Kenneth H Moberg
G3 (Bethesda) 2022 Jun; 12(6): jkac100. Published online 2022 Apr 26. doi: 10.1093/g3journal/jkac100
PMCID:
PMC9157165
AbstractArticlePDF–1.9M
17.
Maintenance of mitochondrial integrity in midbrain dopaminergic neurons governed by a conserved developmental transcription factor
Federico Miozzo, Eva P. Valencia-Alarcón, Luca Stickley, Michaëla Majcin Dorcikova, Francesco Petrelli, Damla Tas, Nicolas Loncle, Irina Nikonenko, Peter Bou Dib, Emi Nagoshi
Nat Commun. 2022; 13: 1426. Published online 2022 Mar 17. doi: 10.1038/s41467-022-29075-0
PMCID:
PMC8931002
AbstractArticlePDF–6.9M
18.
The Alzheimer susceptibility gene BIN1 induces isoform-dependent neurotoxicity through early endosome defects
Erwan Lambert, Orthis Saha, Bruna Soares Landeira, Ana Raquel Melo de Farias, Xavier Hermant, Arnaud Carrier, Alexandre Pelletier, Johanna Gadaut, Lindsay Davoine, Cloé Dupont, Philippe Amouyel, Amélie Bonnefond, Frank Lafont, Farida Abdelfettah, Patrik Verstreken, Julien Chapuis, Nicolas Barois, Fabien Delahaye, Bart Dermaut, Jean-Charles Lambert, Marcos R. Costa, Pierre Dourlen
Acta Neuropathol Commun. 2022; 10: 4. Published online 2022 Jan 8. doi: 10.1186/s40478-021-01285-5
PMCID:
PMC8742943
AbstractArticlePDF–6.5M
19.
A stop or go switch: glycogen synthase kinase 3β phosphorylation of the kinesin 1 motor domain at Ser314 halts motility without detaching from microtubules
Rupkatha Banerjee, Piyali Chakraborty, Michael C. Yu, Shermali Gunawardena
Development. 2021 Dec 15; 148(24): dev199866. Published online 2021 Dec 23. doi: 10.1242/dev.199866
PMCID:
PMC8722386
AbstractArticle
20.
Integrative genome-wide analysis of dopaminergic neuron-specific PARIS expression in Drosophila dissects recognition of multiple PPAR-γ associated gene regulation
Volkan Yazar, Sung-Ung Kang, Shinwon Ha, Valina L. Dawson, Ted M. Dawson
Sci Rep. 2021; 11: 21500. Published online 2021 Nov 2. doi: 10.1038/s41598-021-00858-7
PMCID:
PMC8563805
AbstractArticlePDF–1.5M

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