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Select item 110349811.

Mrj is a chaperone of the Hsp40 family that regulates Orb2 oligomerization and long-term memory in Drosophila

Meghal Desai, Hemant, Ankita Deo, Jagyanseni Naik, Prathamesh Dhamale, Avinash Kshirsagar, Tania Bose, Amitabha Majumdar

PLoS Biol. 2024 Apr; 22(4): e3002585. Published online 2024 Apr 22. doi: 10.1371/journal.pbio.3002585

PMCID:: PMC11034981

Abstract Article PDF–4.0M

Select item 97509642.

An increase in mitochondrial TOM activates apoptosis to drive retinal neurodegeneration

Agalya Periasamy, Naomi Mitchell, Olga Zaytseva, Arjun S. Chahal, Jiamin Zhao, Peter M. Colman, Leonie M. Quinn, Jacqueline M. Gulbis

Sci Rep. 2022; 12: 21634. Published online 2022 Dec 14. doi: 10.1038/s41598-022-23280-z

PMCID:: PMC9750964

Abstract Article PDF–12M

Select item 94745453.

Mettl3-dependent m⁶A modification attenuates the brain stress response in Drosophila

Alexandra E. Perlegos, Emily J. Shields, Hui Shen, Kathy Fange Liu, Nancy M. Bonini

Nat Commun. 2022; 13: 5387. Published online 2022 Sep 14. doi: 10.1038/s41467-022-33085-3

PMCID:: PMC9474545

Abstract Article PDF–2.7M

Select item 92874264.

Fatty acid tryptamide from cacao elongates Drosophila melanogaster lifespan with sirtuin-dependent heat shock protein expression

Kiko Kanno, Yasunari Kayashima, Kazuji Tamura, Takako Miyara, Kento Baba, Megumi Koganei, Midori Natsume, Shinjiro Imai

Sci Rep. 2022; 12: 12080. Published online 2022 Jul 15. doi: 10.1038/s41598-022-16471-1

PMCID:: PMC9287426

Abstract Article PDF–2.1M

Select item 91363045.

Border cell polarity and collective migration require the spliceosome component Cactin

Guangxia Miao, Li Guo, Denise J. Montell

J Cell Biol. 2022 Jul 4; 221(7): e202202146. Published online 2022 May 25. doi: 10.1083/jcb.202202146

PMCID:: PMC9136304

Abstract Article PDF–7.3M

Select item 91143706.

Heat shock protein Grp78/BiP/HspA5 binds directly to TDP-43 and mitigates toxicity associated with disease pathology

Liberty François-Moutal, David Donald Scott, Andrew J. Ambrose, Christopher J. Zerio, Marina Rodriguez-Sanchez, Kumara Dissanayake, Danielle G. May, Jacob M. Carlson, Edward Barbieri, Aubin Moutal, Kyle J. Roux, James Shorter, Rajesh Khanna, Sami J. Barmada, Leeanne McGurk, May Khanna

Sci Rep. 2022; 12: 8140. Published online 2022 May 17. doi: 10.1038/s41598-022-12191-8

PMCID:: PMC9114370

Abstract Article PDF–2.0M

Select item 90195957.

Phylogenetic annotation of Drosophila melanogaster heat shock protein 70 genes

Gen Kaneko

MicroPubl Biol. 2022; 2022: 10.17912/micropub.biology.000558. Published online 2022 Apr 20. doi: 10.17912/micropub.biology.000558

PMCID:: PMC9019595

Abstract Article PDF–517K

Select item 86644868.

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349

PMCID:: PMC8664486

Abstract Article PDF–3.1M

Select item 83698379.

RNA kinase CLP1/Cbc regulates meiosis initiation in spermatogenesis

Jianbo Wu, Xin Li, Zhiyang Gao, Lin Pang, Xian Liu, Xiahe Huang, Yingchun Wang, Zhaohui Wang

Hum Mol Genet. 2021 Sep 1; 30(17): 1569–1578. Published online 2021 Apr 16. doi: 10.1093/hmg/ddab107

PMCID:: PMC8369837

Abstract Article PDF–2.2M

Select item 810494610.

Highly effective proximate labeling in Drosophila

Bo Zhang, Yuanbing Zhang, Ji-Long Liu

G3 (Bethesda) 2021 May; 11(5): jkab077. Published online 2021 Mar 16. doi: 10.1093/g3journal/jkab077

Correction in:: G3 (Bethesda). 2022 Mar; 12(3): jkac005.

PMCID:: PMC8104946

Abstract Article PDF–1.1M

Select item 799363211.

Identification of protein quality control regulators using a Drosophila model of TPI deficiency

Stacy L. Hrizo, Samantha L. Eicher, Tracey D. Myers, Ian McGrath, Andrew P. K. Wodrich, Hemanth Venkatesh, Daniel Manjooran, Sabrina Swoger, Kim Gagnon, Matthew Bruskin, Maria V. Lebedev, Sherry Zheng, Ana Vitantonio, Sungyoun Kim, Zachary J. Lamb, Andreas Vogt, Maura R.Z. Ruzhnikov, Michael J. Palladino

Neurobiol Dis. Author manuscript; available in PMC 2021 May 1.

Published in final edited form as: Neurobiol Dis. 2021 May; 152: 105299. Published online 2021 Feb 15. doi: 10.1016/j.nbd.2021.105299

PMCID:: PMC7993632

Abstract Article PDF–1.3M

Select item 790962912.

Cross-species identification of PIP5K1-, splicing- and ubiquitin-related pathways as potential targets for RB1-deficient cells

Andrey A. Parkhitko, Arashdeep Singh, Sharon Hsieh, Yanhui Hu, Richard Binari, Christopher J. Lord, Sridhar Hannenhalli, Colm J. Ryan, Norbert Perrimon

PLoS Genet. 2021 Feb; 17(2): e1009354. Published online 2021 Feb 16. doi: 10.1371/journal.pgen.1009354

PMCID:: PMC7909629

Abstract Article PDF–4.6M

Select item 696157813.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 675092614.

Large-scale RNAi screen identified Dhpr as a regulator of mitochondrial morphology and tissue homeostasis

Jia Zhou, Lingna Xu, Xiuying Duan, Wei Liu, Xiaocui Zhao, Xi Wang, Weina Shang, Xuefei Fang, Huan Yang, Lijun Jia, Jian Bai, Jiayao Zhao, Liquan Wang, Chao Tong

Sci Adv. 2019 Sep; 5(9): eaax0365. Published online 2019 Sep 18. doi: 10.1126/sciadv.aax0365

PMCID:: PMC6750926

Abstract Article PDF–14M

Select item 650653915.

Tissue-specific (ts)CRISPR as an efficient strategy for in vivo screening in Drosophila

Hagar Meltzer, Efrat Marom, Idan Alyagor, Oded Mayseless, Victoria Berkun, Netta Segal-Gilboa, Tamar Unger, David Luginbuhl, Oren Schuldiner

Nat Commun. 2019; 10: 2113. Published online 2019 May 8. doi: 10.1038/s41467-019-10140-0

PMCID:: PMC6506539

Abstract Article PDF–6.5M

Select item 607860416.

Human R1441C LRRK2 regulates the synaptic vesicle proteome and phosphoproteome in a Drosophila model of Parkinson’s disease

Md Shariful Islam, Hendrik Nolte, Wright Jacob, Anna B. Ziegler, Stefanie Pütz, Yael Grosjean, Karolina Szczepanowska, Aleksandra Trifunovic, Thomas Braun, Hermann Heumann, Rolf Heumann, Bernhard Hovemann, Darren J. Moore, Marcus Krüger

Hum Mol Genet. 2016 Dec 15; 25(24): 5365–5382. Published online 2016 Oct 29. doi: 10.1093/hmg/ddw352