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Items: 1 to 20 of 26

1.
Pregnane X receptor agonist nomilin extends lifespan and healthspan in preclinical models through detoxification functions
Shengjie Fan, Yingxuan Yan, Ying Xia, Zhenyu Zhou, Lingling Luo, Mengnan Zhu, Yongli Han, Deqiang Yao, Lijun Zhang, Minglv Fang, Lina Peng, Jing Yu, Ying Liu, Xiaoyan Gao, Huida Guan, Hongli Li, Changhong Wang, Xiaojun Wu, Huanhu Zhu, Yu Cao, Cheng Huang
Nat Commun. 2023; 14: 3368. Published online 2023 Jun 8. doi: 10.1038/s41467-023-39118-9
PMCID:
PMC10250385
AbstractArticlePDF–3.8M
2.
Vitamin D3 promotes longevity in Caenorhabditis elegans
Billy Huggins, Mindy Farris
GeroScience. 2023 Feb; 45(1): 345–358. Published online 2022 Aug 24. doi: 10.1007/s11357-022-00637-w
PMCID:
PMC9886739
AbstractArticlePDF–2.3M
3.
Cannabinoids activate the insulin pathway to modulate mobilization of cholesterol in C. elegans
Bruno Hernandez-Cravero, Sofia Gallino, Jeremy Florman, Cecilia Vranych, Philippe Diaz, Ana Belén Elgoyhen, Mark J. Alkema, Diego de Mendoza
PLoS Genet. 2022 Nov; 18(11): e1010346. Published online 2022 Nov 8. doi: 10.1371/journal.pgen.1010346
PMCID:
PMC9674138
AbstractArticlePDF–2.0M
4.
Meta-Analysis of Caenorhabditis elegans Transcriptomics Implicates Hedgehog-Like Signaling in Host-Microbe Interactions
Alejandra Zárate-Potes, Irtiqa Ali, Margarida Ribeiro Camacho, Hayley Brownless, Alexandre Benedetto
Front Microbiol. 2022; 13: 853629. Published online 2022 May 10. doi: 10.3389/fmicb.2022.853629
PMCID:
PMC9127769
AbstractArticlePDF–4.6M
5.
Remofuscin induces xenobiotic detoxification via a lysosome-to-nucleus signaling pathway to extend the Caenorhabditis elegans lifespan
Miae Oh, Jiah Yeom, Ulrich Schraermeyer, Sylvie Julien-Schraermeyer, Young-Hee Lim
Sci Rep. 2022; 12: 7161. Published online 2022 May 3. doi: 10.1038/s41598-022-11325-2
PMCID:
PMC9064964
AbstractArticlePDF–1.8M
6.
EPIC: Software Toolkit for Elution Profile-Based Inference of Protein Complexes
Lucas ZhongMing Hu, Florian Goebels, June H. Tan, Eric Wolf, Uros Kuzmanov, Cuihong Wan, Sadhna Phanse, Changjiang Xu, Mike Schertzberg, Andrew G. Fraser, Gary D. Bader, Andrew Emili
Nat Methods. Author manuscript; available in PMC 2021 Mar 26.
Published in final edited form as: Nat Methods. 2019 Aug; 16(8): 737–742. Published online 2019 Jul 15. doi: 10.1038/s41592-019-0461-4
PMCID:
PMC7995176
AbstractArticlePDF–1.0M
7.
Identification of A Novel Link between the Intermediate Filament Organizer IFO-1 and Cholesterol Metabolism in the Caenorhabditis elegans Intestine
Richard A. Coch, Florian Geisler, Andrea Annibal, Adam Antebi, Rudolf E. Leube
Int J Mol Sci. 2020 Nov; 21(21): 8219. Published online 2020 Nov 3. doi: 10.3390/ijms21218219
PMCID:
PMC7672635
AbstractArticlePDF–3.3M
8.
Healthspan pathway maps in C. elegans and humans highlight transcription, proliferation/biosynthesis and lipids
Steffen Möller, Nadine Saul, Alan A. Cohen, Rüdiger Köhling, Sina Sender, Hugo Murua Escobar, Christian Junghanss, Francesca Cirulli, Alessandra Berry, Peter Antal, Priit Adler, Jaak Vilo, Michele Boiani, Ludger Jansen, Dirk Repsilber, Hans Jörgen Grabe, Stephan Struckmann, Israel Barrantes, Mohamed Hamed, Brecht Wouters, Liliane Schoofs, Walter Luyten, Georg Fuellen
Aging (Albany NY) 2020 Jul 15; 12(13): 12534–12581. Published online 2020 Jul 7. doi: 10.18632/aging.103514
PMCID:
PMC7377848
AbstractArticlePDF–2.1M
9.
Cholesterol Regulates Innate Immunity via Nuclear Hormone Receptor NHR-8
Benson Otarigho, Alejandro Aballay
iScience. 2020 May 22; 23(5): 101068. Published online 2020 Apr 18. doi: 10.1016/j.isci.2020.101068
Correction in:
iScience. 2021 Nov 19; 24(11): 103361.
PMCID:
PMC7195545
AbstractArticlePDF–4.4M
10.
The transcription factor NHR-8: A new target to increase ivermectin efficacy in nematodes
Cécile Ménez, Mélanie Alberich, Elise Courtot, Fabrice Guegnard, Alexandra Blanchard, Hugo Aguilaniu, Anne Lespine
PLoS Pathog. 2019 Feb; 15(2): e1007598. Published online 2019 Feb 13. doi: 10.1371/journal.ppat.1007598
PMCID:
PMC6391013
AbstractArticlePDF–2.3M
11.
OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes
Woojin Kim, Ryan S. Underwood, Iva Greenwald, Daniel D. Shaye
Genetics. 2018 Oct; 210(2): 445–461. Published online 2018 Aug 17. doi: 10.1534/genetics.118.301307
PMCID:
PMC6216590
AbstractArticlePDF–1.4M
12.
A novel gene-diet pair modulates C. elegans aging
Sonia Verma, Urmila Jagtap, Anita Goyala, Arnab Mukhopadhyay
PLoS Genet. 2018 Aug; 14(8): e1007608. Published online 2018 Aug 20. doi: 10.1371/journal.pgen.1007608
PMCID:
PMC6117094
AbstractArticlePDF–11M
13.
Larval crowding accelerates C. elegans development and reduces lifespan
Andreas H. Ludewig, Clotilde Gimond, Joshua C. Judkins, Staci Thornton, Dania C. Pulido, Robert J. Micikas, Frank Döring, Adam Antebi, Christian Braendle, Frank C. Schroeder
PLoS Genet. 2017 Apr; 13(4): e1006717. Published online 2017 Apr 10. doi: 10.1371/journal.pgen.1006717
PMCID:
PMC5402976
AbstractArticlePDF–5.0M
14.
Nuclear hormone receptors in C. elegans.
Adam Antebi
WormBook. 2006 : 1–13. Published online 2006 Jan 3. doi: 10.1895/wormbook.1.64.1
PMCID:
PMC4781232
AbstractArticle
15.
Transcriptional regulation.
Peter G Okkema, Michael Krause
WormBook. 2005 : 1–40. Published online 2005 Dec 23. doi: 10.1895/wormbook.1.45.1
PMCID:
PMC4781111
AbstractArticle
16.
Pharmacological classes that extend lifespan of Caenorhabditis elegans
Maria Carretero, Rafael L. Gomez-Amaro, Michael Petrascheck
Front Genet. 2015; 6: 77. Published online 2015 Mar 3. doi: 10.3389/fgene.2015.00077
PMCID:
PMC4347486
AbstractArticlePDF–347K
17.
A novel kinase regulates dietary restriction-mediated longevity in Caenorhabditis elegans
Manish Chamoli, Anupama Singh, Yasir Malik, Arnab Mukhopadhyay
Aging Cell. 2014 Aug; 13(4): 641–655. Published online 2014 Mar 21. doi: 10.1111/acel.12218
PMCID:
PMC4326946
AbstractArticlePDF–2.0M
18.
The NHR-8 Nuclear Receptor Regulates Cholesterol and Bile Acid Homeostasis in C. elegans
Daniel B. Magner, Joshua Wollam, Yidong Shen, Caroline Hoppe, Dongling Li, Christian Latza, Veerle Rottiers, Harald Hutter, Adam Antebi
Cell Metab. Author manuscript; available in PMC 2014 Aug 6.
Published in final edited form as: Cell Metab. 2013 Aug 6; 18(2): 212–224. doi: 10.1016/j.cmet.2013.07.007
PMCID:
PMC3909615
AbstractArticlePDF–4.5M
19.
Extensive Rewiring and Complex Evolutionary Dynamics in a C. elegans Multiparameter Transcription Factor Network
John S. Reece-Hoyes, Carles Pons, Alos Diallo, Akihiro Mori, Shaleen Shrestha, Sreenath Kadreppa, Justin Nelson, Stephanie DiPrima, Amelie Dricot, Bryan R. Lajoie, Philippe Souza Moraes Ribeiro, Matthew T. Weirauch, David E. Hill, Timothy R. Hughes, Chad L. Myers, Albertha J.M. Walhout
Mol Cell. Author manuscript; available in PMC 2013 Oct 10.
Published in final edited form as: Mol Cell. 2013 Jul 11; 51(1): 116–127. Published online 2013 Jun 20. doi: 10.1016/j.molcel.2013.05.018
PMCID:
PMC3794439
AbstractArticlePDF–5.2M
20.
Adaptive and Specialised Transcriptional Responses to Xenobiotic Stress in Caenorhabditis elegans Are Regulated by Nuclear Hormone Receptors
Laura M. Jones, Samantha J. Rayson, Anthony J. Flemming, Peter E. Urwin
PLoS One. 2013; 8(7): e69956. Published online 2013 Jul 26. doi: 10.1371/journal.pone.0069956
PMCID:
PMC3724934
AbstractArticlePDF–4.5M

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