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Items: 1 to 20 of 31

1.
Overexpression of miR-25 Downregulates the Expression of ROBO2 in Idiopathic Intellectual Disability
Rosa María Ordoñez-Razo, Yessica Gutierrez-López, María Antonieta Araujo-Solis, Gloria Benitez-King, Israel Ramírez-Sánchez, Gabriela Galicia
Int J Mol Sci. 2024 Apr; 25(7): 3953. Published online 2024 Apr 2. doi: 10.3390/ijms25073953
PMCID:
PMC11011991
AbstractArticlePDF–3.9M
2.
A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2–Bispecific Antibody for Combination Cancer Therapy
Amr El Zawily, Frederick S. Vizeacoumar, Renuka Dahiya, Sara L. Banerjee, Kalpana K. Bhanumathy, Hussain Elhasasna, Glinton Hanover, Jessica C. Sharpe, Malkon G. Sanchez, Paul Greidanus, R. Greg Stacey, Kyung-Mee Moon, Ilya Alexandrov, Juha P. Himanen, Dimitar B. Nikolov, Humphrey Fonge, Aaron P. White, Leonard J. Foster, Bingcheng Wang, Behzad M. Toosi, Nicolas Bisson, Tajib A. Mirzabekov, Franco J. Vizeacoumar, Andrew Freywald
Clin Cancer Res. 2023 Jul 14; 29(14): 2686–2701. Published online 2023 Mar 28. doi: 10.1158/1078-0432.CCR-22-2535
PMCID:
PMC10345963
AbstractArticlePDF–13M
3.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
4.
Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell
Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low
Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120
PMCID:
PMC10151615
AbstractArticlePDF–2.9M
5.
An ancient founder mutation located between ROBO1 and ROBO2 is responsible for increased microtia risk in Amerindigenous populations
Daniel Quiat, Seong Won Kim, Qi Zhang, Sarah U. Morton, Alexandre C. Pereira, Steven R. DePalma, Jon A. L. Willcox, Barbara McDonough, Daniel M. DeLaughter, Joshua M. Gorham, Justin J. Curran, Melissa Tumblin, Yamileth Nicolau, Maria A. Artunduaga, Lourdes Quintanilla-Dieck, Gabriel Osorno, Luis Serrano, Usama Hamdan, Roland D. Eavey, Christine E. Seidman, J. G. Seidman
Proc Natl Acad Sci U S A. 2022 May 24; 119(21): e2203928119. Published online 2022 May 18. doi: 10.1073/pnas.2203928119
PMCID:
PMC9173816
AbstractArticlePDF–2.6M
6.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
7.
Investigation of DNA variants specific to ROBO2 Isoform ‘a’ in Irish vesicoureteric reflux patients reveals marked CpG island variation
John M. Darlow, Mark G. Dobson, Andrew J. Green, Prem Puri, David E. Barton
Sci Rep. 2020; 10: 2265. Published online 2020 Feb 10. doi: 10.1038/s41598-020-58818-6
PMCID:
PMC7010700
AbstractArticlePDF–1.1M
8.
Roundabout signaling pathway involved in the pathogenesis of COPD by integrative bioinformatics analysis
Yuan-Zhen Lin, Xiao-Ning Zhong, Xin Chen, Yi Liang, Hui Zhang, Dong-Lan Zhu
Int J Chron Obstruct Pulmon Dis. 2019; 14: 2145–2162. Published online 2019 Sep 18. doi: 10.2147/COPD.S216050
PMCID:
PMC6756575
AbstractArticlePDF–9.3M
9.
Oncogenic functions of protein kinase D2 and D3 in regulating multiple cancer‐related pathways in breast cancer
Yan Liu, Jian Li, Zhifang Ma, Jun Zhang, Yuzhi Wang, Zhenghong Yu, Xue Lin, Zhi Xu, Qian Su, Li An, Yehui Zhou, Xinxing Ma, Yiwen Yang, Feifei Wang, Qingfei Chen, Yunchao Zhang, Jilinlin Wang, Huilin Zheng, Aihua Shi, Shuang Yu, Jingzhong Zhang, Weiyong Zhao, Liming Chen
Cancer Med. 2019 Feb; 8(2): 729–741. Published online 2019 Jan 16. doi: 10.1002/cam4.1938
PMCID:
PMC6504119
AbstractArticlePDF–1.3M
10.
Robo2 contains a cryptic binding site for neural EGFL-like (NELL) protein 1/2
Naoka Yamamoto, Manabu Kashiwagi, Manami Ishihara, Takaaki Kojima, Andrés D. Maturana, Shun'ichi Kuroda, Tomoaki Niimi
J Biol Chem. 2019 Mar 22; 294(12): 4693–4703. Published online 2019 Jan 30. doi: 10.1074/jbc.RA118.005819
PMCID:
PMC6433047
AbstractArticlePDF–1.6M
11.
A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway
Emmy Van Quickelberghe, Delphine De Sutter, Geert van Loo, Sven Eyckerman, Kris Gevaert
Sci Data. 2018; 5: 180289. Published online 2018 Dec 18. doi: 10.1038/sdata.2018.289
PMCID:
PMC6298254
AbstractArticlePDF–1.4M
12.
Human placental multipotent mesenchymal stromal cells modulate placenta angiogenesis through Slit2-Robo signaling
Cheng-Yi Chen, Chin-Han Tsai, Chia-Yu Chen, Yi-Hsin Wu, Chie-Pein Chen
Cell Adh Migr. 2016 Jan-Apr; 10(1-2): 66–76. Published online 2016 Jan 8. doi: 10.1080/19336918.2015.1108510
PMCID:
PMC4853036
AbstractArticlePDF–736K
13.
Whole-exome and targeted sequencing identify ROBO1 and ROBO2 mutations as progression-related drivers in myelodysplastic syndromes
Feng Xu, Ling-Yun Wu, Chun-Kang Chang, Qi He, Zheng Zhang, Li Liu, Wen-Hui Shi, Juan Guo, Yang Zhu, You-Shan Zhao, Shu-Cheng Gu, Cheng-Ming Fei, Dong Wu, Li-Yu Zhou, Ji-Ying Su, Lu-Xi Song, Chao Xiao, Xiao Li
Nat Commun. 2015; 6: 8806. Published online 2015 Nov 26. doi: 10.1038/ncomms9806
PMCID:
PMC4674765
AbstractArticlePDF–1.8M
14.
Mutations of the SLIT2-ROBO2 pathway genes SLIT2 and SRGAP1 Confer Risk for Congenital Anomalies of the Kidney and Urinary Tract
Daw-Yang Hwang, Stefan Kohl, Xueping Fan, Asaf Vivante, Stefanie Chan, Gabriel C Dworschak, Julian Schulz, Albertien M van Eerde, Alina C Hilger, Heon Yung Gee, Tracie Pennimpede, Bernhard G Herrmann, Glenn van de Hoek, Kirsten Y Renkema, Christoph Schell, Tobias B Huber, Heiko M Reutter, Neveen A Soliman, Natasa Stajic, Radovan Bogdanovic, Elijah O Kehinde, Richard P Lifton, Velibor Tasic, Weining Lu, Friedhelm Hildebrandt
Hum Genet. Author manuscript; available in PMC 2016 Aug 1.
Published in final edited form as: Hum Genet. 2015 Aug; 134(8): 905–916. Published online 2015 May 31. doi: 10.1007/s00439-015-1570-5
PMCID:
PMC4497857
AbstractArticlePDF–2.5M
15.
Common variation near ROBO2 is associated with expressive vocabulary in infancy
Beate St Pourcain, Rolieke A.M. Cents, Andrew J.O. Whitehouse, Claire M.A. Haworth, Oliver S.P. Davis, Paul F. O’Reilly, Susan Roulstone, Yvonne Wren, Qi W. Ang, Fleur P. Velders, David M. Evans, John P. Kemp, Nicole M. Warrington, Laura Miller, Nicholas J. Timpson, Susan M. Ring, Frank C. Verhulst, Albert Hofman, Fernando Rivadeneira, Emma L. Meaburn, Thomas S. Price, Philip S. Dale, Demetris Pillas, Anneli Yliherva, Alina Rodriguez, Jean Golding, Vincent W.V. Jaddoe, Marjo-Riitta Jarvelin, Robert Plomin, Craig E. Pennell, Henning Tiemeier, George Davey Smith
Nat Commun. 2014 Sep 16; 5: 4831. Published online 2014 Sep 16. doi: 10.1038/ncomms5831
PMCID:
PMC4175587
AbstractArticlePDF–686K
16.
Down-regulation of ROBO2 Expression in Prostate Cancers
Youn Jin Choi, Nam Jin Yoo, Sug Hyung Lee
Pathol Oncol Res. 2014; 20(3): 517–519. Published online 2013 Nov 24. doi: 10.1007/s12253-013-9722-1
PMCID:
PMC4062814
AbstractArticlePDF–393K
17.
Genetic variants associated with disordered eating
Tracey D Wade, Scott Gordon, Sarah Medland, Cynthia M. Bulik, Andrew C Heath, Grant W Montgomery, Nicholas G Martin
Int J Eat Disord. Author manuscript; available in PMC 2014 Sep 1.
Published in final edited form as: Int J Eat Disord. 2013 Sep; 46(6): 594–608. Published online 2013 Apr 9. doi: 10.1002/eat.22133
PMCID:
PMC3775874
AbstractArticlePDF–2.1M
18.
Loci Associated with N-Glycosylation of Human Immunoglobulin G Show Pleiotropy with Autoimmune Diseases and Haematological Cancers
Gordan Lauc, Jennifer E. Huffman, Maja Pučić, Lina Zgaga, Barbara Adamczyk, Ana Mužinić, Mislav Novokmet, Ozren Polašek, Olga Gornik, Jasminka Krištić, Toma Keser, Veronique Vitart, Blanca Scheijen, Hae-Won Uh, Mariam Molokhia, Alan Leslie Patrick, Paul McKeigue, Ivana Kolčić, Ivan Krešimir Lukić, Olivia Swann, Frank N. van Leeuwen, L. Renee Ruhaak, Jeanine J. Houwing-Duistermaat, P. Eline Slagboom, Marian Beekman, Anton J. M. de Craen, André M. Deelder, Qiang Zeng, Wei Wang, Nicholas D. Hastie, Ulf Gyllensten, James F. Wilson, Manfred Wuhrer, Alan F. Wright, Pauline M. Rudd, Caroline Hayward, Yurii Aulchenko, Harry Campbell, Igor Rudan
PLoS Genet. 2013 Jan; 9(1): e1003225. Published online 2013 Jan 31. doi: 10.1371/journal.pgen.1003225
PMCID:
PMC3561084
AbstractArticlePDF–1.0M
19.
Inactivation of SLIT2-ROBO1/2 Pathway in Premalignant Lesions of Uterine Cervix: Clinical and Prognostic Significances
Sraboni Mitra, Dipanjana Mazumder-Indra, Ranajit K. Mondal, Partha S. Basu, Anup Roy, Susanta Roychoudhury, Chinmay K. Panda
PLoS One. 2012; 7(6): e38342. Published online 2012 Jun 13. doi: 10.1371/journal.pone.0038342
PMCID:
PMC3374764
AbstractArticlePDF–2.3M
20.
Genome-Wide Association Study of Circulating Estradiol, Testosterone, and Sex Hormone-Binding Globulin in Postmenopausal Women
Jennifer Prescott, Deborah J. Thompson, Peter Kraft, Stephen J. Chanock, Tina Audley, Judith Brown, Jean Leyland, Elizabeth Folkerd, Deborah Doody, Susan E. Hankinson, David J. Hunter, Kevin B. Jacobs, Mitch Dowsett, David G. Cox, Douglas F. Easton, Immaculata De Vivo
PLoS One. 2012; 7(6): e37815. Published online 2012 Jun 4. doi: 10.1371/journal.pone.0037815
PMCID:
PMC3366971
AbstractArticlePDF–138K

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