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Select item 107988581.

Fast-evolving cofactors regulate the role of HEATR5 complexes in intra-Golgi trafficking

Lucas J. Marmorale, Huan Jin, Thomas G. Reidy, Brandon Palomino-Alonso, Christopher J. Zysnarski, Fatima Jordan-Javed, Sagar Lahiri, Mara C. Duncan

J Cell Biol. 2024 Mar 4; 223(3): e202309047. Published online 2024 Jan 19. doi: 10.1083/jcb.202309047

PMCID:: PMC10798858

Abstract Article PDF–6.4M

Select item 107001382.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 106476993.

A Protein–Protein Interaction Analysis Suggests a Wide Range of New Functions for the p21-Activated Kinase (PAK) Ste20

Ifeoluwapo Matthew Joshua, Meng Lin, Ariestia Mardjuki, Alessandra Mazzola, Thomas Höfken

Int J Mol Sci. 2023 Nov; 24(21): 15916. Published online 2023 Nov 2. doi: 10.3390/ijms242115916

PMCID:: PMC10647699

Abstract Article PDF–5.4M

Select item 102922104.

Nuclear pore complexes mediate subtelomeric gene silencing by regulating PCNA levels on chromatin

Sanjeev Kumar Choudhry, Maxwell L. Neal, Song Li, Arti T. Navare, Trevor Van Eeuwen, Richard W. Wozniak, Fred D. Mast, Michael P. Rout, John D. Aitchison

J Cell Biol. 2023 Sep 4; 222(9): e202207060. Published online 2023 Jun 26. doi: 10.1083/jcb.202207060

PMCID:: PMC10292210

Abstract Article PDF–5.9M

Select item 102350865.

Rio1 downregulates centromeric RNA levels to promote the timely assembly of structurally fit kinetochores

Ksenia Smurova, Michela Damizia, Carmela Irene, Stefania Stancari, Giovanna Berto, Giulia Perticari, Maria Giuseppina Iacovella, Ilaria D’Ambrosio, Maria Giubettini, Réginald Philippe, Chiara Baggio, Elisabetta Callegaro, Andrea Casagranda, Alessandro Corsini, Vincenzo Gentile Polese, Anna Ricci, Erik Dassi, Peter De Wulf

Nat Commun. 2023; 14: 3172. Published online 2023 Jun 1. doi: 10.1038/s41467-023-38920-9

PMCID:: PMC10235086

Abstract Article PDF–2.6M

Select item 102333686.

A systematic proximity ligation approach to studying protein‐substrate specificity identifies the substrate spectrum of the Ssh1 translocon

Nir Cohen, Naama Aviram, Maya Schuldiner

EMBO J. 2023 Jun; 42(11): e113385. Published online 2023 Apr 19. doi: 10.15252/embj.2022113385

PMCID:: PMC10233368

Abstract Article PDF–1.2M

Select item 98363487.

A synthetic genetic array screen for interactions with the RNA helicase DED1 during cell stress in budding yeast

Sara B Carey, Hannah M List, Ashwin Siby, Paolo Guerra, Timothy A Bolger

G3 (Bethesda) 2023 Jan; 13(1): jkac296. Published online 2022 Nov 21. doi: 10.1093/g3journal/jkac296

PMCID:: PMC9836348

Abstract Article PDF–857K

Select item 96380288.

Yeast Smy2 and its human homologs GIGYF1 and -2 regulate Cdc48/VCP function during transcription stress

Michelle Harreman Lehner, Jane Walker, Kotryna Temcinaite, Anna Herlihy, Michael Taschner, Adam C. Berger, Anita H. Corbett, A. Barbara Dirac Svejstrup, Jesper Q. Svejstrup

Cell Rep. 2022 Oct 25; 41(4): 111536. Published online 2022 Oct 25. doi: 10.1016/j.celrep.2022.111536

PMCID:: PMC9638028

Abstract Article

Select item 96309869.

A balancing act: interactions within NuA4/TIP60 regulate picNuA4 function in Saccharomyces cerevisiae and humans

Phoebe Y T Lu, Alyssa C Kirlin, Maria J Aristizabal, Hilary T Brewis, Nancy Lévesque, Dheva T Setiaputra, Nikita Avvakumov, Joris J Benschop, Marian Groot Koerkamp, Frank C P Holstege, Nevan J Krogan, Calvin K Yip, Jacques Côté, Michael S Kobor

Genetics. 2022 Nov; 222(3): iyac136. Published online 2022 Sep 6. doi: 10.1093/genetics/iyac136

PMCID:: PMC9630986

Abstract Article PDF–2.2M

Select item 920981110.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 858383311.

A Multi-Perspective Proximity View on the Dynamic Head Region of the Ribosomal 40S Subunit

Kerstin Schmitt, Alina-Andrea Kraft, Oliver Valerius

Int J Mol Sci. 2021 Nov; 22(21): 11653. Published online 2021 Oct 28. doi: 10.3390/ijms222111653

PMCID:: PMC8583833

Abstract Article PDF–4.2M

Select item 842120412.

Investigation of RNA metabolism through large-scale genetic interaction profiling in yeast

Laurence Decourty, Christophe Malabat, Emmanuel Frachon, Alain Jacquier, Cosmin Saveanu

Nucleic Acids Res. 2021 Sep 7; 49(15): 8535–8555. Published online 2021 Aug 6. doi: 10.1093/nar/gkab680

PMCID:: PMC8421204

Abstract Article PDF–2.9M

Select item 809411713.

SUMOylation stabilizes sister kinetochore biorientation to allow timely anaphase

Xue Bessie Su, Menglu Wang, Claudia Schaffner, Olga O. Nerusheva, Dean Clift, Christos Spanos, David A. Kelly, Michael Tatham, Andreas Wallek, Yehui Wu, Juri Rappsilber, A. Arockia Jeyaprakash, Zuzana Storchova, Ronald T. Hay, Adèle L. Marston

J Cell Biol. 2021 Jul 5; 220(7): e202005130. Published online 2021 Apr 30. doi: 10.1083/jcb.202005130

PMCID:: PMC8094117

Abstract Article PDF–8.1M

Select item 802756714.

Deubiquitinase Ubp3 enhances the proteasomal degradation of key enzymes in sterol homeostasis

Qiuyan Lan, Yanchang Li, Fuqiang Wang, Zhaodi Li, Yuan Gao, Hui Lu, Yihao Wang, Zhenwen Zhao, Zixin Deng, Fuchu He, Junzhu Wu, Ping Xu

J Biol Chem. 2021 Jan-Jun; 296: 100348. Published online 2021 Jan 29. doi: 10.1016/j.jbc.2021.100348

PMCID:: PMC8027567

Abstract Article PDF–3.5M

Select item 794775515.

Suboptimal Global Transcriptional Response Increases the Harmful Effects of Loss-of-Function Mutations

Károly Kovács, Zoltán Farkas, Djordje Bajić, Dorottya Kalapis, Andreea Daraba, Karola Almási, Bálint Kintses, Zoltán Bódi, Richard A Notebaart, Juan F Poyatos, Patrick Kemmeren, Frank C P Holstege, Csaba Pál, Balázs Papp

Mol Biol Evol. 2021 Mar; 38(3): 1137–1150. Published online 2020 Nov 3. doi: 10.1093/molbev/msaa280

PMCID:: PMC7947755

Abstract Article PDF–727K

Select item 790022316.

The ubiquitination-deubiquitination cycle on the ribosomal protein eS7A is crucial for efficient translation

Yuka Takehara, Hideki Yashiroda, Yoshitaka Matsuo, Xian Zhao, Akane Kamigaki, Tetsuo Matsuzaki, Hidetaka Kosako, Toshifumi Inada, Shigeo Murata

iScience. 2021 Mar 19; 24(3): 102145. Published online 2021 Feb 5. doi: 10.1016/j.isci.2021.102145

PMCID:: PMC7900223

Abstract Article PDF–4.5M

Select item 775888017.

Purified Smc5/6 Complex Exhibits DNA Substrate Recognition and Compaction

Pilar Gutierrez-Escribano, Silvia Hormeño, Julene Madariaga-Marcos, Roger Solé-Soler, Francis J. O’Reilly, Kyle Morris, Clara Aicart-Ramos, Ricardo Aramayo, Alex Montoya, Holger Kramer, Juri Rappsilber, Jordi Torres-Rosell, Fernando Moreno-Herrero, Luis Aragon

Mol Cell. 2020 Dec 17; 80(6): 1039–1054.e6. doi: 10.1016/j.molcel.2020.11.012

PMCID:: PMC7758880

Abstract Article

Select item 771875118.

Comprehensive Synthetic Genetic Array Analysis of Alleles That Interact with Mutation of the Saccharomyces cerevisiae RecQ Helicases Hrq1 and Sgs1

Elsbeth Sanders, Phoebe A. Nguyen, Cody M. Rogers, Matthew L. Bochman

G3 (Bethesda) 2020 Dec; 10(12): 4359–4368. Published online 2020 Oct 28. doi: 10.1534/g3.120.401709

PMCID:: PMC7718751

Abstract Article PDF–1.2M

Select item 771184219.

The Ubp3/Bre5 deubiquitylation complex modulates COPII vesicle formation

Natalia Gomez‐Navarro, Jérôme Boulanger, Elizabeth A. Miller

Traffic. 2020 Nov; 21(11): 702–711. Published online 2020 Oct 20. doi: 10.1111/tra.12766

PMCID:: PMC7711842

Abstract Article PDF–7.2M

Select item 770806320.

The catalytic activity of the translation termination factor methyltransferase Mtq2-Trm112 complex is required for large ribosomal subunit biogenesis

Caroline Lacoux, Ludivine Wacheul, Kritika Saraf, Nicolas Pythoud, Emmeline Huvelle, Sabine Figaro, Marc Graille, Christine Carapito, Denis L J Lafontaine, Valérie Heurgué-Hamard

Nucleic Acids Res. 2020 Dec 2; 48(21): 12310–12325. Published online 2020 Nov 9. doi: 10.1093/nar/gkaa972