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Select item 112538841.

Uncovering the Role of the Yeast Lysine Acetyltransferase NuA4 in the Regulation of Nuclear Shape and Lipid Metabolism

Sarah Jane Laframboise, Lauren F. Deneault, Alix Denoncourt, Michael Downey, Kristin Baetz

Mol Cell Biol. 2024; 44(7): 273–288. Published online 2024 Jul 4. doi: 10.1080/10985549.2024.2366206

PMCID:: PMC11253884

Abstract Article PDF–3.2M

Select item 107001382.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 102333683.

A systematic proximity ligation approach to studying protein‐substrate specificity identifies the substrate spectrum of the Ssh1 translocon

Nir Cohen, Naama Aviram, Maya Schuldiner

EMBO J. 2023 Jun; 42(11): e113385. Published online 2023 Apr 19. doi: 10.15252/embj.2022113385

PMCID:: PMC10233368

Abstract Article PDF–1.2M

Select item 101645694.

Differential requirements for Gcn5 and NuA4 HAT activities in the starvation-induced versus basal transcriptomes

Qiaoyun Zheng, Hongfang Qiu, Hongen Zhang, Alan G Hinnebusch

Nucleic Acids Res. 2023 May 8; 51(8): 3696–3721. Published online 2023 Mar 2. doi: 10.1093/nar/gkad099

PMCID:: PMC10164569

Abstract Article PDF–6.9M

Select item 98602545.

Structure of the NuA4 histone acetyltransferase complex

Liting Ji, Lixia Zhao, Ke Xu, Huihan Gao, Yang Zhou, Roger D. Kornberg, Heqiao Zhang

Proc Natl Acad Sci U S A. 2022 Nov 29; 119(48): e2214313119. Published online 2022 Nov 22. doi: 10.1073/pnas.2214313119

PMCID:: PMC9860254

Abstract Article PDF–3.6M

Select item 96430086.

Structure and flexibility of the yeast NuA4 histone acetyltransferase complex

Stefan A Zukin, Matthew R Marunde, Irina K Popova, Katarzyna M Soczek, Eva Nogales, Avinash B Patel

eLife. 2022; 11: e81400. Published online 2022 Oct 20. doi: 10.7554/eLife.81400

PMCID:: PMC9643008

Abstract Article PDF–12M

Select item 96380287.

Yeast Smy2 and its human homologs GIGYF1 and -2 regulate Cdc48/VCP function during transcription stress

Michelle Harreman Lehner, Jane Walker, Kotryna Temcinaite, Anna Herlihy, Michael Taschner, Adam C. Berger, Anita H. Corbett, A. Barbara Dirac Svejstrup, Jesper Q. Svejstrup

Cell Rep. 2022 Oct 25; 41(4): 111536. Published online 2022 Oct 25. doi: 10.1016/j.celrep.2022.111536

PMCID:: PMC9638028

Abstract Article

Select item 96309868.

A balancing act: interactions within NuA4/TIP60 regulate picNuA4 function in Saccharomyces cerevisiae and humans

Phoebe Y T Lu, Alyssa C Kirlin, Maria J Aristizabal, Hilary T Brewis, Nancy Lévesque, Dheva T Setiaputra, Nikita Avvakumov, Joris J Benschop, Marian Groot Koerkamp, Frank C P Holstege, Nevan J Krogan, Calvin K Yip, Jacques Côté, Michael S Kobor

Genetics. 2022 Nov; 222(3): iyac136. Published online 2022 Sep 6. doi: 10.1093/genetics/iyac136

PMCID:: PMC9630986

Abstract Article PDF–2.2M

Select item 93392849.

Fine-tuning acetyl-CoA carboxylase 1 activity through localization: functional genomics reveals a role for the lysine acetyltransferase NuA4 and sphingolipid metabolism in regulating Acc1 activity and localization

Trang Pham, Elizabeth Walden, Sylvain Huard, John Pezacki, Morgan D Fullerton, Kristin Baetz

Genetics. 2022 Aug; 221(4): iyac086. Published online 2022 May 24. doi: 10.1093/genetics/iyac086

PMCID:: PMC9339284

Abstract Article PDF–1.6M

Select item 928602310.

Mediator recruits the cohesin loader Scc2 to RNA Pol II-transcribed genes and promotes sister chromatid cohesion

Mark Mattingly, Chris Seidel, Sofía Muñoz, Yan Hao, Ying Zhang, Zhihui Wen, Laurence Florens, Frank Uhlmann, Jennifer L. Gerton

Curr Biol. 2022 Jul 11; 32(13): 2884–2896.e6. doi: 10.1016/j.cub.2022.05.019

PMCID:: PMC9286023

Abstract Article

Select item 920981111.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 828479912.

NuA4 and SAGA acetyltransferase complexes cooperate for repair of DNA breaks by homologous recombination

Xue Cheng, Valérie Côté, Jacques Côté

PLoS Genet. 2021 Jul; 17(7): e1009459. Published online 2021 Jul 6. doi: 10.1371/journal.pgen.1009459

PMCID:: PMC8284799

Abstract Article PDF–2.1M

Select item 772838713.

Phenomic screen identifies a role for the yeast lysine acetyltransferase NuA4 in the control of Bcy1 subcellular localization, glycogen biosynthesis, and mitochondrial morphology

Elizabeth A. Walden, Roger Y. Fong, Trang T. Pham, Hana Knill, Sarah Jane Laframboise, Sylvain Huard, Mary-Ellen Harper, Kristin Baetz

PLoS Genet. 2020 Nov; 16(11): e1009220. Published online 2020 Nov 30. doi: 10.1371/journal.pgen.1009220

PMCID:: PMC7728387

Abstract Article PDF–4.0M

Select item 751569414.

RNA-binding and prion domains: the Yin and Yang of phase separation

Nieves Lorenzo Gotor, Alexandros Armaos, Giulia Calloni, Marc Torrent Burgas, R Martin Vabulas, Natalia Sanchez De Groot, Gian Gaetano Tartaglia

Nucleic Acids Res. 2020 Sep 25; 48(17): 9491–9504. Published online 2020 Aug 28. doi: 10.1093/nar/gkaa681

PMCID:: PMC7515694

Abstract Article PDF–3.1M

Select item 727317715.

Chaperone-Mediated Protein Disaggregation Triggers Proteolytic Clearance of Intra-nuclear Protein Inclusions

Fabian den Brave, Lucas V. Cairo, Chandhuru Jagadeesan, Carmen Ruger-Herreros, Axel Mogk, Bernd Bukau, Stefan Jentsch

Cell Rep. 2020 Jun 2; 31(9): 107680. Published online 2020 Jun 2. doi: 10.1016/j.celrep.2020.107680

PMCID:: PMC7273177

Abstract Article

Select item 704996216.

Intracellular vesicle clusters are organelles that synthesize extracellular vesicle–associated cargo proteins in yeast

Chelsea M. Winters, Ly Q. Hong-Brown, Hui-Ling Chiang

J Biol Chem. 2020 Feb 28; 295(9): 2650–2663. Published online 2020 Jan 23. doi: 10.1074/jbc.RA119.008612

PMCID:: PMC7049962

Abstract Article PDF–1.3M

Select item 666992217.

Endosome and Golgi‐associated degradation (EGAD) of membrane proteins regulates sphingolipid metabolism

Oliver Schmidt, Yannick Weyer, Verena Baumann, Michael A Widerin, Sebastian Eising, Mihaela Angelova, Alexander Schleiffer, Leopold Kremser, Herbert Lindner, Matthias Peter, Florian Fröhlich, David Teis

EMBO J. 2019 Aug 1; 38(15): e101433. Published online 2019 May 27. doi: 10.15252/embj.2018101433

PMCID:: PMC6669922

Abstract Article PDF–2.8M

Select item 644418618.

A Lipid Transfer Protein Signaling Axis Exerts Dual Control of Cell-Cycle and Membrane Trafficking Systems

Jin Huang, Carl J. Mousley, Louis Dacquay, Nairita Maitra, Guillaume Drin, Chong He, Neale D. Ridgway, Ashutosh Tripathi, Michael Kennedy, Brian K. Kennedy, Wenshe Liu, Kristin Baetz, Michael Polymenis, Vytas A. Bankaitis

Dev Cell. Author manuscript; available in PMC 2019 Apr 2.

Published in final edited form as: Dev Cell. 2018 Feb 5; 44(3): 378–391.e5. Published online 2018 Jan 27. doi: 10.1016/j.devcel.2017.12.026

PMCID:: PMC6444186

Abstract Article PDF–1.9M

Select item 631248419.

NuA4 acetyltransferase is required for efficient nucleotide excision repair in yeast

Amelia J. Hodges, Dalton A. Plummer, John J. Wyrick

DNA Repair (Amst) Author manuscript; available in PMC 2020 Jan 1.

Published in final edited form as: DNA Repair (Amst). 2019 Jan; 73: 91–98. Published online 2018 Nov 14. doi: 10.1016/j.dnarep.2018.11.006

PMCID:: PMC6312484

Abstract Article PDF–1.3M

Select item 617663120.

Phospho-dependent recruitment of the yeast NuA4 acetyltransferase complex by MRX at DNA breaks regulates RPA dynamics during resection

Xue Cheng, Olivier Jobin-Robitaille, Pierre Billon, Rémi Buisson, Hengyao Niu, Nicolas Lacoste, Nebiyu Abshiru, Valérie Côté, Pierre Thibault, Stephen J. Kron, Patrick Sung, Christopher J. Brandl, Jean-Yves Masson, Jacques Côté

Proc Natl Acad Sci U S A. 2018 Oct 2; 115(40): 10028–10033. Published online 2018 Sep 17. doi: 10.1073/pnas.1806513115