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Select item 111788421.

Loss of connectin novex-3 leads to heart dysfunction associated with impaired cardiomyocyte proliferation and abnormal nuclear mechanics

Ken Hashimoto, Momoko Ohira, Aya Kodama, Misaki Kimoto, Mariko Inoue, Shigenobu Toné, Yuu Usui, Akira Hanashima, Takato Goto, Yuhei Ogura, Yoshihiro Ujihara, Satoshi Mohri

Sci Rep. 2024; 14: 13727. Published online 2024 Jun 14. doi: 10.1038/s41598-024-64608-1

PMCID:: PMC11178842

Abstract Article PDF–5.4M

Select item 110681982.

PHF2 regulates sarcomeric gene transcription in myogenesis

Taku Fukushima, Yuka Hasegawa, Sachi Kuse, Taiju Fujioka, Takeshi Nikawa, Satoru Masubuchi, Iori Sakakibara

PLoS One. 2024; 19(5): e0301690. Published online 2024 May 3. doi: 10.1371/journal.pone.0301690

PMCID:: PMC11068198

Abstract Article PDF–2.0M

Select item 109535653.

Cfp1 Controls Cardiomyocyte Maturation by Modifying Histone H3K4me3 of Structural, Metabolic, and Contractile Related Genes

Changzhu Li, Yang Zhang, Jingling Shen, Hairong Bao, Yue Zhao, Desheng Li, Sijia Li, Yining Liu, Jiming Yang, Zhiwen Zhou, Kangyi Gao, Lexin Zhao, Yao Pei, Yanjie Lu, Zhenwei Pan, Benzhi Cai

Adv Sci (Weinh) 2024 Mar; 11(11): 2305992. Published online 2024 Jan 9. doi: 10.1002/advs.202305992

PMCID:: PMC10953565

Abstract Article PDF–5.8M

Select item 108979194.

Coordinated metabolic responses to cyclophilin D deletion in the developing heart

Gisela Beutner, Jonathan Ryan Burris, Michael P. Collins, Chaitanya A. Kulkarni, Sergiy M. Nadtochiy, Karen L. de Mesy Bentley, Ethan D. Cohen, Paul S. Brookes, George A. Porter, Jr.

iScience. 2024 Mar 15; 27(3): 109157. Published online 2024 Feb 9. doi: 10.1016/j.isci.2024.109157

PMCID:: PMC10897919

Abstract Article PDF–5.5M

Select item 108545025.

Investigation into Cardiac Myhc-α 334–352-Specific TCR Transgenic Mice Reveals a Role for Cytotoxic CD4 T Cells in the Development of Cardiac Autoimmunity

Meghna Sur, Mahima T. Rasquinha, Kiruthiga Mone, Chandirasegaran Massilamany, Ninaad Lasrado, Channabasavaiah Gurumurthy, Raymond A. Sobel, Jay Reddy

Cells. 2024 Feb; 13(3): 234. Published online 2024 Jan 26. doi: 10.3390/cells13030234

PMCID:: PMC10854502

Abstract Article PDF–11M

Select item 108477466.

Calcium-binding protein 7 expressed in muscle negatively regulates age-related degeneration of neuromuscular junctions in mice

Takahiro Eguchi, Tohru Tezuka, Yuji Watanabe, Akane Inoue-Yamauchi, Hiroshi Sagara, Manabu Ozawa, Yuji Yamanashi

iScience. 2024 Feb 16; 27(2): 108997. Published online 2024 Jan 26. doi: 10.1016/j.isci.2024.108997

PMCID:: PMC10847746

Abstract Article PDF–5.7M

Select item 105456737.

The CREG1-FBXO27-LAMP2 axis alleviates diabetic cardiomyopathy by promoting autophagy in cardiomyocytes

Dan Liu, Ruinan Xing, Quanyu Zhang, Xiaoxiang Tian, Yanping Qi, Haixu Song, Yanxia Liu, Haibo Yu, Xiaolin Zhang, Quanmin Jing, Chenghui Yan, Yaling Han

Exp Mol Med. 2023 Sep; 55(9): 2025–2038. Published online 2023 Sep 1. doi: 10.1038/s12276-023-01081-2

PMCID:: PMC10545673

Abstract Article PDF–5.6M

Select item 104981468.

FAM122A Is Required for Mesendodermal and Cardiac Differentiation of Embryonic Stem Cells

Yun-Sheng Yang, Man-Hua Liu, Zhao-Wen Yan, Guo-Qiang Chen, Ying Huang

Stem Cells. 2023 Apr; 41(4): 354–367. Published online 2023 Jan 30. doi: 10.1093/stmcls/sxad008

PMCID:: PMC10498146

Abstract Article PDF–29M

Select item 104787539.

Lem2 is essential for cardiac development by maintaining nuclear integrity

Jacob A Ross, Nathaly Arcos-Villacis, Edmund Battey, Cornelis Boogerd, Constanza Avalos Orellana, Emilie Marhuenda, Pamela Swiatlowska, Didier Hodzic, Fabrice Prin, Tim Mohun, Norman Catibog, Olga Tapia, Larry Gerace, Thomas Iskratsch, Ajay M Shah, Matthew J Stroud

Cardiovasc Res. 2023 Aug; 119(11): 2074–2088. Published online 2023 Apr 17. doi: 10.1093/cvr/cvad061

PMCID:: PMC10478753

Abstract Article PDF–33M

Select item 1047427010.

α-myosin heavy chain lactylation maintains sarcomeric structure and function and alleviates the development of heart failure

Naijin Zhang, Ying Zhang, Jiaqi Xu, Pengbo Wang, Boquan Wu, Saien Lu, Xinxin Lu, Shilong You, Xinyue Huang, Mohan Li, Yuanming Zou, Mengke Liu, Yuanhui Zhao, Guozhe Sun, Wenbin Wang, Danxi Geng, Jingwei Liu, Liu Cao, Yingxian Sun

Cell Res. 2023 Sep; 33(9): 679–698. Published online 2023 Jul 13. doi: 10.1038/s41422-023-00844-w

PMCID:: PMC10474270

Abstract Article PDF–14M

Select item 1039049211.

Three-dimensional molecular architecture of mouse organogenesis

Fangfang Qu, Wenjia Li, Jian Xu, Ruifang Zhang, Jincan Ke, Xiaodie Ren, Xiaogao Meng, Lexin Qin, Jingna Zhang, Fangru Lu, Xin Zhou, Xi Luo, Zhen Zhang, Minhan Wang, Guangming Wu, Duanqing Pei, Jiekai Chen, Guizhong Cui, Shengbao Suo, Guangdun Peng

Nat Commun. 2023; 14: 4599. Published online 2023 Jul 31. doi: 10.1038/s41467-023-40155-7

PMCID:: PMC10390492

Abstract Article PDF–13M

Select item 1035677112.

Opposing gene regulatory programs governing myofiber development and maturation revealed at single nucleus resolution

Matthieu Dos Santos, Akansha M. Shah, Yichi Zhang, Svetlana Bezprozvannaya, Kenian Chen, Lin Xu, Weichun Lin, John R. McAnally, Rhonda Bassel-Duby, Ning Liu, Eric N. Olson

Nat Commun. 2023; 14: 4333. Published online 2023 Jul 19. doi: 10.1038/s41467-023-40073-8

PMCID:: PMC10356771

Abstract Article PDF–4.9M

Select item 1033036213.

Polycomb group protein CBX7 represses cardiomyocyte proliferation via modulation of the TARDBP/RBM38 axis

Kyu-Won Cho, Mark Andrade, Seongho Bae, Sangsung Kim, Jin Eyun Kim, Er Yearn Jang, Sangho Lee, Ahsan Husain, Roy L. Sutliff, John W. Calvert, Changwon Park, Young-sup Yoon

Circulation. Author manuscript; available in PMC 2024 Jun 13.

Published in final edited form as: Circulation. 2023 Jun 13; 147(24): 1823–1842. Published online 2023 May 9. doi: 10.1161/CIRCULATIONAHA.122.061131

PMCID:: PMC10330362

Abstract Article PDF–1.6M

Select item 1026668114.

Overlapping functions of SIX homeoproteins during embryonic myogenesis

Maud Wurmser, Rouba Madani, Nathalie Chaverot, Stéphanie Backer, Matthew Borok, Matthieu Dos Santos, Glenda Comai, Shahragim Tajbakhsh, Frédéric Relaix, Marc Santolini, Ramkumar Sambasivan, Rulang Jiang, Pascal Maire

PLoS Genet. 2023 Jun; 19(6): e1010781. Published online 2023 Jun 2. doi: 10.1371/journal.pgen.1010781

PMCID:: PMC10266681

Abstract Article PDF–4.6M

Select item 1002316115.

The long noncoding RNA Charme supervises cardiomyocyte maturation by controlling cell differentiation programs in the developing heart

Valeria Taliani, Giulia Buonaiuto, Fabio Desideri, Adriano Setti, Tiziana Santini, Silvia Galfrè, Leonardo Schirone, Davide Mariani, Giacomo Frati, Valentina Valenti, Sebastiano Sciarretta, Emerald Perlas, Carmine Nicoletti, Antonio Musarò, Monica Ballarino

eLife. 2023; 12: e81360. Published online 2023 Mar 6. doi: 10.7554/eLife.81360

PMCID:: PMC10023161

Abstract Article PDF–4.8M

Select item 1000137216.

Insights into the Role of a Cardiomyopathy-Causing Genetic Variant in ACTN2

Sophie Broadway-Stringer, He Jiang, Kirsty Wadmore, Charlotte Hooper, Gillian Douglas, Violetta Steeples, Amar J. Azad, Evie Singer, Jasmeet S. Reyat, Frantisek Galatik, Elisabeth Ehler, Pauline Bennett, Jacinta I. Kalisch-Smith, Duncan B. Sparrow, Benjamin Davies, Kristina Djinovic-Carugo, Mathias Gautel, Hugh Watkins, Katja Gehmlich

Cells. 2023 Mar; 12(5): 721. Published online 2023 Feb 24. doi: 10.3390/cells12050721

PMCID:: PMC10001372

Abstract Article PDF–2.7M

Select item 991873617.

Intrafusal-fiber LRP4 for muscle spindle formation and maintenance in adult and aged animals

Rangjuan Cao, Peng Chen, Hongsheng Wang, Hongyang Jing, Hongsheng Zhang, Guanglin Xing, Bin Luo, Jinxiu Pan, Zheng Yu, Wen-Cheng Xiong, Lin Mei

Nat Commun. 2023; 14: 744. Published online 2023 Feb 10. doi: 10.1038/s41467-023-36454-8

PMCID:: PMC9918736

Abstract Article PDF–4.0M

Select item 967555618.

DIO3 protects against thyrotoxicosis-derived cranio-encephalic and cardiac congenital abnormalities

M. Elena Martinez, Ilka Pinz, Marilena Preda, Christine R. Norton, Thomas Gridley, Arturo Hernandez

JCI Insight. 2022 Nov 8; 7(21): e161214. Published online 2022 Nov 8. doi: 10.1172/jci.insight.161214

PMCID:: PMC9675556

Abstract Article PDF–3.9M

Select item 956419219.

PGC-1α4 Interacts with REST to Upregulate Neuronal Genes and Augment Energy Consumption in Developing Cardiomyocytes

Tomi Tuomainen, Nikolay Naumenko, Maija Mutikainen, Anastasia Shakirzyanova, Sarah Sczelecki, Jennifer L. Estall, Jorge L. Ruas, Pasi Tavi

Cells. 2022 Oct; 11(19): 2944. Published online 2022 Sep 20. doi: 10.3390/cells11192944

PMCID:: PMC9564192

Abstract Article PDF–3.2M

Select item 955395120.

Neonatal ketone body elevation regulates postnatal heart development by promoting cardiomyocyte mitochondrial maturation and metabolic reprogramming

Danyang Chong, Yayun Gu, Tongyu Zhang, Yu Xu, Dandan Bu, Zhong Chen, Na Xu, Liangkui Li, Xiyu Zhu, Haiquan Wang, Yangqing Li, Feng Zheng, Dongjin Wang, Peng Li, Li Xu, Zhibin Hu, Chaojun Li

Cell Discov. 2022; 8: 106. Published online 2022 Oct 11. doi: 10.1038/s41421-022-00447-6