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Select item 103305461.

Cis-B7:CD28 Interactions at Invaginated Synaptic Membranes Activate CD28 and Promote CD8⁺ T Cell Function and Anti-Tumor Immunity

Yunlong Zhao, Christine Caron, Ya-Yuan Chan, Calvin K. Lee, Xiaozheng Xu, Jibin Zhang, Takeya Masubuchi, Chuan Wu, Jack D. Bui, Enfu Hui

Immunity. Author manuscript; available in PMC 2024 Jun 13.

Published in final edited form as: Immunity. 2023 Jun 13; 56(6): 1187–1203.e12. Published online 2023 May 8. doi: 10.1016/j.immuni.2023.04.005

PMCID:: PMC10330546

Abstract Article PDF–4.1M

Select item 100799572.

Nasopharyngeal carcinoma cells promote regulatory T cell development and suppressive activity via CD70-CD27 interaction

Lanqi Gong, Jie Luo, Yu Zhang, Yuma Yang, Shanshan Li, Xiaona Fang, Baifeng Zhang, Jiao Huang, Larry Ka-Yue Chow, Dittman Chung, Jinlin Huang, Cuicui Huang, Qin Liu, Lu Bai, Yuen Chak Tiu, Pingan Wu, Yan Wang, George Sai-Wah Tsao, Dora Lai-wan Kwong, Anne Wing-Mui Lee, Wei Dai, Xin-Yuan Guan

Nat Commun. 2023; 14: 1912. Published online 2023 Apr 6. doi: 10.1038/s41467-023-37614-6

PMCID:: PMC10079957

Abstract Article PDF–5.3M

Select item 98969653.

Mechanisms of CD40-dependent cDC1 licensing beyond costimulation

Renee Wu, Ray A. Ohara, Suin Jo, Tian-Tian Liu, Stephen T. Ferris, Feiya Ou, Sunkyung Kim, Derek J. Theisen, David A. Anderson, III, Brian W. Wong, Timothy Gershon, Robert D. Schreiber, Theresa L. Murphy, Kenneth M. Murphy

Nat Immunol. Author manuscript; available in PMC 2023 Feb 3.

Published in final edited form as: Nat Immunol. 2022 Nov; 23(11): 1536–1550. Published online 2022 Oct 21. doi: 10.1038/s41590-022-01324-w

PMCID:: PMC9896965

Abstract Article PDF–2.6M

Select item 77873664.

CD70 Inversely Regulates Tregs and iNKT Cells and Modulates Type 1 Diabetes in NOD Mice

Cheng Ye, Benjamin E. Low, Michael V. Wiles, Todd M. Brusko, David V. Serreze, John P. Driver

J Immunol. Author manuscript; available in PMC 2021 Oct 1.

Published in final edited form as: J Immunol. 2020 Oct 1; 205(7): 1763–1777. Published online 2020 Aug 31. doi: 10.4049/jimmunol.2000148

PMCID:: PMC7787366

Abstract Article PDF–1.2M

Select item 65848385.

CD8+ T Cells Protect During Vein Graft Disease Development

Karin H. Simons, Margreet R. de Vries, Hendrika A. B. Peters, J. Wouter Jukema, Paul H. A. Quax, Ramon Arens

Front Cardiovasc Med. 2019; 6: 77. Published online 2019 Jun 13. doi: 10.3389/fcvm.2019.00077

PMCID:: PMC6584838

Abstract Article PDF–4.2M

Select item 58906516.

Gut symbiotic microbes imprint intestinal immune cells with the innate receptor SLAMF4 which contributes to gut immune protection against enteric pathogens

Allison Cabinian, Daniel Sinsimer, May Tang, Youngsoon Jang, Bongkum Choi, Yasmina Laouar, Amale Laouar

Gut. 2018 May; 67(5): 847–859. Published online 2017 Mar 24. doi: 10.1136/gutjnl-2016-313214

PMCID:: PMC5890651

Abstract Article PDF–2.1M

Select item 57615797.

CD70, a novel target of CAR T-cell therapy for gliomas

Linchun Jin, Haitao Ge, Yu Long, Changlin Yang, Yifan (Emily) Chang, Luyan Mu, Elias J Sayour, Gabriel De Leon, Qiong J Wang, James C Yang, Paul S Kubilis, Hongbo Bao, Songsong Xia, Dunyue Lu, Yingjun Kong, Li Hu, Yujiao Shang, Chencheng Jiang, Jing Nie, Shimin Li, Yunhe Gu, Jiahang Sun, Duane A Mitchell, Zhiguo Lin, Jianping Huang

Neuro Oncol. 2018 Jan; 20(1): 55–65. Published online 2017 Jun 23. doi: 10.1093/neuonc/nox116

PMCID:: PMC5761579

Abstract Article PDF–37M

Select item 56873008.

T cell-derived CD70 delivers an immune checkpoint function in inflammatory T cell responses

Rachel E. O'Neill, Wei Du, Hemn Mohammadpour, Emad Alqassim, Jingxin Qiu, George Chen, Philip L. McCarthy, Kelvin P. Lee, Xuefang Cao

J Immunol. Author manuscript; available in PMC 2018 Nov 15.

Published in final edited form as: J Immunol. 2017 Nov 15; 199(10): 3700–3710. Published online 2017 Oct 18. doi: 10.4049/jimmunol.1700380

PMCID:: PMC5687300

Abstract Article PDF–3.3M

Select item 55034799.

Host-derived CD70 suppresses murine GVHD by limiting donor T cell expansion and effector function

Nicholas D. Leigh, Rachel E. O'Neill, Wei Du, Chuan Chen, Jingxin Qiu, Jonathan D. Ashwell, Philip L. McCarthy, George L. Chen, Xuefang Cao

J Immunol. Author manuscript; available in PMC 2018 Jul 1.

Published in final edited form as: J Immunol. 2017 Jul 1; 199(1): 336–347. Published online 2017 May 26. doi: 10.4049/jimmunol.1502181

PMCID:: PMC5503479

Abstract Article PDF–1.0M

Select item 483356110.

CD70 Exacerbates Blood Pressure Elevation and Renal Damage in Response to Repeated Hypertensive Stimuli

Hana A. Itani, Liang Xiao, Mohamed A. Saleh, Jing Wu, Mark A. Pilkinton, Bethany L. Dale, Natalia R. Barbaro, Jason D. Foss, Annet Kirabo, Kim R. Montaniel, Allison E. Norlander, Wei Chen, Ryosuke Sato, L. Gabriel Navar, Simon A. Mallal, Meena S. Madhur, Kenneth E. Bernstein, David G. Harrison

Circ Res. Author manuscript; available in PMC 2017 Apr 15.

Published in final edited form as: Circ Res. 2016 Apr 15; 118(8): 1233–1243. Published online 2016 Mar 17. doi: 10.1161/CIRCRESAHA.115.308111

PMCID:: PMC4833561

Abstract Article PDF–1.7M

Select item 475283111.

CD70 and IFN-1 selectively induce Eomesodermin or T-bet and synergize to promote CD8⁺ T cell responses

Han Dong, Nathan A. Franklin, Shane B. Ritchea, Hideo Yagita, Martin J. Glennie, Timothy N. J. Bullock

Eur J Immunol. Author manuscript; available in PMC 2016 Dec 1.

Published in final edited form as: Eur J Immunol. 2015 Dec; 45(12): 3289–3301. Published online 2015 Nov 6. doi: 10.1002/eji.201445291

PMCID:: PMC4752831

Abstract Article PDF–1.3M

Select item 467430512.

T cells compete by cleaving cell surface CD27 and blocking access to CD70 bearing APCs

Matthew A. Burchill, Beth A. Tamburini, Ross M. Kedl

Eur J Immunol. Author manuscript; available in PMC 2016 Nov 1.

Published in final edited form as: Eur J Immunol. 2015 Nov; 45(11): 3140–3149. Published online 2015 Aug 3. doi: 10.1002/eji.201545749

PMCID:: PMC4674305

Abstract Article PDF–976K

Select item 455856613.

The viral context instructs the redundancy of costimulatory pathways in driving CD8⁺ T cell expansion

Suzanne PM Welten, Anke Redeker, Kees LMC Franken, Jennifer D Oduro, Ferry Ossendorp, Luka Čičin-Šain, Cornelis JM Melief, Peter Aichele, Ramon Arens

eLife. 2015; 4: e07486. Published online 2015 Aug 11. doi: 10.7554/eLife.07486

PMCID:: PMC4558566

Abstract Article PDF–2.0M

Select item 449199514.

Thymus-derived regulatory T cells restrain pro-inflammatory Th1 responses by downregulating CD70 on dendritic cells

Maxime Dhainaut, Caroline Coquerelle, Sophie Uzureau, Julie Denoeud, Valérie Acolty, Guillaume Oldenhove, Adrien Galuppo, Tim Sparwasser, Kris Thielemans, Etienne Pays, Hideo Yagita, Jannie Borst, Muriel Moser

EMBO J. 2015 May 12; 34(10): 1336–1348. Published online 2015 Mar 18. doi: 10.15252/embj.201490312

PMCID:: PMC4491995

Abstract Article PDF–1.4M

Select item 424137415.

Dual function of CD70 in viral infection: modulator of early cytokine responses and activator of adaptive responses

Atef Allam, Melissa Swiecki, William Vermi, Jonathan D. Ashwell, Marco Colonna

J Immunol. Author manuscript; available in PMC 2015 Jul 15.

Published in final edited form as: J Immunol. 2014 Jul 15; 193(2): 871–878. Published online 2014 Jun 9. doi: 10.4049/jimmunol.1302429

Correction in:: J Immunol. 2015 Feb 15; 194(4): 2033.

PMCID:: PMC4241374

Abstract Article PDF–1.0M

Select item 423238416.

Blocking CD27-CD70 costimulatory pathway suppresses experimental colitis

Monika Manocha, Svend Rietdijk, Amale Laouar, Gongxian Liao, Atul Bhan, Jannie Borst, Cox Terhorst, N. Manjunath

J Immunol. Author manuscript; available in PMC 2014 Nov 14.

Published in final edited form as: J Immunol. 2009 Jul 1; 183(1): 270–276. Published online 2009 Jun 12. doi: 10.4049/jimmunol.0802424

Correction in:: volume 183 on page 4135

PMCID:: PMC4232384

Abstract Article PDF–1.0M

Select item 406081017.

Differential Requirement for CD70 and CD80/CD86 in Dendritic Cell-mediated Activation of Tumor Tolerized CD8 T Cells

S. Peter Bak, Mike Stein Barnkob, Ailin Bai, Eileen M. Higham, K. Dane Wittrup, Jianzhu Chen

J Immunol. Author manuscript; available in PMC 2014 Jun 17.

Published in final edited form as: J Immunol. 2012 Aug 15; 189(4): 1708–1716. Published online 2012 Jul 13. doi: 10.4049/jimmunol.1201271

PMCID:: PMC4060810

Abstract Article PDF–2.4M

Select item 386355318.

COMPARISON OF OX40L AND CD70 IN THE PROMOTION OF CD4+ T CELL RESPONSES

Jonathan S. Kurche, Matthew A. Burchill, Phillip J. Sanchez, Catherine Haluszczak, Ross M. Kedl

J Immunol. Author manuscript; available in PMC 2013 Dec 15.

Published in final edited form as: J Immunol. 2010 Aug 15; 185(4): 10.4049/jimmunol.1000172. Published online 2010 Jul 16. doi: 10.4049/jimmunol.1000172

PMCID:: PMC3863553

Abstract Article PDF–3.4M

Select item 375006819.

CD70 is downregulated by interaction with CD27

Mirela Kuka, Ivana Munitic, Maria Letizia Giardino Torchia, Jonathan D. Ashwell

J Immunol. Author manuscript; available in PMC 2014 Sep 1.

Published in final edited form as: J Immunol. 2013 Sep 1; 191(5): 2282–2289. Published online 2013 Aug 2. doi: 10.4049/jimmunol.1300868

PMCID:: PMC3750068

Abstract Article PDF–1.8M

Select item 372510720.

Osteoclast precursors in murine bone marrow express CD27 and are impeded in osteoclast development by CD70 on activated immune cells

Yanling Xiao, Ji-Ying Song, Teun J. de Vries, Christien Fatmawati, Diana B. Parreira, Geerling E. J. Langenbach, Nikolina Bąbała, Martijn A. Nolte, Vincent Everts, Jannie Borst

Proc Natl Acad Sci U S A. 2013 Jul 23; 110(30): 12385–12390. Published online 2013 Jul 5. doi: 10.1073/pnas.1216082110

PMCID:: PMC3725107

Abstract Article PDF–985K

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