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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 108020722.

Inhibition of mitochondrial cyclophilin D, a downstream target of glycogen synthase kinase 3α, improves sperm motility

Seung Hyun Park, Myung Chan Gye

Reprod Biol Endocrinol. 2024; 22: 15. Published online 2024 Jan 22. doi: 10.1186/s12958-024-01186-x

PMCID:: PMC10802072

Abstract Article PDF–4.4M

Select item 107653793.

Dynamic interplay between IL-1 and WNT pathways in regulating dermal adipocyte lineage cells during skin development and wound regeneration

Lixiang Sun, Xiaowei Zhang, Shuai Wu, Youxi Liu, Christian F. Guerrero-Juarez, Wenjie Liu, Jinwen Huang, Qian Yao, Meimei Yin, Jiacheng Li, Raul Ramos, Yanhang Liao, Rundong Wu, Tian Xia, Xinyuan Zhang, Yichun Yang, Fengwu Li, Shujun Heng, Wenlu Zhang, Minggang Yang, Chi-Meng Tzeng, Chao Ji, Maksim V. Plikus, Richard L. Gallo, Ling-juan Zhang

Cell Rep. Author manuscript; available in PMC 2024 Jan 4.

Published in final edited form as: Cell Rep. 2023 Jun 27; 42(6): 112647. Published online 2023 Jun 16. doi: 10.1016/j.celrep.2023.112647

PMCID:: PMC10765379

Abstract Article PDF–6.0M

Select item 102856344.

Toward countering muscle and bone loss with spaceflight: GSK3 as a potential target

Ryan W. Baranowski, Jessica L. Braun, Briana L. Hockey, Jenalyn L. Yumol, Mia S. Geromella, Colton J.F. Watson, Nigel Kurgan, Holt N. Messner, Kennedy C. Whitley, Adam J. MacNeil, Guillemette Gauquelin-Koch, Fabrice Bertile, William Gittings, Rene Vandenboom, Wendy E. Ward, Val A. Fajardo

iScience. 2023 Jul 21; 26(7): 107047. Published online 2023 Jun 8. doi: 10.1016/j.isci.2023.107047

PMCID:: PMC10285634

Abstract Article PDF–3.7M

Select item 97402375.

Investigating the Role of Endothelial Glycogen Synthase Kinase3α/β in Atherogenesis in Low Density Lipoprotein Receptor Knockout Mice

Lauren Mastrogiacomo, Geoff H. Werstuck

Int J Mol Sci. 2022 Dec; 23(23): 14780. Published online 2022 Nov 26. doi: 10.3390/ijms232314780

PMCID:: PMC9740237

Abstract Article PDF–2.3M

Select item 97127766.

GSK3α phosphorylates dynamin-2 to promote GLUT4 endocytosis in muscle cells

Jessica Laiman, Yen-Jung Hsu, Julie Loh, Wei-Chun Tang, Mei-Chun Chuang, Hui-Kang Liu, Wei-Shun Yang, Bi-Chang Chen, Lee-Ming Chuang, Yi-Cheng Chang, Ya-Wen Liu

J Cell Biol. 2023 Feb 6; 222(2): e202102119. Published online 2022 Nov 29. doi: 10.1083/jcb.202102119

PMCID:: PMC9712776

Abstract Article PDF–6.9M

Select item 96643587.

Low-dose lithium supplementation promotes adipose tissue browning and sarco(endo)plasmic reticulum Ca²⁺ ATPase uncoupling in muscle

Mia S. Geromella, Chantal R. Ryan, Jessica L. Braun, Michael S. Finch, Lucas A. Maddalena, Olivia Bagshaw, Briana L. Hockey, Fereshteh Moradi, Rachel K. Fenech, Jisook Ryoo, Daniel M. Marko, Roopan Dhaliwal, Jake Sweezey-Munroe, Sophie I. Hamstra, Georgina Gardner, Sebastian Silvera, Rene Vandenboom, Brian D. Roy, Jeffrey A. Stuart, Rebecca E.K. MacPherson, Val A. Fajardo

J Biol Chem. 2022 Nov; 298(11): 102568. Published online 2022 Oct 7. doi: 10.1016/j.jbc.2022.102568

PMCID:: PMC9664358

Abstract Article PDF–2.7M

Select item 94817118.

Fibroblast GSK-3α Promotes Fibrosis via RAF-MEK-ERK Pathway in the Injured Heart

Prachi Umbarkar, Sultan Tousif, Anand P. Singh, Joshua C. Anderson, Qinkun Zhang, Michelle D. Tallquist, James Woodgett, Hind Lal

Circ Res. Author manuscript; available in PMC 2023 Sep 16.

Published in final edited form as: Circ Res. 2022 Sep 2 : 101161CIRCRESAHA122321431. Published online 2022 Sep 2. doi: 10.1161/CIRCRESAHA.122.321431

PMCID:: PMC9481711

Abstract Article PDF–2.9M

Select item 94093079.

Deletion of Macrophage-Specific Glycogen Synthase Kinase (GSK)-3α Promotes Atherosclerotic Regression in Ldlr^−/− Mice

Sarvatit Patel, Lauren Mastrogiacomo, Madison Fulmer, Yuanyuan Shi, Geoff H. Werstuck

Int J Mol Sci. 2022 Aug; 23(16): 9293. Published online 2022 Aug 18. doi: 10.3390/ijms23169293

PMCID:: PMC9409307

Abstract Article PDF–4.8M

Select item 907632710.

GSK3β Exacerbates Myocardial Ischemia/Reperfusion Injury by Inhibiting Myc

Cong Wen, Meide Lan, Xin Tan, Xiaobo Wang, Zaiyong Zheng, Mingming Lv, Xuemei Zhao, Hao Luo, Yanxu Liu, Ping Wei, Rongchuan Yue, Houxiang Hu, Li Guo

Oxid Med Cell Longev. 2022; 2022: 2588891. Published online 2022 Apr 29. doi: 10.1155/2022/2588891

PMCID:: PMC9076327

Abstract Article PDF–3.7M

Select item 901569911.

The ATG5 interactome links clathrin-mediated vesicular trafficking with the autophagosome assembly machinery

Kiren Baines, Kazuaki Yoshioka, Yoh Takuwa, Jon D. Lane

Autophagy Rep. 2022; 1(1): 88–118. Published online 2022 Apr 7. doi: 10.1080/27694127.2022.2042054

PMCID:: PMC9015699

Abstract Article PDF–3.3M

Select item 883435812.

Isoform-Specific Role of GSK-3 in High Fat Diet Induced Obesity and Glucose Intolerance

Manisha Gupte, Sultan Tousif, Jacob J. Lemon, Angelica Toro Cora, Prachi Umbarkar, Hind Lal

Cells. 2022 Feb; 11(3): 559. Published online 2022 Feb 5. doi: 10.3390/cells11030559

PMCID:: PMC8834358

Abstract Article PDF–2.1M

Select item 878833613.

Isoform- and cell-type specific roles of Glycogen Synthase Kinase 3 N-terminal serine phosphorylation in liver ischemia reperfusion injury

Ming Ni, Haoming Zhou, Jing Zhang, Dan Jin, Tianfei Lu, Ronald W. Busuttil, Jerzy W. Kupiec-Weglinski, Xuehao Wang, Yuan Zhai

J Immunol. Author manuscript; available in PMC 2022 Jan 25.

Published in final edited form as: J Immunol. 2020 Aug 15; 205(4): 1147–1156. Published online 2020 Jul 17. doi: 10.4049/jimmunol.2000397

PMCID:: PMC8788336

Abstract Article PDF–1.5M

Select item 850895014.

Opposing Roles of GSK3α and GSK3β Phosphorylation in Platelet Function and Thrombosis

Samantha F. Moore, Ejaife O. Agbani, Andreas Wersäll, Alastair W. Poole, Chris M. Williams, Xiaojuan Zhao, Yong Li, James L. Hutchinson, Roger W. Hunter, Ingeborg Hers

Int J Mol Sci. 2021 Oct; 22(19): 10656. Published online 2021 Sep 30. doi: 10.3390/ijms221910656

PMCID:: PMC8508950

Abstract Article PDF–3.0M

Select item 850052215.

Glycogen synthase kinase 3 drives thymocyte egress by suppressing β-catenin activation of Akt

Chenfeng Liu, Lei Ma, Yuxuan Wang, Jiayi Zhao, Pengda Chen, Xian Chen, Yingxin Wang, Yanyan Hu, Yun Liu, Xian Jia, Zhanghua Yang, Xingzhi Yin, Jianfeng Wu, Suqin Wu, Haiping Zheng, Xiaohong Ma, Xiufeng Sun, Ying He, Lianghua Lin, Yubing Fu, Kunyu Liao, Xiaojuan Zhou, Shan Jiang, Guofeng Fu, Jian Tang, Wei Han, Xiao Lei Chen, Wenzhu Fan, Yazhen Hong, Jiahuai Han, Xiangyang Huang, Bo-An Li, Nengming Xiao, Changchun Xiao, Guo Fu, Wen-Hsien Liu

Sci Adv. 2021 Oct; 7(41): eabg6262. Published online 2021 Oct 8. doi: 10.1126/sciadv.abg6262

PMCID:: PMC8500522

Abstract Article PDF–4.8M

Select item 849620716.

Glycogen Synthase Kinase 3 Regulates the Genesis of Displaced Retinal Ganglion Cells3

Elena Kisseleff, Robin J. Vigouroux, Catherine Hottin, Sophie Lourdel, Leah Thomas, Parth Shah, Alain Chédotal, Muriel Perron, Anand Swaroop, Jerome E. Roger

eNeuro. 2021 Sep-Oct; 8(5): ENEURO.0171-21.2021. Prepublished online 2021 Sep 13. Published online 2021 Oct 5. doi: 10.1523/ENEURO.0171-21.2021

PMCID:: PMC8496207

Abstract Article PDF–3.9M

Select item 836149417.

Characterizing the Role of Glycogen Synthase Kinase-3α/β in Macrophage Polarization and the Regulation of Pro-Atherogenic Pathways in Cultured Ldlr^-/- Macrophages

Sarvatit Patel, Geoff Werstuck

Front Immunol. 2021; 12: 676752. Published online 2021 Jul 30. doi: 10.3389/fimmu.2021.676752

PMCID:: PMC8361494

Abstract Article PDF–5.3M

Select item 831323918.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 793877019.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 778489120.

GSK3β inhibition restores cortical gamma oscillation and cognitive behavior in a mouse model of NMDA receptor hypofunction relevant to schizophrenia

Kazuhito Nakao, Mahendra Singh, Kiran Sapkota, Bailey C. Hagler, Robert N. Hunter, Chander Raman, John J. Hablitz, Kazu Nakazawa

Neuropsychopharmacology. 2020 Dec; 45(13): 2207–2218. Published online 2020 Aug 28. doi: 10.1038/s41386-020-00819-0

PMCID:: PMC7784891

Abstract Article PDF–1.7M

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