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Select item 107245141.

Rare functional variants in the CRP and G6PC genes modify the relationship between obesity and serum C‐reactive protein in white British population

Xia Li, Alexander Ploner, Yunzhang Wang, Jonathan K. L. Mak, Yi Lu, Patrik K. E. Magnusson, Juulia Jylhävä, Sara Hägg

Mol Genet Genomic Med. 2023 Dec; 11(12): e2255. Published online 2023 Jul 26. doi: 10.1002/mgg3.2255

PMCID:: PMC10724514

Abstract Article PDF–2.2M

Select item 106165062.

G6PC1 and G6PC2 Influence Glucose-6-Phosphate Flux but not 11β-Hydroxysteroid Dehydrogenase Type 1 Activity

Emily M. Hawes, Kayla A. Boortz, James K. Oeser, Margaret L. O’Rourke, Richard M. O’Brien

J Mol Endocrinol. Author manuscript; available in PMC 2024 Nov 1.

Published in final edited form as: J Mol Endocrinol. 2023 Nov 1; 71(4): e230070. Published online 2023 Oct 18. doi: 10.1530/JME-23-0070

PMCID:: PMC10616506

Abstract Article PDF–1005K

Select item 91063033.

Genome-wide CRISPR screens using isogenic cells reveal vulnerabilities conferred by loss of tumor suppressors

Xu Feng, Mengfan Tang, Merve Dede, Dan Su, Guangsheng Pei, Dadi Jiang, Chao Wang, Zhen Chen, Mi Li, Litong Nie, Yun Xiong, Siting Li, Jeong-Min Park, Huimin Zhang, Min Huang, Klaudia Szymonowicz, Zhongming Zhao, Traver Hart, Junjie Chen

Sci Adv. 2022 May; 8(19): eabm6638. Published online 2022 May 13. doi: 10.1126/sciadv.abm6638

PMCID:: PMC9106303

Abstract Article PDF–918K

Select item 89154934.

G6PC indicated poor prognosis in cervical cancer and promoted cervical carcinogenesis in vitro and in vivo

Kun Zhu, Chunling Deng, Pan Du, Taorui Liu, Junjie Piao, Yingshi Piao, Meng Yang, Liyan Chen

Reprod Biol Endocrinol. 2022; 20: 50. Published online 2022 Mar 11. doi: 10.1186/s12958-022-00921-6

PMCID:: PMC8915493

Abstract Article PDF–3.0M

Select item 80584405.

Correction of metabolic abnormalities in a mouse model of glycogen storage disease type Ia by CRISPR/Cas9-based gene editing

Irina Arnaoutova, Lisa Zhang, Hung-Dar Chen, Brian C. Mansfield, Janice Y. Chou

Mol Ther. 2021 Apr 7; 29(4): 1602–1610. Published online 2020 Dec 23. doi: 10.1016/j.ymthe.2020.12.027

PMCID:: PMC8058440

Abstract Article PDF–2.3M

Select item 70147166.

Predominance of the c.648G > T G6PC gene mutation and late complications in Korean patients with glycogen storage disease type Ia

Yoo-Mi Kim, Jin-Ho Choi, Beom-Hee Lee, Gu-Hwan Kim, Kyung-Mo Kim, Han-Wook Yoo

Orphanet J Rare Dis. 2020; 15: 45. Published online 2020 Feb 11. doi: 10.1186/s13023-020-1321-0

PMCID:: PMC7014716

Abstract Article PDF–881K

Select item 63477027.

Failure to eliminate a phosphorylated glucose analog leads to neutropenia in patients with G6PT and G6PC3 deficiency

Maria Veiga-da-Cunha, Nathalie Chevalier, Xavier Stephenne, Jean-Philippe Defour, Nicole Paczia, Alina Ferster, Younes Achouri, Joseph P. Dewulf, Carole L. Linster, Guido T. Bommer, Emile Van Schaftingen

Proc Natl Acad Sci U S A. 2019 Jan 22; 116(4): 1241–1250. Published online 2019 Jan 9. doi: 10.1073/pnas.1816143116

PMCID:: PMC6347702

Abstract Article PDF–1.6M

Select item 54433508.

Crystal structures reveal a new and novel FoxO1 binding site within the human glucose-6-phosphatase catalytic subunit 1 gene promoter

Puja Singh, Eun Hee Han, James A. Endrizzi, Richard M. O’Brien, Young-In Chi

J Struct Biol. Author manuscript; available in PMC 2018 Apr 1.

Published in final edited form as: J Struct Biol. 2017 Apr; 198(1): 54–64. Published online 2017 Feb 20. doi: 10.1016/j.jsb.2017.02.006

PMCID:: PMC5443350

Abstract Article PDF–2.0M

Select item 46405959.

Interaction of ApoA-IV with NR4A1 and NR1D1 Represses G6Pase and PEPCK Transcription: Nuclear Receptor-Mediated Downregulation of Hepatic Gluconeogenesis in Mice and a Human Hepatocyte Cell Line

Xiaoming Li, Min Xu, Fei Wang, Yong Ji, W. Sean DavidsoN, Zongfang Li, Patrick Tso

PLoS One. 2015; 10(11): e0142098. Published online 2015 Nov 10. doi: 10.1371/journal.pone.0142098

PMCID:: PMC4640595

Abstract Article PDF–2.2M

Select item 428901310.

Three novel mutations of the G6PC gene identified in Chinese patients with glycogen storage disease type Ia

Bi-Xia Zheng, Qian Lin, Mei Li, Yu Jin

Eur J Pediatr. 2015; 174(1): 59–63. Published online 2014 Jul 1. doi: 10.1007/s00431-014-2354-y

PMCID:: PMC4289013

Abstract Article PDF–617K

Select item 423317411.

Glucose-6-phosphatase is a Key Metabolic Regulator of Glioblastoma Invasion

Sara Abbadi, Julio J. Rodarte, Ameer Abutaleb, Emily Lavell, Chris L. Smith, William Ruff, Jennifer Schiller, Alessandro Olivi, Andre Levchenko, Hugo Guerrero-Cazares, Alfredo Quinones-Hinojosa

Mol Cancer Res. Author manuscript; available in PMC 2015 Nov 1.

Published in final edited form as: Mol Cancer Res. 2014 Nov; 12(11): 1547–1559. Published online 2014 Jul 7. doi: 10.1158/1541-7786.MCR-14-0106-T

PMCID:: PMC4233174

Abstract Article PDF–2.4M

Select item 371316712.

Toll-like receptor 4 signaling is required for induction of gluconeogenic gene expression by palmitate in human hepatic carcinoma cells

Laman K. Mamedova, Kai Yuan, Amber N. Laudick, Sherry D. Fleming, Douglas G. Mashek, Barry J. Bradford

J Nutr Biochem. Author manuscript; available in PMC 2014 Aug 1.

Published in final edited form as: J Nutr Biochem. 2013 Aug; 24(8): 1499–1507. Published online 2013 Mar 1. doi: 10.1016/j.jnutbio.2012.12.009

PMCID:: PMC3713167

Abstract Article PDF–1.4M

Select item 367391013.

Suppression of Gluconeogenic Gene Expression by LSD1-Mediated Histone Demethylation

Dongning Pan, Chunxiao Mao, Yong-Xu Wang

PLoS One. 2013; 8(6): e66294. Published online 2013 Jun 5. doi: 10.1371/journal.pone.0066294

PMCID:: PMC3673910

Abstract Article PDF–746K

Select item 326170814.

Toward an understanding of the protein interaction network of the human liver

Jian Wang, Keke Huo, Lixin Ma, Liujun Tang, Dong Li, Xiaobi Huang, Yanzhi Yuan, Chunhua Li, Wei Wang, Wei Guan, Hui Chen, Chaozhi Jin, Junchen Wei, Wanqiao Zhang, Yongsheng Yang, Qiongming Liu, Ying Zhou, Cuili Zhang, Zhihao Wu, Wangxiang Xu, Ying Zhang, Tao Liu, Donghui Yu, Yaping Zhang, Liang Chen, Dewu Zhu, Xing Zhong, Lixin Kang, Xiang Gan, Xiaolan Yu, Qi Ma, Jing Yan, Li Zhou, Zhongyang Liu, Yunping Zhu, Tao Zhou, Fuchu He, Xiaoming Yang

Mol Syst Biol. 2011; 7: 536. Published online 2011 Oct 11. doi: 10.1038/msb.2011.67

Correction in:: Mol Syst Biol. 2017 Dec; 13(12): 965.

PMCID:: PMC3261708

Abstract Article PDF–2.0M

Select item 317805915.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 292952416.

Insulin and Epidermal Growth Factor Suppress Basal Glucose-6-Phosphatase Catalytic Subunit Gene Transcription Through Overlapping but Distinct Mechanisms

Hiroshi Onuma, James K. Oeser, Bryce A. Nelson, Yingda Wang, Brian P. Flemming, Lawrence A. Scheving, William E. Russell, Richard M. O’Brien

Biochem J. Author manuscript; available in PMC 2010 Aug 29.

Published in final edited form as: Biochem J. 2009 Jan 15; 417(2): 611–620. doi: 10.1042/BJ20080999

PMCID:: PMC2929524

Abstract Article PDF–2.6M

Select item 270727017.

Fasting hyperglycemia is not associated with increased expression of PEPCK or G6Pc in patients with Type 2 Diabetes

Varman T. Samuel, Sara A. Beddow, Takanori Iwasaki, Xian-Man Zhang, Xin Chu, Christopher D. Still, Glenn S. Gerhard, Gerald I. Shulman

Proc Natl Acad Sci U S A. 2009 Jul 21; 106(29): 12121–12126. Published online 2009 Jul 8. doi: 10.1073/pnas.0812547106

PMCID:: PMC2707270

Abstract Article PDF–388K

Select item 247560018.

Mutations in the Glucose-6-Phosphatase-α (G6PC) Gene that Cause Type Ia Glycogen Storage Disease

Janice Y. Chou, Brian C. Mansfield

Hum Mutat. Author manuscript; available in PMC 2008 Jul 20.

Published in final edited form as: Hum Mutat. 2008 Jul; 29(7): 921–930. doi: 10.1002/humu.20772

PMCID:: PMC2475600

Abstract Article PDF–398K

Select item 180152119.

Genetic Basis of Glycogen Storage Disease Type 1a: Prevalent Mutations at the Glucose-6-Phosphatase Locus

Ke-Jian Lei, Yuan-Tsong Chen, Hungwen Chen, Lee-Jun C. Wong, Ji-Lan Liu, Allyn McConkie-Rosell, Johan L. K. Van Hove, Henry C.-Y. Ou, Nan Jung Yeh, Lorraine Y. Pan, Janice Yang Chou

Am J Hum Genet. 1995 Oct; 57(4): 766–771.

PMCID:: PMC1801521

Summary Page Browse PDF–1.3M

Select item 180127920.

Exon Redefinition by a Point Mutation within Exon 5 of the Glucose-6-Phosphatase Gene is the Major Cause of Glycogen Storage Disease Type 1a in Japan

Susumu Kajihara, Sachiko Matsuhashi, Kyosuke Yamamoto, Keiko Kido, Kazue Tsuji, Ayako Tanae, Shigetoshi Fujiyama, Tadashi Itoh, Keiichiro Tanigawa, Masako Uchida, Yoichi Setoguchi, Mitsuaki Motomura, Toshihiko Mizuta, Takahiro Sakai

Am J Hum Genet. 1995 Sep; 57(3): 549–555.

PMCID:: PMC1801279

Summary Page Browse PDF–1.3M

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