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Items: 1 to 20 of 28

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
3.
Biochemistry of Mitochondrial Coenzyme Q Biosynthesis
Jonathan A. Stefely, David J. Pagliarini
Trends Biochem Sci. Author manuscript; available in PMC 2018 Oct 1.
Published in final edited form as: Trends Biochem Sci. 2017 Oct; 42(10): 824–843. Published online 2017 Sep 17. doi: 10.1016/j.tibs.2017.06.008
PMCID:
PMC5731490
AbstractArticlePDF–1.2M
4.
Mitochondrial function and lifespan of mice with controlled ubiquinone biosynthesis
Ying Wang, Daniella Oxer, Siegfried Hekimi
Nat Commun. Author manuscript; available in PMC 2016 Jan 17.
Published in final edited form as: Nat Commun. 2015 Mar 6; 6: 6393. Published online 2015 Mar 6. doi: 10.1038/ncomms7393
PMCID:
PMC4715896
AbstractArticlePDF–1.8M
5.
Compensatory elevation of voluntary activity in mouse mutants with impaired mitochondrial energy metabolism
Jérôme Lapointe, Bryan G. Hughes, Eve Bigras, Siegfried Hekimi
Physiol Rep. 2014 Nov; 2(11): e12214. Published online 2014 Nov 20. doi: 10.14814/phy2.12214
PMCID:
PMC4255820
AbstractArticlePDF–3.2M
6.
Mitochondrial COQ9 is a lipid-binding protein that associates with COQ7 to enable coenzyme Q biosynthesis
Danielle C. Lohman, Farhad Forouhar, Emily T. Beebe, Matthew S. Stefely, Catherine E. Minogue, Arne Ulbrich, Jonathan A. Stefely, Shravan Sukumar, Marta Luna-Sánchez, Adam Jochem, Scott Lew, Jayaraman Seetharaman, Rong Xiao, Huang Wang, Michael S. Westphall, Russell L. Wrobel, John K. Everett, Julie C. Mitchell, Luis C. López, Joshua J. Coon, Liang Tong, David J. Pagliarini
Proc Natl Acad Sci U S A. 2014 Nov 4; 111(44): E4697–E4705. Published online 2014 Oct 22. doi: 10.1073/pnas.1413128111
PMCID:
PMC4226113
AbstractArticlePDF–1.7M
7.
Life-long protection from global cerebral ischemia and reperfusion in long-lived Mclk1+/− mutants
Huaien Zheng, Jérôme Lapointe, Siegfried Hekimi
Exp Neurol. Author manuscript; available in PMC 2014 Jun 11.
Published in final edited form as: Exp Neurol. 2010 Jun; 223(2): 557–565. Published online 2010 Feb 17. doi: 10.1016/j.expneurol.2010.02.002
PMCID:
PMC4053415
AbstractArticlePDF–1.2M
8.
Mitochondrial respiration without ubiquinone biosynthesis
Ying Wang, Siegfried Hekimi
Hum Mol Genet. 2013 Dec 1; 22(23): 4768–4783. Published online 2013 Jul 11. doi: 10.1093/hmg/ddt330
PMCID:
PMC3888124
AbstractArticlePDF–959K
9.
An Enhanced Immune Response of Mclk1+/− Mutant Mice Is Associated with Partial Protection from Fibrosis, Cancer and the Development of Biomarkers of Aging
Dantong Wang, Ying Wang, Catherine Argyriou, Audrey Carrière, Danielle Malo, Siegfried Hekimi
PLoS One. 2012; 7(11): e49606. Published online 2012 Nov 14. doi: 10.1371/journal.pone.0049606
PMCID:
PMC3498213
AbstractArticlePDF–1.2M
10.
The submitochondrial distribution of ubiquinone affects respiration in long-lived Mclk1+/− mice
Jérôme Lapointe, Ying Wang, Eve Bigras, Siegfried Hekimi
J Cell Biol. 2012 Oct 15; 199(2): 215–224. doi: 10.1083/jcb.201203090
PMCID:
PMC3471228
AbstractArticlePDF–1.9M
11.
Early Mitochondrial Dysfunction in Long-lived Mclk1+/- Mice
Jérôme Lapointe, Siegfried Hekimi
J Biol Chem. 2008 Sep 19; 283(38): 26217–26227. doi: 10.1074/jbc.M803287200
PMCID:
PMC3258865
AbstractArticlePDF–793K
12.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
13.
CALORIE RESTRICTION MODIFIES UBIQUINONE AND COQ TRANSCRIPTS LEVELS IN MOUSE TISSUES
Cristina Parrado, Guillermo López-Lluch, Elisabet Rodríguez-Bies, Sara Santa-Cruz, Plácido Navas, Jon J. Ramsey, José M. Villalba
Free Radic Biol Med. Author manuscript; available in PMC 2012 Jun 15.
Published in final edited form as: Free Radic Biol Med. 2011 Jun 15; 50(12): 1728–1736. Published online 2011 Mar 27. doi: 10.1016/j.freeradbiomed.2011.03.024
PMCID:
PMC3096745
AbstractArticlePDF–529K
14.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
15.
A mitochondrial protein compendium elucidates complex I disease biology
David J. Pagliarini, Sarah E. Calvo, Betty Chang, Sunil A. Sheth, Scott B. Vafai, Shao-En Ong, Geoffrey A. Walford, Canny Sugiana, Avihu Boneh, William K. Chen, David E. Hill, Marc Vidal, James G. Evans, David R. Thorburn, Steven A. Carr, Vamsi K. Mootha
Cell. Author manuscript; available in PMC 2009 Nov 18.
Published in final edited form as: Cell. 2008 Jul 11; 134(1): 112–123. doi: 10.1016/j.cell.2008.06.016
PMCID:
PMC2778844
AbstractArticlePDF–1.2M
16.
Reversal of the Mitochondrial Phenotype and Slow Development of Oxidative Biomarkers of Aging in Long-lived Mclk1+/− Mice
Jérôme Lapointe, Zaruhi Stepanyan, Eve Bigras, Siegfried Hekimi
J Biol Chem. 2009 Jul 24; 284(30): 20364–20374. Published online 2009 May 28. doi: 10.1074/jbc.M109.006569
PMCID:
PMC2740461
AbstractArticlePDF–1.7M
17.
ACCELERATED FAILURE TIME MODELS PROVIDE A USEFUL STATISTICAL FRAMEWORK FOR AGING RESEARCH
William R. Swindell
Exp Gerontol. Author manuscript; available in PMC 2010 Mar 1.
Published in final edited form as: Exp Gerontol. 2009 Mar; 44(3): 190–200. Published online 2008 Oct 25. doi: 10.1016/j.exger.2008.10.005
PMCID:
PMC2718836
AbstractArticlePDF–1.3M
18.
Mclk1+/- mice are not resistant to the development of atherosclerosis
Bryan G Hughes, Siegfried Hekimi
Lipids Health Dis. 2009; 8: 16. Published online 2009 May 5. doi: 10.1186/1476-511X-8-16
PMCID:
PMC2683836
AbstractArticlePDF–1.0M
19.
Identification of transcripts with enriched expression in the developing and adult pancreas
Brad G Hoffman, Bogard Zavaglia, Joy Witzsche, Teresa Ruiz de Algara, Mike Beach, Pamela A Hoodless, Steven JM Jones, Marco A Marra, Cheryl D Helgason
Genome Biol. 2008; 9(6): R99. Published online 2008 Jun 14. doi: 10.1186/gb-2008-9-6-r99
PMCID:
PMC2481431
AbstractArticlePDF–2.2M
20.
BGEM: An In Situ Hybridization Database of Gene Expression in the Embryonic and Adult Mouse Nervous System
Susan Magdaleno, Patricia Jensen, Craig L Brumwell, Anna Seal, Karen Lehman, Andrew Asbury, Tony Cheung, Tommie Cornelius, Diana M Batten, Christopher Eden, Shannon M Norland, Dennis S Rice, Nilesh Dosooye, Sundeep Shakya, Perdeep Mehta, Tom Curran
PLoS Biol. 2006 Apr; 4(4): e86. Published online 2006 Mar 28. doi: 10.1371/journal.pbio.0040086
PMCID:
PMC1413568
ArticlePDF–99K

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