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Select item 111418681.

Lack of SPNS1 results in accumulation of lysolipids and lysosomal storage disease in mouse models

Hoa T.T. Ha, SiYi Liu, Xuan T.A. Nguyen, Linh K. Vo, Nancy C.P. Leong, Dat T. Nguyen, Shivaranjani Balamurugan, Pei Yen Lim, YaJun Wu, Eunju Seong, Toan Q. Nguyen, Jeongah Oh, Markus R. Wenk, Amaury Cazenave-Gassiot, Zuhal Yapici, Wei-Yi Ong, Margit Burmeister, Long N. Nguyen

JCI Insight. 2024 Apr 22; 9(8): e175462. Published online 2024 Mar 7. doi: 10.1172/jci.insight.175462

PMCID:: PMC11141868

Abstract Article PDF–2.8M

Select item 109208352.

Phosphoglycerate mutase 5 aggravates alcoholic liver disease through disrupting VDAC-1-dependent mitochondrial integrity

Tian Xia, Jiachi Yu, Ye Chen, Xing Chang, Miao Meng

Int J Med Sci. 2024; 21(4): 755–764. Published online 2024 Feb 25. doi: 10.7150/ijms.93171

PMCID:: PMC10920835

Abstract Article PDF–3.0M

Select item 109176603.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 108979194.

Coordinated metabolic responses to cyclophilin D deletion in the developing heart

Gisela Beutner, Jonathan Ryan Burris, Michael P. Collins, Chaitanya A. Kulkarni, Sergiy M. Nadtochiy, Karen L. de Mesy Bentley, Ethan D. Cohen, Paul S. Brookes, George A. Porter, Jr.

iScience. 2024 Mar 15; 27(3): 109157. Published online 2024 Feb 9. doi: 10.1016/j.isci.2024.109157

PMCID:: PMC10897919

Abstract Article PDF–5.5M

Select item 107619205.

LncRNA H19 inhibition impairs endoplasmic reticulum-mitochondria contact in hepatic cells and augments gluconeogenesis by increasing VDAC1 levels

Arun Nandwani, Shalu Rathore, Malabika Datta

Redox Biol. 2024 Feb; 69: 102989. Published online 2023 Dec 9. doi: 10.1016/j.redox.2023.102989

PMCID:: PMC10761920

Abstract Article PDF–11M

Select item 107597196.

Identification and validation of voltage‐dependent anion channel 1‐related genes and immune cell infiltration in diabetic nephropathy

Jiaqun Lin, Mengjie Weng, Jing Zheng, Kun Nie, Siyi Rao, Yongjie Zhuo, Jianxin Wan

J Diabetes Investig. 2024 Jan; 15(1): 87–105. Published online 2023 Sep 22. doi: 10.1111/jdi.14087

PMCID:: PMC10759719

Abstract Article PDF–11M

Select item 106228847.

Voltage-dependent anion channel 1 (VDAC1) overexpression alleviates cardiac fibroblast activation in cardiac fibrosis via regulating fatty acid metabolism

Geer Tian, Junteng Zhou, Yue Quan, Qihang Kong, Junli Li, Yanguo Xin, Wenchao Wu, Xiaoqiang Tang, Xiaojing Liu

Redox Biol. 2023 Nov; 67: 102907. Published online 2023 Sep 26. doi: 10.1016/j.redox.2023.102907

PMCID:: PMC10622884

Abstract Article PDF–16M

Select item 105206378.

NLRP14 Safeguards Calcium Homeostasis via Regulating the K27 Ubiquitination of Nclx in Oocyte‐to‐Embryo Transition

Tie‐Gang Meng, Jia‐Ni Guo, Liu Zhu, Yike Yin, Feng Wang, Zhi‐Ming Han, Lei Lei, Xue‐Shan Ma, Yue Xue, Wei Yue, Xiao‐Qing Nie, Zheng‐Hui Zhao, Hong‐Yong Zhang, Si‐Min Sun, Ying‐Chun Ouyang, Yi Hou, Heide Schatten, Zhenyu Ju, Xiang‐Hong Ou, Zhen‐Bo Wang, Catherine C. L. Wong, Zhonghan Li, Qing‐Yuan Sun

Adv Sci (Weinh) 2023 Sep; 10(27): 2301940. Published online 2023 Jul 26. doi: 10.1002/advs.202301940

PMCID:: PMC10520637

Abstract Article PDF–6.6M

Select item 105055769.

VDAC1通过诱导气道上皮细胞铁死亡参与屋尘螨诱导的哮喘小鼠气道炎症

黄奕, 林丽珊, 黄浩华, 董航明

Nan Fang Yi Ke Da Xue Xue Bao. 2023 Aug 20; 43(8): 1333–1338. Chinese. doi: 10.12122/j.issn.1673-4254.2023.08.09

PMCID:: PMC10505576

Abstract Article PDF–1.5M

Select item 1024549010.

DYNLT1 promotes mitochondrial metabolism to fuel breast cancer development by inhibiting ubiquitination degradation of VDAC1

Ling Huang, Bo Wei, Yuran Zhao, Xue Gong, Liming Chen

Mol Med. 2023; 29: 72. Published online 2023 Jun 6. doi: 10.1186/s10020-023-00663-0

PMCID:: PMC10245490

Abstract Article PDF–14M

Select item 1019392711.

Upregulation of the ERRγ–VDAC1 axis underlies the molecular pathogenesis of pancreatitis

Dipanjan Chanda, Themis Thoudam, Ibotombi Singh Sinam, Chae Won Lim, Myeongjin Kim, Jiale Wang, Kyeong-Min Lee, Jing Ma, Romil Saxena, Jinhyuk Choi, Chang Joo Oh, Hoyul Lee, Yong Hyun Jeon, Sung Jin Cho, Hoe-Yune Jung, Keun-Gyu Park, Hueng-Sik Choi, Jae Myoung Suh, Johan Auwerx, Baoan Ji, Suthat Liangpunsakul, Jae-Han Jeon, In-Kyu Lee

Proc Natl Acad Sci U S A. 2023 May 16; 120(20): e2219644120. Published online 2023 May 8. doi: 10.1073/pnas.2219644120

PMCID:: PMC10193927

Abstract Article PDF–3.4M

Select item 1017787212.

SAMHD1 Attenuates Acute Inflammation by Maintaining Mitochondrial Function in Macrophages via Interaction with VDAC1

Bowen Xu, Qianyi Sui, Han Hu, Xiangjia Hu, Xuchang Zhou, Cheng Qian, Nan Li

Int J Mol Sci. 2023 May; 24(9): 7888. Published online 2023 Apr 26. doi: 10.3390/ijms24097888

PMCID:: PMC10177872

Abstract Article PDF–5.8M

Select item 998255513.

MCU Upregulation Overactivates Mitophagy by Promoting VDAC1 Dimerization and Ubiquitination in the Hepatotoxicity of Cadmium

Cong Liu, Hui‐Juan Li, Wei‐Xia Duan, Yu Duan, Qin Yu, Tian Zhang, Ya‐Pei Sun, Yuan‐Yuan Li, Yong‐Sheng Liu, Shang‐Cheng Xu

Adv Sci (Weinh) 2023 Mar; 10(7): 2203869. Published online 2023 Jan 15. doi: 10.1002/advs.202203869

PMCID:: PMC9982555

Abstract Article PDF–4.7M

Select item 993821614.

Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub

Marc P. Forrest, Marc Dos Santos, Nicolas H. Piguel, Yi-Zhi Wang, Nicole A. Hawkins, Vikram A. Bagchi, Leonardo E. Dionisio, Sehyoun Yoon, Dina Simkin, Maria Dolores Martin-de-Saavedra, Ruoqi Gao, Katherine E. Horan, Alfred L. George, Jr., Mark S. LeDoux, Jennifer A. Kearney, Jeffrey N. Savas, Peter Penzes

Nat Commun. 2023; 14: 825. Published online 2023 Feb 17. doi: 10.1038/s41467-023-36087-x

PMCID:: PMC9938216

Abstract Article PDF–5.3M

Select item 993777515.

Inhibition of VDAC1 Rescues Aβ_1-42-Induced Mitochondrial Dysfunction and Ferroptosis via Activation of AMPK and Wnt/β-Catenin Pathways

Xinpei Zhou, Ximin Tang, Tao Li, Dandan Li, Zhiting Gong, Xiujun Zhang, Yanjiao Li, Jianhua Zhu, Yong Wang, Bensi Zhang

Mediators Inflamm. 2023; 2023: 6739691. Published online 2023 Feb 10. doi: 10.1155/2023/6739691

PMCID:: PMC9937775

Abstract Article PDF–2.7M

Select item 982946916.

Maternal exercise improves epithelial development of fetal intestine by enhancing apelin signaling and oxidative metabolism

Song Ah Chae, Jun Seok Son, Jeanene Marie de Avila, Min Du, Mei-Jun Zhu

Am J Physiol Regul Integr Comp Physiol. 2022 Nov 1; 323(5): R728–R738. Published online 2022 Oct 3. doi: 10.1152/ajpregu.00128.2022

PMCID:: PMC9829469

Abstract Article

Select item 960386017.

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3

Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany

Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527

PMCID:: PMC9603860

Abstract Article PDF–3.4M

Select item 938191818.

A partial reduction of VDAC1 enhances mitophagy, autophagy, synaptic activities in a transgenic Tau mouse model

Murali Vijayan, Rainier Vladlen Alvir, Razelle Veronique Alvir, Lloyd E. Bunquin, Jangampalli Adi Pradeepkiran, P. Hemachandra Reddy

Aging Cell. 2022 Aug; 21(8): e13663. Published online 2022 Jul 7. doi: 10.1111/acel.13663

PMCID:: PMC9381918

Abstract Article PDF–22M

Select item 936885219.

Reduced VDAC1, Maintained Mitochondrial Dynamics and Enhanced Mitochondrial Biogenesis in a Transgenic Tau Mouse Model of Alzheimer’s Disease

Murali Vijayan, P. Hemachandra Reddy

Int J Mol Sci. 2022 Aug; 23(15): 8561. Published online 2022 Aug 2. doi: 10.3390/ijms23158561

PMCID:: PMC9368852

Abstract Article PDF–1.3M

Select item 933533020.

Mitochondrial genome undergoes de novo DNA methylation that protects mtDNA against oxidative damage during the peri-implantation window

Yuan Yue, Likun Ren, Chao Zhang, Kai Miao, Kun Tan, Qianying Yang, Yupei Hu, Guangyin Xi, Gang Luo, Mingyao Yang, Jingyu Zhang, Zhuocheng Hou, Lei An, Jianhui Tian

Proc Natl Acad Sci U S A. 2022 Jul 26; 119(30): e2201168119. Published online 2022 Jul 18. doi: 10.1073/pnas.2201168119

PMCID:: PMC9335330

Abstract Article PDF–2.1M

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