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Items: 1 to 20 of 97

1.
AUP1 transcriptionally activated by KDM5B reprograms lipid metabolism to promote the malignant progression of cervical cancer
Yingping Zhu, Wenjuan Yang, Xinyan Wang, Mengmeng Chen
Int J Oncol. 2024 Nov; 65(5): 107. Published online 2024 Sep 20. doi: 10.3892/ijo.2024.5695
PMCID:
PMC11436259
AbstractArticlePDF–19M
2.
A Genotype/Phenotype Study of KDM5B-Associated Disorders Suggests a Pathogenic Effect of Dominantly Inherited Missense Variants
Maria Carla Borroto, Coralie Michaud, Chloé Hudon, Pankaj B. Agrawal, Katherine Agre, Carolyn D. Applegate, Alan H. Beggs, Hans T. Bjornsson, Bert Callewaert, Mei-Jan Chen, Cynthia Curry, Orrin Devinsky, Tracy Dudding-Byth, Kelly Fagan, Candice R. Finnila, Ralitza Gavrilova, Casie A. Genetti, Susan M. Hiatt, Friedhelm Hildebrandt, Monica H. Wojcik, Tjitske Kleefstra, Caroline M. Kolvenbach, Bruce R. Korf, Paul Kruszka, Hong Li, Jessica Litwin, Julien Marcadier, Konrad Platzer, Patrick R. Blackburn, Margot R. F. Reijnders, Heiko Reutter, Ina Schanze, Joseph T. Shieh, Cathy A. Stevens, Zaheer Valivullah, Marie-José van den Boogaard, Eric W. Klee, Philippe M. Campeau
Genes (Basel) 2024 Aug; 15(8): 1033. Published online 2024 Aug 6. doi: 10.3390/genes15081033
PMCID:
PMC11353349
AbstractArticlePDF–946K
3.
LncRNA HOXC-AS3 accelerates malignant proliferation of cervical cancer cells via stabilizing KDM5B
Jie Li, Fang Hou, Zhenghua Teng, Weiwei Xia, Jie Peng
J Cancer Res Clin Oncol. 2024; 150(6): 294. Published online 2024 Jun 6. doi: 10.1007/s00432-024-05799-y
PMCID:
PMC11156713
AbstractArticlePDF–7.8M
4.
Deubiquitinase USP7 stabilizes KDM5B and promotes tumor progression and cisplatin resistance in nasopharyngeal carcinoma through the ZBTB16/TOP2A axis
Bin Zhang, Jie Li, Yijun Wang, Xixi Liu, Xiao Yang, Zhiyun Liao, Suke Deng, Yue Deng, Zhiyuan Zhou, Yu Tian, Wenwen Wei, Jingshu Meng, Yan Hu, Chao Wan, Zhanjie Zhang, Fang Huang, Lu Wen, Bian Wu, Yajie Sun, Yan Li, Kunyu Yang
Cell Death Differ. 2024 Mar; 31(3): 309–321. Published online 2024 Jan 29. doi: 10.1038/s41418-024-01257-x
PMCID:
PMC10923876
AbstractArticlePDF–8.3M
5.
Primary complex motor stereotypies are associated with de novo damaging DNA coding mutations that identify KDM5B as a risk gene
Thomas V. Fernandez, Zsanett P. Williams, Tina Kline, Shreenath Rajendran, Farhan Augustine, Nicole Wright, Catherine A. W. Sullivan, Emily Olfson, Sarah B. Abdallah, Wenzhong Liu, Ellen J. Hoffman, Abha R. Gupta, Harvey S. Singer
PLoS One. 2023; 18(10): e0291978. Published online 2023 Oct 3. doi: 10.1371/journal.pone.0291978
PMCID:
PMC10547198
AbstractArticlePDF–1.2M
6.
A truncated and catalytically inactive isoform of KDM5B histone demethylase accumulates in breast cancer cells and regulates H3K4 tri-methylation and gene expression
Elena Di Nisio, Valerio Licursi, Cecilia Mannironi, Valentina Buglioni, Alessandro Paiardini, Giulia Robusti, Roberta Noberini, Tiziana Bonaldi, Rodolfo Negri
Cancer Gene Ther. 2023; 30(6): 822–832. Published online 2023 Jan 26. doi: 10.1038/s41417-022-00584-w
PMCID:
PMC10281864
AbstractArticlePDF–3.0M
7.
PLU1 Promotes the Proliferation and Migration of Glioma Cells and Regulates Metabolism
Wentao Dong, Lude Wang, Yi Pan, Qi Tu, Ting He, Tian Zhou, Jianlie Yuan, Minfeng Tong
Technol Cancer Res Treat. 2023; 22: 15330338231175768. Published online 2023 May 30. doi: 10.1177/15330338231175768
PMCID:
PMC10240554
AbstractArticlePDF–4.6M
8.
Drawing a line between histone demethylase KDM5A and KDM5B: their roles in development and tumorigenesis
Jung Yoo, Go Woon Kim, Yu Hyun Jeon, Ji Yoon Kim, Sang Wu Lee, So Hee Kwon
Exp Mol Med. 2022 Dec; 54(12): 2107–2117. Published online 2022 Dec 12. doi: 10.1038/s12276-022-00902-0
PMCID:
PMC9794821
AbstractArticlePDF–2.1M
9.
H3K4 demethylase KDM5B regulates cancer cell identity and epigenetic plasticity
Runsheng He, Besa Xhabija, Lijin K. Gopi, Jiji T. Kurup, Zhishan Xu, Zhe Liu, Benjamin L. Kidder
Oncogene. Author manuscript; available in PMC 2022 Nov 1.
Published in final edited form as: Oncogene. 2022 May; 41(21): 2958–2972. Published online 2022 Apr 19. doi: 10.1038/s41388-022-02311-z
PMCID:
PMC9426628
AbstractArticlePDF–4.1M
10.
Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease
Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel
Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205
PMCID:
PMC9348576
AbstractArticlePDF–3.0M
11.
Overcoming radio-resistance in esophageal squamous cell carcinoma via hypermethylation of PIK3C3 promoter region mediated by KDM5B loss
Xiaobo Wang, Min Gu, Yongjian Ju, Juying Zhou
J Radiat Res. 2022 May; 63(3): 331–341. Published online 2022 Mar 25. doi: 10.1093/jrr/rrac004
PMCID:
PMC9124615
AbstractArticlePDF–2.0M
12.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
13.
Quantitative Interaction Proteomics of Neurodegenerative Disease Proteins
Fabian Hosp, Hannes Vossfeldt, Matthias Heinig, Djordje Vasiljevic, Anup Arumughan, Emanuel Wyler, Genetic and Environmental Risk for Alzheimer’s Disease (GERAD1) Consortium, Markus Landthaler, Norbert Hubner, Erich E. Wanker, Lars Lannfelt, Martin Ingelsson, Maciej Lalowski, Aaron Voigt, Matthias Selbach
Cell Rep. Author manuscript; available in PMC 2022 Apr 18.
Published in final edited form as: Cell Rep. 2015 May 19; 11(7): 1134–1146. Published online 2015 May 7. doi: 10.1016/j.celrep.2015.04.030
PMCID:
PMC9014711
AbstractArticlePDF–2.2M
14.
KDM5B promotes tumorigenesis of Ewing sarcoma via FBXW7/CCNE1 axis
Binbin Chen, Huimou Chen, Suying Lu, Xiaoqin Zhu, Yi Que, Yu Zhang, Junting Huang, Li Zhang, Yu Zhang, Feifei Sun, Juan Wang, Jia Zhu, Zijun Zhen, Yizhuo Zhang
Cell Death Dis. 2022 Apr; 13(4): 354. Published online 2022 Apr 15. doi: 10.1038/s41419-022-04800-1
PMCID:
PMC9012801
AbstractArticlePDF–6.9M
15.
Circ_0087960 stabilizes KDM5B by reducing SKP2 mediated ubiquitination degradation and promotes osteogenic differentiation in periodontal ligament stem cells
Yinchen Liu, Yanbin Zhou
Regen Ther. 2022 Mar; 19: 122–130. Published online 2022 Feb 10. doi: 10.1016/j.reth.2022.01.003
PMCID:
PMC8844145
AbstractArticlePDF–2.5M
16.
Hypoxia Stimulates SUMOylation-Dependent Stabilization of KDM5B
Bingluo Zhou, Yiran Zhu, Wenxia Xu, Qiyin Zhou, Linghui Tan, Liyuan Zhu, Hui Chen, Lifeng Feng, Tianlun Hou, Xian Wang, Dingwei Chen, Hongchuan Jin
Front Cell Dev Biol. 2021; 9: 741736. Published online 2021 Dec 17. doi: 10.3389/fcell.2021.741736
PMCID:
PMC8719622
AbstractArticlePDF–3.7M
17.
KDM5B Promotes Immune Evasion by Recruiting SETDB1 to Silence Retroelements
Shang-Min Zhang, Wesley L. Cai, Xiaoni Liu, Durga Thakral, Jiesi Luo, Lok Hei Chan, Meaghan K. McGeary, Eric Song, Kim RM Blenman, Goran Micevic, Shlomit Jessel, Yangyi Zhang, Mingzhu Yin, Carmen J. Booth, Lucia B. Jilaveanu, William Damsky, Mario Sznol, Harriet M. Kluger, Akiko Iwasaki, Marcus W. Bosenberg, Qin Yan
Nature. Author manuscript; available in PMC 2022 Apr 20.
Published in final edited form as: Nature. 2021 Oct; 598(7882): 682–687. Published online 2021 Oct 20. doi: 10.1038/s41586-021-03994-2
PMCID:
PMC8555464
AbstractArticlePDF–5.8M
18.
Agenesis of the Corpus Callosum with Facial Dysmorphism and Intellectual Disability in Sibs Associated with Compound Heterozygous KDM5B Variants
Sébastien Lebon, Mathieu Quinodoz, Virginie G. Peter, Carole Gengler, Gaëlle Blanchard, Viviane Cina, Belinda Campos-Xavier, Carlo Rivolta, Andrea Superti-Furga
Genes (Basel) 2021 Sep; 12(9): 1397. Published online 2021 Sep 10. doi: 10.3390/genes12091397
PMCID:
PMC8467522
AbstractArticlePDF–592K
19.
KDM5A and KDM5B histone-demethylases contribute to HU-induced replication stress response and tolerance
Solenne Gaillard, Virginie Charasson, Cyril Ribeyre, Kader Salifou, Marie-Jeanne Pillaire, Jean-Sebastien Hoffmann, Angelos Constantinou, Didier Trouche, Marie Vandromme
Biol Open. 2021 May 15; 10(5): bio057729. Published online 2021 May 26. doi: 10.1242/bio.057729
PMCID:
PMC8181900
AbstractArticlePDF–5.6M
20.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M

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