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Select item 69305631.

Oroxin B Induces Apoptosis by Down-Regulating MicroRNA-221 Resulting in the Inactivation of the PTEN/PI3K/AKT Pathway in Liver Cancer

Nannan Li, Wenxiao Men, Yibo Zheng, Hechen Wang, Xiansheng Meng

Molecules. 2019 Dec; 24(23): 4384. Published online 2019 Nov 30. doi: 10.3390/molecules24234384

PMCID:: PMC6930563

Abstract Article PDF–6.9M

Select item 67251212.

Protein-Protein Coupling/Uncoupling Enables Dopamine D₂ Receptor Regulation of AMPA Receptor-Mediated Excitotoxicity

Shengwei Zou, Lei Li, Lin Pei, Brian Vukusic, Hubert H. M. Van Tol, Frank J. S. Lee, Qi Wan, Fang Liu

J Neurosci. 2005 Apr 27; 25(17): 4385–4395. doi: 10.1523/JNEUROSCI.5099-04.2005

PMCID:: PMC6725121

Abstract Article PDF–779K

Select item 66749643.

Differential Reelin-Induced Enhancement of NMDA and AMPA Receptor Activity in the Adult Hippocampus

Shenfeng Qiu, Lisa F. Zhao, Kimberly M. Korwek, Edwin J. Weeber

J Neurosci. 2006 Dec 13; 26(50): 12943–12955. doi: 10.1523/JNEUROSCI.2561-06.2006

PMCID:: PMC6674964

Abstract Article PDF–764K

Select item 66745944.

Estrogen Receptor Protein Interaction with Phosphatidylinositol 3-Kinase Leads to Activation of Phosphorylated Akt and Extracellular Signal-Regulated Kinase 1/2 in the Same Population of Cortical Neurons: A Unified Mechanism of Estrogen Action

Paolo Mannella, Roberta Diaz Brinton

J Neurosci. 2006 Sep 13; 26(37): 9439–9447. doi: 10.1523/JNEUROSCI.1443-06.2006

PMCID:: PMC6674594

Abstract Article PDF–547K

Select item 66237695.

Phosphoinositide-3-Kinase Activation Controls Synaptogenesis and Spinogenesis in Hippocampal Neurons

Germán Cuesto, Lilian Enriquez-Barreto, Cristina Caramés, Marta Cantarero, Xavier Gasull, Carmen Sandi, Alberto Ferrús, Ángel Acebes, Miguel Morales

J Neurosci. 2011 Feb 23; 31(8): 2721–2733. doi: 10.1523/JNEUROSCI.4477-10.2011

PMCID:: PMC6623769

Abstract Article PDF–1.8M

Select item 53224456.

Wei Jiang, Wenjue Zhang, Lihong Wu, Lipin Liu, Yu Men, Jingbo Wang, Jun Liang, Zhouguang Hui, Zongmei Zhou, Nan Bi, Luhua Wang

Biomed Res Int. 2017; 2017: 6501385. Published online 2017 Feb 9. doi: 10.1155/2017/6501385

PMCID:: PMC5322445

Abstract Article PDF–701K

Select item 49914437.

Survival kinase genes present prognostic significance in glioblastoma

Robin T. Varghese, Yanping Liang, Ting Guan, Christopher T. Franck, Deborah F. Kelly, Zhi Sheng

Oncotarget. 2016 Apr 12; 7(15): 20140–20151. Published online 2016 Mar 4. doi: 10.18632/oncotarget.7917

PMCID:: PMC4991443

Abstract Article PDF–9.5M

Select item 45989818.

MicroRNA-542-3p Suppresses Tumor Cell Invasion via Targeting AKT Pathway in Human Astrocytoma

Junchao Cai, JingJing Zhao, Nu Zhang, Xiaonan Xu, Rong Li, Yang Yi, Lishan Fang, Le Zhang, Mengfeng Li, Jueheng Wu, Heng Zhang

J Biol Chem. 2015 Oct 9; 290(41): 24678–24688. Published online 2015 Aug 18. doi: 10.1074/jbc.M115.649004

PMCID:: PMC4598981

Abstract Article PDF–1.9M

Select item 45164829.

Mechanisms underlying fibronectin-induced up-regulation of P2X₄R expression in microglia: distinct roles of PI3K–Akt and MEK–ERK signalling pathways

Makoto Tsuda, Emika Toyomitsu, Miho Kometani, Hidetoshi Tozaki-Saitoh, Kazuhide Inoue

J Cell Mol Med. 2009 Sep; 13(9b): 3251–3259. Published online 2009 Feb 27. doi: 10.1111/j.1582-4934.2009.00719.x

PMCID:: PMC4516482

Abstract Article PDF–777K

Select item 444025410.

Garlic Oil Suppressed Nitrosodiethylamine-Induced Hepatocarcinoma in Rats by Inhibiting PI3K-AKT-NF-κB Pathway

Cui-Li Zhang, Tao Zeng, Xiu-Lan Zhao, Ke-Qin Xie

Int J Biol Sci. 2015; 11(6): 643–651. Published online 2015 Apr 25. doi: 10.7150/ijbs.10785

PMCID:: PMC4440254

Abstract Article PDF–1.4M

Select item 437160611.

A Novel Interaction Between the Regulatory Subunit of PI 3-Kinase and X-box Binding Protein-1 Modulates the Unfolded Protein Response

Jonathon N. Winnay, Jeremie Boucher, Marcelo Mori, Kohjiro Ueki, C. Ronald Kahn

Nat Med. Author manuscript; available in PMC 2015 Mar 24.

Published in final edited form as: Nat Med. 2010 Apr; 16(4): 438–445. Published online 2010 Mar 28. doi: 10.1038/nm.2121

PMCID:: PMC4371606

Abstract Article PDF–1.6M

Select item 435572912.

PIK3R1 negatively regulates the epithelial-mesenchymal transition and stem-like phenotype of renal cancer cells through the AKT/GSK3β/CTNNB1 signaling pathway

Youcheng Lin, Zhao Yang, Abai Xu, Pei Dong, Yi Huang, Huan Liu, Feida Li, Haifeng Wang, Qian Xu, Yongqiang Wang, Da Sun, Yong Zou, Xiaowen Zou, Yu Wang, Duo Zhang, Hongjie Liu, Xun Wu, Meng Zhang, Yu Fu, Zhiming Cai, Chunxiao Liu, Song Wu

Sci Rep. 2015; 5: 8997. Published online 2015 Mar 11. doi: 10.1038/srep08997

PMCID:: PMC4355729

Abstract Article PDF–1.9M

Select item 424429313.

Exogenous Leptin Administered Intramuscularly Induces Sex Hormone Disorder and Ca Loss via Downregulation of Gnrh and PI3K Expression

Lihong Wu, Wen Liu, Nashun Bayaer, Weiwang Gu, Jieli Song

Exp Anim. 2014; 63(4): 447–457. Published online 2014 Jul 22. doi: 10.1538/expanim.63.447

PMCID:: PMC4244293

Abstract Article PDF–1.0M

Select item 419744114.

Phosphoinositide 3-kinase p85beta regulates invadopodium formation

Ariel E. Cariaga-Martínez, Isabel Cortés, Esther García, Vicente Pérez-García, María J. Pajares, Miguel A. Idoate, Javier Redondo-Muñóz, Inés M. Antón, Ana C. Carrera

Biol Open. 2014 Oct 15; 3(10): 924–936. Published online 2014 Sep 12. doi: 10.1242/bio.20148185

PMCID:: PMC4197441

Abstract Article PDF–2.0M

Select item 370473015.

Integrated genomic characterization of endometrial carcinoma

Douglas A. Levine, The Cancer Genome Atlas Research Network

Nature. 2013; 497(7447): 67–73. Published online 2013 May 1. doi: 10.1038/nature12113

Correction in:: volume 500 on page 242

PMCID:: PMC3704730

Abstract Article PDF–1.9M

Select item 318755516.

High Frequency of PIK3R1 and PIK3R2 Mutations in Endometrial Cancer Elucidates a Novel Mechanism for Regulation of PTEN Protein Stability

Lydia W.T. Cheung, Bryan T. Hennessy, Jie Li, Shuangxing Yu, Andrea P. Myers, Bojana Djordjevic, Yiling Lu, Katherine Stemke-Hale, Fan Zhang, Zhenlin Ju, Lewis C. Cantley, Steven E. Scherer, Han Liang, Karen H. Lu, Russell R. Broaddus, Gordon B. Mills

Cancer Discov. Author manuscript; available in PMC 2012 Jul 1.

Published in final edited form as: Cancer Discov. 2011 Jul 1; 1(2): 170–185. doi: 10.1158/2159-8290.CD-11-0039

PMCID:: PMC3187555

Abstract Article PDF–1.3M

Select item 317805917.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 311707118.

PIK3R1 (p85-alpha/p85α) is Somatically Mutated at High Frequency in Primary Endometrial Cancer

Mary Ellen Urick, Meghan L. Rudd, Andrew K. Godwin, Dennis Sgroi, Maria Merino, Daphne W. Bell

Cancer Res. Author manuscript; available in PMC 2012 Jun 15.

Published in final edited form as: Cancer Res. 2011 Jun 15; 71(12): 4061–4067. Published online 2011 Apr 8. doi: 10.1158/0008-5472.CAN-11-0549

PMCID:: PMC3117071

Abstract Article PDF–193K

Select item 311184219.

Interleukin-18/WNT1-Inducible Signaling Pathway Protein-1 signaling mediates human saphenous vein smooth muscle cell proliferation

VENKATAPURAM SEENU REDDY, ANTHONY J. VALENTE, PATRICE DELAFONTAINE, BYSANI CHANDRASEKAR

J Cell Physiol. Author manuscript; available in PMC 2012 Dec 1.

Published in final edited form as: J Cell Physiol. 2011 Dec; 226(12): 3303–3315. doi: 10.1002/jcp.22676

PMCID:: PMC3111842

Abstract Article PDF–1.3M

Select item 307101220.

The regulatory subunits of PI3K, p85α and p85β, interact with XBP-1 and increase its nuclear translocation

Sang Won Park, Yingjiang Zhou, Justin Lee, Allen Lu, Cheng Sun, Jason Chung, Kohjiro Ueki, Umut Ozcan

Nat Med. Author manuscript; available in PMC 2011 Apr 5.

Published in final edited form as: Nat Med. 2010 Apr; 16(4): 429–437. Published online 2010 Mar 28. doi: 10.1038/nm.2099

PMCID:: PMC3071012

Abstract Article PDF–2.7M

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