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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 90747442.

Illumination of the Endogenous Insulin-Regulated TBC1D4 Interactome in Human Skeletal Muscle

Jeppe K. Larsen, Magnus R. Larsen, Jesper B. Birk, Dorte E. Steenberg, Janne R. Hingst, Kurt Højlund, Alexandra Chadt, Hadi Al-Hasani, Atul S. Deshmukh, Jørgen F.P. Wojtaszewski, Rasmus Kjøbsted

Diabetes. 2022 May; 71(5): 906–920. Published online 2022 Feb 22. doi: 10.2337/db21-0855

PMCID:: PMC9074744

Abstract Article PDF–3.0M

Select item 90156993.

The ATG5 interactome links clathrin-mediated vesicular trafficking with the autophagosome assembly machinery

Kiren Baines, Kazuaki Yoshioka, Yoh Takuwa, Jon D. Lane

Autophagy Rep. 2022; 1(1): 88–118. Published online 2022 Apr 7. doi: 10.1080/27694127.2022.2042054

PMCID:: PMC9015699

Abstract Article PDF–3.3M

Select item 88096064.

Rab2A regulates the progression of nonalcoholic fatty liver disease downstream of AMPK-TBC1D1 axis by stabilizing PPARγ

Zi-Yue Chen, Ya-Ting Sun, Zi-Ming Wang, Jie Hong, Min Xu, Fu-Ting Zhang, Xian-Qing Zhou, Ping Rong, Qi Wang, Hong Yu Wang, Hua Wang, Shuai Chen, Liang Chen

PLoS Biol. 2022 Jan; 20(1): e3001522. Published online 2022 Jan 21. doi: 10.1371/journal.pbio.3001522

PMCID:: PMC8809606

Abstract Article PDF–5.3M

Select item 79387705.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 74159916.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 61567657.

Isoform-specific AMPK association with TBC1D1 is reduced by a mutation associated with severe obesity

Elaine C. Thomas, Sharon C. Hook, Alexander Gray, Alexandra Chadt, David Carling, Hadi Al-Hasani, Kate J. Heesom, D. Grahame Hardie, Jeremy M. Tavaré

Biochem J. 2018 Sep 28; 475(18): 2969–2983. Prepublished online 2018 Aug 22. Published online 2018 Sep 25. doi: 10.1042/BCJ20180475

PMCID:: PMC6156765

Abstract Article PDF–2.2M

Select item 49329508.

Disruption of the AMPK–TBC1D1 nexus increases lipogenic gene expression and causes obesity in mice via promoting IGF1 secretion

Liang Chen, Qiaoli Chen, Bingxian Xie, Chao Quan, Yang Sheng, Sangsang Zhu, Ping Rong, Shuilian Zhou, Kei Sakamoto, Carol MacKintosh, Hong Yu Wang, Shuai Chen

Proc Natl Acad Sci U S A. 2016 Jun 28; 113(26): 7219–7224. Published online 2016 Jun 15. doi: 10.1073/pnas.1600581113

PMCID:: PMC4932950

Abstract Article PDF–1.3M

Select item 48885289.

Rab GAPs AS160 and Tbc1d1 play nonredundant roles in the regulation of glucose and energy homeostasis in mice

Stefan R. Hargett, Natalie N. Walker, Susanna R. Keller

Am J Physiol Endocrinol Metab. 2016 Feb 15; 310(4): E276–E288. Published online 2015 Dec 1. doi: 10.1152/ajpendo.00342.2015

PMCID:: PMC4888528

Abstract Article

Select item 452511610.

Deletion of the Rab GAP Tbc1d1 modifies glucose, lipid, and energy homeostasis in mice

Stefan R. Hargett, Natalie N. Walker, Syed S. Hussain, Kyle L. Hoehn, Susanna R. Keller

Am J Physiol Endocrinol Metab. 2015 Aug 1; 309(3): E233–E245. Published online 2015 May 26. doi: 10.1152/ajpendo.00007.2015

PMCID:: PMC4525116

Abstract Article

Select item 396495511.

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data

Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson

Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977

PMCID:: PMC3964955

Abstract Article PDF–5.7M

Select item 359625112.

Regulatory mode shift of Tbc1d1 is required for acquisition of insulin-responsive GLUT4-trafficking activity

Hiroyasu Hatakeyama, Makoto Kanzaki

Mol Biol Cell. 2013 Mar 15; 24(6): 809–817. doi: 10.1091/mbc.E12-10-0725

PMCID:: PMC3596251

Abstract Article PDF–2.9M

Select item 357241013.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 336197814.

Thr⁶⁴⁹Ala-AS160 knock-in mutation does not impair contraction/AICAR-induced glucose transport in mouse muscle

Serge Ducommun, Hong Yu Wang, Kei Sakamoto, Carol MacKintosh, Shuai Chen

Am J Physiol Endocrinol Metab. 2012 May 1; 302(9): E1036–E1043. Published online 2012 Feb 7. doi: 10.1152/ajpendo.00379.2011

PMCID:: PMC3361978

Abstract Article

Select item 325378115.

Leptin Reduces the Expression and Increases the Phosphorylation of the Negative Regulators of GLUT4 Traffic TBC1D1 and TBC1D4 in Muscle of ob/ob Mice

Neira Sáinz, Amaia Rodríguez, Victoria Catalán, Sara Becerril, Beatriz Ramírez, Andoni Lancha, Emma Burgos-Ramos, Javier Gómez-Ambrosi, Gema Frühbeck

PLoS One. 2012; 7(1): e29389. Published online 2012 Jan 9. doi: 10.1371/journal.pone.0029389

PMCID:: PMC3253781

Abstract Article PDF–3.2M

Select item 317805916.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 302253417.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Abstract Article PDF–3.8M

Select item 300885618.

Exercise-induced TBC1D1 Ser237 phosphorylation and 14-3-3 protein binding capacity in human skeletal muscle

Christian Frøsig, Christian Pehmøller, Jesper B Birk, Erik A Richter, Jørgen F P Wojtaszewski

J Physiol. 2010 Nov 15; 588(Pt 22): 4539–4548. Published online 2010 Sep 13. doi: 10.1113/jphysiol.2010.194811

PMCID:: PMC3008856

Abstract Article PDF–393K

Select item 300883719.

Of mice and men: filling gaps in the TBC1D1 story

Gregory D Cartee

J Physiol. 2010 Nov 15; 588(Pt 22): 4331–4332. doi: 10.1113/jphysiol.2010.199794

PMCID:: PMC3008837

Article PDF–55K

Select item 294719320.

Contraction regulates site-specific phosphorylation of TBC1D1 in skeletal muscle

Kanokwan Vichaiwong, Suneet Purohit, Ding An, Taro Toyoda, Niels Jessen, Michael F. Hirshman, Laurie J. Goodyear

Biochem J. 2010 Oct 15; 431(Pt 2): 311–320. Prepublished online 2010 Aug 11. Published online 2010 Sep 28. doi: 10.1042/BJ20101100

PMCID:: PMC2947193

Abstract Article PDF–1015K

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