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Select item 108974891.

The NSP3 protein of SARS-CoV-2 binds fragile X mental retardation proteins to disrupt UBAP2L interactions

Dimitriya H Garvanska, R Elias Alvarado, Filip Oskar Mundt, Richard Lindqvist, Josephine Kerzel Duel, Fabian Coscia, Emma Nilsson, Kumari Lokugamage, Bryan A Johnson, Jessica A Plante, Dorothea R Morris, Michelle N Vu, Leah K Estes, Alyssa M McLeland, Jordyn Walker, Patricia A Crocquet-Valdes, Blanca Lopez Mendez, Kenneth S Plante, David H Walker, Melanie Bianca Weisser, Anna K Överby, Matthias Mann, Vineet D Menachery, Jakob Nilsson

EMBO Rep. 2024 Feb; 25(2): 902–926. Published online 2024 Jan 2. doi: 10.1038/s44319-023-00043-z

PMCID:: PMC10897489

Abstract Article PDF–8.2M

Select item 97272222.

Type 1 interferon suppresses expression and glucocorticoid induction of glucocorticoid-induced leucine zipper (GILZ)

Wendy Dankers, Melissa Northcott, Taylah Bennett, Akshay D’Cruz, Rochelle Sherlock, Linden J. Gearing, Paul Hertzog, Brendan Russ, Iolanda Miceli, Sebastian Scheer, Maki Fujishiro, Kunihiro Hayakawa, Keigo Ikeda, Eric F. Morand, Sarah A. Jones

Front Immunol. 2022; 13: 1034880. Published online 2022 Nov 23. doi: 10.3389/fimmu.2022.1034880

PMCID:: PMC9727222

Abstract Article PDF–7.3M

Select item 91197363.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 91005314.

Expression Profiles of GILZ and Annexin A1 in Human Oral Candidiasis and Lichen Planus

Mahmood S. Mozaffari, Rafik Abdelsayed

Cells. 2022 May; 11(9): 1470. Published online 2022 Apr 27. doi: 10.3390/cells11091470

PMCID:: PMC9100531

Abstract Article PDF–2.8M

Select item 81650305.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 80850116.

Glucocorticoid-induced leucine zipper regulates liver fibrosis by suppressing CCL2-mediated leukocyte recruitment

Sara Flamini, Philipp Sergeev, Zenobio Viana de Barros, Tommaso Mello, Michele Biagioli, Musetta Paglialunga, Chiara Fiorucci, Tatiana Prikazchikova, Stefano Pagano, Andrea Gagliardi, Carlo Riccardi, Timofei Zatsepin, Graziella Migliorati, Oxana Bereshchenko, Stefano Bruscoli

Cell Death Dis. 2021 May; 12(5): 421. Published online 2021 Apr 29. doi: 10.1038/s41419-021-03704-w

PMCID:: PMC8085011

Abstract Article PDF–2.0M

Select item 74273277.

Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases

Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger

Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001

PMCID:: PMC7427327

Abstract Article

Select item 73522028.

An Integrative Synthetic Biology Approach to Interrogating Cellular Ubiquitin and Ufm Signaling

Chuanyin Li, Tianting Han, Rong Guo, Peng Chen, Chao Peng, Gali Prag, Ronggui Hu

Int J Mol Sci. 2020 Jun; 21(12): 4231. Published online 2020 Jun 14. doi: 10.3390/ijms21124231

PMCID:: PMC7352202

Abstract Article PDF–1.5M

Select item 73220679.

RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation

Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen

Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117

PMCID:: PMC7322067

Abstract Article PDF–2.7M

Select item 717685510.

Glucocorticoid‐transactivated TSC22D3 attenuates hypoxia‐ and diabetes‐induced Müller glial galectin‐1 expression via HIF‐1α destabilization

Atsuhiro Kanda, Ikuyo Hirose, Kousuke Noda, Miyuki Murata, Susumu Ishida

J Cell Mol Med. 2020 Apr; 24(8): 4589–4599. Published online 2020 Mar 9. doi: 10.1111/jcmm.15116

PMCID:: PMC7176855

Abstract Article PDF–1.0M

Select item 716998311.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 700871212.

Short-Chain Alcohols Upregulate GILZ Gene Expression and Attenuate LPS-Induced Septic Immune Response

Hang Pong Ng, Yubo Wang, Scott Jennings, Steve Nelson, Guoshun Wang

Front Immunol. 2020; 11: 53. Published online 2020 Feb 3. doi: 10.3389/fimmu.2020.00053

Correction in:: Front Immunol. 2022; 13: 876794.

PMCID:: PMC7008712

Abstract Article PDF–1.7M

Select item 675363913.

Glucocorticoids and Glucocorticoid-Induced-Leucine-Zipper (GILZ) in Psoriasis

Lisa M. Sevilla, Paloma Pérez

Front Immunol. 2019; 10: 2220. Published online 2019 Sep 13. doi: 10.3389/fimmu.2019.02220

PMCID:: PMC6753639

Abstract Article PDF–815K

Select item 673886114.

Glucocorticoid-Induced Leucine Zipper Is Expressed in Human Neutrophils and Promotes Apoptosis through Mcl-1 Down-Regulation

Marie-Alix Espinasse, Aurélie Pépin, Pauline Virault-Rocroy, Natacha Szely, Sylvie Chollet-Martin, Marc Pallardy, Armelle Biola-Vidamment

J Innate Immun. 2016 Jan; 8(1): 81–96. Published online 2015 Sep 19. doi: 10.1159/000439052

PMCID:: PMC6738861

Abstract Article PDF–469K

Select item 669338915.

Implicating the Role of GILZ in Glucocorticoid Modulation of T-Cell Activation

Lorenza Cannarile, Domenico V. Delfino, Sabrina Adorisio, Carlo Riccardi, Emira Ayroldi

Front Immunol. 2019; 10: 1823. Published online 2019 Aug 7. doi: 10.3389/fimmu.2019.01823

PMCID:: PMC6693389

Abstract Article PDF–1.5M

Select item 665856116.

Glucocorticoid-induced leucine zipper “quantifies” stressors and increases male susceptibility to PTSD

Maya A. Lebow, Mariana Schroeder, Michael Tsoory, Dorin Holzman-Karniel, Divya Mehta, Shifra Ben-Dor, Shosh Gil, Bekh Bradley, Alicia K. Smith, Tanja Jovanovic, Kerry J. Ressler, Elisabeth B. Binder, Alon Chen

Transl Psychiatry. 2019; 9: 178. Published online 2019 Jul 25. doi: 10.1038/s41398-019-0509-3

PMCID:: PMC6658561

Abstract Article PDF–2.0M

Select item 634969817.

Amplified Host Defense by Toll-Like Receptor-Mediated Downregulation of the Glucocorticoid-Induced Leucine Zipper (GILZ) in Macrophages

Jessica Hoppstädter, Britta Diesel, Rebecca Linnenberger, Nina Hachenthal, Sara Flamini, Marie Minet, Petra Leidinger, Christina Backes, Friedrich Grässer, Eckart Meese, Stefano Bruscoli, Carlo Riccardi, Hanno Huwer, Alexandra K. Kiemer

Front Immunol. 2018; 9: 3111. Published online 2019 Jan 22. doi: 10.3389/fimmu.2018.03111

PMCID:: PMC6349698

Abstract Article PDF–1.9M

Select item 599726018.

Transcriptome-Wide Analysis Identifies Novel Associations With Blood Pressure

Tanja Zeller, Claudia Schurmann, Katharina Schramm, Christian Müller, Soonil Kwon, Philipp S. Wild, Alexander Teumer, David Herrington, Arne Schillert, Licia Iacoviello, Adelheid Kratzer, Annika Jagodzinski, Mahir Karakas, Jingzhong Ding, Johannes T. Neumann, Kari Kuulasmaa, Christian Gieger, Tim Kacprowski, Renate B. Schnabel, Michael Roden, Simone Wahl, Jerome I. Rotter, Francisco Ojeda, Maren Carstensen-Kirberg, David-Alexandre Tregouet, Marcus Dörr, Thomas Meitinger, Karl J. Lackner, Petra Wolf, Stephan B. Felix, Ulf Landmesser, Simona Costanzo, Andreas Ziegler, Yongmei Liu, Uwe Völker, Walter Palmas, Holger Prokisch, Xiuqing Guo, Christian Herder, Stefan Blankenberg, Georg Homuth

Hypertension. Author manuscript; available in PMC 2018 Oct 1.

Published in final edited form as: Hypertension. 2017 Oct; 70(4): 743–750. Published online 2017 Aug 7. doi: 10.1161/HYPERTENSIONAHA.117.09458

PMCID:: PMC5997260

Abstract Article PDF–435K

Select item 586483219.

An AP-MS- and BioID-compatible MAC-tag enables comprehensive mapping of protein interactions and subcellular localizations

Xiaonan Liu, Kari Salokas, Fitsum Tamene, Yaming Jiu, Rigbe G. Weldatsadik, Tiina Öhman, Markku Varjosalo

Nat Commun. 2018; 9: 1188. Published online 2018 Mar 22. doi: 10.1038/s41467-018-03523-2

PMCID:: PMC5864832

Abstract Article PDF–4.5M

Select item 583386920.

Long glucocorticoid-induced leucine zipper regulates human thyroid cancer cell proliferation

Emira Ayroldi, Maria Grazia Petrillo, Maria Cristina Marchetti, Lorenza Cannarile, Simona Ronchetti, Erika Ricci, Luigi Cari, Nicola Avenia, Sonia Moretti, Efisio Puxeddu, Carlo Riccardi

Cell Death Dis. 2018 Mar; 9(3): 305. Published online 2018 Feb 21. doi: 10.1038/s41419-018-0346-y

PMCID:: PMC5833869

Abstract Article PDF–3.3M

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