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Items: 1 to 20 of 31

1.
Circadian activities of the brain MNK‐eIF4E signalling axis contribute to diurnal rhythms of some cognitive functions
Dong Liu, Jin Li, Hao Lin, Ethan Lorsung, Nam Le, Rubal Singla, Abhishek Mishra, Rikiro Fukunaga, Ruifeng Cao
Eur J Neurosci. 2022 Jul; 56(1): 3553–3569. Published online 2022 May 7. doi: 10.1111/ejn.15678
PMCID:
PMC9477079
AbstractArticlePDF–40M
2.
MiR‐223‐3p alleviates trigeminal neuropathic pain in the male mouse by targeting MKNK2 and MAPK/ERK signaling
Bixia Huang, Shaoyong Guo, Yipan Zhang, Pengxing Lin, Changgui Lin, Meixia Chen, Shengyin Zhu, Liyu Huang, Junwei He, Lingfeng Zhang, Yanping Zheng, Zhipeng Wen
Brain Behav. 2022 Jul; 12(7): e2634. Published online 2022 May 24. doi: 10.1002/brb3.2634
PMCID:
PMC9304854
AbstractArticlePDF–1.1M
3.
Inhibiting the MNK1/2-eIF4E axis impairs melanoma phenotype switching and potentiates antitumor immune responses
Fan Huang, Christophe Gonçalves, Margarita Bartish, Joelle Rémy-Sarrazin, Mark E. Issa, Brendan Cordeiro, Qianyu Guo, Audrey Emond, Mikhael Attias, William Yang, Dany Plourde, Jie Su, Marina Godoy Gimeno, Yao Zhan, Alba Galán, Tomasz Rzymski, Milena Mazan, Magdalena Masiejczyk, Jacek Faber, Elie Khoury, Alexandre Benoit, Natascha Gagnon, David Dankort, Fabrice Journe, Ghanem E. Ghanem, Connie M. Krawczyk, H. Uri Saragovi, Ciriaco A. Piccirillo, Nahum Sonenberg, Ivan Topisirovic, Christopher E. Rudd, Wilson H. Miller, Jr., Sonia V. del Rincón
J Clin Invest. 2021 Apr 15; 131(8): e140752. Published online 2021 Apr 15. doi: 10.1172/JCI140752
Correction in:
J Clin Invest. 2024 May 1; 134(9): e181575.
PMCID:
PMC8262472
AbstractArticlePDF–12M
4.
MNK2 governs the macrophage antiinflammatory phenotype
Margarita Bartish, Dongmei Tong, Yangxun Pan, Majken Wallerius, Hui Liu, Johannes Ristau, Sabrina de Souza Ferreira, Tatjana Wallmann, Vincent van Hoef, Laia Masvidal, Thomas Kerzel, Anne-Laure Joly, Christophe Goncalves, Samuel E. J. Preston, Talin Ebrahimian, Christina Seitz, Jonas Bergh, Kristian Pietras, Stephanie Lehoux, Luigi Naldini, John Andersson, Mario Leonardo Squadrito, Sonia V. del Rincón, Ola Larsson, Charlotte Rolny
Proc Natl Acad Sci U S A. 2020 Nov 3; 117(44): 27556–27565. Published online 2020 Oct 19. doi: 10.1073/pnas.1920377117
PMCID:
PMC7959504
AbstractArticlePDF–3.8M
5.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
6.
Disabling MNK protein kinases promotes oxidative metabolism and protects against diet-induced obesity
Lauren Y. Sandeman, Wan Xian Kang, Xuemin Wang, Kirk B. Jensen, Derick Wong, Tao Bo, Ling Gao, Jiajun Zhao, Christopher D. Byrne, Amanda J. Page, Christopher G. Proud
Mol Metab. 2020 Dec; 42: 101054. Published online 2020 Jul 23. doi: 10.1016/j.molmet.2020.101054
PMCID:
PMC7476876
AbstractArticlePDF–1.4M
7.
Translational control of depression-like behavior via phosphorylation of eukaryotic translation initiation factor 4E
Argel Aguilar-Valles, Nabila Haji, Danilo De Gregorio, Edna Matta-Camacho, Mohammad J. Eslamizade, Jelena Popic, Vijendra Sharma, Ruifeng Cao, Christoph Rummel, Arnaud Tanti, Shane Wiebe, Nicolas Nuñez, Stefano Comai, Robert Nadon, Giamal Luheshi, Naguib Mechawar, Gustavo Turecki, Jean-Claude Lacaille, Gabriella Gobbi, Nahum Sonenberg
Nat Commun. 2018; 9: 2459. Published online 2018 Jun 25. doi: 10.1038/s41467-018-04883-5
PMCID:
PMC6018502
AbstractArticlePDF–2.2M
8.
The MNK–eIF4E Signaling Axis Contributes to Injury-Induced Nociceptive Plasticity and the Development of Chronic Pain
Jamie K. Moy, Arkady Khoutorsky, Marina N. Asiedu, Bryan J. Black, Jasper L. Kuhn, Paulino Barragán-Iglesias, Salim Megat, Michael D. Burton, Carolina C. Burgos-Vega, Ohannes K. Melemedjian, Scott Boitano, Josef Vagner, Christos G. Gkogkas, Joseph J. Pancrazio, Jeffrey S. Mogil, Gregory Dussor, Nahum Sonenberg, Theodore J. Price
J Neurosci. 2017 Aug 2; 37(31): 7481–7499. doi: 10.1523/JNEUROSCI.0220-17.2017
PMCID:
PMC5546114
AbstractArticlePDF–5.3M
9.
Mycobacterium tuberculosis subverts negative regulatory pathways in human macrophages to drive immunopathology
Patience T. Brace, Liku B. Tezera, Magdalena K. Bielecka, Toby Mellows, Diana Garay, Shuye Tian, Lucinda Rand, Justin Green, Sanjay Jogai, Andrew J. Steele, Timothy M. Millar, Tilman Sanchez-Elsner, Jon S. Friedland, Christopher G. Proud, Paul T. Elkington
PLoS Pathog. 2017 Jun; 13(6): e1006367. Published online 2017 Jun 1. doi: 10.1371/journal.ppat.1006367
PMCID:
PMC5453634
AbstractArticlePDF–9.5M
10.
MNK1 and MNK2 mediate adverse effects of high-fat feeding in distinct ways
C. E. J. Moore, J. Pickford, F. R. Cagampang, R. L. Stead, S. Tian, X. Zhao, X. Tang, C. D. Byrne, C. G. Proud
Sci Rep. 2016; 6: 23476. Published online 2016 Apr 18. doi: 10.1038/srep23476
PMCID:
PMC4834573
AbstractArticlePDF–2.1M
11.
BDNF Stimulation of Protein Synthesis in Cortical Neurons Requires the MAP Kinase-Interacting Kinase MNK1
Maja Genheden, Justin W. Kenney, Harvey E. Johnston, Antigoni Manousopoulou, Spiros D. Garbis, Christopher G. Proud
J Neurosci. 2015 Jan 21; 35(3): 972–984. doi: 10.1523/JNEUROSCI.2641-14.2015
PMCID:
PMC4300335
AbstractArticlePDF–797K
12.
Pharmacogenetic Inhibition of eIF4E-Dependent Mmp9 mRNA Translation Reverses Fragile X Syndrome-like Phenotypes
Christos G. Gkogkas, Arkady Khoutorsky, Ruifeng Cao, Seyed Mehdi Jafarnejad, Masha Prager-Khoutorsky, Nikolaos Giannakas, Archontia Kaminari, Apostolia Fragkouli, Karim Nader, Theodore J. Price, Bruce W. Konicek, Jeremy R. Graff, Athina K. Tzinia, Jean-Claude Lacaille, Nahum Sonenberg
Cell Rep. Author manuscript; available in PMC 2015 Jan 14.
Published in final edited form as: Cell Rep. 2014 Dec 11; 9(5): 1742–1755. Published online 2014 Nov 26. doi: 10.1016/j.celrep.2014.10.064
PMCID:
PMC4294557
AbstractArticlePDF–1.9M
13.
Mnk kinase pathway: Cellular functions and biological outcomes
Sonali Joshi, Leonidas C Platanias
World J Biol Chem. 2014 Aug 26; 5(3): 321–333. Published online 2014 Aug 26. doi: 10.4331/wjbc.v5.i3.321
PMCID:
PMC4160526
AbstractArticlePDF–1.2M
14.
Translational control of the activation of transcription factor NF-κB and production of type I interferon by phosphorylation of the translation factor eIF4E
Barbara Herdy, Maritza Jaramillo, Yuri V Svitkin, Amy B Rosenfeld, Mariko Kobayashi, Derek Walsh, Tommy Alain, Polen Sean, Nathaniel Robichaud, Ivan Topisirovic, Luc Furic, Ryan J O Dowling, Annie Sylvestre, Liwei Rong, Rodney Colina, Mauro Costa-Mattioli, Jörg H Fritz, Martin Olivier, Earl Brown, Ian Mohr, Nahum Sonenberg
Nat Immunol. Author manuscript; available in PMC 2014 May 24.
Published in final edited form as: Nat Immunol. 2012 Jun; 13(6): 543–550. Published online 2012 Apr 29. doi: 10.1038/ni.2291
PMCID:
PMC4032494
AbstractArticlePDF–2.1M
15.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
16.
Mnk1 and 2 are dispensable for T-cell development and activation but important for the pathogenesis of experimental autoimmune encephalitis
Balachandra K Gorentla, Sruti Krishna, Jinwook Shin, Makoto Inoue, Mari L. Shinohara, Jason M. Grayson, Rikiro Fukunaga, Xiao-Ping Zhong
J Immunol. Author manuscript; available in PMC 2014 Feb 1.
Published in final edited form as: J Immunol. 2013 Feb 1; 190(3): 1026–1037. Published online 2012 Dec 26. doi: 10.4049/jimmunol.1200026
PMCID:
PMC3552100
AbstractArticlePDF–2.3M
17.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
18.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
19.
eIF4E phosphorylation promotes tumorigenesis and is associated with prostate cancer progression
Luc Furic, Liwei Rong, Ola Larsson, Ismaël Hervé Koumakpayi, Kaori Yoshida, Andrea Brueschke, Emmanuel Petroulakis, Nathaniel Robichaud, Michael Pollak, Louis A. Gaboury, Pier Paolo Pandolfi, Fred Saad, Nahum Sonenberg
Proc Natl Acad Sci U S A. 2010 Aug 10; 107(32): 14134–14139. Published online 2010 Aug 2. doi: 10.1073/pnas.1005320107
PMCID:
PMC2922605
AbstractArticlePDF–1.5M
20.
Combined deficiency for MAP kinase-interacting kinase 1 and 2 (Mnk1 and Mnk2) delays tumor development
Takeshi Ueda, Masato Sasaki, Andrew J. Elia, Iok In Christine Chio, Koichi Hamada, Rikiro Fukunaga, Tak W. Mak
Proc Natl Acad Sci U S A. 2010 Aug 10; 107(32): 13984–13990. Published online 2010 Aug 2. doi: 10.1073/pnas.1008136107
PMCID:
PMC2922567
AbstractArticlePDF–1.4M

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