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Select item 113818761.

N6-methyladenosine triggers renal fibrosis via enhancing translation and stability of ZEB2 mRNA

Yating Cai, Jiawang Zhou, Abai Xu, Jinchang Huang, Haisheng Zhang, Guoyou Xie, Ke Zhong, You Wu, Pengfei Ye, Hongsheng Wang, Hongxin Niu

J Biol Chem. 2024 Sep; 300(9): 107598. Published online 2024 Jul 24. doi: 10.1016/j.jbc.2024.107598

PMCID:: PMC11381876

Abstract Article PDF–6.2M

Select item 111137942.

ZEB2-transgene expression in the epidermis compromises the integrity of the epidermal barrier through the repression of different tight junction proteins

Marianthi N. Tatari, Bram De Craene, Bieke Soen, Joachim Taminau, Petra Vermassen, Steven Goossens, Katharina Haigh, Silvia Cazzola, Jo Lambert, Danny Huylebroeck, Jody J. Haigh, Geert Berx

Cell Mol Life Sci. 2014 Sep; 71(18): 3599–3609. Published online 2014 Feb 27. doi: 10.1007/s00018-014-1589-0

PMCID:: PMC11113794

Abstract Article PDF–1.6M

Select item 109017393.

A single-cell time-lapse of mouse prenatal development from gastrula to birth

Chengxiang Qiu, Beth K. Martin, Ian C. Welsh, Riza M. Daza, Truc-Mai Le, Xingfan Huang, Eva K. Nichols, Megan L. Taylor, Olivia Fulton, Diana R. O’Day, Anne Roshella Gomes, Saskia Ilcisin, Sanjay Srivatsan, Xinxian Deng, Christine M. Disteche, William Stafford Noble, Nobuhiko Hamazaki, Cecilia B. Moens, David Kimelman, Junyue Cao, Alexander F. Schier, Malte Spielmann, Stephen A. Murray, Cole Trapnell, Jay Shendure

Nature. 2024; 626(8001): 1084–1093. Published online 2024 Feb 14. doi: 10.1038/s41586-024-07069-w

PMCID:: PMC10901739

Abstract Article PDF–63M

Select item 108424174.

CD62L expression marks a functionally distinct subset of memory B cells

Christopher H. Hanson, Brittany Henry, Pradhnesh Andhare, Frank J. Lin, Haley Pak, Jackson S. Turner, Lucas J. Adams, Tom Liu, Daved H. Fremont, Ali H. Ellebedy, Brian J. Laidlaw

Cell Rep. Author manuscript; available in PMC 2024 Feb 5.

Published in final edited form as: Cell Rep. 2023 Dec 26; 42(12): 113542. Published online 2023 Dec 5. doi: 10.1016/j.celrep.2023.113542

PMCID:: PMC10842417

Abstract Article PDF–1.3M

Select item 106555555.

The adaptive antioxidant response during fasting-induced muscle atrophy is oppositely regulated by ZEB1 and ZEB2

Chiara Ninfali, Marlies Cortés, M. C. Martínez-Campanario, Verónica Domínguez, Lu Han, Ester Tobías, Anna Esteve-Codina, Carlos Enrich, Belén Pintado, Gloria Garrabou, Antonio Postigo

Proc Natl Acad Sci U S A. 2023 Nov 14; 120(46): e2301120120. Published online 2023 Nov 10. doi: 10.1073/pnas.2301120120

PMCID:: PMC10655555

Abstract Article PDF–9.6M

Select item 106161176.

Zeb2 regulates differentiation of long-lived effector of invariant natural killer T cells

Tomonori Iyoda, Kanako Shimizu, Takaho Endo, Takashi Watanabe, Ichiro Taniuchi, Honoka Aoshima, Mikiko Satoh, Hiroshi Nakazato, Satoru Yamasaki, Shin-ichiro Fujii

Commun Biol. 2023; 6: 1070. Published online 2023 Oct 30. doi: 10.1038/s42003-023-05421-w

PMCID:: PMC10616117

Abstract Article PDF–3.1M

Select item 103582837.

Ablation of cDC2 development by triple mutations within the Zeb2 enhancer

Tian-Tian Liu, Sunkyung Kim, Pritesh Desai, Do-Hyun Kim, Xiao Huang, Stephen T. Ferris, Renee Wu, Feiya Ou, Takeshi Egawa, Steven J. Van Dyken, Michael S. Diamond, Peter F. Johnson, Masato Kubo, Theresa L. Murphy, Kenneth M. Murphy

Nature. Author manuscript; available in PMC 2023 Jul 20.

Published in final edited form as: Nature. 2022 Jul; 607(7917): 142–148. Published online 2022 Jun 22. doi: 10.1038/s41586-022-04866-z

PMCID:: PMC10358283

Abstract Article PDF–3.8M

Select item 103361518.

IL-6 selectively suppresses cDC1 specification via C/EBPβ

Sunkyung Kim, Jing Chen, Suin Jo, Feiya Ou, Stephen T. Ferris, Tian-Tian Liu, Ray A. Ohara, David A. Anderson, III, Renee Wu, Michael Y. Chen, William E. Gillanders, William E. Gillanders, Theresa L. Murphy, Kenneth M. Murphy

J Exp Med. 2023 Oct 2; 220(10): e20221757. Published online 2023 Jul 11. doi: 10.1084/jem.20221757

PMCID:: PMC10336151

Abstract Article PDF–7.0M

Select item 102536679.

The Midbrain Preisthmus: A Poorly Known Effect of the Isthmic Organizer

Luis Puelles, Matias Hidalgo-Sánchez

Int J Mol Sci. 2023 Jun; 24(11): 9769. Published online 2023 Jun 5. doi: 10.3390/ijms24119769

PMCID:: PMC10253667

Abstract Article PDF–6.8M

Select item 1020902710.

miR-147a targets ZEB2 to regulate ox-LDL-induced monocyte adherence to HUVECs, atherosclerotic plaque formation, and stability in atherosclerosis

Fengying Chen, Yuzhen Ning, Jingying Liu, Ming Lian, Juanjuan Wang, Hongwei Dan

J Biol Chem. 2023 Jun; 299(6): 104657. Published online 2023 Mar 29. doi: 10.1016/j.jbc.2023.104657

PMCID:: PMC10209027

Abstract Article PDF–5.9M

Select item 1009148511.

Pituitary Stem Cell Regulation by Zeb2 and BMP Signaling

Amanda H Winningham, Sally A Camper

Endocrinology. 2023 Mar; 164(3): bqad016. Published online 2023 Jan 23. doi: 10.1210/endocr/bqad016

PMCID:: PMC10091485

Abstract Article

Select item 1004807112.

Zeb2 DNA-Binding Sites in Neuroprogenitor Cells Reveal Autoregulation and Affirm Neurodevelopmental Defects, Including in Mowat-Wilson Syndrome

Judith C. Birkhoff, Anne L. Korporaal, Rutger W. W. Brouwer, Karol Nowosad, Claudia Milazzo, Lidia Mouratidou, Mirjam C. G. N. van den Hout, Wilfred F. J. van IJcken, Danny Huylebroeck, Andrea Conidi

Genes (Basel) 2023 Mar; 14(3): 629. Published online 2023 Mar 2. doi: 10.3390/genes14030629

PMCID:: PMC10048071

Abstract Article PDF–3.9M

Select item 987008913.

ZEB2 controls kidney stromal progenitor differentiation and inhibits abnormal myofibroblast expansion and kidney fibrosis

Sudhir Kumar, Xueping Fan, Hila Milo Rasouly, Richa Sharma, David J. Salant, Weining Lu

JCI Insight. 2023 Jan 10; 8(1): e158418. Published online 2023 Jan 10. doi: 10.1172/jci.insight.158418

PMCID:: PMC9870089

Abstract Article PDF–8.1M

Select item 968444814.

TBX1 targets the miR-200–ZEB2 axis to induce epithelial differentiation and inhibit stem cell properties

Noriko Funato, Hiromi Yanagisawa

Sci Rep. 2022; 12: 20188. Published online 2022 Nov 23. doi: 10.1038/s41598-022-24604-9

PMCID:: PMC9684448

Abstract Article PDF–4.7M

Select item 916965115.

Single cell enhancer activity distinguishes GABAergic and cholinergic lineages in embryonic mouse basal ganglia

Linda Su-Feher, Anna N. Rubin, Shanni N. Silberberg, Rinaldo Catta-Preta, Kenneth J. Lim, Athena R. Ypsilanti, Iva Zdilar, Christopher S. McGinnis, Gabriel L. McKinsey, Thomas E. Rubino, Jr., Michael J. Hawrylycz, Carol Thompson, Zev J. Gartner, Luis Puelles, Hongkui Zeng, John L. R. Rubenstein, Alex S. Nord

Proc Natl Acad Sci U S A. 2022 Apr 12; 119(15): e2108760119. Published online 2022 Apr 4. doi: 10.1073/pnas.2108760119

PMCID:: PMC9169651

Abstract Article PDF–3.9M

Select item 895345416.

Endothelial Zeb2 preserves the hepatic angioarchitecture and protects against liver fibrosis

Willeke de Haan, Wouter Dheedene, Katerina Apelt, Sofiane Décombas-Deschamps, Stefan Vinckier, Stefaan Verhulst, Andrea Conidi, Thomas Deffieux, Michael W Staring, Petra Vandervoort, Ellen Caluwé, Marleen Lox, Inge Mannaerts, Tsuyoshi Takagi, Joris Jaekers, Geert Berx, Jody Haigh, Baki Topal, An Zwijsen, Yujiro Higashi, Leo A van Grunsven, Wilfred F J van IJcken, Eskeatnaf Mulugeta, Mickael Tanter, Franck P G Lebrin, Danny Huylebroeck, Aernout Luttun

Cardiovasc Res. 2022 Apr; 118(5): 1262–1275. Published online 2021 Apr 28. doi: 10.1093/cvr/cvab148

PMCID:: PMC8953454

Abstract Article PDF–2.5M

Select item 876331717.

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1–CoREST interactome during embryonic stem cell differentiation

Claire E. Barnes, David M. English, Megan Broderick, Mark O. Collins, Shaun M. Cowley

Mol Omics. 2022 Jan 17; 18(1): 31–44. Published online 2021 Oct 14. doi: 10.1039/d1mo00236h

PMCID:: PMC8763317

Abstract Article

Select item 863854618.

Zeb2 regulates the balance between retinal interneurons and Muller glia by inhibition of BMP–Smad signaling

Yotam Menuchin-Lasowski, Bar Dagan, Andrea Conidi, Mazal Cohen-Gulkar, Ahuvit David, Marcelo Ehrlich, Pazit Oren Giladi, Brian S. Clark, Seth Blackshaw, Keren Shapira, Danny Huylebroeck, Yoav Henis, Ruth Ashery-Padan

Dev Biol. Author manuscript; available in PMC 2021 Dec 2.

Published in final edited form as: Dev Biol. 2020 Dec 1; 468(1-2): 80–92. Published online 2020 Sep 17. doi: 10.1016/j.ydbio.2020.09.006

PMCID:: PMC8638546

Abstract Article PDF–2.5M

Select item 849566319.

Two sequential activation modules control the differentiation of protective T helper-1 (Th1) cells

Peter D. Krueger, Michael F. Goldberg, Sung-Wook Hong, Kevin C. Osum, Ryan A. Langlois, Dmitri I. Kotov, Thamotharampillai Dileepan, Marc K. Jenkins

Immunity. Author manuscript; available in PMC 2022 Apr 13.

Published in final edited form as: Immunity. 2021 Apr 13; 54(4): 687–701.e4. Published online 2021 Mar 26. doi: 10.1016/j.immuni.2021.03.006

PMCID:: PMC8495663

Abstract Article PDF–2.9M

Select item 848972620.

Interplay between the EMT transcription factors ZEB1 and ZEB2 regulates hematopoietic stem and progenitor cell differentiation and hematopoietic lineage fidelity

Jueqiong Wang, Carlos Farkas, Aissa Benyoucef, Catherine Carmichael, Katharina Haigh, Nick Wong, Danny Huylebroeck, Marc P. Stemmler, Simone Brabletz, Thomas Brabletz, Christian M. Nefzger, Steven Goossens, Geert Berx, Jose M. Polo, Jody J. Haigh

PLoS Biol. 2021 Sep; 19(9): e3001394. Published online 2021 Sep 22. doi: 10.1371/journal.pbio.3001394

PMCID:: PMC8489726

Abstract Article PDF–2.7M

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