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Items: 1 to 20 of 34

1.
Altered dNTP pools accelerate tumor formation in mice
Phong Tran, Pradeep Mishra, Leonard G Williams, Roman Moskalenko, Sushma Sharma, Anna Karin Nilsson, Danielle L Watt, Pernilla Andersson, Anders Bergh, Zachary F Pursell, Andrei Chabes
Nucleic Acids Res. 2024 Nov 11; 52(20): 12475–12486. Published online 2024 Oct 3. doi: 10.1093/nar/gkae843
PMCID:
PMC11551754
AbstractArticlePDF–1.3M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
A missense mutation in RRM1 contributes to animal tameness
Mingle Dou, Ming Li, Zhuqing Zheng, Qiuming Chen, Yongji Wu, Jinxin Wang, Huiquan Shan, Fei Wang, Xuelei Dai, Yunjia Li, Zhirui Yang, Guanghui Tan, Funong Luo, Lei Chen, Yun Stone Shi, Jiang Wei Wu, Xiong-Jian Luo, Hojjat Asadollahpour Nanaei, Zhannur Niyazbekova, Guojie Zhang, Wen Wang, Shanting Zhao, Wenxin Zheng, Xihong Wang, Yu Jiang
Sci Adv. 2023 Jun; 9(25): eadf4068. Published online 2023 Jun 23. doi: 10.1126/sciadv.adf4068
PMCID:
PMC10289655
AbstractArticlePDF–1.6M
4.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
5.
An Immunocompetent Mouse Model of HPV16(+) Head and Neck Squamous Cell Carcinoma
Miranda B. Carper, Scott Troutman, Bethany L. Wagner, Kevin M. Byrd, Sara R. Selitsky, Kshitij Parag-Sharma, Erin C. Henry, Weimin Li, Joel S. Parker, Stephanie A. Montgomery, John L. Cleveland, Scott E. Williams, Joseph L. Kissil, David N. Hayes, Antonio L. Amelio
Cell Rep. Author manuscript; available in PMC 2019 Nov 21.
Published in final edited form as: Cell Rep. 2019 Nov 5; 29(6): 1660–1674.e7. doi: 10.1016/j.celrep.2019.10.005
PMCID:
PMC6870917
AbstractArticlePDF–3.1M
6.
Asxl1 exerts an antiproliferative effect on mouse lung maturation via epigenetic repression of the E2f1-Nmyc axis
Seungtae Moon, Sun-Kyoung Im, Nackhyoung Kim, Hyesook Youn, Ui-Hyun Park, Joo-Yeon Kim, A.-Reum Kim, So-Jung An, Ji-Hoon Kim, Woong Sun, Jin-Taek Hwang, Eun-Joo Kim, Soo-Jong Um
Cell Death Dis. 2018 Nov; 9(11): 1118. Published online 2018 Nov 2. doi: 10.1038/s41419-018-1171-z
PMCID:
PMC6215009
AbstractArticlePDF–2.7M
7.
The E3 Ubiquitin Ligases, HUWE1 and NEDD4-1, Are Involved in the Post-translational Regulation of the ABCG1 and ABCG4 Lipid Transporters
Shereen M. Aleidi, Vicky Howe, Laura J. Sharpe, Alryel Yang, Geetha Rao, Andrew J. Brown, Ingrid C. Gelissen
J Biol Chem. 2015 Oct 2; 290(40): 24604–24613. Published online 2015 Aug 20. doi: 10.1074/jbc.M115.675579
PMCID:
PMC4591838
AbstractArticlePDF–1.2M
8.
A Single Conserved Residue Mediates Binding of the Ribonucleotide Reductase Catalytic Subunit RRM1 to RRM2 and Is Essential for Mouse Development
Julia Specks, Emilio Lecona, Andrés J. Lopez-Contreras, Oscar Fernandez-Capetillo
Mol Cell Biol. 2015 Sep; 35(17): 2910–2917. Prepublished online 2015 Jun 15. Published online 2015 Aug 4. doi: 10.1128/MCB.00475-15
PMCID:
PMC4525308
AbstractArticlePDF–1.1M
9.
Transgenically-expressed secretoglobin 3A2 accelerates resolution of bleomycin-induced pulmonary fibrosis in mice
Yan Cai, Mitsuhiro Yoneda, Takeshi Tomita, Reiko Kurotani, Minoru Okamoto, Taketomo Kido, Hiroyuki Abe, Wayne Mitzner, Arjun Guha, Shioko Kimura
BMC Pulm Med. 2015; 15: 72. Published online 2015 Jul 16. doi: 10.1186/s12890-015-0065-4
PMCID:
PMC4504078
AbstractArticlePDF–2.0M
10.
The Central Role of EED in the Orchestration of Polycomb Group Complexes
Qi Cao, Xiaoju Wang, Meng Zhao, Rendong Yang, Rohit Malik, Yuanyuan Qiao, Anton Poliakov, Anastasia K. Yocum, Yong Li, Wei Chen, Xuhong Cao, Xia Jiang, Arun Dahiya, Clair Harris, Felix Y. Feng, Sundeep Kalantry, Zhaohui S. Qin, Saravana M. Dhanasekaran, Arul M. Chinnaiyan
Nat Commun. Author manuscript; available in PMC 2014 Jul 24.
Published in final edited form as: Nat Commun. 2014; 5: 3127. doi: 10.1038/ncomms4127
PMCID:
PMC4073494
AbstractArticlePDF–2.1M
11.
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson
Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977
PMCID:
PMC3964955
AbstractArticlePDF–5.7M
12.
Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates
Jeremy A. Miller, Jason Nathanson, Daniel Franjic, Sungbo Shim, Rachel A. Dalley, Sheila Shapouri, Kimberly A. Smith, Susan M. Sunkin, Amy Bernard, Jeffrey L. Bennett, Chang-Kyu Lee, Michael J. Hawrylycz, Allan R. Jones, David G. Amaral, Nenad Sestan, Fred H. Gage, Ed S. Lein
Development. 2013 Nov 15; 140(22): 4633–4644. doi: 10.1242/dev.097212
PMCID:
PMC3817946
AbstractArticle
13.
Phosphoinositide-specific Phospholipase C β 1b (PI-PLCβ1b) Interactome: Affinity Purification-Mass Spectrometry Analysis of PI-PLCβ1b with Nuclear Protein
Manuela Piazzi, William L. Blalock, Alberto Bavelloni, Irene Faenza, Antonietta D'Angelo, Nadir M. Maraldi, Lucio Cocco
Mol Cell Proteomics. 2013 Aug; 12(8): 2220–2235. Published online 2013 May 9. doi: 10.1074/mcp.M113.029686
PMCID:
PMC3734581
AbstractArticlePDF–1.9M
14.
Silencing of ribonucleotide reductase subunit M1 potentiates the antitumor activity of gemcitabine in resistant cancer cells
Piyanuch Wonganan, Woon-Gye Chung, Saijie Zhu, Kaoru Kiguchi, John DiGiovanni, Zhengrong Cui
Cancer Biol Ther. 2012 Aug 1; 13(10): 908–914. Published online 2012 Aug 1. doi: 10.4161/cbt.20843
PMCID:
PMC3679115
AbstractArticlePDF–685K
15.
Transgenic overexpression of ribonucleotide reductase improves cardiac performance
Sarah G. Nowakowski, Stephen C. Kolwicz, Frederick Steven Korte, Zhaoxiong Luo, Jacqueline N. Robinson-Hamm, Jennifer L. Page, Frank Brozovich, Robert S. Weiss, Rong Tian, Charles E. Murry, Michael Regnier
Proc Natl Acad Sci U S A. 2013 Apr 9; 110(15): 6187–6192. Published online 2013 Mar 25. doi: 10.1073/pnas.1220693110
PMCID:
PMC3625337
AbstractArticlePDF–332K
16.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
17.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
18.
Ribonucleotide reductase is not limiting for mitochondrial DNA copy number in mice
Emil Ylikallio, Jennifer L. Page, Xia Xu, Milla Lampinen, Gerold Bepler, Tomomi Ide, Henna Tyynismaa, Robert S. Weiss, Anu Suomalainen
Nucleic Acids Res. 2010 Dec; 38(22): 8208–8218. Published online 2010 Aug 19. doi: 10.1093/nar/gkq735
PMCID:
PMC3001089
AbstractArticlePDF–4.3M
19.
Essential role of Tip60-dependent recruitment of ribonucleotide reductase at DNA damage sites in DNA repair during G1 phase
Hiroyuki Niida, Yuko Katsuno, Misuzu Sengoku, Midori Shimada, Megumi Yukawa, Masae Ikura, Tsuyoshi Ikura, Kazuteru Kohno, Hiroki Shima, Hidekazu Suzuki, Satoshi Tashiro, Makoto Nakanishi
Genes Dev. 2010 Feb 15; 24(4): 333–338. doi: 10.1101/gad.1863810
PMCID:
PMC2816732
AbstractArticlePDF–593K
20.
Molecular Mechanisms of Thioredoxin and Glutaredoxin as Hydrogen Donors for Mammalian S Phase Ribonucleotide Reductase
Farnaz Zahedi Avval, Arne Holmgren
J Biol Chem. 2009 Mar 27; 284(13): 8233–8240. doi: 10.1074/jbc.M809338200
PMCID:
PMC2659180
AbstractArticlePDF–396K

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