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Items: 1 to 20 of 151

1.
An association between elevated telomerase reverse transcriptase expression and the immune tolerance disruption of dendritic cells
Xuejie Xu, Lihua Mo, Yun Liao, Kaitlyn Song Zhang, Hanqing Zhang, Le Liu, Yu Liu, Aifa Tang, Pingchang Yang, Xiaoyu Liu
Cell Commun Signal. 2024; 22: 284. Published online 2024 May 23. doi: 10.1186/s12964-024-01650-6
PMCID:
PMC11112790
AbstractArticlePDF–6.7M
2.
TERT mediates the U‐shape of glucocorticoids effects in modulation of hippocampal neural stem cells and associated brain function
Meng‐Ying Liu, Yixin Fan, Ningjie Ni, Tao Yu, Zhiyuan Mao, Hanyu Huang, Jing Zhang, Yulin Tang, Hongliang He, Fan Meng, Yongping You, Qi‐Gang Zhou
CNS Neurosci Ther. 2024 Feb; 30(2): e14577. Published online 2024 Feb 7. doi: 10.1111/cns.14577
PMCID:
PMC10850922
AbstractArticlePDF–39M
3.
The Wnt/β-catenin signaling pathway inhibits osteoporosis by regulating the expression of TERT: an in vivo and in vitro study
Yuanqing Cai, Huijun Sun, Xingyu Song, Jianyu Zhao, Dong Xu, Mozhen Liu
Aging (Albany NY) 2023 Oct 31; 15(20): 11471–11488. Published online 2023 Oct 19. doi: 10.18632/aging.205136
PMCID:
PMC10637795
AbstractArticlePDF–2.6M
4.
TERT accelerates BRAF mutant–induced thyroid cancer dedifferentiation and progression by regulating ribosome biogenesis
Pengcheng Yu, Ning Qu, Rui Zhu, Jiaqian Hu, Peizhen Han, Jiahao Wu, Licheng Tan, Hualei Gan, Cong He, Chuantao Fang, Yubin Lei, Jian Li, Chenxi He, Fei Lan, Xiao Shi, Wenjun Wei, Yu Wang, Qinghai Ji, Fa-Xing Yu, Yu-Long Wang
Sci Adv. 2023 Sep; 9(35): eadg7125. Published online 2023 Aug 30. doi: 10.1126/sciadv.adg7125
PMCID:
PMC10468137
AbstractArticlePDF–3.1M
5.
Image-based quantification of histological features as a function of spatial location using the Tissue Positioning System
Ruichen Rong, Yonglong Wei, Lin Li, Tao Wang, Hao Zhu, Guanghua Xiao, Yunguan Wang
eBioMedicine. 2023 Aug; 94: 104698. Published online 2023 Jul 13. doi: 10.1016/j.ebiom.2023.104698
PMCID:
PMC10365985
AbstractArticlePDF–5.4M
6.
Telomerase deficiency and dysfunctional telomeres in the lung tumor microenvironment impair tumor progression in NSCLC mouse models and patient-derived xenografts
Sergio Piñeiro-Hermida, Giuseppe Bosso, Raúl Sánchez-Vázquez, Paula Martínez, Maria A. Blasco
Cell Death Differ. 2023 Jun; 30(6): 1585–1600. Published online 2023 Apr 21. doi: 10.1038/s41418-023-01149-6
PMCID:
PMC10244372
AbstractArticlePDF–8.4M
7.
Prenatal stress modulates HPA axis homeostasis of offspring through dentate TERT independently of glucocorticoids receptor
Meng-Ying Liu, Lu-Lu Wei, Xian-Hui Zhu, Hua-Chen Ding, Xiang-Hu Liu, Huan Li, Yuan-Yuan Li, Zhou Han, Lian-Di Li, Zi-Wei Du, Ya-Ping Zhou, Jing Zhang, Fan Meng, Yu-Lin Tang, Xiao Liu, Chun Wang, Qi-Gang Zhou
Mol Psychiatry. 2023; 28(3): 1383–1395. Published online 2022 Dec 8. doi: 10.1038/s41380-022-01898-9
PMCID:
PMC10005958
AbstractArticlePDF–4.3M
8.
B7H3-dependent myeloid-derived suppressor cell recruitment and activation in pulmonary fibrosis
Tianju Liu, Francina Gonzalez De Los Santos, Andrew E. Rinke, Chuling Fang, Kevin R. Flaherty, Sem H. Phan
Front Immunol. 2022; 13: 901349. Published online 2022 Aug 15. doi: 10.3389/fimmu.2022.901349
PMCID:
PMC9420866
AbstractArticlePDF–10M
9.
Acinar cell clonal expansion in pancreas homeostasis and carcinogenesis
Patrick Neuhöfer, Caitlin M. Roake, Stewart J. Kim, Ryan J. Lu, Robert B. West, Gregory W. Charville, Steven E. Artandi
Nature. Author manuscript; available in PMC 2022 Aug 3.
Published in final edited form as: Nature. 2021 Sep; 597(7878): 715–719. Published online 2021 Sep 15. doi: 10.1038/s41586-021-03916-2
PMCID:
PMC9347609
AbstractArticlePDF–2.9M
10.
A mouse model for Li-Fraumeni-Like Syndrome with cardiac angiosarcomas associated to POT1 mutations
Paula Martínez, Raúl Sánchez-Vázquez, Iole Ferrara-Romeo, Rosa Serrano, Juana M. Flores, Maria A. Blasco
PLoS Genet. 2022 Jun; 18(6): e1010260. Published online 2022 Jun 21. doi: 10.1371/journal.pgen.1010260
PMCID:
PMC9212151
AbstractArticlePDF–3.4M
11.
Pulmonary Alveolar Stem Cell Senescence, Apoptosis, and Differentiation by p53-Dependent and -Independent Mechanisms in Telomerase-Deficient Mice
Kexiong Zhang, Lihui Wang, Xiaojing Hong, Hao Chen, Yao Shi, Yingying Liu, Jun Liu, Jun-Ping Liu
Cells. 2021 Nov; 10(11): 2892. Published online 2021 Oct 26. doi: 10.3390/cells10112892
PMCID:
PMC8616483
AbstractArticlePDF–2.8M
12.
Liver homeostasis is maintained by midlobular zone 2 hepatocytes
Yonglong Wei, Yunguan G. Wang, Yuemeng Jia, Lin Li, Jung Yoon, Shuyuan Zhang, Zixi Wang, Yu Zhang, Min Zhu, Tripti Sharma, Yu-Hsuan Lin, Meng-Hsiung Hsieh, Jeffrey H. Albrecht, Phuong T. Le, Clifford J. Rosen, Tao Wang, Hao Zhu
Science. Author manuscript; available in PMC 2021 Oct 7.
Published in final edited form as: Science. 2021 Feb 26; 371(6532): eabb1625. doi: 10.1126/science.abb1625
PMCID:
PMC8496420
AbstractArticlePDF–6.4M
13.
DNA-RNA Hybrid (R-Loop): From a Unified Picture of the Mammalian Telomere to the Genome-Wide Profile
Minoo Rassoulzadegan, Ali Sharifi-Zarchi, Leila Kianmehr
Cells. 2021 Jun; 10(6): 1556. Published online 2021 Jun 19. doi: 10.3390/cells10061556
PMCID:
PMC8233970
AbstractArticlePDF–3.3M
14.
Short and dysfunctional telomeres protect from allergen‐induced airway inflammation
Sergio Piñeiro‐Hermida, Paula Martínez, Maria A. Blasco
Aging Cell. 2021 May; 20(5): e13352. Published online 2021 May 4. doi: 10.1111/acel.13352
PMCID:
PMC8135011
AbstractArticlePDF–4.6M
15.
Telomerase expression marks transitional growth‐associated skeletal progenitor/stem cells
Diana L. Carlone, Rebecca D. Riba‐Wolman, Luke T. Deary, Alessio Tovaglieri, Lijie Jiang, Dana M. Ambruzs, Benjamin E. Mead, Manasvi S. Shah, Christopher J. Lengner, Rudolf Jaenisch, David T. Breault
Stem Cells. 2021 Mar; 39(3): 296–305. Published online 2021 Jan 13. doi: 10.1002/stem.3318
PMCID:
PMC7986156
AbstractArticlePDF–9.5M
16.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
17.
Re‐equilibration of imbalanced NAD metabolism ameliorates the impact of telomere dysfunction
Chongkui Sun, Kun Wang, Amanda J Stock, Yi Gong, Tyler G Demarest, Beimeng Yang, Neelam Giri, Lea Harrington, Blanche P Alter, Sharon A Savage, Vilhelm A Bohr, Yie Liu
EMBO J. 2020 Nov 2; 39(21): e103420. Published online 2020 Sep 16. doi: 10.15252/embj.2019103420
PMCID:
PMC7604620
AbstractArticlePDF–5.0M
18.
Telomere dysfunction activates YAP1 to drive tissue inflammation
Deepavali Chakravarti, Baoli Hu, Xizeng Mao, Asif Rashid, Jiexi Li, Jun Li, Wen-ting Liao, Elizabeth M. Whitley, Prasenjit Dey, Pingping Hou, Kyle A. LaBella, Andrew Chang, Guocan Wang, Denise J. Spring, Pingna Deng, Di Zhao, Xin Liang, Zhengdao Lan, Yiyun Lin, Sharmistha Sarkar, Christopher Terranova, Yonathan Lissanu Deribe, Sarah E. Blutt, Pablo Okhuysen, Jianhua Zhang, Eduardo Vilar, Ole Haagen Nielsen, Andrew Dupont, Mamoun Younes, Kalyani R. Patel, Noah F. Shroyer, Kunal Rai, Mary K. Estes, Y. Alan Wang, Alison A. Bertuch, Ronald A. DePinho
Nat Commun. 2020; 11: 4766. Published online 2020 Sep 21. doi: 10.1038/s41467-020-18420-w
PMCID:
PMC7505960
AbstractArticlePDF–2.3M
19.
BRD4 contributes to LPS-induced macrophage senescence and promotes progression of atherosclerosis-associated lipid uptake
Hui Wang, Haiping Fu, Ruigong Zhu, Xuan Wu, Xian Ji, Xuesong Li, Hong Jiang, Zhe Lin, Xin Tang, Shixiu Sun, Jiajing Chen, Xin Wang, Qingguo Li, Yong Ji, Hongshan Chen
Aging (Albany NY) 2020 May 31; 12(10): 9240–9259. Published online 2020 May 11. doi: 10.18632/aging.103200
PMCID:
PMC7288959
AbstractArticlePDF–2.5M
20.
Dichotomy between the transcriptomic landscape of naturally versus accelerated aged murine hearts
Federica De Majo, Jana-Charlotte Hegenbarth, Frank Rühle, Christian Bär, Thomas Thum, Martine de Boer, Dirk J. Duncker, Blanche Schroen, Anne-Sophie Armand, Monika Stoll, Leon J. De Windt
Sci Rep. 2020; 10: 8136. Published online 2020 May 18. doi: 10.1038/s41598-020-65115-9
PMCID:
PMC7235007
AbstractArticlePDF–5.4M

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