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Items: 1 to 20 of 100

1.
Inhibitory G proteins play multiple roles to polarize sensory hair cell morphogenesis
Amandine Jarysta, Abigail LD Tadenev, Matthew Day, Barry Krawchuk, Benjamin E Low, Michael V Wiles, Basile Tarchini
eLife. 2024; 12: RP88186. Published online 2024 Apr 23. doi: 10.7554/eLife.88186
PMCID:
PMC11037916
AbstractArticlePDF–8.9M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
The Schwann cell-specific G-protein Gαo (Gnao1) is a cell-intrinsic controller contributing to the regulation of myelination in peripheral nerve system
Jinghui Xu, Qianqian Peng, Jieyi Cai, Jianghong Shangguan, Wenfeng Su, Gang Chen, Hualin Sun, Changlai Zhu, Yun Gu
Acta Neuropathol Commun. 2024; 12: 24. Published online 2024 Feb 8. doi: 10.1186/s40478-024-01720-3
PMCID:
PMC10854112
AbstractArticlePDF–19M
4.
KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility
Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao
Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5
PMCID:
PMC10307852
AbstractArticlePDF–8.8M
5.
CRISPR/Cas9-generated mouse model with humanizing single-base substitution in the Gnao1 for safety studies of RNA therapeutics
Anna V. Polikarpova, Tatiana V. Egorova, Evgenii A. Lunev, Alexandra A. Tsitrina, Svetlana G. Vassilieva, Irina M. Savchenko, Yuliya Y. Silaeva, Alexey V. Deykin, Maryana V. Bardina
Front Genome Ed. 2023; 5: 1034720. Published online 2023 Apr 3. doi: 10.3389/fgeed.2023.1034720
PMCID:
PMC10106585
AbstractArticlePDF–2.8M
6.
Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub
Marc P. Forrest, Marc Dos Santos, Nicolas H. Piguel, Yi-Zhi Wang, Nicole A. Hawkins, Vikram A. Bagchi, Leonardo E. Dionisio, Sehyoun Yoon, Dina Simkin, Maria Dolores Martin-de-Saavedra, Ruoqi Gao, Katherine E. Horan, Alfred L. George, Jr., Mark S. LeDoux, Jennifer A. Kearney, Jeffrey N. Savas, Peter Penzes
Nat Commun. 2023; 14: 825. Published online 2023 Feb 17. doi: 10.1038/s41467-023-36087-x
PMCID:
PMC9938216
AbstractArticlePDF–5.3M
7.
Clustering of vomeronasal receptor genes is required for transcriptional stability but not for choice
Quentin Dietschi, Joël Tuberosa, Leon Fodoulian, Madlaina Boillat, Chenda Kan, Julien Codourey, Véronique Pauli, Paul Feinstein, Alan Carleton, Ivan Rodriguez
Sci Adv. 2022 Nov; 8(46): eabn7450. Published online 2022 Nov 16. doi: 10.1126/sciadv.abn7450
PMCID:
PMC9668312
AbstractArticlePDF–1.6M
8.
The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3
Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany
Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527
PMCID:
PMC9603860
AbstractArticlePDF–3.4M
9.
Inhibitory signaling in mammalian olfactory transduction potentially mediated by Gαo
Elizabeth A. Corey, Kirill Ukhanov, Yuriy V. Bobkov, Jeremy C. McIntyre, Jeffrey R. Martens, Barry W. Ache
Mol Cell Neurosci. Author manuscript; available in PMC 2022 May 2.
Published in final edited form as: Mol Cell Neurosci. 2021 Jan; 110: 103585. Published online 2020 Dec 25. doi: 10.1016/j.mcn.2020.103585
PMCID:
PMC9060814
AbstractArticlePDF–1.7M
10.
Mouse models characterize GNAO1 encephalopathy as a neurodevelopmental disorder leading to motor anomalies: from a severe G203R to a milder C215Y mutation
Denis Silachev, Alexey Koval, Mikhail Savitsky, Guru Padmasola, Charles Quairiaux, Fabrizio Thorel, Vladimir L. Katanaev
Acta Neuropathol Commun. 2022; 10: 9. Published online 2022 Jan 28. doi: 10.1186/s40478-022-01312-z
PMCID:
PMC8796625
AbstractArticlePDF–6.8M
11.
Mice Expressing Regulators of G protein Signaling–insensitive Gαo Define Roles of μ Opioid Receptor Gαo and Gαi Subunit Coupling in Inhibition of Presynaptic GABA Release
Courtney A. Bouchet, Kylie B. McPherson, Ming-hua Li, John R. Traynor, Susan L. Ingram
Mol Pharmacol. 2021 Sep; 100(3): 217–223. Published online 2021 Sep. doi: 10.1124/molpharm.121.000249
PMCID:
PMC8626785
AbstractArticlePDF–995K
12.
Cocaine Shifts Dopamine D2 Receptor Sensitivity to Gate Conditioned Behaviors
Sheng Gong, Nicholas Fayette, Jasper A Heinsbroek, Christopher P Ford
Neuron. Author manuscript; available in PMC 2022 Nov 3.
Published in final edited form as: Neuron. 2021 Nov 3; 109(21): 3421–3435.e5. Published online 2021 Sep 9. doi: 10.1016/j.neuron.2021.08.012
Correction in:
Neuron. 2022 Apr 6; 110(7): 1272.
PMCID:
PMC8571051
AbstractArticlePDF–3.0M
13.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
14.
Microtubules and Gαo-signaling modulate the preferential secretion of young insulin secretory granules in islet β cells via independent pathways
Ruiying Hu, Xiaodong Zhu, Mingyang Yuan, Kung-Hsien Ho, Irina Kaverina, Guoqiang Gu
PLoS One. 2021; 16(7): e0241939. Published online 2021 Jul 22. doi: 10.1371/journal.pone.0241939
PMCID:
PMC8297875
AbstractArticlePDF–4.4M
15.
Cellular Diversity and Differential Subcellular Localization of the G-Protein Gαo Subunit in the Mouse Cerebellum
Alberto Roldán-Sastre, Carolina Aguado, Alejandro Martín-Belmonte, Rocío Alfaro-Ruiz, Ana Esther Moreno-Martínez, Rafael Luján
Front Neuroanat. 2021; 15: 686279. Published online 2021 Jun 25. doi: 10.3389/fnana.2021.686279
PMCID:
PMC8267243
AbstractArticlePDF–7.0M
16.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
17.
Gαo is a major determinant of cAMP signaling in the pathophysiology of movement disorders
Brian S. Muntean, Ikuo Masuho, Maria Dao, Laurie P. Sutton, Stefano Zucca, Hideki Iwamoto, Dipak N. Patil, Dandan Wang, Lutz Birnbaumer, Randy D. Blakely, Brock Grill, Kirill A. Martemyanov
Cell Rep. Author manuscript; available in PMC 2021 Feb 24.
Published in final edited form as: Cell Rep. 2021 Feb 2; 34(5): 108718. doi: 10.1016/j.celrep.2021.108718
PMCID:
PMC7903328
AbstractArticlePDF–3.2M
18.
GPCR-dependent biasing of GIRK channel signaling dynamics by RGS6 in mouse sinoatrial nodal cells
Allison Anderson, Ikuo Masuho, Ezequiel Marron Fernandez de Velasco, Atsushi Nakano, Lutz Birnbaumer, Kirill A. Martemyanov, Kevin Wickman
Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14522–14531. Published online 2020 Jun 8. doi: 10.1073/pnas.2001270117
PMCID:
PMC7322085
AbstractArticlePDF–1.6M
19.
Nucleome Dynamics During Retinal Development
Jackie L. Norrie, Marybeth S. Lupo, Beisi Xu, Marc Valentine, Daniel Putnam, Issam Al Diri, Lyra Griffiths, Jiakun Zhang, Dianna Johnson, John Easton, Ying Shao, Victoria Honnell, Sharon Frase, Shondra Miller, Valerie Stewart, Xin Zhou, Xiang Chen, Michael A. Dyer
Neuron. Author manuscript; available in PMC 2020 Nov 6.
Published in final edited form as: Neuron. 2019 Nov 6; 104(3): 512–528.e11. Published online 2019 Sep 4. doi: 10.1016/j.neuron.2019.08.002
PMCID:
PMC6842117
AbstractArticlePDF–4.3M
20.
Bacterial MgrB peptide activates chemoreceptor Fpr3 in mouse accessory olfactory system and drives avoidance behaviour
Bernd Bufe, Yannick Teuchert, Andreas Schmid, Martina Pyrski, Anabel Pérez-Gómez, Janina Eisenbeis, Thomas Timm, Tomohiro Ishii, Günter Lochnit, Markus Bischoff, Peter Mombaerts, Trese Leinders-Zufall, Frank Zufall
Nat Commun. 2019; 10: 4889. Published online 2019 Oct 25. doi: 10.1038/s41467-019-12842-x
PMCID:
PMC6814738
AbstractArticlePDF–4.3M

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