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Items: 1 to 20 of 44

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome
Brianna K. Unda, Leon Chalil, Sehyoun Yoon, Savannah Kilpatrick, Courtney Irwin, Sansi Xing, Nadeem Murtaza, Anran Cheng, Chad Brown, Alexandria Afonso, Elizabeth McCready, Gabriel M. Ronen, Jennifer Howe, Aurélie Caye-Eude, Alain Verloes, Brad W. Doble, Laurence Faivre, Antonio Vitobello, Stephen W. Scherer, Yu Lu, Peter Penzes, Karun K. Singh
Mol Psychiatry. 2023; 28(4): 1747–1769. Published online 2023 Jan 6. doi: 10.1038/s41380-022-01937-5
PMCID:
PMC10208958
AbstractArticlePDF–7.0M
3.
ELMO1 Deficiency Reduces Neutrophil Chemotaxis in Murine Peritonitis
Shuxiang Yu, Xiaoke Geng, Huibing Liu, Yunyun Zhang, Xiumei Cao, Baojie Li, Jianshe Yan
Int J Mol Sci. 2023 May; 24(9): 8103. Published online 2023 Apr 30. doi: 10.3390/ijms24098103
PMCID:
PMC10179205
AbstractArticlePDF–2.3M
4.
The crosstalk between microbial sensors ELMO1 and NOD2 shape intestinal immune responses
Aditi Sharma, Sajan Chandrangadhan Achi, Stella-Rita Ibeawuchi, Mahitha Shree Anandachar, Hobie Gementera, Uddeep Chaudhury, Fatima Usmani, Kevin Vega, Ibrahim M Sayed, Soumita Das
Virulence. 2023; 14(1): 2171690. Published online 2023 Feb 19. doi: 10.1080/21505594.2023.2171690
PMCID:
PMC9980453
AbstractArticlePDF–2.4M
5.
Biasing the conformation of ELMO2 reveals that myoblast fusion can be exploited to improve muscle regeneration
Viviane Tran, Sarah Nahlé, Amélie Robert, Inès Desanlis, Ryan Killoran, Sophie Ehresmann, Marie-Pier Thibault, David Barford, Kodi S. Ravichandran, Martin Sauvageau, Matthew J. Smith, Marie Kmita, Jean-François Côté
Nat Commun. 2022; 13: 7077. Published online 2022 Nov 18. doi: 10.1038/s41467-022-34806-4
PMCID:
PMC9674853
AbstractArticlePDF–3.6M
6.
The interaction of enteric bacterial effectors with the host engulfment pathway control innate immune responses
Ibrahim M Sayed, Stella-Rita Ibeawuchi, Dominique Lie, Mahitha Shree Anandachar, Rama Pranadinata, Manuela Raffatellu, Soumita Das
Gut Microbes. 2021; 13(1): 1991776. Published online 2021 Nov 1. doi: 10.1080/19490976.2021.1991776
PMCID:
PMC8565811
AbstractArticlePDF–2.6M
7.
ELMO1 signaling is a promoter of osteoclast function and bone loss
Sanja Arandjelovic, Justin S. A. Perry, Ming Zhou, Adam Ceroi, Igor Smirnov, Scott F. Walk, Laura S. Shankman, Isabelle Cambré, Suna Onengut-Gumuscu, Dirk Elewaut, Thomas P. Conrads, Kodi S. Ravichandran
Nat Commun. 2021; 12: 4974. Published online 2021 Aug 17. doi: 10.1038/s41467-021-25239-6
PMCID:
PMC8371122
AbstractArticlePDF–3.1M
8.
ELMO1 Regulates RANKL-Stimulated Differentiation and Bone Resorption of Osteoclasts
Xinyue Liang, Yafei Hou, Lijuan Han, Shuxiang Yu, Yunyun Zhang, Xiumei Cao, Jianshe Yan
Front Cell Dev Biol. 2021; 9: 702916. Published online 2021 Jul 26. doi: 10.3389/fcell.2021.702916
PMCID:
PMC8350380
AbstractArticlePDF–2.3M
9.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
10.
Cyanocobalamin prevents cardiomyopathy in type 1 diabetes by modulating oxidative stress and DNMT-SOCS1/3-IGF-1 signaling
Masao Kakoki, Purushotham V. Ramanathan, John R. Hagaman, Ruriko Grant, Jennifer C. Wilder, Joan M. Taylor, J. Charles Jennette, Oliver Smithies, Nobuyo Maeda-Smithies
Commun Biol. 2021; 4: 775. Published online 2021 Jun 23. doi: 10.1038/s42003-021-02291-y
PMCID:
PMC8222371
AbstractArticlePDF–2.7M
11.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
12.
Host engulfment pathway controls inflammation in Inflammatory Bowel Disease
Ibrahim M Sayed, Katherine Suarez, Eileen Lim, Sujay Singh, Matheus Pereira, Stella-Rita Ibeawuchi, Gajanan Katkar, Ying Dunkel, Yash Mittal, Ranajoy Chattopadhyay, Monica Guma, Brigid S. Boland, Parambir S. Dulai, William J. Sandborn, Pradipta Ghosh, Soumita Das
FEBS J. Author manuscript; available in PMC 2020 Dec 9.
Published in final edited form as: FEBS J. 2020 Sep; 287(18): 3967–3988. Published online 2020 Feb 20. doi: 10.1111/febs.15236
PMCID:
PMC7390677
AbstractArticlePDF–2.7M
13.
Phosphatidylserine on viable sperm and phagocytic machinery in oocytes regulate mammalian fertilization
Claudia M. Rival, Wenhao Xu, Laura S. Shankman, Sho Morioka, Sanja Arandjelovic, Chang Sup Lee, Karen M. Wheeler, Ryan P. Smith, Lisa B. Haney, Brant E. Isakson, Scott Purcell, Jeffrey J. Lysiak, Kodi S. Ravichandran
Nat Commun. 2019; 10: 4456. Published online 2019 Oct 1. doi: 10.1038/s41467-019-12406-z
PMCID:
PMC6773685
AbstractArticlePDF–3.7M
14.
Engulfment and cell motility protein 1 potentiates diabetic cardiomyopathy via Rac-dependent and Rac-independent ROS production
Masao Kakoki, Edward M. Bahnson, John R. Hagaman, Robin M. Siletzky, Ruriko Grant, Yukako Kayashima, Feng Li, Esther Y. Lee, Michelle T. Sun, Joan M. Taylor, Jessica C. Rice, Michael F. Almeida, Ben A. Bahr, J. Charles Jennette, Oliver Smithies, Nobuyo Maeda-Smithies
JCI Insight. 2019 Jun 20; 4(12): e127660. Published online 2019 Jun 20. doi: 10.1172/jci.insight.127660
PMCID:
PMC6629098
AbstractArticlePDF–5.4M
15.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
16.
A non-canonical role for the engulfment gene ELMO1 in neutrophils that promotes inflammatory arthritis
Sanja Arandjelovic, Justin S.A. Perry, Christopher D. Lucas, Kristen K. Penberthy, Tae-Hyoun Kim, Ming Zhou, Dorian A Rosen, Tzu-Ying Chuang, Alexandra M. Bettina, Laura S. Shankman, Amanda H. Cohen, Alban Gaultier, Thomas P. Conrads, Minsoo Kim, Michael R. Elliott, Kodi S. Ravichandran
Nat Immunol. Author manuscript; available in PMC 2019 Jul 14.
Published in final edited form as: Nat Immunol. 2019 Feb; 20(2): 141–151. Published online 2019 Jan 14. doi: 10.1038/s41590-018-0293-x
PMCID:
PMC6402828
AbstractArticlePDF–2.9M
17.
ELMO1 deficiency enhances platelet function
Akruti Patel, John Kostyak, Carol Dangelmaier, Rachit Badolia, Dheeraj Bhavanasi, Joseph E. Aslan, Salim Merali, Soochong Kim, Johannes A. Eble, Lawrence Goldfinger, Satya Kunapuli
Blood Adv. 2019 Feb 26; 3(4): 575–587. Published online 2019 Feb 20. doi: 10.1182/bloodadvances.2018016444
PMCID:
PMC6391667
AbstractArticlePDF–1.9M
18.
ATG5 is required for B cell polarization and presentation of particulate antigens
Florent Arbogast, Johan Arnold, Philippe Hammann, Lauriane Kuhn, Johana Chicher, Diane Murera, Justine Weishaar, Sylviane Muller, Jean-Daniel Fauny, Frédéric Gros
Autophagy. 2019; 15(2): 280–294. Published online 2018 Sep 22. doi: 10.1080/15548627.2018.1516327
PMCID:
PMC6333460
AbstractArticlePDF–2.7M
19.
RNA binding proteins co-localize with small tau inclusions in tauopathy
Brandon F. Maziuk, Daniel J. Apicco, Anna Lourdes Cruz, Lulu Jiang, Peter E. A. Ash, Edroaldo Lummertz da Rocha, Cheng Zhang, Wai Haung Yu, John Leszyk, Jose F. Abisambra, Hu Li, Benjamin Wolozin
Acta Neuropathol Commun. 2018; 6: 71. Published online 2018 Aug 1. doi: 10.1186/s40478-018-0574-5
PMCID:
PMC6069705
AbstractArticlePDF–5.5M
20.
Neuronal adaptor FE65 stimulates Rac1-mediated neurite outgrowth by recruiting and activating ELMO1
Wen Li, Ka Ming Vincent Tam, Wai Wa Ray Chan, Alex Chun Koon, Jacky Chi Ki Ngo, Ho Yin Edwin Chan, Kwok-Fai Lau
J Biol Chem. 2018 May 18; 293(20): 7674–7688. Published online 2018 Apr 3. doi: 10.1074/jbc.RA117.000505
PMCID:
PMC5961050
AbstractArticlePDF–3.5M

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