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Select item 103078521.

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility

Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao

Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5

PMCID:: PMC10307852

Abstract Article PDF–8.8M

Select item 58627712.

A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies

David K. Breslow, Sascha Hoogendoorn, Adam R. Kopp, David W. Morgens, Brandon K. Vu, Margaret C. Kennedy, Kyuho Han, Amy Li, Gaelen T. Hess, Michael C. Bassik, James K. Chen, Maxence V. Nachury

Nat Genet. Author manuscript; available in PMC 2018 Aug 19.

Published in final edited form as: Nat Genet. 2018 Mar; 50(3): 460–471. Published online 2018 Feb 19. doi: 10.1038/s41588-018-0054-7

PMCID:: PMC5862771

Abstract Article PDF–2.5M

Select item 56533983.

A murine Ig light chain transgene reveals IGKV3 gene contributions to anti-collagen types IV and II specificities

Amy G. Clark, Inge M. Worni-Schudel, Francesca M. Korte, Mary H. Foster

Mol Immunol. Author manuscript; available in PMC 2018 Nov 1.

Published in final edited form as: Mol Immunol. 2017 Nov; 91: 49–56. Published online 2017 Sep 5. doi: 10.1016/j.molimm.2017.08.015

PMCID:: PMC5653398

Abstract Article PDF–521K

Select item 53812264.

Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function

Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang

Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626

PMCID:: PMC5381226

Abstract Article PDF–1.4M

Select item 52236055.

B cell antigen extraction is regulated by physical properties of antigen-presenting cells

Katelyn M. Spillane, Pavel Tolar

J Cell Biol. 2017 Jan 2; 216(1): 217–230. doi: 10.1083/jcb.201607064

PMCID:: PMC5223605

Abstract Article PDF–2.1M

Select item 47734456.

Local T/B cooperation in inflamed tissues is supported by T follicular helper-like cells

Dana Vu Van, Katja C. Beier, Lea-Jean Pietzke, Maysun S. Al Baz, Randi K. Feist, Stephanie Gurka, Eckard Hamelmann, Richard A. Kroczek, Andreas Hutloff

Nat Commun. 2016; 7: 10875. Published online 2016 Feb 26. doi: 10.1038/ncomms10875

PMCID:: PMC4773445

Abstract Article PDF–2.0M

Select item 47372337.

The expression of mouse CLEC‐2 on leucocyte subsets varies according to their anatomical location and inflammatory state

Kate L. Lowe, Leyre Navarro‐Núñez, Cécile Bénézech, Saba Nayar, Bethany L. Kingston, Bernhard Nieswandt, Francesca Barone, Steve P. Watson, Christopher D. Buckley, Guillaume E. Desanti

Eur J Immunol. 2015 Sep; 45(9): 2484–2493. Published online 2015 Aug 12. doi: 10.1002/eji.201445314

PMCID:: PMC4737233

Abstract Article PDF–823K

Select item 46185108.

Inhibition of non-homologous end joining increases the efficiency of CRISPR/Cas9-mediated precise [TM: inserted] genome editing

Takeshi Maruyama, Stephanie K. Dougan, Matthias Truttmann, Angelina M. Bilate, Jessica R. Ingram, Hidde L. Ploegh

Nat Biotechnol. Author manuscript; available in PMC 2015 Nov 1.

Published in final edited form as: Nat Biotechnol. 2015 May; 33(5): 538–542. Published online 2015 Mar 23. doi: 10.1038/nbt.3190

Correction in:: Nat Biotechnol. 2016 Feb; 34(2): 210.

PMCID:: PMC4618510

Abstract Article PDF–585K

Select item 45768589.

Prosaposin facilitates sortilin-independent lysosomal trafficking of progranulin

Xiaolai Zhou, Lirong Sun, Francisco Bastos de Oliveira, Xiaoyang Qi, William J. Brown, Marcus B. Smolka, Ying Sun, Fenghua Hu

J Cell Biol. 2015 Sep 14; 210(6): 991–1002. doi: 10.1083/jcb.201502029

PMCID:: PMC4576858

Abstract Article PDF–3.0M

Select item 432204910.

ICOS maintains the T follicular helper cell phenotype by down-regulating Krüppel-like factor 2

Jan P. Weber, Franziska Fuhrmann, Randi K. Feist, Annette Lahmann, Maysun S. Al Baz, Lea-Jean Gentz, Dana Vu Van, Hans W. Mages, Claudia Haftmann, René Riedel, Joachim R. Grün, Wolfgang Schuh, Richard A. Kroczek, Andreas Radbruch, Mir-Farzin Mashreghi, Andreas Hutloff

J Exp Med. 2015 Feb 9; 212(2): 217–233. doi: 10.1084/jem.20141432

PMCID:: PMC4322049

Abstract Article PDF–4.2M

Select item 428395511.

The Proximal J Kappa Germline-Transcript Promoter Facilitates Receptor Editing through Control of Ordered Recombination

Christian Vettermann, Greg A. Timblin, Vivian Lim, Ernest C. Lai, Mark S. Schlissel

PLoS One. 2015; 10(1): e0113824. Published online 2015 Jan 5. doi: 10.1371/journal.pone.0113824

PMCID:: PMC4283955

Abstract Article PDF–606K

Select item 407349412.

The Central Role of EED in the Orchestration of Polycomb Group Complexes

Qi Cao, Xiaoju Wang, Meng Zhao, Rendong Yang, Rohit Malik, Yuanyuan Qiao, Anton Poliakov, Anastasia K. Yocum, Yong Li, Wei Chen, Xuhong Cao, Xia Jiang, Arun Dahiya, Clair Harris, Felix Y. Feng, Sundeep Kalantry, Zhaohui S. Qin, Saravana M. Dhanasekaran, Arul M. Chinnaiyan

Nat Commun. Author manuscript; available in PMC 2014 Jul 24.

Published in final edited form as: Nat Commun. 2014; 5: 3127. doi: 10.1038/ncomms4127

PMCID:: PMC4073494

Abstract Article PDF–2.1M

Select item 405276313.

MZB1 is a GRP94 cochaperone that enables proper immunoglobulin heavy chain biosynthesis upon ER stress

Marc Rosenbaum, Virginia Andreani, Tanya Kapoor, Simone Herp, Henrik Flach, Marlena Duchniewicz, Rudolf Grosschedl

Genes Dev. 2014 Jun 1; 28(11): 1165–1178. doi: 10.1101/gad.240762.114

PMCID:: PMC4052763

Abstract Article PDF–1.8M

Select item 379272014.

A Role for Nuclear Factor Kappa B/Rel Transcription Factors in the Regulation of the Recombinase Activator Genes

Laurent Verkoczy, Djemel Aїt-Azzouzene, Patrick Skog, Annica Märtensson, Julie Lang, Bao Duong, David Nemazee

Immunity. Author manuscript; available in PMC 2013 Oct 8.

Published in final edited form as: Immunity. 2005 Apr; 22(4): 519–531. doi: 10.1016/j.immuni.2005.03.006

PMCID:: PMC3792720

Abstract Article PDF–5.5M

Select item 377322815.

Immune tolerance negatively regulates B cells in knock-in mice expressing broadly neutralizing HIV antibody 4E10

Colleen Doyle-Cooper, Krystalyn E. Hudson, Anthony B. Cooper, Takayuki Ota, Patrick Skog, Phillip E. Dawson, Michael B. Zwick, William R. Schief, Dennis R. Burton, David Nemazee

J Immunol. Author manuscript; available in PMC 2014 Sep 15.

Published in final edited form as: J Immunol. 2013 Sep 15; 191(6): 3186–3191. Published online 2013 Aug 12. doi: 10.4049/jimmunol.1301285

PMCID:: PMC3773228

Abstract Article PDF–1.1M

Select item 356386316.

Vκ gene repertoire and locus contraction are specified by critical DNase I hypersensitive sites within the Vκ-Jκ intervening region

Yougui Xiang, Sung-Kyun Park, William T. Garrard

J Immunol. Author manuscript; available in PMC 2014 Feb 15.

Published in final edited form as: J Immunol. 2013 Feb 15; 190(4): 1819–1826. Published online 2013 Jan 7. doi: 10.4049/jimmunol.1203127

PMCID:: PMC3563863

Abstract Article PDF–1.4M

Select item 354971917.

Global analysis of B cell selection using an immunoglobulin light chain–mediated model of autoreactivity

Sarah F. Andrews, Qingzhao Zhang, Samuel Lim, Lie Li, Jane-Hwei Lee, Nai-Ying Zheng, Min Huang, William M. Taylor, A. Darise Farris, Dongyao Ni, Wenzhao Meng, Eline T. Luning Prak, Patrick C. Wilson

J Exp Med. 2013 Jan 14; 210(1): 125–142. doi: 10.1084/jem.20120525

PMCID:: PMC3549719

Abstract Article PDF–3.7M

Select item 347860618.

Impact of lactobacilli on orally acquired listeriosis

Cristel Archambaud, Marie-Anne Nahori, Guillaume Soubigou, Christophe Bécavin, Laure Laval, Pierre Lechat, Tamara Smokvina, Philippe Langella, Marc Lecuit, Pascale Cossart

Proc Natl Acad Sci U S A. 2012 Oct 9; 109(41): 16684–16689. Published online 2012 Sep 24. doi: 10.1073/pnas.1212809109