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Select item 115370691.

Structural Insight into Binding of the ZZ Domain of HERC2 to Histone H3 and SUMO1

Jiuyang Liu, Zhaoyu Xue, Yi Zhang, Kendra R. Vann, Xiaobing Shi, Tatiana G. Kutateladze

Structure. Author manuscript; available in PMC 2024 Nov 5.

Published in final edited form as: Structure. 2020 Nov 3; 28(11): 1225–1230.e3. Published online 2020 Jul 28. doi: 10.1016/j.str.2020.07.003

PMCID:: PMC11537069

Abstract Article PDF–863K

Select item 111094832.

K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors

Anita Waltho, Oliver Popp, Christopher Lenz, Lukas Pluska, Mahil Lambert, Volker Dötsch, Philipp Mertins, Thomas Sommer

Life Sci Alliance. 2024 Aug; 7(8): e202402740. Published online 2024 May 21. doi: 10.26508/lsa.202402740

PMCID:: PMC11109483

Abstract Article PDF–2.9M

Select item 109457073.

Comparative interactome analysis of α-arrestin families in human and Drosophila

Kyung-Tae Lee, Inez KA Pranoto, Soon-Young Kim, Hee-Joo Choi, Ngoc Bao To, Hansong Chae, Jeong-Yeon Lee, Jung-Eun Kim, Young V Kwon, Jin-Wu Nam

eLife. 2024; 12: RP88328. Published online 2024 Jan 25. doi: 10.7554/eLife.88328

PMCID:: PMC10945707

Abstract Article PDF–2.8M

Select item 105019954.

Mechanism of orphan subunit recognition during assembly quality control

Yuichi Yagita, Eszter Zavodszky, Sew-Yeu Peak-Chew, Ramanujan S. Hegde

Cell. 2023 Aug 3; 186(16): 3443–3459.e24. doi: 10.1016/j.cell.2023.06.016

PMCID:: PMC10501995

Abstract Article

Select item 104068365.

CAMK2D serves as a molecular scaffold for RNF8-MAD2 complex to induce mitotic checkpoint in glioma

You Heng Chuah, Emmy Xue Yun Tay, Oleg V. Grinchuk, Jeehyun Yoon, Jia Feng, Srinivasaraghavan Kannan, Matius Robert, Rekha Jakhar, Yajing Liang, Bernice Woon Li Lee, Loo Chien Wang, Yan Ting Lim, Tianyun Zhao, Radoslaw M. Sobota, Guang Lu, Boon Chuan Low, Karen Carmelina Crasta, Chandra Shekhar Verma, Zhewang Lin, Derrick Sek Tong Ong

Cell Death Differ. 2023 Aug; 30(8): 1973–1987. Published online 2023 Jul 19. doi: 10.1038/s41418-023-01192-3

PMCID:: PMC10406836

Abstract Article PDF–5.9M

Select item 103296826.

UBE2S interacting with TRIM21 mediates the K11-linked ubiquitination of LPP to promote the lymphatic metastasis of bladder cancer

Kanghua Xiao, Shengmeng Peng, Junlin Lu, Ting Zhou, Xuwei Hong, Siting Chen, Guangyao Liu, Hong Li, Jian Huang, Xu Chen, Tianxin Lin

Cell Death Dis. 2023 Jul; 14(7): 408. Published online 2023 Jul 8. doi: 10.1038/s41419-023-05938-2

PMCID:: PMC10329682

Abstract Article PDF–20M

Select item 102401897.

EHD1 promotes CP110 ubiquitination by centriolar satellite delivery of HERC2 to the mother centriole

Shuwei Xie, Naava Naslavsky, Steve Caplan

EMBO Rep. 2023 Jun; 24(6): e56317. Published online 2023 Apr 19. doi: 10.15252/embr.202256317

PMCID:: PMC10240189

Abstract Article PDF–4.0M

Select item 102374228.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 101968049.

Oxygen modulates iron homeostasis by switching iron sensing of NCOA4

Sota Kuno, Kazuhiro Iwai

J Biol Chem. 2023 May; 299(5): 104701. Published online 2023 Apr 13. doi: 10.1016/j.jbc.2023.104701

PMCID:: PMC10196804

Abstract Article PDF–2.7M

Select item 995018310.

CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment

Daphne J. Smits, Jordy Dekker, Rachel Schot, Brahim Tabarki, Amal Alhashem, Jeroen A. A. Demmers, Dick H. W. Dekkers, Antonio Romito, Peter J. van der Spek, Tjakko J. van Ham, Aida M. Bertoli-Avella, Grazia M. S. Mancini

Hum Genet. 2023; 142(3): 379–397. Published online 2022 Dec 20. doi: 10.1007/s00439-022-02511-3

PMCID:: PMC9950183

Abstract Article PDF–2.4M

Select item 989072211.

HERC2 promotes inflammation-driven cancer stemness and immune evasion in hepatocellular carcinoma by activating STAT3 pathway

Yunzhi Liu, Qishan Xu, Fan Deng, Zhuojun Zheng, Jialiang Luo, Ping Wang, Jia Zhou, Xiao Lu, Liyun Zhang, Zhengliang Chen, Qifan Zhang, Qingyun Chen, Daming Zuo

J Exp Clin Cancer Res. 2023; 42: 38. Published online 2023 Feb 1. doi: 10.1186/s13046-023-02609-0

Correction in:: J Exp Clin Cancer Res. 2024; 43: 300.

PMCID:: PMC9890722

Abstract Article PDF–11M

Select item 984348812.

Regulator of G protein signaling 12 drives inflammatory arthritis by activating synovial fibroblasts through MYCBP2/KIF2A signaling

Gongsheng Yuan, Shu-ting Yang, Shuying Yang

Mol Ther Nucleic Acids. 2023 Mar 14; 31: 197–210. Published online 2022 Dec 27. doi: 10.1016/j.omtn.2022.12.017

PMCID:: PMC9843488

Abstract Article PDF–4.7M

Select item 980457913.

Common genetic variants associated with melanoma risk or naevus count in patients with wildtype MC1R melanoma

Neus Calbet‐Llopart, Marc Combalia, Anil Kiroglu, Miriam Potrony, Gemma Tell‐Martí, Andrea Combalia, Albert Brugues, Sebastian Podlipnik, Cristina Carrera, Susana Puig, Josep Malvehy, Joan Anton Puig‐Butillé

Br J Dermatol. 2022 Nov; 187(5): 753–764. Published online 2022 Aug 11. doi: 10.1111/bjd.21707

PMCID:: PMC9804579

Abstract Article PDF–977K

Select item 977255814.

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation

Jingsheng Yuan, Tao Lv, Jian Yang, Zhenru Wu, Lvnan Yan, Jiayin Yang, Yujun Shi, Li Jiang

Cell Mol Gastroenterol Hepatol. 2023; 15(2): 307–325. Published online 2022 Oct 14. doi: 10.1016/j.jcmgh.2022.10.005

PMCID:: PMC9772558

Abstract Article PDF–8.2M

Select item 976969815.

A whole genome CRISPR screen identifies AHR loss as a mechanism of resistance to a PARP7 inhibitor

Huadong Chen, Morgan E. Diolaiti, Patrick C. O’Leary, Ajda Rojc, Nevan J. Krogan, Minkyu Kim, Alan Ashworth

Mol Cancer Ther. Author manuscript; available in PMC 2023 Jan 5.

Published in final edited form as: Mol Cancer Ther. 2022 Jul 5; 21(7): 1076–1089. doi: 10.1158/1535-7163.MCT-21-0841

PMCID:: PMC9769698

Abstract Article PDF–2.7M

Select item 956846316.

HERC2 deficiency activates C-RAF/MKK3/p38 signalling pathway altering the cellular response to oxidative stress

Joan Sala-Gaston, Leonardo Pedrazza, Juanma Ramirez, Arturo Martinez-Martinez, Lettie E. Rawlins, Emma L. Baple, Andrew H. Crosby, Ugo Mayor, Francesc Ventura, Jose Luis Rosa

Cell Mol Life Sci. 2022; 79(11): 548. Published online 2022 Oct 14. doi: 10.1007/s00018-022-04586-7

PMCID:: PMC9568463

Abstract Article PDF–7.5M

Select item 954034517.

The in vivo Interaction Landscape of Histones H3.1 and H3.3

Robert Siddaway, Scott Milos, Étienne Coyaud, Hwa Young Yun, Shahir M. Morcos, Sanja Pajovic, Eric I. Campos, Brian Raught, Cynthia Hawkins

Mol Cell Proteomics. 2022 Oct; 21(10): 100411. Published online 2022 Sep 9. doi: 10.1016/j.mcpro.2022.100411

PMCID:: PMC9540345

Abstract Article PDF–3.9M

Select item 952364518.

SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis

Jun-yi Zhu, Guanglei Wang, Xiaohu Huang, Hangnoh Lee, Jin-Gu Lee, Penghua Yang, Joyce van de Leemput, Weiliang Huang, Maureen A. Kane, Peixin Yang, Zhe Han

Commun Biol. 2022; 5: 1039. Published online 2022 Sep 30. doi: 10.1038/s42003-022-03986-6