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Select item 108478771.

Collaborative effect of Csnk1a1 haploinsufficiency and mutant p53 in Myc induction can promote leukemic transformation

Stijn N. R. Fuchs, Ursula S. A. Stalmann, Inge A. M. Snoeren, Eric Bindels, Stephani Schmitz, Bella Banjanin, Remco M. Hoogenboezem, Stanley van Herk, Mohamed Saad, Wencke Walter, Torsten Haferlach, Lancelot Seillier, Julio Saez-Rodriguez, Aurélien J. F. Dugourd, Kjong-Van Lehmann, Yinon Ben-Neriah, Hélène F. E. Gleitz, Rebekka K. Schneider

Blood Adv. 2024 Feb 13; 8(3): 766–779. Published online 2023 Dec 28. doi: 10.1182/bloodadvances.2022008926

PMCID:: PMC10847877

Abstract Article PDF–3.8M

Select item 101652552.

Casein kinase 1α is required to maintain murine hypothalamic pro-opiomelanocortin expression

Chenyang Lu, Jinglin Zhang, Bingjie Wang, Qiao Gao, Kezhe Ma, Shaona Pei, Juxue Li, Sheng Cui

iScience. 2023 May 19; 26(5): 106670. Published online 2023 Apr 14. doi: 10.1016/j.isci.2023.106670

PMCID:: PMC10165255

Abstract Article PDF–8.2M

Select item 101388823.

Casein Kinase 1α as a Novel Factor Affects Thyrotropin Synthesis via PKC/ERK/CREB Signaling

Bingjie Wang, Jinglin Zhang, Di Zhang, Chenyang Lu, Hui Liu, Qiao Gao, Tongjuan Niu, Mengqing Yin, Sheng Cui

Int J Mol Sci. 2023 Apr; 24(8): 7034. Published online 2023 Apr 11. doi: 10.3390/ijms24087034

PMCID:: PMC10138882

Abstract Article PDF–20M

Select item 100748484.

Glutaredoxin 1 protects lens epithelial cells from epithelial-mesenchymal transition by preventing casein kinase 1α S-glutathionylation during posterior capsular opacification

Chenshuang Li, Xi Chen, Siqi Zhang, Chen Liang, Xiaopan Ma, Ruixue Zhang, Hong Yan

Redox Biol. 2023 Jun; 62: 102676. Published online 2023 Mar 24. doi: 10.1016/j.redox.2023.102676

PMCID:: PMC10074848

Abstract Article PDF–16M

Select item 92897095.

TRIM27 cooperates with STK38L to inhibit ULK1‐mediated autophagy and promote tumorigenesis

Yi Yang, Yifu Zhu, Shuai Zhou, Peipei Tang, Ran Xu, Yuwei Zhang, Dongping Wei, Jian Wen, Rick F Thorne, Xu Dong Zhang, Jun‐Lin Guan, Lianxin Liu, Mian Wu, Song Chen

EMBO J. 2022 Jul; 41(14): e109777. Published online 2022 Jun 7. doi: 10.15252/embj.2021109777

PMCID:: PMC9289709

Abstract Article PDF–2.3M

Select item 85756616.

MDMX acts as a pervasive preleukemic-to-acute myeloid leukemia transition mechanism

Koki Ueda, Rajni Kumari, Emily Schwenger, Justin C. Wheat, Oliver Bohorquez, Swathi-Rao Narayanagari, Samuel J. Taylor, Luis A. Carvajal, Kith Pradhan, Boris Bartholdy, Tihomira I. Todorova, Hiroki Goto, Daqian Sun, Jiahao Chen, Jidong Shan, Yinghui Song, Cristina Montagna, Shunbin Xiong, Guillermina Lozano, Andrea Pellagatti, Jacqueline Boultwood, Amit Verma, Ulrich Steidl

Cancer Cell. Author manuscript; available in PMC 2022 Apr 12.

Published in final edited form as: Cancer Cell. 2021 Apr 12; 39(4): 529–547.e7. Published online 2021 Mar 4. doi: 10.1016/j.ccell.2021.02.006

PMCID:: PMC8575661

Abstract Article PDF–3.7M

Select item 84949227.

NLRP3 phosphorylation in its LRR domain critically regulates inflammasome assembly

Tingting Niu, Charlotte De Rosny, Séverine Chautard, Amaury Rey, Danish Patoli, Marine Groslambert, Camille Cosson, Brice Lagrange, Zhirong Zhang, Orane Visvikis, Sabine Hacot, Maggy Hologne, Olivier Walker, Jeimin Wong, Ping Wang, Roméo Ricci, Thomas Henry, Laurent Boyer, Virginie Petrilli, Bénédicte F. Py

Nat Commun. 2021; 12: 5862. Published online 2021 Oct 6. doi: 10.1038/s41467-021-26142-w

PMCID:: PMC8494922

Abstract Article PDF–3.7M

Select item 83356958.

Csnk1a1 inhibition modulates the inflammatory secretome and enhances response to radiotherapy in glioma

Guanzheng Liu, Huan Li, Wanhong Zhang, Jiefeng Yu, Xu Zhang, Runqiu Wu, Mingshan Niu, Xuejiao Liu, Rutong Yu

J Cell Mol Med. 2021 Aug; 25(15): 7395–7406. Published online 2021 Jul 3. doi: 10.1111/jcmm.16767

Correction in:: J Cell Mol Med. 2022 May; 26(9): 2754–2755.

PMCID:: PMC8335695

Abstract Article PDF–2.2M

Select item 81915149.

Cx43 phosphorylation sites regulate pancreatic cancer metastasis

Joell L. Solan, Sunil R. Hingorani, Paul D. Lampe

Oncogene. Author manuscript; available in PMC 2021 Aug 18.

Published in final edited form as: Oncogene. 2021 Mar; 40(10): 1909–1920. Published online 2021 Feb 18. doi: 10.1038/s41388-021-01668-x

PMCID:: PMC8191514

Abstract Article PDF–2.4M

Select item 793877010.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 741599111.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 736128512.

MDMX inhibits casein kinase 1α activity and stimulates Wnt signaling

Qingling Huang, Lihong Chen, Ernst Schonbrunn, Jiandong Chen

EMBO J. 2020 Jul 15; 39(14): e104410. Published online 2020 Jun 8. doi: 10.15252/embj.2020104410

PMCID:: PMC7361285

Abstract Article PDF–3.7M

Select item 729503313.

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant

Meagan A. Quinlan, Matthew J. Robson, Ran Ye, Kristie L. Rose, Kevin L. Schey, Randy D. Blakely

Front Mol Neurosci. 2020; 13: 89. Published online 2020 Jun 8. doi: 10.3389/fnmol.2020.00089

PMCID:: PMC7295033

Abstract Article PDF–2.7M

Select item 714221914.

A CK1α Activator Penetrates the Brain and Shows Efficacy Against Drug-resistant Metastatic Medulloblastoma

Jezabel Rodriguez-Blanco, Bin Li, Jun Long, Chen Shen, Fan Yang, Darren Orton, Sara Collins, Noriyuki Kasahara, Nagi G. Ayad, Heather J. McCrea, Martine F. Roussel, William A. Weiss, Anthony J. Capobianco, David J. Robbins

Clin Cancer Res. Author manuscript; available in PMC 2020 Apr 9.

Published in final edited form as: Clin Cancer Res. 2019 Feb 15; 25(4): 1379–1388. Published online 2018 Nov 28. doi: 10.1158/1078-0432.CCR-18-1319

PMCID:: PMC7142219

Abstract Article PDF–1.4M

Select item 711671215.

The gut microbiome switches mutant p53 from tumour-suppressive to oncogenic

Eliran Kadosh, Irit Snir-Alkalay, Avanthika Venkatachalam, Shahaf May, Audrey Lasry, Ela Elyada, Adar Zinger, Maya Shaham, Gitit Vaalani, Marco Mernberger, Thorsten Stiewe, Eli Pikarsky, Moshe Oren, Yinon Ben-Neriah

Nature. Author manuscript; available in PMC 2021 Feb 9.

Published in final edited form as: Nature. 2020 Oct 1; 586(7827): 133–138. Published online 2020 Jul 29. doi: 10.1038/s41586-020-2541-0

PMCID:: PMC7116712

Abstract Article PDF–7.2M

Select item 672690716.

FAM83D directs protein kinase CK1α to the mitotic spindle for proper spindle positioning

Luke J Fulcher, Zhengcheng He, Lin Mei, Thomas J Macartney, Nicola T Wood, Alan R Prescott, Arlene J Whigham, Joby Varghese, Robert Gourlay, Graeme Ball, Rosemary Clarke, David G Campbell, Christopher A Maxwell, Gopal P Sapkota

EMBO Rep. 2019 Sep; 20(9): e47495. Published online 2019 Jul 24. doi: 10.15252/embr.201847495

PMCID:: PMC6726907

Abstract Article PDF–2.8M

Select item 672542217.

Physiological Role for Casein Kinase 1 in Glutamatergic Synaptic Transmission

Karima Chergui, Per Svenningsson, Paul Greengard

J Neurosci. 2005 Jul 13; 25(28): 6601–6609. doi: 10.1523/JNEUROSCI.1082-05.2005

PMCID:: PMC6725422

Abstract Article PDF–679K

Select item 669277018.

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics

Joel D. Federspiel, Todd M. Greco, Krystal K. Lum, Ileana M. Cristea

Mol Cell Proteomics. 2019 Aug 9; 18(8 Suppl 1): S92–S113. Published online 2019 Apr 30. doi: 10.1074/mcp.RA118.001253

PMCID:: PMC6692770

Abstract Article PDF–7.7M

Select item 638114319.

An FBXW7-ZEB2 axis links EMT and tumour microenvironment to promote colorectal cancer stem cells and chemoresistance

Ningning Li, Roya Babaei-Jadidi, Federica Lorenzi, Bradley Spencer-Dene, Philip Clarke, Enric Domingo, Eugene Tulchinsky, Robert G. J. Vries, David Kerr, Yihang Pan, Yulong He, David O. Bates, Ian Tomlinson, Hans Clevers, Abdolrahman S. Nateri

Oncogenesis. 2019 Mar; 8(3): 13. Published online 2019 Feb 19. doi: 10.1038/s41389-019-0125-3

PMCID:: PMC6381143

Abstract Article PDF–10M

Select item 633346020.

ATG5 is required for B cell polarization and presentation of particulate antigens

Florent Arbogast, Johan Arnold, Philippe Hammann, Lauriane Kuhn, Johana Chicher, Diane Murera, Justine Weishaar, Sylviane Muller, Jean-Daniel Fauny, Frédéric Gros

Autophagy. 2019; 15(2): 280–294. Published online 2018 Sep 22. doi: 10.1080/15548627.2018.1516327

PMCID:: PMC6333460

Abstract Article PDF–2.7M

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