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Select item 110780151.

NLRP6 negatively regulates host defense against polymicrobial sepsis

Laxman Ghimire, Sagar Paudel, John Le, Liliang Jin, Shanshan Cai, Dinesh Bhattarai, Samithamby Jeyaseelan

Front Immunol. 2024; 15: 1248907. Published online 2024 Apr 23. doi: 10.3389/fimmu.2024.1248907

PMCID:: PMC11078015

Abstract Article PDF–4.5M

Select item 107493322.

NLRP6 controls pulmonary inflammation from cigarette smoke in a gut microbiota-dependent manner

Mégane Nascimento, Sarah Huot-Marchand, Manoussa Fanny, Marjolène Straube, Marc Le Bert, Florence Savigny, Lionel Apetoh, Jacques Van Snick, Fabrice Trovero, Mathias Chamaillard, Valérie F. J. Quesniaux, Bernhard Ryffel, Philippe Gosset, Aurélie Gombault, Nicolas Riteau, Harry Sokol, Isabelle Couillin

Front Immunol. 2023; 14: 1224383. Published online 2023 Dec 11. doi: 10.3389/fimmu.2023.1224383

PMCID:: PMC10749332

Abstract Article PDF–8.1M

Select item 101790703.

NPAS4 Exacerbates Pyroptosis via Transcriptionally Regulating NLRP6 in the Acute Phase of Intracerebral Hemorrhage in Mice

Dan Jian, Le Qin, Hui Gan, Shuyue Zheng, Han Xiao, Yuhao Duan, Mi Zhang, Ping Liang, Jing Zhao, Xuan Zhai

Int J Mol Sci. 2023 May; 24(9): 8320. Published online 2023 May 5. doi: 10.3390/ijms24098320

PMCID:: PMC10179070

Abstract Article PDF–2.8M

Select item 99957524.

NLRP6 deficiency expands a novel CD103⁺ B cell population that confers immune tolerance in NOD mice

James A. Pearson, Jian Peng, Juan Huang, Xiaoqing Yu, Ningwen Tai, Youjia Hu, Sha Sha, Richard A. Flavell, Hongyu Zhao, F. Susan Wong, Li Wen

Front Immunol. 2023; 14: 1147925. Published online 2023 Feb 23. doi: 10.3389/fimmu.2023.1147925

PMCID:: PMC9995752

Abstract Article PDF–4.6M

Select item 95872205.

NLRP6 is required for cancer-derived exosome-modified macrophage M2 polarization and promotes metastasis in small cell lung cancer

Xinrui Rao, Xiaoshu Zhou, Geng Wang, Xiaohua Jie, Biyuan Xing, Yingzhuo Xu, Yunshang Chen, Jun Li, Kuikui Zhu, Zilong Wu, Gang Wu, Chuangyan Wu, Rui Zhou

Cell Death Dis. 2022 Oct; 13(10): 891. Published online 2022 Oct 21. doi: 10.1038/s41419-022-05336-0

PMCID:: PMC9587220

Abstract Article PDF–6.7M

Select item 95584066.

The important role of NLRP6 inflammasome in Pasteurella multocida infection

Xingping Wu, Zheng Zeng, Hongliang Tian, Lianci Peng, Dongyi Xu, Yu Wang, Chao Ye, Yuanyi Peng, Rendong Fang

Vet Res. 2022; 53: 81. Published online 2022 Oct 12. doi: 10.1186/s13567-022-01095-0

PMCID:: PMC9558406

Abstract Article PDF–6.1M

Select item 87736067.

NLRP6 Inflammasome Modulates Disease Progression in a Chronic-Plus-Binge Mouse Model of Alcoholic Liver Disease

Rebecca Elena Mainz, Stefanie Albers, Madhuri Haque, Roland Sonntag, Nicole Simone Treichel, Thomas Clavel, Eicke Latz, Kai Markus Schneider, Christian Trautwein, Tobias Otto

Cells. 2022 Jan; 11(2): 182. Published online 2022 Jan 6. doi: 10.3390/cells11020182

PMCID:: PMC8773606

Abstract Article PDF–4.1M

Select item 86432778.

Phase Separation Drives RNA Virus-Induced Activation of the NLRP6 Inflammasome

Chen Shen, Runzhi Li, Roberto Negro, Jiewei Cheng, Setu Vora, Tian-Min Fu, Anmin Wang, Kaixin He, Liudmila Andreeva, Pu Gao, Zhigang Tian, Richard Flavell, Shu Zhu, Hao Wu

Cell. Author manuscript; available in PMC 2022 Nov 11.

Published in final edited form as: Cell. 2021 Nov 11; 184(23): 5759–5774.e20. Published online 2021 Oct 21. doi: 10.1016/j.cell.2021.09.032

PMCID:: PMC8643277

Abstract Article PDF–3.1M

Select item 80848699.

NLRP6 Modulates Neutrophil Homeostasis in Bacterial Pneumonia-Derived Sepsis

Shanshan Cai, Sagar Paudel, Liliang Jin, Laxman Ghimire, Christopher M. Taylor, Nobuko Wakamatsu, Dinesh Bhattarai, Samithamby Jeyaseelan

Mucosal Immunol. Author manuscript; available in PMC 2021 May 23.

Published in final edited form as: Mucosal Immunol. 2021 May; 14(3): 574–584. Published online 2020 Nov 23. doi: 10.1038/s41385-020-00357-4

PMCID:: PMC8084869

Abstract Article PDF–1.9M

Select item 806910010.

The Critical Role of NLRP6 Inflammasome in Streptococcus pneumoniae Infection In Vitro and In Vivo

Dongyi Xu, Xingping Wu, Lianci Peng, Tingting Chen, Qingyuan Huang, Yu Wang, Chao Ye, Yuanyi Peng, Dongliang Hu, Rendong Fang

Int J Mol Sci. 2021 Apr; 22(8): 3876. Published online 2021 Apr 8. doi: 10.3390/ijms22083876

PMCID:: PMC8069100

Abstract Article PDF–3.0M

Select item 790052611.

Intestinal Dysbiosis Amplifies Acetaminophen-Induced Acute Liver Injury

Kai Markus Schneider, Carsten Elfers, Ahmed Ghallab, Carolin Victoria Schneider, Eric J.C. Galvez, Antje Mohs, Wenfang Gui, Lena Susanna Candels, Theresa Hildegard Wirtz, Sebastian Zuehlke, Michael Spiteller, Maiju Myllys, Alain Roulet, Amirouche Ouzerdine, Benjamin Lelouvier, Konrad Kilic, Lijun Liao, Anika Nier, Eicke Latz, Ina Bergheim, Christoph A. Thaiss, Jan G. Hengstler, Till Strowig, Christian Trautwein

Cell Mol Gastroenterol Hepatol. 2021; 11(4): 909–933. Published online 2020 Nov 12. doi: 10.1016/j.jcmgh.2020.11.002

PMCID:: PMC7900526

Abstract Article PDF–6.2M

Select item 788629812.

Microbiota-modulated CART⁺ enteric neurons autonomously regulate blood glucose

Paul A. Muller, Fanny Matheis, Marc Schneeberger, Zachary Kerner, Veronica Jové, Daniel Mucida

Science. Author manuscript; available in PMC 2021 Apr 16.

Published in final edited form as: Science. 2020 Oct 16; 370(6514): 314–321. Published online 2020 Aug 27. doi: 10.1126/science.abd6176

PMCID:: PMC7886298

Abstract Article PDF–1.9M

Select item 788144313.

Deubiquitination of NLRP6 inflammasome by Cyld critically regulates intestinal inflammation

Sandip Mukherjee, Ritesh Kumar, Elviche Tsakem Lenou, Venkatesha Basrur, Dimitris L. Kontoyiannis, Fotis Ioakeimidis, George Mosialos, Arianne L. Theiss, Richard A. Flavell, K. Venuprasad

Nat Immunol. Author manuscript; available in PMC 2021 Feb 13.

Published in final edited form as: Nat Immunol. 2020 Jun; 21(6): 626–635. Published online 2020 May 18. doi: 10.1038/s41590-020-0681-x

PMCID:: PMC7881443

Abstract Article PDF–3.3M

Select item 781274514.

The intestinal parasite Cryptosporidium is controlled by an enterocyte intrinsic inflammasome that depends on NLRP6

Adam Sateriale, Jodi A. Gullicksrud, Julie B. Engiles, Briana I. McLeod, Emily M. Kugler, Jorge Henao-Mejia, Ting Zhou, Aaron M. Ring, Igor E. Brodsky, Christopher A. Hunter, Boris Striepen

Proc Natl Acad Sci U S A. 2021 Jan 12; 118(2): e2007807118. Published online 2020 Dec 28. doi: 10.1073/pnas.2007807118

PMCID:: PMC7812745

Abstract Article PDF–1.4M

Select item 777278015.

Tissue-selective alternate promoters guide NLRP6 expression

Nathan A Bracey, Jaye M Platnich, Arthur Lau, Hyunjae Chung, M Eric Hyndman, Justin A MacDonald, Justin Chun, Paul L Beck, Stephen E Girardin, Paul MK Gordon, Daniel A Muruve

Life Sci Alliance. 2021 Mar; 4(3): e202000897. Published online 2020 Dec 29. doi: 10.26508/lsa.202000897

PMCID:: PMC7772780

Abstract Article PDF–2.6M

Select item 741409716.

The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis

Sho Kitamoto, Hiroko Nagao-Kitamoto, Yizu Jiao, Merritt G. Gillilland, III, Atsushi Hayashi, Jin Imai, Kohei Sugihara, Mao Miyoshi, Jennifer C. Brazil, Peter Kuffa, Brett D. Hill, Syed M. Rizvi, Fei Wen, Shrinivas Bishu, Naohiro Inohara, Kathryn A. Eaton, Asma Nusrat, Yu L. Lei, William V. Giannobile, Nobuhiko Kamada

Cell. Author manuscript; available in PMC 2021 Jul 23.

Published in final edited form as: Cell. 2020 Jul 23; 182(2): 447–462.e14. Published online 2020 Jun 16. doi: 10.1016/j.cell.2020.05.048

PMCID:: PMC7414097

Abstract Article PDF–4.8M

Select item 729827517.

miR-331-3p Inhibits Inflammatory Response after Intracerebral Hemorrhage by Directly Targeting NLRP6

Hao Nie, Yang Hu, Wenliang Guo, Wenzhi Wang, Qingwu Yang, Qiang Dong, Yuping Tang, Qi Li, Zhouping Tang

Biomed Res Int. 2020; 2020: 6182464. Published online 2020 Jun 7. doi: 10.1155/2020/6182464

PMCID:: PMC7298275

Abstract Article PDF–3.2M

Select item 727182118.

Adrenergic signaling in muscularis macrophages limits infection-induced neuronal loss

Fanny Matheis, Paul A. Muller, Christina L. Graves, Ilana Gabanyi, Zachary J. Kerner, Diego Costa-Borges, Tomasz Ahrends, Philip Rosenstiel, Daniel Mucida

Cell. Author manuscript; available in PMC 2021 Jan 9.

Published in final edited form as: Cell. 2020 Jan 9; 180(1): 64–78.e16. doi: 10.1016/j.cell.2019.12.002

PMCID:: PMC7271821

Abstract Article PDF–2.6M

Select item 721473119.

NLRP6 Plays an Important Role in Early Hepatic Immunopathology Caused by Schistosoma mansoni Infection

Rodrigo C. O. Sanches, Cláudia Souza, Fabio Vitarelli Marinho, Fábio Silva Mambelli, Suellen B. Morais, Erika S. Guimarães, Sergio Costa Oliveira

Front Immunol. 2020; 11: 795. Published online 2020 May 5. doi: 10.3389/fimmu.2020.00795

PMCID:: PMC7214731

Abstract Article PDF–3.1M

Select item 682959620.

The Nlrp6 inflammasome is not required for baseline colonic inner mucus layer formation or function

Joana K. Volk, Elisabeth E.L. Nyström, Sjoerd van der Post, Beatriz M. Abad, Bjoern O. Schroeder, Åsa Johansson, Frida Svensson, Sofia Jäverfelt, Malin E.V. Johansson, Gunnar C. Hansson, George M.H. Birchenough

J Exp Med. 2019 Nov 4; 216(11): 2602–2618. Published online 2019 Aug 16. doi: 10.1084/jem.20190679

PMCID:: PMC6829596

Abstract Article PDF–4.1M

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