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Select item 112909701.

Inhibition of endothelial histone deacetylase 2 shifts endothelial-mesenchymal transitions in cerebral arteriovenous malformation models

Yan Zhao, Xiuju Wu, Yang Yang, Li Zhang, Xinjiang Cai, Sydney Chen, Abigail Vera, Jaden Ji, Kristina I. Boström, Yucheng Yao

J Clin Invest. 2024 Aug 1; 134(15): e176758. Published online 2024 May 23. doi: 10.1172/JCI176758

PMCID:: PMC11290970

Abstract Article PDF–2.2M

Select item 109614282.

Attenuation of neuronal ferroptosis in intracerebral hemorrhage by inhibiting HDAC1/2: Microglial heterogenization via the Nrf2/HO1 pathway

Zhiwen Jiang, Heng Yang, Wei Ni, Xinjie Gao, Xu Pei, Hanqiang Jiang, Jiabin Su, Ruiyuan Weng, Yuchao Fei, Yanqin Gao, Yuxiang Gu

CNS Neurosci Ther. 2024 Mar; 30(3): e14646. Published online 2024 Mar 24. doi: 10.1111/cns.14646

PMCID:: PMC10961428

Abstract Article PDF–25M

Select item 108538943.

Gut microbiota regulates hepatic ischemia–reperfusion injury‐induced cognitive dysfunction via the HDAC2‐ACSS2 axis in mice

Yanbo Liu, Zhen Li, Tianning Sun, Zhixiao Li, Anne Manyande, Hongbing Xiang, Zhigang He

CNS Neurosci Ther. 2024 Feb; 30(2): e14610. Published online 2024 Feb 9. doi: 10.1111/cns.14610

PMCID:: PMC10853894

Abstract Article PDF–6.2M

Select item 108046254.

HDAC1/2 control mesothelium/ovarian cancer adhesive interactions impacting on Talin-1-α5β1-integrin-mediated actin cytoskeleton and extracellular matrix protein remodeling

Michela Terri, Pilar Sandoval, Giulio Bontempi, Claudia Montaldo, Henar Tomero-Sanz, Valeria de Turris, Flavia Trionfetti, Lucía Pascual-Antón, Irene Clares-Pedrero, Cecilia Battistelli, Sergio Valente, Clemens Zwergel, Antonello Mai, Laura Rosanò, Miguel Ángel del Pozo, Miguel Sánchez-Álvarez, Carlos Cabañas, Marco Tripodi, Manuel López-Cabrera, Raffaele Strippoli

J Exp Clin Cancer Res. 2024; 43: 27. Published online 2024 Jan 23. doi: 10.1186/s13046-023-02930-8

PMCID:: PMC10804625

Abstract Article PDF–7.7M

Select item 104154065.

Hdac1 and Hdac2 regulate the quiescent state and survival of hair-follicle mesenchymal niche

Hadas Sibony-Benyamini, Emil Aamar, David Enshell-Seijffers

Nat Commun. 2023; 14: 4820. Published online 2023 Aug 10. doi: 10.1038/s41467-023-40573-7

PMCID:: PMC10415406

Abstract Article PDF–26M

Select item 101166766.

Ovulatory signal-triggered chromatin remodeling in ovarian granulosa cells by HDAC2 phosphorylation activation-mediated histone deacetylation

Jiamin Jin, Peipei Ren, Xiang Li, Yinyi Zhang, Weijie Yang, Yerong Ma, Mengru Lai, Chao Yu, Songying Zhang, Yin-Li Zhang

Epigenetics Chromatin. 2023; 16: 11. Published online 2023 Apr 19. doi: 10.1186/s13072-023-00485-8

PMCID:: PMC10116676

Abstract Article PDF–14M

Select item 101033117.

Cell Cycle and Senescence Regulation by Podocyte Histone Deacetylase 1 and 2

Paulina X. Medina Rangel, Elizabeth Cross, Chang Liu, Christopher E. Pedigo, Xuefei Tian, Elena Gutiérrez-Calabrés, Soichiro Nagata, Anupama Priyadarshini, Gabriel Lerner, Patricia Bunda, Sudhir Perincheri, Jianlei Gu, Hongyu Zhao, Ying Wang, Kazunori Inoue, Shuta Ishibe

J Am Soc Nephrol. 2023 Mar; 34(3): 433–450. Published online 2022 Nov 22. doi: 10.1681/ASN.2022050598

PMCID:: PMC10103311

Abstract Article

Select item 97328328.

HDAC2 in Primary Sensory Neurons Constitutively Restrains Chronic Pain by Repressing α2δ-1 Expression and Associated NMDA Receptor Activity

Jixiang Zhang, Shao-Rui Chen, Meng-Hua Zhou, Daozhong Jin, Hong Chen, Li Wang, Ronald A. DePinho, Hui-Lin Pan

J Neurosci. 2022 Nov 30; 42(48): 8918–8935. doi: 10.1523/JNEUROSCI.0735-22.2022

PMCID:: PMC9732832

Abstract Article PDF–6.3M

Select item 96067229.

O-fucosylation of thrombospondin type 1 repeats is essential for ECM remodeling and signaling during bone development

Sanjiv Neupane, Steven J. Berardinelli, Daniel C. Cameron, Richard C. Grady, David E. Komatsu, Christopher J. Percival, Megumi Takeuchi, Atsuko Ito, Ta-Wei Liu, Alison V. Nairn, Kelley W. Moremen, Robert S. Haltiwanger, Bernadette C. Holdener

Matrix Biol. Author manuscript; available in PMC 2022 Oct 27.

Published in final edited form as: Matrix Biol. 2022 Mar; 107: 77–96. Published online 2022 Feb 12. doi: 10.1016/j.matbio.2022.02.002

PMCID:: PMC9606722

Abstract Article PDF–6.7M

Select item 960442810.

Mother–Fetus Immune Cross-Talk Coordinates “Extrinsic”/“Intrinsic” Embryo Gene Expression Noise and Growth Stability

Tatyana Ivanovna Babochkina, Ludmila Alekseevna Gerlinskaya, Margarita Vladimirovna Anisimova, Galina Vladimirovna Kontsevaya, Natalia Aleksandrovna Feofanova, Aliya Konstantinovna Stanova, Mikhail Pavlovich Moshkin, Yuri Mikhailovich Moshkin

Int J Mol Sci. 2022 Oct; 23(20): 12467. Published online 2022 Oct 18. doi: 10.3390/ijms232012467

PMCID:: PMC9604428

Abstract Article PDF–2.3M

Select item 940915911.

Smoking Cessation in Mice Does Not Switch off Persistent Lung Inflammation and Does Not Restore the Expression of HDAC2 and SIRT1

Giovanna De Cunto, Simone De Meo, Barbara Bartalesi, Eleonora Cavarra, Giuseppe Lungarella, Monica Lucattelli

Int J Mol Sci. 2022 Aug; 23(16): 9104. Published online 2022 Aug 14. doi: 10.3390/ijms23169104

PMCID:: PMC9409159

Abstract Article PDF–6.2M

Select item 935971812.

HDAC2 Facilitates Pancreatic Cancer Metastasis

Lukas Krauß, Bettina C. Urban, Sieglinde Hastreiter, Carolin Schneider, Patrick Wenzel, Zonera Hassan, Matthias Wirth, Katharina Lankes, Andrea Terrasi, Christine Klement, Filippo M. Cernilogar, Rupert Öllinger, Niklas de Andrade Krätzig, Thomas Engleitner, Roland M. Schmid, Katja Steiger, Roland Rad, Oliver H. Krämer, Maximilian Reichert, Gunnar Schotta, Dieter Saur, Günter Schneider

Cancer Res. 2022 Feb 15; 82(4): 695–707. Published online 2021 Dec 13. doi: 10.1158/0008-5472.CAN-20-3209

PMCID:: PMC9359718

Abstract Article PDF–1.2M

Select item 879184513.

Kidney cell type-specific changes in the chromatin and transcriptome landscapes following epithelial Hdac1 and Hdac2 knockdown

Kelly A. Hyndman, David K. Crossman

Physiol Genomics. 2022 Feb 1; 54(2): 45–57. Published online 2021 Dec 10. doi: 10.1152/physiolgenomics.00102.2021

PMCID:: PMC8791845

Abstract Article

Select item 876331714.

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1–CoREST interactome during embryonic stem cell differentiation

Claire E. Barnes, David M. English, Megan Broderick, Mark O. Collins, Shaun M. Cowley

Mol Omics. 2022 Jan 17; 18(1): 31–44. Published online 2021 Oct 14. doi: 10.1039/d1mo00236h

PMCID:: PMC8763317

Abstract Article

Select item 868828615.

HDAC1/2 control proliferation and survival in adult epidermis and pre-basal cell carcinoma via p16 and p53

Xuming Zhu, Matthew Leboeuf, Fang Liu, Marina Grachtchouk, John T. Seykora, Edward E. Morrisey, Andrzej A. Dlugosz, Sarah E. Millar

J Invest Dermatol. Author manuscript; available in PMC 2023 Jan 1.

Published in final edited form as: J Invest Dermatol. 2022 Jan; 142(1): 77–87.e10. Published online 2021 Jul 18. doi: 10.1016/j.jid.2021.05.026

PMCID:: PMC8688286

Abstract Article PDF–1.3M

Select item 837315416.

PWWP2B Fine‐Tunes Adipose Thermogenesis by Stabilizing HDACs in a NuRD Subcomplex

Linyu Yan, Weiwei Jin, Qingwen Zhao, Xuan Cui, Ting Shi, Yingjiang Xu, Feiyan Li, Wenfang Jin, Zhe Zhang, Zhao Zhang, Qi‐Qun Tang, Dongning Pan

Adv Sci (Weinh) 2021 Aug; 8(16): 2102060. Published online 2021 Jun 27. doi: 10.1002/advs.202102060

PMCID:: PMC8373154

Abstract Article PDF–4.5M

Select item 831573817.

RP58 Represses Transcriptional Programs Linked to Nonneuronal Cell Identity and Glioblastoma Subtypes in Developing Neurons

Chaomei Xiang, Karla K. Frietze, Yingtao Bi, Yanwen Li, Valentina Dal Pozzo, Sharmistha Pal, Noah Alexander, Valerie Baubet, Victoria D’Acunto, Christopher E. Mason, Ramana V. Davuluri, Nadia Dahmane

Mol Cell Biol. 2021 Jul; 41(7): e00526-20. Prepublished online 2021 Apr 26. Published online 2021 Jun 23. doi: 10.1128/MCB.00526-20

PMCID:: PMC8315738

Abstract Article PDF–7.7M

Select item 808431618.

Small Extracellular Vesicles Control Dendritic Spine Development through Regulation of HDAC2 Signaling

Longbo Zhang, Tiffany V. Lin, Qianying Yuan, Remy Sadoul, TuKiet T. Lam, Angélique Bordey

J Neurosci. 2021 Apr 28; 41(17): 3799–3807. doi: 10.1523/JNEUROSCI.0766-20.2021

PMCID:: PMC8084316

Abstract Article PDF–2.0M

Select item 807968619.

HDAC2 targeting stabilizes the CoREST complex in renal tubular cells and protects against renal ischemia/reperfusion injury

David D. Aufhauser, Jr., Paul Hernandez, Seth J. Concors, Ciaran O’Brien, Zhonglin Wang, Douglas R. Murken, Arabinda Samanta, Ulf H. Beier, Lauren Krumeich, Tricia R. Bhatti, Yanfeng Wang, Guanghui Ge, Liqing Wang, Shayan Cheraghlou, Florence F. Wagner, Edward B. Holson, Jay H. Kalin, Philip A. Cole, Wayne W. Hancock, Matthew H. Levine

Sci Rep. 2021; 11: 9018. Published online 2021 Apr 27. doi: 10.1038/s41598-021-88242-3

PMCID:: PMC8079686

Abstract Article PDF–8.1M

Select item 804530020.

Hdac1 and Hdac2 are essential for physiological maturation of a Cx3cr1 expressing subset of T-lymphocytes

Moumita Datta, Ori Staszewski

BMC Res Notes. 2021; 14: 135. Published online 2021 Apr 13. doi: 10.1186/s13104-021-05551-6

PMCID:: PMC8045300

Abstract Article PDF–7.3M

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