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Select item 93485761.

Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease

Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel

Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205

PMCID:: PMC9348576

Abstract Article PDF–3.0M

Select item 90123212.

Synaptic Kalirin-7 and Trio Interactomes Reveal a GEF Protein-Dependent Neuroligin-1 Mechanism of Action

Jeremiah D. Paskus, Chen Tian, Erin Fingleton, Christine Shen, Xiaobing Chen, Yan Li, Samuel A. Myers, John D. Badger, II, Michael A. Bemben, Bruce E. Herring, Katherine W. Roche

Cell Rep. Author manuscript; available in PMC 2022 Apr 15.

Published in final edited form as: Cell Rep. 2019 Dec 3; 29(10): 2944–2952.e5. doi: 10.1016/j.celrep.2019.10.115

PMCID:: PMC9012321

Abstract Article PDF–1.8M

Select item 89068073.

The m⁶A reader YTHDF2 is a negative regulator for dendrite development and maintenance of retinal ganglion cells

Fugui Niu, Peng Han, Jian Zhang, Yuanchu She, Lixin Yang, Jun Yu, Mengru Zhuang, Kezhen Tang, Yuwei Shi, Baisheng Yang, Chunqiao Liu, Bo Peng, Sheng-Jian Ji

eLife. 2022; 11: e75827. Published online 2022 Feb 18. doi: 10.7554/eLife.75827

PMCID:: PMC8906807

Abstract Article PDF–14M

Select item 86940554.

A Kalirin missense mutation enhances dendritic RhoA signaling and leads to regression of cortical dendritic arbors across development

Melanie J. Grubisha, Tao Sun, Leanna Eisenman, Susan L. Erickson, Shinny-yi Chou, Cassandra D. Helmer, Melody T. Trudgen, Ying Ding, Gregg E. Homanics, Peter Penzes, Zachary P. Wills, Robert A. Sweet

Proc Natl Acad Sci U S A. 2021 Dec 7; 118(49): e2022546118. Published online 2021 Nov 30. doi: 10.1073/pnas.2022546118

PMCID:: PMC8694055

Abstract Article PDF–2.9M

Select item 83132395.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 80988146.

The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis

Shalini Menon, Dennis Goldfarb, Chris T. Ho, Erica W. Cloer, Nicholas P. Boyer, Christopher Hardie, Andrew J. Bock, Emma C. Johnson, Joel Anil, M. Ben Major, Stephanie L. Gupton

Mol Biol Cell. 2021 Feb 15; 32(4): 314–330. doi: 10.1091/mbc.E20-10-0622

PMCID:: PMC8098814

Abstract Article PDF–7.7M

Select item 79387707.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 78797118.

Rapid 3D Enhanced Resolution Microscopy Reveals Diversity in Dendritic Spinule Dynamics, Regulation, and Function

Colleen R. Zaccard, Lauren Shapiro, Maria D. Martin-de-Saavedra, Christopher Pratt, Kristoffer Myczek, Amy Song, Marc P. Forrest, Peter Penzes

Neuron. Author manuscript; available in PMC 2021 Feb 12.

Published in final edited form as: Neuron. 2020 Aug 5; 107(3): 522–537.e6. Published online 2020 May 27. doi: 10.1016/j.neuron.2020.04.025

PMCID:: PMC7879711

Abstract Article PDF–3.6M

Select item 76094559.

Role of Kalirin and Mouse Strain in Retention of Spatial Memory Training in an Alzheimer’s Disease Model Mouse Line

Lillian Russo-Savage, Vishwanatha K.S. Rao, Betty A. Eipper, Richard E. Mains

Neurobiol Aging. Author manuscript; available in PMC 2021 Nov 1.

Published in final edited form as: Neurobiol Aging. 2020 Nov; 95: 69–80. Published online 2020 Jul 14. doi: 10.1016/j.neurobiolaging.2020.07.006

PMCID:: PMC7609455

Abstract Article PDF–2.0M

Select item 754947910.

KALRN mutations promote antitumor immunity and immunotherapy response in cancer

Mengyuan Li, Yuxiang Ma, You Zhong, Qian Liu, Canping Chen, Lei Qiang, Xiaosheng Wang

J Immunother Cancer. 2020; 8(2): e000293. Published online 2020 Oct 9. doi: 10.1136/jitc-2019-000293

PMCID:: PMC7549479

Abstract Article PDF–5.9M

Select item 669277011.

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics

Joel D. Federspiel, Todd M. Greco, Krystal K. Lum, Ileana M. Cristea

Mol Cell Proteomics. 2019 Aug 9; 18(8 Suppl 1): S92–S113. Published online 2019 Apr 30. doi: 10.1074/mcp.RA118.001253

PMCID:: PMC6692770

Abstract Article PDF–7.7M

Select item 596422812.

The COOH-terminal domain of huntingtin interacts with RhoGEF kalirin and modulates cell survival

Hollis McClory, Xiaolong Wang, Ellen Sapp, Leah W. Gatune, Maria Iuliano, Chiu-Yi Wu, Gina Nathwani, Kimberly B. Kegel-Gleason, Marian DiFiglia, Xueyi Li

Sci Rep. 2018; 8: 8000. Published online 2018 May 22. doi: 10.1038/s41598-018-26255-1

PMCID:: PMC5964228

Abstract Article PDF–1.9M

Select item 576395213.

Kalirin-7 is a Key Player in the Formation of Excitatory Synapses in Hippocampal Neurons

Xin-Ming Ma

ScientificWorldJournal. 2010; 10: 1655–1666. Published online 2010 Aug 17. doi: 10.1100/tsw.2010.148

PMCID:: PMC5763952

Abstract PDF–731K

Select item 565867114.

The transcription factor XBP1s restores hippocampal synaptic plasticity and memory by control of the Kalirin-7 pathway in Alzheimer model

M Cissé, E Duplan, T Lorivel, J Dunys, C Bauer, X Meckler, Y Gerakis, I Lauritzen, F Checler

Mol Psychiatry. 2017 Nov; 22(11): 1562–1575. Published online 2016 Sep 20. doi: 10.1038/mp.2016.152

PMCID:: PMC5658671

Abstract Article PDF–780K

Select item 564508215.

Spatio-temporal profile of postynaptic interactomes integrates components of complex brain disorders

Jing Li, Wangshu Zhang, Hui Yang, Daniel P. Howrigan, Brent Wilkinson, Tade Souaiaia, Oleg V. Evgrafov, Giulio Genovese, Veronica A. Clementel, Jennifer C. Tudor, Ted Abel, James A. Knowles, Benjamin M. Neale, Kai Wang, Fengzhu Sun, Marcelo P. Coba

Nat Neurosci. Author manuscript; available in PMC 2018 Aug 1.

Published in final edited form as: Nat Neurosci. 2017 Aug; 20(8): 1150–1161. Published online 2017 Jun 26. doi: 10.1038/nn.4594