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Items: 1 to 20 of 299

1.
IGF2 deficiency promotes liver aging through mitochondrial dysfunction and upregulated CEBPB signaling in d-galactose-induced aging mice
Xiaohai Zhou, Bowen Tan, Weiwei Gui, Caiping Zhou, Hanxin Zhao, Xihua Lin, Hong Li
Mol Med. 2023; 29: 161. Published online 2023 Nov 28. doi: 10.1186/s10020-023-00752-0
PMCID:
PMC10685569
AbstractArticlePDF–13M
2.
TMED10 mediates the trafficking of insulin-like growth factor 2 along the secretory pathway for myoblast differentiation
Tiantian Li, Feng Yang, Youshan Heng, Shaopu Zhou, Gang Wang, Jianying Wang, Jinhui Wang, Xianwei Chen, Zhong-Ping Yao, Zhenguo Wu, Yusong Guo
Proc Natl Acad Sci U S A. 2023 Nov 14; 120(46): e2215285120. Published online 2023 Nov 6. doi: 10.1073/pnas.2215285120
PMCID:
PMC10655563
AbstractArticlePDF–9.9M
3.
Disturbance of suprachiasmatic nucleus function improves cardiac repair after myocardial infarction by IGF2-mediated macrophage transition
Kai-li Hao, Qiao-cheng Zhai, Yue Gu, Yue-qiu Chen, Ya-ning Wang, Rui Liu, Shi-ping Yan, Ying Wang, Yu-fang Shi, Wei Lei, Zhen-ya Shen, Ying Xu, Shi-jun Hu
Acta Pharmacol Sin. 2023 Aug; 44(8): 1612–1624. Published online 2023 Feb 6. doi: 10.1038/s41401-023-01059-w
PMCID:
PMC10374569
AbstractArticlePDF–6.3M
4.
Overexpression of IGF2 affects mouse weight and glycolipid metabolism and IGF2 is positively related to macrosomia
Qidi Zhang, Shengtang Qin, Jing Huai, Huixia Yang, Yumei Wei
Front Endocrinol (Lausanne) 2023; 14: 1030453. Published online 2023 Apr 19. doi: 10.3389/fendo.2023.1030453
PMCID:
PMC10154688
AbstractArticlePDF–3.3M
5.
Identification of IGF2 as Genomic Driver and Actionable Therapeutic Target in Hepatoblastoma
Jordi Abril-Fornaguera, Laura Torrens, Carmen Andreu-Oller, Juan Carrillo-Reixach, Alex Rialdi, Ugne Balaseviciute, Roser Pinyol, Carla Montironi, Philipp K. Haber, Álvaro Del Río-Álvarez, Montserrat Domingo-Sàbat, Laura Royo, Nicholas K. Akers, Catherine E. Willoughby, Judit Peix, Miguel Torres-Martin, Marc Puigvehi, Stefano Cairo, Margaret Childs, Rudolf Maibach, Rita Alaggio, Piotr Czauderna, Bruce Morland, Bojan Losic, Vincenzo Mazzaferro, Ernesto Guccione, Daniela Sia, Carolina Armengol, Josep M. Llovet
Mol Cancer Ther. Author manuscript; available in PMC 2023 Oct 3.
Published in final edited form as: Mol Cancer Ther. 2023 Apr 3; 22(4): 485–498. doi: 10.1158/1535-7163.MCT-22-0335
PMCID:
PMC10073300
AbstractArticlePDF–1.8M
6.
Characterization of placental endocrine function and fetal brain development in a mouse model of small for gestational age
Jorge Lopez-Tello, Amanda N. Sferruzzi-Perri
Front Endocrinol (Lausanne) 2023; 14: 1116770. Published online 2023 Feb 10. doi: 10.3389/fendo.2023.1116770
PMCID:
PMC9950515
AbstractArticlePDF–4.2M
7.
PRL2 phosphatase enhances oncogenic FLT3 signaling via dephosphorylation of the E3 ubiquitin ligase CBL at tyrosine 371
Hongxia Chen, Yunpeng Bai, Michihiro Kobayashi, Shiyu Xiao, Wenjie Cai, Sergio Barajas, Sisi Chen, Jinmin Miao, Frederick Nguele Meke, Sasidhar Vemula, James P. Ropa, James M. Croop, H. Scott Boswell, Jun Wan, Yuzhi Jia, Huiping Liu, Loretta S. Li, Jessica K. Altman, Elizabeth A. Eklund, Peng Ji, Wei Tong, Hamid Band, Danny T. Huang, Leonidas C. Platanias, Zhong-Yin Zhang, Yan Liu
Blood. 2023 Jan 19; 141(3): 244–259. Published online 2022 Oct 11. doi: 10.1182/blood.2022016580
Correction in:
Blood. 2024 Jan 25; 143(4): 376.
PMCID:
PMC9936309
AbstractArticle
8.
IGF2 interacts with the imprinted gene Cdkn1c to promote terminal differentiation of neural stem cells
Anna Lozano-Ureña, Laura Lázaro-Carot, Esteban Jiménez-Villalba, Raquel Montalbán-Loro, Isabel Mateos-White, Pere Duart-Abadía, Irene Martínez-Gurrea, Keiichi I. Nakayama, Isabel Fariñas, Martina Kirstein, Cristina Gil-Sanz, Sacri R. Ferrón
Development. 2023 Jan 1; 150(1): dev200563. Published online 2023 Jan 12. doi: 10.1242/dev.200563
PMCID:
PMC9903205
AbstractArticle
9.
Noncanonical regulation of imprinted gene Igf2 by amyloid-beta 1–42 in Alzheimer’s disease
Emre Fertan, William H. Gendron, Aimée A. Wong, Gabrielle M. Hanson, Richard E. Brown, Ian C. G. Weaver
Sci Rep. 2023; 13: 2043. Published online 2023 Feb 4. doi: 10.1038/s41598-023-29248-x
PMCID:
PMC9899226
AbstractArticlePDF–2.3M
10.
Hepatic ribosomal protein S6 (Rps6) insufficiency results in failed bile duct development and loss of hepatocyte viability; a ribosomopathy-like phenotype that is partially p53-dependent
Sarah A. Comerford, Elizabeth A. Hinnant, Yidong Chen, Robert E. Hammer
PLoS Genet. 2023 Jan; 19(1): e1010595. Published online 2023 Jan 19. doi: 10.1371/journal.pgen.1010595
PMCID:
PMC9888725
AbstractArticlePDF–6.9M
11.
Loss of IGF2 gene imprinting in murine prostate promotes widespread neoplastic growth
Nathan A. Damaschke, Bing Yang, Sachin Bhusari, Mele Avilla, Weixiong Zhong, Michael L. Blute, Jr., Wei Huang, David F. Jarrard
Cancer Res. Author manuscript; available in PMC 2022 Dec 11.
Published in final edited form as: Cancer Res. 2017 Oct 1; 77(19): 5236–5247. Published online 2017 Aug 3. doi: 10.1158/0008-5472.CAN-16-3089
PMCID:
PMC9741865
AbstractArticlePDF–2.1M
12.
Dysregulated H19/Igf2 expression disrupts cardiac-placental axis during development of Silver-Russell syndrome-like mouse models
Suhee Chang, Diana Fulmer, Stella K Hur, Joanne L Thorvaldsen, Li Li, Yemin Lan, Eric A Rhon-Calderon, Nicolae Adrian Leu, Xiaowen Chen, Jonathan A Epstein, Marisa S Bartolomei
eLife. 2022; 11: e78754. Published online 2022 Nov 28. doi: 10.7554/eLife.78754
PMCID:
PMC9704805
AbstractArticlePDF–20M
13.
Paternal obesity induces placental hypoxia and sex-specific impairments in placental vascularization and offspring metabolism
Patrycja A Jazwiec, Violet S Patterson, Tatiane A Ribeiro, Erica Yeo, Katherine M Kennedy, Paulo C F Mathias, Jim J Petrik, Deborah M Sloboda
Biol Reprod. 2022 Aug; 107(2): 574–589. Published online 2022 Apr 4. doi: 10.1093/biolre/ioac066
PMCID:
PMC9382389
AbstractArticlePDF–1.7M
14.
Spatiotemporal single-cell regulatory atlas reveals neural crest lineage diversification and cellular function during tooth morphogenesis
Junjun Jing, Jifan Feng, Yuan Yuan, Tingwei Guo, Jie Lei, Fei Pei, Thach-Vu Ho, Yang Chai
Nat Commun. 2022; 13: 4803. Published online 2022 Aug 16. doi: 10.1038/s41467-022-32490-y
PMCID:
PMC9381504
AbstractArticlePDF–6.6M
15.
Placental structure, function, and mitochondrial phenotype relate to fetal size in each fetal sex in mice
Esteban Salazar-Petres, Daniela Pereira-Carvalho, Jorge Lopez-Tello, Amanda Nancy Sferruzzi-Perri
Biol Reprod. 2022 Jun; 106(6): 1292–1311. Published online 2022 Mar 16. doi: 10.1093/biolre/ioac056
PMCID:
PMC9327737
AbstractArticlePDF–3.0M
16.
Hepatocyte Deletion of IGF2 Prevents DNA Damage and Tumor Formation in Hepatocellular Carcinoma
Deepak Kumar, Manasi Das, Alexis Oberg, Debashis Sahoo, Panyisha Wu, Consuelo Sauceda, Lily Jih, Lesley G. Ellies, Magda T. Langiewicz, Supriya Sen, Nicholas J. G. Webster
Adv Sci (Weinh) 2022 Jul; 9(21): 2105120. Published online 2022 May 26. doi: 10.1002/advs.202105120
PMCID:
PMC9313545
AbstractArticlePDF–7.7M
17.
Transcriptional Profiling of Insulin-like Growth Factor Signaling Components in Embryonic Lung Development and Idiopathic Pulmonary Fibrosis
Vahid Kheirollahi, Ali Khadim, Georgios Kiliaris, Martina Korfei, Margarida Maria Barroso, Ioannis Alexopoulos, Ana Ivonne Vazquez-Armendariz, Malgorzata Wygrecka, Clemens Ruppert, Andreas Guenther, Werner Seeger, Susanne Herold, Elie El Agha
Cells. 2022 Jun; 11(12): 1973. Published online 2022 Jun 20. doi: 10.3390/cells11121973
PMCID:
PMC9221724
AbstractArticlePDF–128M
18.
The Effects of Maternal Intake of EPA and DHA Enriched Diet During Pregnancy and Lactation on Offspring’s Muscle Development and Energy Homeostasis
Saeed Ghnaimawi, Shilei Zhang, Jamie I. Baum, Yan Huang
Front Physiol. 2022; 13: 881624. Published online 2022 Jun 6. doi: 10.3389/fphys.2022.881624
PMCID:
PMC9207413
AbstractArticlePDF–6.0M
19.
Astroblastomas exhibit radial glia stem cell lineages and differential expression of imprinted and X-inactivation escape genes
Norman L. Lehman, Nathalie Spassky, Müge Sak, Amy Webb, Cory T. Zumbar, Aisulu Usubalieva, Khaled J. Alkhateeb, Joseph P. McElroy, Kirsteen H. Maclean, Paolo Fadda, Tom Liu, Vineela Gangalapudi, Jamie Carver, Zied Abdullaev, Cynthia Timmers, John R. Parker, Christopher R. Pierson, Bret C. Mobley, Murat Gokden, Eyas M. Hattab, Timothy Parrett, Ralph X. Cooke, Trang D. Lehman, Stefan Costinean, Anil Parwani, Brian J. Williams, Randy L. Jensen, Kenneth Aldape, Akshitkumar M. Mistry
Nat Commun. 2022; 13: 2083. Published online 2022 Apr 19. doi: 10.1038/s41467-022-29302-8
Correction in:
Nat Commun. 2023; 14: 507.
PMCID:
PMC9018799
AbstractArticlePDF–5.5M
20.
Hepatic IGF2/H19 Epigenetic Alteration Induced Glucose Intolerance in Gestational Diabetes Mellitus Offspring via FoxO1 Mediation
Ying Jiang, Hong Zhu, Zi Chen, Yi-Chen Yu, Xiao-Han Guo, Yuan Chen, Meng-Meng Yang, Bang-Wu Chen, Matthew Sagnelli, Dong Xu, Bai-Hui Zhao, Qiong Luo
Front Endocrinol (Lausanne) 2022; 13: 844707. Published online 2022 Apr 1. doi: 10.3389/fendo.2022.844707
PMCID:
PMC9011096
AbstractArticlePDF–1.5M

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