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Select item 66751731.

Glial Cell Line-Derived Neurotrophic Factor-Dependent Recruitment of Ret into Lipid Rafts Enhances Signaling by Partitioning Ret from Proteasome-Dependent Degradation

Brian A. Pierchala, Jeffrey Milbrandt, Eugene M. Johnson, Jr

J Neurosci. 2006 Mar 8; 26(10): 2777–2787. doi: 10.1523/JNEUROSCI.3420-05.2006

PMCID:: PMC6675173

Abstract Article PDF–857K

Select item 52909522.

Signal Transducer and Activator of Transcription 1 Plays a Pivotal Role in RET/PTC3 Oncogene-induced Expression of Indoleamine 2,3-Dioxygenase 1

Sonia Moretti, Elisa Menicali, Nicole Nucci, Pasquale Voce, Renato Colella, Rosa Marina Melillo, Federica Liotti, Silvia Morelli, Francesca Fallarino, Antonio Macchiarulo, Massimo Santoro, Nicola Avenia, Efisio Puxeddu

J Biol Chem. 2017 Feb 3; 292(5): 1785–1797. Published online 2016 Dec 19. doi: 10.1074/jbc.M116.745448

PMCID:: PMC5290952

Abstract Article PDF–1.7M

Select item 49655733.

Exon Skipping in the RET Gene Encodes Novel Isoforms That Differentially Regulate RET Protein Signal Transduction

Nicole A. Gabreski, Janki K. Vaghasia, Silvia S. Novakova, Neil Q. McDonald, Brian A. Pierchala

J Biol Chem. 2016 Jul 29; 291(31): 16249–16262. Published online 2016 May 23. doi: 10.1074/jbc.M115.709675

PMCID:: PMC4965573

Abstract Article PDF–2.9M

Select item 40458064.

RET Variants and Haplotype Analysis in a Cohort of Czech Patients with Hirschsprung Disease

Eliska Vaclavikova, Sarka Dvorakova, Richard Skaba, Lucie Pos, Vlasta Sykorova, Tereza Halkova, Josef Vcelak, Bela Bendlova

PLoS One. 2014; 9(6): e98957. Published online 2014 Jun 4. doi: 10.1371/journal.pone.0098957

PMCID:: PMC4045806

Abstract Article PDF–331K

Select item 38447765.

CD2AP and Cbl-3/Cbl-c Constitute a Critical Checkpoint in the Regulation of Ret Signal Transduction

Cynthia C. Tsui, Brian A. Pierchala

J Neurosci. 2008 Aug 27; 28(35): 8789–8800. doi: 10.1523/JNEUROSCI.2738-08.2008

PMCID:: PMC3844776

Abstract Article PDF–806K

Select item 35819546.

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins

Rajesh Ghai, Andrea Bugarcic, Huadong Liu, Suzanne J. Norwood, Sune Skeldal, Elizabeth J. Coulson, Shawn Shun-Cheng Li, Rohan D. Teasdale, Brett M. Collins

Proc Natl Acad Sci U S A. 2013 Feb 19; 110(8): E643–E652. Published online 2013 Feb 4. doi: 10.1073/pnas.1216229110

PMCID:: PMC3581954

Abstract Article PDF–2.3M

Select item 32658747.

Identification of a Key Motif That Determines the Differential Surface Levels of RET and TrkB Tyrosine Kinase Receptors and Controls Depolarization Enhanced RET Surface Insertion

Xue-Zhi Li, Jing Yan, Shu-Hong Huang, Ling Zhao, Jue Wang, Zhe-Yu Chen

J Biol Chem. 2012 Jan 13; 287(3): 1932–1945. Published online 2011 Nov 29. doi: 10.1074/jbc.M111.283457

PMCID:: PMC3265874

Abstract Article PDF–3.0M

Select item 32598858.

The Structure of the Glial Cell Line-derived Neurotrophic Factor-Coreceptor Complex: INSIGHTS INTO RET SIGNALING AND HEPARIN BINDING

Vimal Parkash, Veli-Matti Leppänen, Heidi Virtanen, Jaana M. Jurvansuu, Maxim M. Bespalov, Yulia A. Sidorova, Pia Runeberg-Roos, Mart Saarma, Adrian Goldman

J Biol Chem. 2008 Dec 12; 283(50): 35164–35172. doi: 10.1074/jbc.M802543200

PMCID:: PMC3259885

Abstract Article PDF–673K

Select item 31934429.

Rap1GAP interacts with RET and suppresses GDNF-induced neurite outgrowth

Li Jiao, Yong Zhang, Chun Hu, Yong-Gang Wang, Aijun Huang, Cheng He

Cell Res. 2011 Feb; 21(2): 327–337. Published online 2010 Sep 28. doi: 10.1038/cr.2010.139

PMCID:: PMC3193442

Abstract Article PDF–904K

Select item 317805910.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 308230811.

Nephric duct insertion is a crucial step in urinary tract maturation that is regulated by a Gata3-Raldh2-Ret molecular network in mice

Ian Chia, David Grote, Michael Marcotte, Ekaterina Batourina, Cathy Mendelsohn, Maxime Bouchard

Development. 2011 May 15; 138(10): 2089–2097. doi: 10.1242/dev.056838

PMCID:: PMC3082308

Abstract Article

Select item 307766012.

RET Modulates Cell Adhesion via Its Cleavage by Caspase in Sympathetic Neurons

Jorge R. Cabrera, Jimena Bouzas-Rodriguez, Servane Tauszig-Delamasure, Patrick Mehlen

J Biol Chem. 2011 Apr 22; 286(16): 14628–14638. Published online 2011 Feb 28. doi: 10.1074/jbc.M110.195461

PMCID:: PMC3077660

Abstract Article PDF–2.2M

Select item 295125813.

Protein-tyrosine Phosphatase SHP2 Contributes to GDNF Neurotrophic Activity through Direct Binding to Phospho-Tyr⁶⁸⁷ in the RET Receptor Tyrosine Kinase

Maurice Perrinjaquet, Marçal Vilar, Carlos F. Ibáñez

J Biol Chem. 2010 Oct 8; 285(41): 31867–31875. Published online 2010 Aug 3. doi: 10.1074/jbc.M110.144923

PMCID:: PMC2951258

Abstract Article PDF–2.2M

Select item 286017614.

The Differential Axonal Degradation of Ret Accounts for Cell-Type-Specific Function of Glial Cell Line-Derived Neurotrophic Factor as a Retrograde Survival Factor

Cynthia C. Tsui, Brian A. Pierchala

J Neurosci. 2010 Apr 14; 30(15): 5149–5158. doi: 10.1523/JNEUROSCI.5246-09.2010

PMCID:: PMC2860176

Abstract Article PDF–1.2M

Select item 285028215.

RET Signaling Is Required for Survival and Normal Function of Nonpeptidergic Nociceptors

Judith P. Golden, Masato Hoshi, Mohammed A. Nassar, Hideki Enomoto, John N. Wood, Jeffrey Milbrandt, Robert W. Gereau, IV, Eugene M. Johnson, Jr, Sanjay Jain

J Neurosci. 2010 Mar 17; 30(11): 3983–3994. doi: 10.1523/JNEUROSCI.5930-09.2010

PMCID:: PMC2850282

Abstract Article PDF–2.7M

Select item 261407816.

Hirschsprung Disease Is Linked to Defects in Neural Crest Stem Cell Function

Toshihide Iwashita, Genevieve M. Kruger, Ricardo Pardal, Mark J. Kiel, Sean J. Morrison

Science. Author manuscript; available in PMC 2009 Jan 6.

Published in final edited form as: Science. 2003 Aug 15; 301(5635): 972–976. doi: 10.1126/science.1085649

PMCID:: PMC2614078

Abstract Article PDF–1.2M

Select item 255157717.

A Common RET Variant Is Associated with Reduced Newborn Kidney Size and Function

Zhao Zhang, Jackie Quinlan, Wendy Hoy, Michael D. Hughson, Mathieu Lemire, Thomas Hudson, Pierre-Alain Hueber, Alice Benjamin, Anne Roy, Elena Pascuet, Meigan Goodyer, Chandhana Raju, Fiona Houghton, John Bertram, Paul Goodyer

J Am Soc Nephrol. 2008 Oct; 19(10): 2027–2034. doi: 10.1681/ASN.2007101098

PMCID:: PMC2551577

Abstract Article

Select item 217245318.

The neuronal scaffold protein Shank3 mediates signaling and biological function of the receptor tyrosine kinase Ret in epithelial cells

Gunnar Schuetz, Marta Rosário, Jan Grimm, Tobias M. Boeckers, Eckart D. Gundelfinger, Walter Birchmeier

J Cell Biol. 2004 Dec 6; 167(5): 945–952. doi: 10.1083/jcb.200404108

PMCID:: PMC2172453

Abstract Article PDF–1.6M

Select item 185277419.

The dependence receptor Ret induces apoptosis in somatotrophs through a Pit-1/p53 pathway, preventing tumor growth

Carmen Cañibano, Noela L Rodriguez, Carmen Saez, Sulay Tovar, Montse Garcia-Lavandeira, Maria Grazia Borrello, Anxo Vidal, Frank Costantini, Miguel Japon, Carlos Dieguez, Clara V Alvarez

EMBO J. 2007 Apr 18; 26(8): 2015–2028. Published online 2007 Mar 22. doi: 10.1038/sj.emboj.7601636