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Select item 109915531.

Dbf4-dependent kinase promotes cell cycle controlled resection of DNA double-strand breaks and repair by homologous recombination

Lorenzo Galanti, Martina Peritore, Robert Gnügge, Elda Cannavo, Johannes Heipke, Maria Dilia Palumbieri, Barbara Steigenberger, Lorraine S. Symington, Petr Cejka, Boris Pfander

Nat Commun. 2024; 15: 2890. Published online 2024 Apr 3. doi: 10.1038/s41467-024-46951-z

PMCID:: PMC10991553

Abstract Article PDF–4.7M

Select item 108724772.

Protein interaction network revealed by quantitative proteomic analysis links TFIIB to multiple aspects of the transcription cycle

Michael J. O’Brien, Athar Ansari

Biochim Biophys Acta Proteins Proteom. Author manuscript; available in PMC 2024 Feb 16.

Published in final edited form as: Biochim Biophys Acta Proteins Proteom. 2024 Jan 1; 1872(1): 140968. Published online 2023 Oct 19. doi: 10.1016/j.bbapap.2023.140968

PMCID:: PMC10872477

Abstract Article PDF–1.7M

Select item 107911533.

Persistent Acetylation of Histone H3 Lysine 56 Compromises the Activity of DNA Replication Origins

Roch Tremblay, Yosra Mehrjoo, Oumaima Ahmed, Antoine Simoneau, Mary E. McQuaid, El Bachir Affar, Corey Nislow, Guri Giaever, Hugo Wurtele

Mol Cell Biol. 2023; 43(11): 566–595. Published online 2023 Nov 17. doi: 10.1080/10985549.2023.2259739

PMCID:: PMC10791153

Abstract Article PDF–4.0M

Select item 107835004.

The Efg1–Bud22 dimer associates with the U14 snoRNP contacting the 5′ rRNA domain of an early 90S pre-ribosomal particle

Olga Beine-Golovchuk, Martina Kallas, Ruth Kunze, Sabine Griesel, Jochen Baßler

Nucleic Acids Res. 2024 Jan 11; 52(1): 431–447. Published online 2023 Nov 24. doi: 10.1093/nar/gkad1109

PMCID:: PMC10783500

Abstract Article PDF–2.3M

Select item 107001385.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 105517006.

Misregulation of cell cycle-dependent methylation of budding yeast CENP-A contributes to chromosomal instability

Prashant K. Mishra, Wei-Chun Au, Pedro G. Castineira, Nazrin Ali, John Stanton, Lars Boeckmann, Yoshimitsu Takahashi, Michael Costanzo, Charles Boone, Kerry S. Bloom, Peter H. Thorpe, Munira A. Basrai

Mol Biol Cell. 2023 Sep 1; 34(10): ar99. Published online 2023 Aug 17. doi: 10.1091/mbc.E23-03-0108

PMCID:: PMC10551700

Abstract Article PDF–3.7M

Select item 99923157.

Multi-site phosphorylation of yeast Mif2/CENP-C promotes inner kinetochore assembly

Stephen M. Hinshaw, Yun Quan, Jiaxi Cai, Ann L. Zhou, Huilin Zhou

Curr Biol. Author manuscript; available in PMC 2024 Feb 27.

Published in final edited form as: Curr Biol. 2023 Feb 27; 33(4): 688–696.e6. Published online 2023 Feb 2. doi: 10.1016/j.cub.2023.01.012

PMCID:: PMC9992315

Abstract Article PDF–2.0M

Select item 92860238.

Mediator recruits the cohesin loader Scc2 to RNA Pol II-transcribed genes and promotes sister chromatid cohesion

Mark Mattingly, Chris Seidel, Sofía Muñoz, Yan Hao, Ying Zhang, Zhihui Wen, Laurence Florens, Frank Uhlmann, Jennifer L. Gerton

Curr Biol. 2022 Jul 11; 32(13): 2884–2896.e6. doi: 10.1016/j.cub.2022.05.019

PMCID:: PMC9286023

Abstract Article

Select item 92098119.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 913311210.

The structural basis of Cdc7-Dbf4 kinase dependent targeting and phosphorylation of the MCM2-7 double hexamer

Almutasem Saleh, Yasunori Noguchi, Ricardo Aramayo, Marina E. Ivanova, Kathryn M. Stevens, Alex Montoya, S. Sunidhi, Nicolas Lopez Carranza, Marcin J. Skwark, Christian Speck

Nat Commun. 2022; 13: 2915. Published online 2022 May 25. doi: 10.1038/s41467-022-30576-1

PMCID:: PMC9133112

Abstract Article PDF–7.2M

Select item 892711711.

Structural Insight into the MCM double hexamer activation by Dbf4-Cdc7 kinase

Jiaxuan Cheng, Ningning Li, Yunjing Huo, Shangyu Dang, Bik-Kwoon Tye, Ning Gao, Yuanliang Zhai

Nat Commun. 2022; 13: 1396. Published online 2022 Mar 16. doi: 10.1038/s41467-022-29070-5

Correction in:: Nat Commun. 2022; 13: 2411.

PMCID:: PMC8927117

Abstract Article PDF–6.6M

Select item 877013112.

Structural mechanism for the selective phosphorylation of DNA-loaded MCM double hexamers by the Dbf4-dependent kinase

Julia F. Greiwe, Thomas C. R. Miller, Julia Locke, Fabrizio Martino, Steven Howell, Anne Schreiber, Andrea Nans, John F. X. Diffley, Alessandro Costa

Nat Struct Mol Biol. 2022; 29(1): 10–20. Published online 2021 Dec 28. doi: 10.1038/s41594-021-00698-z

PMCID:: PMC8770131

Abstract Article PDF–12M

Select item 869396813.

Cdc7-mediated phosphorylation of Cse4 regulates high-fidelity chromosome segregation in budding yeast

Prashant K. Mishra, Henry Wood, John Stanton, Wei-Chun Au, Jessica R. Eisenstatt, Lars Boeckmann, Robert A. Sclafani, Michael Weinreich, Kerry S. Bloom, Peter H. Thorpe, Munira A. Basrai

Mol Biol Cell. 2021 Nov 1; 32(21): ar15. doi: 10.1091/mbc.E21-06-0323

PMCID:: PMC8693968

Abstract Article PDF–3.3M

Select item 857069314.

Phosphorylation of luminal region of the SUN-domain protein Mps3 promotes nuclear envelope localization during meiosis

Hanumanthu BD Prasada Rao, Takeshi Sato, Kiran Challa, Yurika Fujita, Miki Shinohara, Akira Shinohara

eLife. 2021; 10: e63119. Published online 2021 Sep 29. doi: 10.7554/eLife.63119

PMCID:: PMC8570693

Abstract Article PDF–4.7M

Select item 838702315.

Rad53 checkpoint kinase regulation of DNA replication fork rate via Mrc1 phosphorylation

Allison W McClure, John FX Diffley

eLife. 2021; 10: e69726. Published online 2021 Aug 13. doi: 10.7554/eLife.69726

PMCID:: PMC8387023

Abstract Article PDF–4.9M

Select item 772018316.

Exo1 recruits Cdc5 polo kinase to MutLγ to ensure efficient meiotic crossover formation

Aurore Sanchez, Céline Adam, Felix Rauh, Yann Duroc, Lepakshi Ranjha, Bérangère Lombard, Xiaojing Mu, Mélody Wintrebert, Damarys Loew, Alba Guarné, Stefano Gnan, Chun-Long Chen, Scott Keeney, Petr Cejka, Raphaël Guérois, Franz Klein, Jean-Baptiste Charbonnier, Valérie Borde

Proc Natl Acad Sci U S A. 2020 Dec 1; 117(48): 30577–30588. Published online 2020 Nov 16. doi: 10.1073/pnas.2013012117

PMCID:: PMC7720183

Abstract Article PDF–2.3M

Select item 771875117.

Comprehensive Synthetic Genetic Array Analysis of Alleles That Interact with Mutation of the Saccharomyces cerevisiae RecQ Helicases Hrq1 and Sgs1

Elsbeth Sanders, Phoebe A. Nguyen, Cody M. Rogers, Matthew L. Bochman

G3 (Bethesda) 2020 Dec; 10(12): 4359–4368. Published online 2020 Oct 28. doi: 10.1534/g3.120.401709

PMCID:: PMC7718751

Abstract Article PDF–1.2M

Select item 737142418.

The role of Rif1 in telomere length regulation is separable from its role in origin firing

Calla B Shubin, Carol W Greider

eLife. 2020; 9: e58066. Published online 2020 Jun 29. doi: 10.7554/eLife.58066

PMCID:: PMC7371424

Abstract Article PDF–2.7M

Select item 728916019.

Regulated proteolysis of MutSγ controls meiotic crossing over

Wei He, H.B.D. Prasada Rao, Shangming Tang, Nikhil Bhagwat, Dhananjaya S. Kulkarni, Yunmei Ma, Maria A.W. Chang, Christie Hall, Junxi Wang-Bragg, Harrison S. Manasca, Christa Baker, Gerrik F. Verhees, Lepakshi Ranjha, Xiangyu Chen, Nancy M. Hollingsworth, Petr Cejka, Neil Hunter

Mol Cell. Author manuscript; available in PMC 2020 Jun 11.

Published in final edited form as: Mol Cell. 2020 Apr 2; 78(1): 168–183.e5. Published online 2020 Mar 3. doi: 10.1016/j.molcel.2020.02.001

PMCID:: PMC7289160

Abstract Article PDF–1.3M

Select item 726367520.

Dbf4-Dependent Kinase (DDK)-Mediated Proteolysis of CENP-A Prevents Mislocalization of CENP-A in Saccharomyces cerevisiae

Jessica R. Eisenstatt, Lars Boeckmann, Wei-Chun Au, Valerie Garcia, Levi Bursch, Josefina Ocampo, Michael Costanzo, Michael Weinreich, Robert A. Sclafani, Anastasia Baryshnikova, Chad L. Myers, Charles Boone, David J. Clark, Richard Baker, Munira A. Basrai

G3 (Bethesda) 2020 Jun; 10(6): 2057–2068. Published online 2020 Apr 15. doi: 10.1534/g3.120.401131