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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 93887752.

Anthrax toxins regulate pain signaling and can deliver molecular cargoes into Antxr2⁺ DRG sensory neurons

Nicole J. Yang, Jörg Isensee, Dylan Neel, Andreza U. Quadros, Han-Xiong Bear Zhang, Justas Lauzadis, Sai Man Liu, Stephanie Shiers, Andreea Belu, Shilpa Palan, Sandra Marlin, Jacquie Maignel, Angela Kennedy-Curran, Victoria S. Tong, Mahtab Moayeri, Pascal Röderer, Anja Nitzsche, Mike Lu, Bradley L. Pentelute, Oliver Brüstle, Vineeta Tripathi, Keith A. Foster, Theodore J. Price, R. John Collier, Stephen H. Leppla, Michelino Puopolo, Bruce P. Bean, Thiago M. Cunha, Tim Hucho, Isaac M. Chiu

Nat Neurosci. Author manuscript; available in PMC 2022 Aug 19.

Published in final edited form as: Nat Neurosci. 2022 Feb; 25(2): 168–179. Published online 2021 Dec 20. doi: 10.1038/s41593-021-00973-8

PMCID:: PMC9388775

Abstract Article PDF–4.7M

Select item 92506163.

Capillary Morphogenesis gene 2 (CMG2) mediates growth factor-induced angiogenesis by regulating endothelial cell chemotaxis

Lorna M. Cryan, Tsz-Ming Tsang, Jessica Stiles, Lauren Bazinet, Sai Lun Lee, Samuel Garrard, Erika Madrian, Cody Roberts, Jessie Payne, Andrew Jensen, Arthur E. Frankel, P. Christine Ackroyd, Kenneth A. Christensen, Michael S. Rogers

Angiogenesis. Author manuscript; available in PMC 2023 Aug 1.

Published in final edited form as: Angiogenesis. 2022 Aug; 25(3): 397–410. Published online 2022 Feb 25. doi: 10.1007/s10456-022-09833-w

PMCID:: PMC9250616

Abstract Article PDF–1.7M

Select item 87163334.

Imaging of anthrax intoxication in mice reveals shared and individual functions of surface receptors CMG-2 and TEM-8 in cellular toxin entry

Carly Merritt, Elizabeth M. Chun, Rasem J. Fattah, Lakmali M. Silva, Quinn Q. Ma, Mahtab Moayeri, Dennis Paliga, Sebastian Neumann, Rolf Heumann, Stephen H. Leppla, Thomas H. Bugge

J Biol Chem. 2022 Jan; 298(1): 101467. Published online 2021 Dec 4. doi: 10.1016/j.jbc.2021.101467

PMCID:: PMC8716333

Abstract Article PDF–6.5M

Select item 83699255.

Nociceptive Sensory Neurons Mediate Inflammation Induced by Bacillus Anthracis Edema Toxin

Nicole J. Yang, Dylan V. Neel, Liwen Deng, Michelle Heyang, Angela Kennedy-Curran, Victoria S. Tong, Jin Mo Park, Isaac M. Chiu

Front Immunol. 2021; 12: 642373. Published online 2021 Aug 3. doi: 10.3389/fimmu.2021.642373

PMCID:: PMC8369925

Abstract Article PDF–2.9M

Select item 83157386.

RP58 Represses Transcriptional Programs Linked to Nonneuronal Cell Identity and Glioblastoma Subtypes in Developing Neurons

Chaomei Xiang, Karla K. Frietze, Yingtao Bi, Yanwen Li, Valentina Dal Pozzo, Sharmistha Pal, Noah Alexander, Valerie Baubet, Victoria D’Acunto, Christopher E. Mason, Ramana V. Davuluri, Nadia Dahmane

Mol Cell Biol. 2021 Jul; 41(7): e00526-20. Prepublished online 2021 Apr 26. Published online 2021 Jun 23. doi: 10.1128/MCB.00526-20

PMCID:: PMC8315738

Abstract Article PDF–7.7M

Select item 74159917.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 54727808.

CMG2/ANTXR2 regulates extracellular collagen VI which accumulates in hyaline fibromatosis syndrome

Jérôme Bürgi, Béatrice Kunz, Laurence Abrami, Julie Deuquet, Alessandra Piersigilli, Sabine Scholl-Bürgi, Ekkehart Lausch, Sheila Unger, Andrea Superti-Furga, Paolo Bonaldo, F. Gisou van der Goot

Nat Commun. 2017; 8: 15861. Published online 2017 Jun 12. doi: 10.1038/ncomms15861

PMCID:: PMC5472780

Abstract Article PDF–5.7M

Select item 50639859.

Anthrax Toxin Protective Antigen Variants That Selectively Utilize either the CMG2 or TEM8 Receptors for Cellular Uptake and Tumor Targeting

Kuang-Hua Chen, Shihui Liu, Clinton E. Leysath, Sharmina Miller-Randolph, Yi Zhang, Rasem Fattah, Thomas H. Bugge, Stephen H. Leppla

J Biol Chem. 2016 Oct 14; 291(42): 22021–22029. Published online 2016 Aug 23. doi: 10.1074/jbc.M116.753301

PMCID:: PMC5063985

Abstract Article PDF–338K

Select item 494834510.

Solid tumor therapy by selectively targeting stromal endothelial cells

Shihui Liu, Jie Liu, Qian Ma, Liu Cao, Rasem J. Fattah, Zuxi Yu, Thomas H. Bugge, Toren Finkel, Stephen H. Leppla

Proc Natl Acad Sci U S A. 2016 Jul 12; 113(28): E4079–E4087. Published online 2016 Jun 29. doi: 10.1073/pnas.1600982113

PMCID:: PMC4948345

Abstract Article PDF–1.1M

Select item 414092711.

Targeted Silencing of Anthrax Toxin Receptors Protects against Anthrax Toxins

Maria T. Arévalo, Ashley Navarro, Chenoa D. Arico, Junwei Li, Omar Alkhatib, Shan Chen, Diana Diaz-Arévalo, Mingtao Zeng

J Biol Chem. 2014 May 30; 289(22): 15730–15738. Published online 2014 Apr 17. doi: 10.1074/jbc.M113.538587

PMCID:: PMC4140927

Abstract Article PDF–1.1M

Select item 408030512.

Key tissue targets responsible for anthrax toxin-induced-lethality

Shihui Liu, Yi Zhang, Mahtab Moayeri, Jie Liu, Devorah Crown, Rasem Fattah, Alexander N. Wein, Zu-Xi Yu, Toren Finkel, Stephen H. Leppla

Nature. Author manuscript; available in PMC 2014 Sep 5.

Published in final edited form as: Nature. 2013 Sep 5; 501(7465): 63–68. Published online 2013 Aug 28. doi: 10.1038/nature12510

PMCID:: PMC4080305

Abstract Article PDF–2.6M

Select item 368376813.

CCT chaperonin complex is required for efficient delivery of anthrax toxin into the cytosol of host cells

Louise H. Slater, Erik C. Hett, Anne E. Clatworthy, Kevin G. Mark, Deborah T. Hung

Proc Natl Acad Sci U S A. 2013 Jun 11; 110(24): 9932–9937. Published online 2013 May 28. doi: 10.1073/pnas.1302257110

PMCID:: PMC3683768

Abstract Article PDF–488K

Select item 357241014.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 356837215.

Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration

Stephen Lumayag, Caroline E. Haldin, Nicola J. Corbett, Karl J. Wahlin, Colleen Cowan, Sanja Turturro, Peter E. Larsen, Beatrix Kovacs, P. Dane Witmer, David Valle, Donald J. Zack, Daniel A. Nicholson, Shunbin Xu

Proc Natl Acad Sci U S A. 2013 Feb 5; 110(6): E507–E516. Published online 2013 Jan 22. doi: 10.1073/pnas.1212655110

PMCID:: PMC3568372

Abstract Article PDF–2.1M

Select item 337670816.

Capillary morphogenesis protein-2 is required for mouse parturition by maintaining uterine collagen homeostasis

Diane E. Peters, Yi Zhang, Alfredo A. Molinolo, Sharmina Miller-Randolph, Roman Szabo, Thomas H. Bugge, Stephen H. Leppla, Shihui Liu

Biochem Biophys Res Commun. Author manuscript; available in PMC 2013 Jun 8.

Published in final edited form as: Biochem Biophys Res Commun. 2012 Jun 8; 422(3): 393–397. Published online 2012 May 7. doi: 10.1016/j.bbrc.2012.04.160