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Items: 1 to 20 of 40

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Targeting of RRM2 suppresses DNA damage response and activates apoptosis in atypical teratoid rhabdoid tumor
Le Hien Giang, Kuo-Sheng Wu, Wei-Chung Lee, Shing-Shung Chu, Anh Duy Do, Chun A. Changou, Huy Minh Tran, Tsung-Han Hsieh, Hsin-Hung Chen, Chia-Ling Hsieh, Shian-Ying Sung, Alice L. Yu, Yun Yen, Tai-Tong Wong, Che-Chang Chang
J Exp Clin Cancer Res. 2023; 42: 346. Published online 2023 Dec 20. doi: 10.1186/s13046-023-02911-x
PMCID:
PMC10731702
AbstractArticlePDF–5.0M
3.
Yap is essential for uterine decidualization through Rrm2/GSH/ROS pathway in response to Bmp2
Hai-Fan Yu, Zhan-Qing Yang, Ming-Yue Xu, Ji-Cheng Huang, Zhan-Peng Yue, Bin Guo
Int J Biol Sci. 2022; 18(6): 2261–2276. Published online 2022 Mar 6. doi: 10.7150/ijbs.67756
PMCID:
PMC8990470
AbstractArticlePDF–3.0M
4.
RRM2 Alleviates Doxorubicin-Induced Cardiotoxicity through the AKT/mTOR Signaling Pathway
Yuheng Jiao, Yanyan Li, Jiayan Zhang, Song Zhang, Yafang Zha, Jian Wang
Biomolecules. 2022 Feb; 12(2): 299. Published online 2022 Feb 12. doi: 10.3390/biom12020299
PMCID:
PMC8869767
AbstractArticlePDF–5.8M
5.
Molecular Profiling Reveals Involvement of ESCO2 in Intermediate Progenitor Cell Maintenance in the Developing Mouse Cortex
Pauline Antonie Ulmke, M. Sadman Sakib, Peter Ditte, Godwin Sokpor, Cemil Kerimoglu, Linh Pham, Yuanbin Xie, Xiaoyi Mao, Joachim Rosenbusch, Ulrike Teichmann, Huu Phuc Nguyen, Andre Fischer, Gregor Eichele, Jochen F. Staiger, Tran Tuoc
Stem Cell Reports. 2021 Apr 13; 16(4): 968–984. Published online 2021 Apr 1. doi: 10.1016/j.stemcr.2021.03.008
PMCID:
PMC8072132
AbstractArticlePDF–8.1M
6.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
AbstractArticlePDF–2.0M
7.
Cdh1-APC Regulates Protein Synthesis and Stress Granules in Neurons through an FMRP-Dependent Mechanism
Arielle N. Valdez-Sinon, Austin Lai, Liang Shi, Carly L. Lancaster, Avanti Gokhale, Victor Faundez, Gary J. Bassell
iScience. 2020 May 22; 23(5): 101132. Published online 2020 May 1. doi: 10.1016/j.isci.2020.101132
PMCID:
PMC7236060
AbstractArticlePDF–6.1M
8.
An Immunocompetent Mouse Model of HPV16(+) Head and Neck Squamous Cell Carcinoma
Miranda B. Carper, Scott Troutman, Bethany L. Wagner, Kevin M. Byrd, Sara R. Selitsky, Kshitij Parag-Sharma, Erin C. Henry, Weimin Li, Joel S. Parker, Stephanie A. Montgomery, John L. Cleveland, Scott E. Williams, Joseph L. Kissil, David N. Hayes, Antonio L. Amelio
Cell Rep. Author manuscript; available in PMC 2019 Nov 21.
Published in final edited form as: Cell Rep. 2019 Nov 5; 29(6): 1660–1674.e7. doi: 10.1016/j.celrep.2019.10.005
PMCID:
PMC6870917
AbstractArticlePDF–3.1M
9.
Asxl1 exerts an antiproliferative effect on mouse lung maturation via epigenetic repression of the E2f1-Nmyc axis
Seungtae Moon, Sun-Kyoung Im, Nackhyoung Kim, Hyesook Youn, Ui-Hyun Park, Joo-Yeon Kim, A.-Reum Kim, So-Jung An, Ji-Hoon Kim, Woong Sun, Jin-Taek Hwang, Eun-Joo Kim, Soo-Jong Um
Cell Death Dis. 2018 Nov; 9(11): 1118. Published online 2018 Nov 2. doi: 10.1038/s41419-018-1171-z
PMCID:
PMC6215009
AbstractArticlePDF–2.7M
10.
Temporal requirements for ISL1 in sympathetic neuron proliferation, differentiation, and diversification
Qingquan Zhang, Ru Huang, Youqiong Ye, Xiaoxia Guo, Jun Lu, Fugui Zhu, Xiaohui Gong, Qitong Zhang, Jie Yan, Lina Luo, Shaowei Zhuang, Yihan Chen, Xiaodong Zhao, Sylvia M. Evans, Cizhong Jiang, Xingqun Liang, Yunfu Sun
Cell Death Dis. 2018 Feb; 9(2): 247. Published online 2018 Feb 14. doi: 10.1038/s41419-018-0283-9
PMCID:
PMC5833373
AbstractArticlePDF–4.6M
11.
Repression of interstitial identity in nephron progenitor cells by Pax2 establishes the nephron-interstitium boundary throughout kidney development
Natalie Naiman, Kaoru Fujioka, Mari Fujino, M. Todd Valerius, S. Steven Potter, Andrew P. McMahon, Akio Kobayashi
Dev Cell. Author manuscript; available in PMC 2018 May 22.
Published in final edited form as: Dev Cell. 2017 May 22; 41(4): 349–365.e3. doi: 10.1016/j.devcel.2017.04.022
PMCID:
PMC5532731
AbstractArticlePDF–1.9M
12.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
13.
Detection of differentially expressed candidate genes for a fatty liver QTL on mouse chromosome 12
Misato Kobayashi, Miyako Suzuki, Tamio Ohno, Kana Tsuzuki, Chie Taguchi, Soushi Tateishi, Teruo Kawada, Young-il Kim, Atsushi Murai, Fumihiko Horio
BMC Genet. 2016; 17: 73. Published online 2016 Jun 6. doi: 10.1186/s12863-016-0385-2
PMCID:
PMC4895971
AbstractArticlePDF–775K
14.
Oocyte-expressed yes-associated protein is a key activator of the early zygotic genome in mouse
Chao Yu, Shu-Yan Ji, Yu-Jiao Dang, Qian-Qian Sha, Yi-Feng Yuan, Jian-Jie Zhou, Li-Ying Yan, Jie Qiao, Fuchou Tang, Heng-Yu Fan
Cell Res. 2016 Mar; 26(3): 275–287. Published online 2016 Feb 23. doi: 10.1038/cr.2016.20
PMCID:
PMC4783469
AbstractArticlePDF–9.2M
15.
A Single Conserved Residue Mediates Binding of the Ribonucleotide Reductase Catalytic Subunit RRM1 to RRM2 and Is Essential for Mouse Development
Julia Specks, Emilio Lecona, Andrés J. Lopez-Contreras, Oscar Fernandez-Capetillo
Mol Cell Biol. 2015 Sep; 35(17): 2910–2917. Prepublished online 2015 Jun 15. Published online 2015 Aug 4. doi: 10.1128/MCB.00475-15
PMCID:
PMC4525308
AbstractArticlePDF–1.1M
16.
Increased Rrm2 gene dosage reduces fragile site breakage and prolongs survival of ATR mutant mice
Andres J. Lopez-Contreras, Julia Specks, Jacqueline H. Barlow, Chiara Ambrogio, Claus Desler, Svante Vikingsson, Sara Rodrigo-Perez, Henrik Green, Lene Juel Rasmussen, Matilde Murga, André Nussenzweig, Oscar Fernandez-Capetillo
Genes Dev. 2015 Apr 1; 29(7): 690–695. doi: 10.1101/gad.256958.114
PMCID:
PMC4387711
AbstractArticlePDF–489K
17.
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson
Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977
PMCID:
PMC3964955
AbstractArticlePDF–5.7M
18.
Ribonucleotide Reductase Expression in Cervix Cancer: a Radiation Therapy Oncology Group Translational Science Analysis
Charles A. Kunos, Kathryn Winter, Adam P. Dicker, William Small, Jr., Fadi W. Abdul-Karim, Dawn Dawson, Anuja Jhingran, Richard Valicenti, Joanne B. Weidhaas, David K. Gaffney
Int J Gynecol Cancer. Author manuscript; available in PMC 2014 May 1.
Published in final edited form as: Int J Gynecol Cancer. 2013 May; 23(4): 615–621. doi: 10.1097/IGC.0b013e31828b4eb5
PMCID:
PMC3662019
AbstractArticlePDF–946K
19.
Transgenic overexpression of ribonucleotide reductase improves cardiac performance
Sarah G. Nowakowski, Stephen C. Kolwicz, Frederick Steven Korte, Zhaoxiong Luo, Jacqueline N. Robinson-Hamm, Jennifer L. Page, Frank Brozovich, Robert S. Weiss, Rong Tian, Charles E. Murry, Michael Regnier
Proc Natl Acad Sci U S A. 2013 Apr 9; 110(15): 6187–6192. Published online 2013 Mar 25. doi: 10.1073/pnas.1220693110
PMCID:
PMC3625337
AbstractArticlePDF–332K
20.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M

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