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Select item 114992561.

Two-factor authentication underpins the precision of the piRNA pathway

Madeleine Dias Mirandela, Ansgar Zoch, Jessica Leismann, Shaun Webb, Rebecca V. Berrens, Devisree Valsakumar, Yuka Kabayama, Tania Auchynnikava, Martina Schito, Tamoghna Chowdhury, David MacLeod, Xinyu Xiang, Juan Zou, Juri Rappsilber, Robin C. Allshire, Philipp Voigt, Atlanta G. Cook, Joan Barau, Dónal O’Carroll

Nature. 2024; 634(8035): 979–985. Published online 2024 Sep 18. doi: 10.1038/s41586-024-07963-3

PMCID:: PMC11499256

Abstract Article PDF–23M

Select item 113806892.

PHD2 safeguards modest mesendoderm development

Meng Li, Huaizhang Jin, Yun Zhao, Guoping Zhu, Yu Liu, Hongan Long, Xiaopeng Shen

Commun Biol. 2024; 7: 1100. Published online 2024 Sep 7. doi: 10.1038/s42003-024-06824-z

PMCID:: PMC11380689

Abstract Article PDF–4.1M

Select item 112903223.

The primitive endoderm supports lineage plasticity to enable regulative development

Madeleine Linneberg-Agerholm, Annika Charlotte Sell, Alba Redó-Riveiro, Marta Perera, Martin Proks, Teresa E. Knudsen, Antonio Barral, Miguel Manzanares, Joshua M. Brickman

Cell. 2024 Jul 25; 187(15): 4010–4029.e16. doi: 10.1016/j.cell.2024.05.051

PMCID:: PMC11290322

Abstract Article

Select item 111905794.

Smad4 is essential for epiblast scaling and morphogenesis after implantation, but nonessential before implantation

Robin E. Kruger, Tristan Frum, A. Sophie Brumm, Stephanie L. Hickey, Kathy K. Niakan, Farina Aziz, Marcelio A. Shammami, Jada G. Roberts, Amy Ralston

Development. 2024 Jun 1; 151(11): dev202377. Published online 2024 Jun 5. doi: 10.1242/dev.202377

PMCID:: PMC11190579

Abstract Article

Select item 111465905.

Oct4 redox sensitivity potentiates reprogramming and differentiation

Zuolian Shen, Yifan Wu, Asit Manna, Chongil Yi, Bradley R. Cairns, Kimberley J. Evason, Mahesh B. Chandrasekharan, Dean Tantin

Genes Dev. 2024 Apr 1; 38(7-8): 308–321. doi: 10.1101/gad.351411.123

PMCID:: PMC11146590

Abstract Article PDF–13M

Select item 109404616.

Txnip regulates the Oct4-mediated pluripotency circuitry via metabolic changes upon differentiation

Sojung Kwak, Cho Lok Song, Yee Sook Cho, Inpyo Choi, Jae-Eun Byun, Haiyoung Jung, Jungwoon Lee

Cell Mol Life Sci. 2024 Dec; 81(1): 142. Published online 2024 Mar 15. doi: 10.1007/s00018-024-05161-y

PMCID:: PMC10940461

Abstract Article PDF–3.7M

Select item 109098937.

MAX controls meiotic entry in sexually undifferentiated germ cells

Ayumu Suzuki, Kousuke Uranishi, Masazumi Nishimoto, Yosuke Mizuno, Seiya Mizuno, Satoru Takahashi, Robert N. Eisenman, Akihiko Okuda

Sci Rep. 2024; 14: 5236. Published online 2024 Mar 4. doi: 10.1038/s41598-024-55506-7

PMCID:: PMC10909893

Abstract Article PDF–7.0M

Select item 108078158.

Endogenous retroviruses shape pluripotency specification in mouse embryos

Sergio de la Rosa, María del Mar Rigual, Pierfrancesco Vargiu, Sagrario Ortega, Nabil Djouder

Sci Adv. 2024 Jan 26; 10(4): eadk9394. Published online 2024 Jan 24. doi: 10.1126/sciadv.adk9394

PMCID:: PMC10807815

Abstract Article PDF–23M

Select item 107562959.

Roles of the Rlim–Rex1 axis during X chromosome inactivation in mice

Feng Wang, Ashmita Chander, Yeonsoo Yoon, Janelle M. Welton, Mary C. Wallingford, Carmen Espejo-Serrano, Francisco Bustos, Greg M. Findlay, Jesse Mager, Ingolf Bach

Proc Natl Acad Sci U S A. 2023 Dec 26; 120(52): e2313200120. Published online 2023 Dec 19. doi: 10.1073/pnas.2313200120

PMCID:: PMC10756295

Abstract Article PDF–12M

Select item 1067216610.

Mature mRNA processing that deletes 3′ end sequences directs translational activation and embryonic development

Yuki Takada, Ludivine Fierro, Keisuke Sato, Takahiro Sanada, Anna Ishii, Takehiro Yamamoto, Tomoya Kotani

Sci Adv. 2023 Nov 24; 9(47): eadg6532. Published online 2023 Nov 24. doi: 10.1126/sciadv.adg6532

PMCID:: PMC10672166

Abstract Article PDF–2.2M

Select item 1062779511.

Smooth muscle cells-specific loss of OCT4 accelerates neointima formation after acute vascular injury

Junchul Shin, Svyatoslav Tkachenko, Delphine Gomez, Rupande Tripathi, Gary K. Owens, Olga A. Cherepanova

Front Cardiovasc Med. 2023; 10: 1276945. Published online 2023 Oct 23. doi: 10.3389/fcvm.2023.1276945

PMCID:: PMC10627795

Abstract Article PDF–6.6M

Select item 1060708912.

Regulatory Elements Outside Established Pou5f1 Gene Boundaries Are Required for Multilineage Differentiation of Embryonic Stem Cells

Veronika V. Ermakova, Nikita P. Fokin, Nikolay D. Aksenov, Evgeny I. Bakhmet, Ekaterina V. Aleksandrova, Andrey A. Kuzmin, Alexey N. Tomilin

Int J Mol Sci. 2023 Oct; 24(20): 15434. Published online 2023 Oct 21. doi: 10.3390/ijms242015434

PMCID:: PMC10607089

Abstract Article PDF–2.3M

Select item 1060047113.

Transcription and chromatin regulation by TAF4b during cellular quiescence of developing prospermatogonia

Megan A. Gura, Myles A. Bartholomew, Kimberly M. Abt, Soňa Relovská, Kimberly A. Seymour, Richard N. Freiman

Front Cell Dev Biol. 2023; 11: 1270408. Published online 2023 Oct 12. doi: 10.3389/fcell.2023.1270408

PMCID:: PMC10600471

Abstract Article PDF–4.4M

Select item 1057727814.

Rhox8 homeobox gene ablation leads to rete testis abnormality and male subfertility in mice

Yeongseok Oh, Maho Kasu, Constence J Bottoms, Jenna C Douglas, Nikola Sekulovski, Kanako Hayashi, James A MacLean II

Biol Reprod. 2023 Oct; 109(4): 520–532. Published online 2023 Jul 20. doi: 10.1093/biolre/ioad077

PMCID:: PMC10577278

Abstract Article PDF–1.9M

Select item 1050591515.

Single‐molecule tracking of Nanog and Oct4 in living mouse embryonic stem cells uncovers a feedback mechanism of pluripotency maintenance

Kazuko Okamoto, Hideaki Fujita, Yasushi Okada, Soya Shinkai, Shuichi Onami, Kuniya Abe, Kenta Fujimoto, Kensuke Sasaki, Go Shioi, Tomonobu M Watanabe

EMBO J. 2023 Sep; 42(18): e112305. Published online 2023 Aug 23. doi: 10.15252/embj.2022112305

PMCID:: PMC10505915

Abstract Article PDF–5.5M

Select item 1047617416.

Embryo‐uterine interaction coordinates mouse embryogenesis during implantation

Vladyslav Bondarenko, Mikhail Nikolaev, Dimitri Kromm, Roman Belousov, Adrian Wolny, Marloes Blotenburg, Peter Zeller, Saba Rezakhani, Johannes Hugger, Virginie Uhlmann, Lars Hufnagel, Anna Kreshuk, Jan Ellenberg, Alexander van Oudenaarden, Anna Erzberger, Matthias P Lutolf, Takashi Hiiragi

EMBO J. 2023 Sep; 42(17): e113280. Published online 2023 Jul 31. doi: 10.15252/embj.2022113280

PMCID:: PMC10476174

Abstract Article PDF–4.7M

Select item 1038712917.

RNA exosome ribonuclease DIS3 degrades Pou6f1 to promote mouse pre-implantation cell differentiation

Di Wu, Jurrien Dean

Cell Rep. Author manuscript; available in PMC 2023 Oct 23.

Published in final edited form as: Cell Rep. 2023 Feb 28; 42(2): 112047. Published online 2023 Jan 30. doi: 10.1016/j.celrep.2023.112047

PMCID:: PMC10387129

Abstract Article PDF–2.2M

Select item 1033043518.

hnRNPL Expression Dynamics in the Embryo and Placenta

Vineetha Mathew, Ariel Mei, Hamida Giwa, Agnes Cheong, Ashmita Chander, Aaron Zou, Robert M. Blanton, Olga Kashpur, Wei Cui, Donna Slonim, Taysir Mahmoud, Perrie O’Tierney-Ginn, Jesse Mager, Isabelle Draper, Mary C. Wallingford

Gene Expr Patterns. Author manuscript; available in PMC 2024 Jun 1.

Published in final edited form as: Gene Expr Patterns. 2023 Jun; 48: 119319. Published online 2023 May 4. doi: 10.1016/j.gep.2023.119319

PMCID:: PMC10330435

Abstract Article PDF–3.1M

Select item 1032904819.

Plakoglobin is a mechanoresponsive regulator of naive pluripotency

Timo N. Kohler, Joachim De Jonghe, Anna L. Ellermann, Ayaka Yanagida, Michael Herger, Erin M. Slatery, Antonia Weberling, Clara Munger, Katrin Fischer, Carla Mulas, Alex Winkel, Connor Ross, Sophie Bergmann, Kristian Franze, Kevin Chalut, Jennifer Nichols, Thorsten E. Boroviak, Florian Hollfelder

Nat Commun. 2023; 14: 4022. Published online 2023 Jul 7. doi: 10.1038/s41467-023-39515-0

PMCID:: PMC10329048

Abstract Article PDF–8.0M

Select item 1028856020.

Trophoblast PR-SET7 dysfunction induces viral mimicry response and necroptosis associated with recurrent miscarriage

Xiaobo Zhou, Yingchun Xu, Shengnan Ren, Ningjie Yang, Yang Sun, Qibing Yang, Yue Zhang, Han Cai, Wenbo Deng, Jingsi Chen, Dunjin Chen, Bin Cao, Hongbo Qi, Haibin Wang, Jinhua Lu

Proc Natl Acad Sci U S A. 2023 Jun 20; 120(25): e2216206120. Published online 2023 Jun 12. doi: 10.1073/pnas.2216206120