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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 107232232.

JAM-C Is Important for Lens Epithelial Cell Proliferation and Lens Fiber Maturation in Murine Lens Development

Qihang Sun, Jiani Li, Jingyu Ma, Yuxing Zheng, Rong Ju, Xuri Li, Xiangrong Ren, Lijuan Huang, Rongyuan Chen, Xuhua Tan, Lixia Luo

Invest Ophthalmol Vis Sci. 2023 Dec; 64(15): 15. Published online 2023 Dec 14. doi: 10.1167/iovs.64.15.15

PMCID:: PMC10723223

Abstract Article PDF–36M

Select item 101012363.

Charged multivesicular-body protein 4b forms complexes with gap-junction proteins during lens fiber cell differentiation

Yuefang Zhou, Thomas M. Bennett, Thomas W. White, Alan Shiels

FASEB J. Author manuscript; available in PMC 2023 Apr 13.

Published in final edited form as: FASEB J. 2023 Apr; 37(4): e22801. doi: 10.1096/fj.202201368RR

PMCID:: PMC10101236

Abstract Article PDF–2.8M

Select item 94966834.

Levels and Modifications of Both Lens Fiber Cell Connexins Are Affected in Connexin Mutant Mice

Oscar Jara, Peter J. Minogue, Viviana M. Berthoud, Eric C. Beyer

Cells. 2022 Sep; 11(18): 2786. Published online 2022 Sep 7. doi: 10.3390/cells11182786

PMCID:: PMC9496683

Abstract Article PDF–1.1M

Select item 76000925.

Do Connexin Mutants Cause Cataracts by Perturbing Glutathione Levels and Redox Metabolism in the Lens?

Oscar Jara, Peter J. Minogue, Viviana M. Berthoud, Eric C. Beyer

Biomolecules. 2020 Oct; 10(10): 1418. Published online 2020 Oct 7. doi: 10.3390/biom10101418

PMCID:: PMC7600092

Abstract Article PDF–1.8M

Select item 74158996.

Signaling Between TRPV1/TRPV4 and Intracellular Hydrostatic Pressure in the Mouse Lens

Nicholas A. Delamere, Mohammad Shahidullah, Richard T. Mathias, Junyuan Gao, Xiuron Sun, Caterina Sellitto, Thomas W. White

Invest Ophthalmol Vis Sci. 2020 Jun; 61(6): 58. Published online 2020 Jun 29. doi: 10.1167/iovs.61.6.58

PMCID:: PMC7415899

Abstract Article PDF–1.4M

Select item 74014287.

Connexin 50-R205G Mutation Perturbs Lens Epithelial Cell Proliferation and Differentiation

Nikki Tjahjono, Chun-hong Xia, Rachel Li, Sarah Chu, Jessica Wang, Xiaohua Gong

Invest Ophthalmol Vis Sci. 2020 Mar; 61(3): 25. Published online 2020 Mar 17. doi: 10.1167/iovs.61.3.25

PMCID:: PMC7401428

Abstract Article PDF–15M

Select item 70902718.

p62/Sequestosome 1 levels increase and phosphorylation is altered in Cx50D47A lenses, but deletion of p62/sequestosome 1 does not improve transparency

Oscar Jara, Hubert Mysliwiec, Peter J. Minogue, Viviana M. Berthoud, Eric C. Beyer

Mol Vis. 2020; 26: 204–215. Published online 2020 Mar 18.

PMCID:: PMC7090271

Abstract Article PDF–4.3M

Select item 69256669.

CHOP is dispensable for lens transparency in wild-type and connexin50 mutant mice

Peter J. Minogue, Eric C. Beyer, Viviana M. Berthoud

Mol Vis. 2019; 25: 535–545. Published online 2019 Oct 3.

PMCID:: PMC6925666

Abstract Article PDF–1.6M

Select item 687628210.

Mutation in the mouse histone gene Hist2h3c1 leads to degeneration of the lens vesicle and severe microphthalmia

Sharmilee Vetrivel, Natascia Tiso, Andrea Kügler, Martin Irmler, Marion Horsch, Johannes Beckers, Daniela Hladik, Florian Giesert, Valerie Gailus-Durner, Helmut Fuchs, Sibylle Sabrautzki, Martin Hrabě de Angelis, Jochen Graw

Exp Eye Res. 2019 Nov; 188: 107632. doi: 10.1016/j.exer.2019.03.024

PMCID:: PMC6876282

Abstract Article

Select item 673634511.

Calcium-Activated Chloride Channels in Newly Differentiating Mouse Lens Fiber Cells and Their Role in Volume Regulation

Jun-Jie Tong, Pooja Acharya, Lisa Ebihara

Invest Ophthalmol Vis Sci. 2019 Apr; 60(5): 1621–1629. doi: 10.1167/iovs.19-26626

PMCID:: PMC6736345

Abstract Article PDF–970K

Select item 657042312.

Ankyrin-G regulated epithelial phenotype is required for mouse lens morphogenesis and growth

Pratheepa Kumari Rasiah, Rupalatha Maddala, Vann Bennett, Ponugoti Vasantha Rao

Dev Biol. Author manuscript; available in PMC 2020 Feb 1.

Published in final edited form as: Dev Biol. 2019 Feb 1; 446(1): 119–131. Published online 2018 Dec 15. doi: 10.1016/j.ydbio.2018.12.016

PMCID:: PMC6570423

Abstract Article PDF–1.5M

Select item 653401413.

The Connexin50D47A Mutant Causes Cataracts by Calcium Precipitation

Viviana M. Berthoud, Junyuan Gao, Peter J. Minogue, Oscar Jara, Richard T. Mathias, Eric C. Beyer

Invest Ophthalmol Vis Sci. 2019 May; 60(6): 2336–2346. doi: 10.1167/iovs.18-26459

PMCID:: PMC6534014

Abstract Article PDF–1.5M

Select item 616718914.

Chemical chaperone treatment improves levels and distributions of connexins in Cx50D47A mouse lenses

Oscar Jara, Peter J. Minogue, Viviana M. Berthoud, Eric C. Beyer

Exp Eye Res. Author manuscript; available in PMC 2019 Oct 1.

Published in final edited form as: Exp Eye Res. 2018 Oct; 175: 192–198. Published online 2018 Jun 18. doi: 10.1016/j.exer.2018.06.015

PMCID:: PMC6167189

Abstract Article PDF–831K

Select item 570116115.

Induction of Immune Surveillance of the Dysmorphogenic Lens

Caitlin M. Logan, Caitlin J. Bowen, A. Sue Menko

Sci Rep. 2017; 7: 16235. Published online 2017 Nov 24. doi: 10.1038/s41598-017-16456-5

PMCID:: PMC5701161

Abstract Article PDF–3.7M

Select item 552445916.

N-cadherin regulates signaling mechanisms required for lens fiber cell elongation and lens morphogenesis

Caitlin M. Logan, Suren Rajakaruna, Caitlin Bowen, Glenn L. Radice, Michael L. Robinson, A. Sue Menko

Dev Biol. Author manuscript; available in PMC 2018 Aug 1.

Published in final edited form as: Dev Biol. 2017 Aug 1; 428(1): 118–134. Published online 2017 May 26. doi: 10.1016/j.ydbio.2017.05.022

PMCID:: PMC5524459

Abstract Article PDF–3.4M

Select item 529582117.

High-throughput discovery of novel developmental phenotypes

Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray

Nature. Author manuscript; available in PMC 2017 Mar 14.

Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356