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Select item 107001381.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 106295572.

Regulation of replication origin licensing by ORC phosphorylation reveals a two-step mechanism for Mcm2-7 ring closing

Audra L. Amasino, Shalini Gupta, Larry J. Friedman, Jeff Gelles, Stephen P. Bell

Proc Natl Acad Sci U S A. 2023 Jul 18; 120(29): e2221484120. Published online 2023 Jul 10. doi: 10.1073/pnas.2221484120

PMCID:: PMC10629557

Abstract Article PDF–2.3M

Select item 98133923.

An essential Noc3p dimerization cycle mediates ORC double-hexamer formation in replication licensing

Aftab Amin, Rentian Wu, Muhammad Ajmal Khan, Man Hei Cheung, Yanting Liang, Changdong Liu, Guang Zhu, Zhi-Ling Yu, Chun Liang

Life Sci Alliance. 2023 Mar; 6(3): e202201594. Published online 2023 Jan 4. doi: 10.26508/lsa.202201594

PMCID:: PMC9813392

Abstract Article PDF–4.3M

Select item 92860234.

Mediator recruits the cohesin loader Scc2 to RNA Pol II-transcribed genes and promotes sister chromatid cohesion

Mark Mattingly, Chris Seidel, Sofía Muñoz, Yan Hao, Ying Zhang, Zhihui Wen, Laurence Florens, Frank Uhlmann, Jennifer L. Gerton

Curr Biol. 2022 Jul 11; 32(13): 2884–2896.e6. doi: 10.1016/j.cub.2022.05.019

PMCID:: PMC9286023

Abstract Article

Select item 92098115.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 88816116.

A mechanism of origin licensing control through autoinhibition of S. cerevisiae ORC·DNA·Cdc6

Jan Marten Schmidt, Ran Yang, Ashish Kumar, Olivia Hunker, Jan Seebacher, Franziska Bleichert

Nat Commun. 2022; 13: 1059. Published online 2022 Feb 25. doi: 10.1038/s41467-022-28695-w

PMCID:: PMC8881611

Abstract Article PDF–4.5M

Select item 85710637.

Systems-level effects of allosteric perturbations to a model molecular switch

Tina Perica, Christopher J. P. Mathy, Jiewei Xu, Gwendolyn M. Jang, Yang Zhang, Robyn Kaake, Noah Ollikainen, Hannes Braberg, Danielle L. Swaney, David G. Lambright, Mark J. S. Kelly, Nevan J. Krogan, Tanja Kortemme

Nature. Author manuscript; available in PMC 2022 May 1.

Published in final edited form as: Nature. 2021 Nov; 599(7883): 152–157. Published online 2021 Oct 13. doi: 10.1038/s41586-021-03982-6

PMCID:: PMC8571063

Abstract Article PDF–2.7M

Select item 74429558.

Biochemical and functional characterization of a meiosis-specific Pch2/ORC AAA+ assembly

María Ascensión Villar-Fernández, Richard Cardoso da Silva, Magdalena Firlej, Dongqing Pan, Elisabeth Weir, Annika Sarembe, Vivek B Raina, Tanja Bange, John R Weir, Gerben Vader

Life Sci Alliance. 2020 Nov; 3(11): e201900630. Published online 2020 Aug 21. doi: 10.26508/lsa.201900630

PMCID:: PMC7442955

Abstract Article PDF–3.2M

Select item 73864339.

Dosage suppression genetic interaction networks enhance functional wiring diagrams of the cell

Leslie Magtanong, Cheuk Hei Ho, Sarah L Barker, Wei Jiao, Anastasia Baryshnikova, Sondra Bahr, Andrew M Smith, Lawrence E Heisler, John S Choy, Elena Kuzmin, Kerry Andrusiak, Anna Kobylianski, Zhijian Li, Michael Costanzo, Munira A Basrai, Guri Giaever, Corey Nislow, Brenda Andrewa, Charles Boone

Nat Biotechnol. Author manuscript; available in PMC 2020 Jul 28.

Published in final edited form as: Nat Biotechnol. 2011 May 15; 29(6): 505–511. Published online 2011 May 15. doi: 10.1038/nbt.1855

PMCID:: PMC7386433

Abstract Article PDF–1.0M

Select item 727317710.

Chaperone-Mediated Protein Disaggregation Triggers Proteolytic Clearance of Intra-nuclear Protein Inclusions

Fabian den Brave, Lucas V. Cairo, Chandhuru Jagadeesan, Carmen Ruger-Herreros, Axel Mogk, Bernd Bukau, Stefan Jentsch

Cell Rep. 2020 Jun 2; 31(9): 107680. Published online 2020 Jun 2. doi: 10.1016/j.celrep.2020.107680

PMCID:: PMC7273177

Abstract Article

Select item 661571011.

The nucleotide sequence of Saccharomyces cerevisiae chromosome XII

M. Johnston, L. Hillier, L. Riles, other members of the Genome Sequencing Center, K. Albermann, B. André, W. Ansorge, V. Benes, M. Brückner, H. Delius, E. Dubois, A. Düsterhöft, K.-D. Entian, M. Floeth, A. Goffeau, U. Hebling, K. Heumann, D. Heuss-Neitzel, H. Hilbert, F. Hilger, K. Kleine, P. Kötter, E. J. Louis, F. Messenguy, H. W. Mewes, T. Miosga, D. Möstl, S. Müller-Auer, U. Nentwich, B. Obermaier, E. Piravandi, T. M. Pohl, D. Portetelle, B. Purnelle, S. Rechmann, M. Rieger, M. Rinke, M. Rose, M. Scharfe, B. Scherens, P. Scholler, C. Schwager, S. Schwarz, A. P. Underwood, L. A. Urrestarazu, M. Vandenbol, P. Verhasselt, F. Vierendeels, M Voet, G. Volckaert, H. Voss, R. Wambutt, E. Wedler, H. Wedler, F. K. Zimmermann, A. Zollner, J. Hani, J. D. Hoheisel

Nature. Author manuscript; available in PMC 2019 Jul 9.

Published in final edited form as: Nature. 1997 May 29; 387(6632 Suppl): 87–90.

PMCID:: PMC6615710

Abstract Article PDF–424K

Select item 621571312.

Systematic Analysis of Complex Genetic Interactions

Elena Kuzmin, Benjamin VanderSluis, Wen Wang, Guihong Tan, Raamesh Deshpande, Yiqun Chen, Matej Usaj, Attila Balint, Mojca Mattiazzi Usaj, Jolanda van Leeuwen, Elizabeth N. Koch, Carles Pons, Andrius J. Dagilis, Michael Pryszlak, Jason Zi Yang Wang, Julia Hanchard, Margot Riggi, Kaicong Xu, Hamed Heydari, Bryan-Joseph San Luis, Ermira Shuteriqi, Hongwei Zhu, Nydia Van Dyk, Sara Sharifpoor, Michael Costanzo, Robbie Loewith, Amy Caudy, Daniel Bolnick, Grant W. Brown, Brenda J. Andrews, Charles Boone, Chad L. Myers

Science. Author manuscript; available in PMC 2018 Nov 4.

Published in final edited form as: Science. 2018 Apr 20; 360(6386): eaao1729. doi: 10.1126/science.aao1729

PMCID:: PMC6215713

Abstract Article PDF–1.9M

Select item 580540913.

Multiple kinases inhibit origin licensing and helicase activation to ensure reductive cell division during meiosis

David V Phizicky, Luke E Berchowitz, Stephen P Bell

eLife. 2018; 7: e33309. Published online 2018 Feb 1. doi: 10.7554/eLife.33309

PMCID:: PMC5805409

Abstract Article PDF–3.1M

Select item 576535914.

Genome-Wide Mapping of Decay Factor–mRNA Interactions in Yeast Identifies Nutrient-Responsive Transcripts as Targets of the Deadenylase Ccr4

Jason E. Miller, Liye Zhang, Haoyang Jiang, Yunfei Li, B. Franklin Pugh, Joseph C. Reese

G3 (Bethesda) 2018 Jan; 8(1): 315–330. Published online 2017 Nov 20. doi: 10.1534/g3.117.300415

PMCID:: PMC5765359

Abstract Article PDF–2.2M

Select item 568948015.

Exploring Quantitative Yeast Phenomics with Single Cell Analysis of DNA Damage Foci

Erin B. Styles, Karen J. Founk, Lee A. Zamparo, Tina L. Sing, Dogus Altintas, Cyril Ribeyre, Virginie Ribaud, Jacques Rougemont, David Mayhew, Michael Costanzo, Matej Usaj, Adrian J. Verster, Elizabeth N. Koch, Daniele Novarina, Marco Graf, Brian Luke, Marco Muzi-Falconi, Chad L. Myers, Robi David Mitra, David Shore, Grant W. Brown, Zhaolei Zhang, Charles Boone, Brenda J. Andrews

Cell Syst. Author manuscript; available in PMC 2017 Nov 16.

Published in final edited form as: Cell Syst. 2016 Sep 28; 3(3): 264–277.e10. Published online 2016 Sep 8. doi: 10.1016/j.cels.2016.08.008

PMCID:: PMC5689480

Abstract Article PDF–2.9M

Select item 566188516.

A global interaction network maps a wiring diagram of cellular function

Michael Costanzo, Benjamin VanderSluis, Elizabeth N. Koch, Anastasia Baryshnikova, Carles Pons, Guihong Tan, Wen Wang, Matej Usaj, Julia Hanchard, Susan D. Lee, Vicent Pelechano, Erin B. Styles, Maximilian Billmann, Jolanda van Leeuwen, Nydia van Dyk, Zhen-Yuan Lin, Elena Kuzmin, Justin Nelson, Jeff S. Piotrowski, Tharan Srikumar, Sondra Bahr, Yiqun Chen, Raamesh Deshpande, Christoph F. Kurat, Sheena C. Li, Zhijian Li, Mojca Mattiazzi Usaj, Hiroki Okada, Natasha Pascoe, Bryan-Joseph San Luis, Sara Sharifpoor, Emira Shuteriqi, Scott W. Simpkins, Jamie Snider, Harsha Garadi Suresh, Yizhao Tan, Hongwei Zhu, Noel Malod-Dognin, Vuk Janjic, Natasa Przulj, Olga G. Troyanskaya, Igor Stagljar, Tian Xia, Yoshikazu Ohya, Anne-Claude Gingras, Brian Raught, Michael Boutros, Lars M. Steinmetz, Claire L. Moore, Adam P. Rosebrock, Amy A. Caudy, Chad L. Myers, Brenda Andrews, Charles Boone

Science. Author manuscript; available in PMC 2017 Oct 30.

Published in final edited form as: Science. 2016 Sep 23; 353(6306): aaf1420. doi: 10.1126/science.aaf1420

PMCID:: PMC5661885

Abstract Article PDF–2.6M

Select item 564803217.

Architecture and dynamics of overlapped RNA regulatory networks

Christopher P. Lapointe, Melanie A. Preston, Daniel Wilinski, Harriet A.J. Saunders, Zachary T. Campbell, Marvin Wickens

RNA. 2017 Nov; 23(11): 1636–1647. doi: 10.1261/rna.062687.117

PMCID:: PMC5648032

Abstract Article PDF–6.6M

Select item 560025418.

The Genetic Landscape of a Cell

Michael Costanzo, Anastasia Baryshnikova, Jeremy Bellay, Yungil Kim, Eric D. Spear, Carolyn S. Sevier, Huiming Ding, Judice L.Y. Koh, Kiana Toufighi, Sara Mostafavi, Jeany Prinz, Robert P. St. Onge, Benjamin VanderSluis, Taras Makhnevych, Franco J. Vizeacoumar, Solmaz Alizadeh, Sondra Bahr, Renee L. Brost, Yiqun Chen, Murat Cokol, Raamesh Deshpande, Zhijian Li, Zhen-Yuan Lin, Wendy Liang, Michaela Marback, Jadine Paw, Bryan-Joseph San Luis, Ermira Shuteriqi, Amy Hin Yan Tong, Nydia van Dyk, Iain M. Wallace, Joseph A. Whitney, Matthew T. Weirauch, Guoqing Zhong, Hongwei Zhu, Walid A. Houry, Michael Brudno, Sasan Ragibizadeh, Balázs Papp, Csaba Pál, Frederick P. Roth, Guri Giaever, Corey Nislow, Olga G. Troyanskaya, Howard Bussey, Gary D. Bader, Anne-Claude Gingras, Quaid D. Morris, Philip M. Kim, Chris A. Kaiser, Chad L. Myers, Brenda J. Andrews, Charles Boone

Science. Author manuscript; available in PMC 2017 Sep 15.

Published in final edited form as: Science. 2010 Jan 22; 327(5964): 425–431. doi: 10.1126/science.1180823

PMCID:: PMC5600254

Abstract Article PDF–2.4M

Select item 550350519.

Structural basis of MCM2-7 replicative helicase loading by ORC-Cdc6 and Cdt1

Zuanning Yuan, Alberto Riera, Lin Bai, Jingchuan Sun, Saikat Nandi, Christos Spanos, Zhuo Angel Chen, Marta Barbon, Juri Rappsilber, Bruce Stillman, Christian Speck, Huilin Li

Nat Struct Mol Biol. Author manuscript; available in PMC 2017 Aug 13.

Published in final edited form as: Nat Struct Mol Biol. 2017 Mar; 24(3): 316–324. Published online 2017 Feb 13. doi: 10.1038/nsmb.3372

PMCID:: PMC5503505

Abstract Article PDF–1.6M

Select item 501238420.

Histone Deacetylases with Antagonistic Roles in Saccharomyces cerevisiae Heterochromatin Formation

Deborah M. Thurtle-Schmidt, Anne E. Dodson, Jasper Rine

Genetics. 2016 Sep; 204(1): 177–190. Published online 2016 Aug 1. doi: 10.1534/genetics.116.190835

PMCID:: PMC5012384

Abstract Article PDF–6.4M

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