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Select item 108724771.

Protein interaction network revealed by quantitative proteomic analysis links TFIIB to multiple aspects of the transcription cycle

Michael J. O’Brien, Athar Ansari

Biochim Biophys Acta Proteins Proteom. Author manuscript; available in PMC 2024 Feb 16.

Published in final edited form as: Biochim Biophys Acta Proteins Proteom. 2024 Jan 1; 1872(1): 140968. Published online 2023 Oct 19. doi: 10.1016/j.bbapap.2023.140968

PMCID:: PMC10872477

Abstract Article PDF–1.7M

Select item 102333682.

A systematic proximity ligation approach to studying protein‐substrate specificity identifies the substrate spectrum of the Ssh1 translocon

Nir Cohen, Naama Aviram, Maya Schuldiner

EMBO J. 2023 Jun; 42(11): e113385. Published online 2023 Apr 19. doi: 10.15252/embj.2022113385

PMCID:: PMC10233368

Abstract Article PDF–1.2M

Select item 93392933.

Complex mutation profiles in mismatch repair and ribonucleotide reductase mutants reveal novel repair substrate specificity of MutS homolog (MSH) complexes

Natalie A Lamb, Jonathan E Bard, Raphael Loll-Krippleber, Grant W Brown, Jennifer A Surtees

Genetics. 2022 Aug; 221(4): iyac092. Published online 2022 Jun 10. doi: 10.1093/genetics/iyac092

PMCID:: PMC9339293

Abstract Article PDF–7.9M

Select item 92098114.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 89346515.

Yeast Ssd1 is a non-enzymatic member of the RNase II family with an alternative RNA recognition site

Rosemary A Bayne, Uma Jayachandran, Aleksandra Kasprowicz, Stefan Bresson, David Tollervey, Edward W J Wallace, Atlanta G Cook

Nucleic Acids Res. 2022 Mar 21; 50(5): 2923–2937. Published online 2021 Jul 24. doi: 10.1093/nar/gkab615

PMCID:: PMC8934651

Abstract Article PDF–4.4M

Select item 88816116.

A mechanism of origin licensing control through autoinhibition of S. cerevisiae ORC·DNA·Cdc6

Jan Marten Schmidt, Ran Yang, Ashish Kumar, Olivia Hunker, Jan Seebacher, Franziska Bleichert

Nat Commun. 2022; 13: 1059. Published online 2022 Feb 25. doi: 10.1038/s41467-022-28695-w

PMCID:: PMC8881611

Abstract Article PDF–4.5M

Select item 88567307.

Eco1-dependent cohesin acetylation anchors chromatin loops and cohesion to define functional meiotic chromosome domains

Rachael E Barton, Lucia F Massari, Daniel Robertson, Adèle L Marston

eLife. 2022; 11: e74447. Published online 2022 Feb 1. doi: 10.7554/eLife.74447

PMCID:: PMC8856730

Abstract Article PDF–16M

Select item 88308868.

Cdc6 is sequentially regulated by PP2A-Cdc55, Cdc14, and Sic1 for origin licensing in S. cerevisiae

Jasmin Philip, Mihkel Örd, Andriele Silva, Shaneen Singh, John FX Diffley, Dirk Remus, Mart Loog, Amy E Ikui

eLife. 2022; 11: e74437. Published online 2022 Feb 10. doi: 10.7554/eLife.74437

PMCID:: PMC8830886

Abstract Article PDF–2.5M

Select item 82223579.

The structure of ORC–Cdc6 on an origin DNA reveals the mechanism of ORC activation by the replication initiator Cdc6

Xiang Feng, Yasunori Noguchi, Marta Barbon, Bruce Stillman, Christian Speck, Huilin Li

Nat Commun. 2021; 12: 3883. Published online 2021 Jun 23. doi: 10.1038/s41467-021-24199-1

PMCID:: PMC8222357

Abstract Article PDF–4.9M

Select item 799803010.

DNA replication origins retain mobile licensing proteins

Humberto Sánchez, Kaley McCluskey, Theo van Laar, Edo van Veen, Filip M. Asscher, Belén Solano, John F. X. Diffley, Nynke H. Dekker

Nat Commun. 2021; 12: 1908. Published online 2021 Mar 26. doi: 10.1038/s41467-021-22216-x

PMCID:: PMC7998030

Abstract Article PDF–3.4M

Select item 771875111.

Comprehensive Synthetic Genetic Array Analysis of Alleles That Interact with Mutation of the Saccharomyces cerevisiae RecQ Helicases Hrq1 and Sgs1

Elsbeth Sanders, Phoebe A. Nguyen, Cody M. Rogers, Matthew L. Bochman

G3 (Bethesda) 2020 Dec; 10(12): 4359–4368. Published online 2020 Oct 28. doi: 10.1534/g3.120.401709

PMCID:: PMC7718751

Abstract Article PDF–1.2M

Select item 756090212.

Evolution of DNA replication origin specification and gene silencing mechanisms

Y. Hu, A. Tareen, Y-J. Sheu, W. T. Ireland, C. Speck, H. Li, L. Joshua-Tor, J. B. Kinney, B. Stillman

Nat Commun. 2020; 11: 5175. Published online 2020 Oct 14. doi: 10.1038/s41467-020-18964-x

PMCID:: PMC7560902

Abstract Article PDF–2.4M

Select item 739546013.

Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6

Zuanning Yuan, Sarah Schneider, Thomas Dodd, Alberto Riera, Lin Bai, Chunli Yan, Indiana Magdalou, Ivaylo Ivanov, Bruce Stillman, Huilin Li, Christian Speck

Proc Natl Acad Sci U S A. 2020 Jul 28; 117(30): 17747–17756. Published online 2020 Jul 15. doi: 10.1073/pnas.2006231117

Correction in:: Proc Natl Acad Sci U S A. 2021 Feb 9; 118(6): e2025413118.

PMCID:: PMC7395460

Abstract Article PDF–3.4M

Select item 732202214.

Sir2 mitigates an intrinsic imbalance in origin licensing efficiency between early- and late-replicating euchromatin

Timothy Hoggard, Carolin A. Müller, Conrad A. Nieduszynski, Michael Weinreich, Catherine A. Fox

Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14314–14321. Published online 2020 Jun 8. doi: 10.1073/pnas.2004664117

PMCID:: PMC7322022

Abstract Article PDF–5.3M

Select item 664889515.

Tsr4 and Nap1, two novel members of the ribosomal protein chaperOME

Ingrid Rössler, Julia Embacher, Benjamin Pillet, Guillaume Murat, Laura Liesinger, Jutta Hafner, Julia Judith Unterluggauer, Ruth Birner-Gruenberger, Dieter Kressler, Brigitte Pertschy

Nucleic Acids Res. 2019 Jul 26; 47(13): 6984–7002. Published online 2019 May 7. doi: 10.1093/nar/gkz317

PMCID:: PMC6648895

Abstract Article PDF–14M

Select item 662003416.

Cyclin-Specific Docking Mechanisms Reveal the Complexity of M-CDK Function in the Cell Cycle

Mihkel Örd, Rainis Venta, Kaidi Möll, Ervin Valk, Mart Loog

Mol Cell. 2019 Jul 11; 75(1): 76–89.e3. doi: 10.1016/j.molcel.2019.04.026

PMCID:: PMC6620034

Abstract Article

Select item 653292917.

Sir2 suppresses transcription-mediated displacement of Mcm2-7 replicative helicases at the ribosomal DNA repeats

Eric J. Foss, Tonibelle Gatbonton-Schwager, Adam H. Thiesen, Erin Taylor, Rafael Soriano, Uyen Lao, David M. MacAlpine, Antonio Bedalov

PLoS Genet. 2019 May; 15(5): e1008138. Published online 2019 May 13. doi: 10.1371/journal.pgen.1008138

PMCID:: PMC6532929

Abstract Article PDF–2.5M

Select item 653264718.

Transcriptional repression of CDC6 and SLD2 during meiosis is associated with production of short heterogeneous RNA isoforms

David V. Phizicky, Stephen P. Bell

Chromosoma. Author manuscript; available in PMC 2019 Dec 1.

Published in final edited form as: Chromosoma. 2018 Dec; 127(4): 515–527. Published online 2018 Oct 1. doi: 10.1007/s00412-018-0681-x

PMCID:: PMC6532647

Abstract Article PDF–1.7M

Select item 644262819.

Point centromere activity requires an optimal level of centromeric noncoding RNA

Yick Hin Ling, Karen Wing Yee Yuen

Proc Natl Acad Sci U S A. 2019 Mar 26; 116(13): 6270–6279. Published online 2019 Mar 8. doi: 10.1073/pnas.1821384116

PMCID:: PMC6442628

Abstract Article PDF–1.3M

Select item 599141620.

Yeast heterochromatin regulators Sir2 and Sir3 act directly at euchromatic DNA replication origins

Timothy A. Hoggard, FuJung Chang, Kelsey Rae Perry, Sandya Subramanian, Jessica Kenworthy, Julie Chueng, Erika Shor, Edel M. Hyland, Jef D. Boeke, Michael Weinreich, Catherine A. Fox

PLoS Genet. 2018 May; 14(5): e1007418. Published online 2018 May 24. doi: 10.1371/journal.pgen.1007418