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Select item 107001381.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 105509672.

Structure of the ceramide-bound SPOTS complex

Jan-Hannes Schäfer, Carolin Körner, Bianca M. Esch, Sergej Limar, Kristian Parey, Stefan Walter, Dovile Januliene, Arne Moeller, Florian Fröhlich

Nat Commun. 2023; 14: 6196. Published online 2023 Oct 4. doi: 10.1038/s41467-023-41747-z

PMCID:: PMC10550967

Abstract Article PDF–11M

Select item 102977003.

The Hsp90 molecular chaperone governs client proteins by targeting intrinsically disordered regions

Janhavi A. Kolhe, Neethu L. Babu, Brian C. Freeman

Mol Cell. Author manuscript; available in PMC 2024 Jun 15.

Published in final edited form as: Mol Cell. 2023 Jun 15; 83(12): 2035–2044.e7. Published online 2023 Jun 8. doi: 10.1016/j.molcel.2023.05.021

PMCID:: PMC10297700

Abstract Article PDF–2.0M

Select item 99305284.

SWR1 chromatin remodeling complex prevents mitotic slippage during spindle position checkpoint arrest

Ayse Koca Caydasi, Anton Khmelinskii, Zoulfia Darieva, Bahtiyar Kurtulmus, Michael Knop, Gislene Pereira

Mol Biol Cell. 2023 Feb 1; 34(2): ar11. Published online 2023 Jan 13. doi: 10.1091/mbc.E20-03-0179

PMCID:: PMC9930528

Abstract Article PDF–8.4M

Select item 92098115.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 85126076.

Regulation of sphingolipid synthesis by the G1/S transcription factor Swi4

Gabriel S. Matos, Juliana B. Madeira, Caroline Mota Fernandes, Deveney Dasilva, Claudio A. Masuda, Maurizio Del Poeta, Monica Montero-Lomelí

Biochim Biophys Acta Mol Cell Biol Lipids. Author manuscript; available in PMC 2022 Sep 1.

Published in final edited form as: Biochim Biophys Acta Mol Cell Biol Lipids. 2021 Sep; 1866(9): 158983. Published online 2021 May 29. doi: 10.1016/j.bbalip.2021.158983

PMCID:: PMC8512607

Abstract Article PDF–2.1M

Select item 77187517.

Comprehensive Synthetic Genetic Array Analysis of Alleles That Interact with Mutation of the Saccharomyces cerevisiae RecQ Helicases Hrq1 and Sgs1

Elsbeth Sanders, Phoebe A. Nguyen, Cody M. Rogers, Matthew L. Bochman

G3 (Bethesda) 2020 Dec; 10(12): 4359–4368. Published online 2020 Oct 28. doi: 10.1534/g3.120.401709

PMCID:: PMC7718751

Abstract Article PDF–1.2M

Select item 76150018.

The chaperone-binding activity of the mitochondrial surface receptor Tom70 protects the cytosol against mitoprotein-induced stress

Sandra Backes, Yury S. Bykov, Tamara Flohr, Markus Räschle, Jialin Zhou, Svenja Lenhard, Lena Krämer, Timo Mühlhaus, Chen Bibi, Cosimo Jann, Justin D. Smith, Lars M. Steinmetz, Doron Rapaport, Zuzana Storchová, Maya Schuldiner, Felix Boos, Johannes M. Herrmann

Cell Rep. Author manuscript; available in PMC 2023 Aug 31.

Published in final edited form as: Cell Rep. 2021 Apr 6; 35(1): 108936. doi: 10.1016/j.celrep.2021.108936

PMCID:: PMC7615001

Abstract Article PDF–3.4M

Select item 71998519.

Noncanonical regulation of phosphatidylserine metabolism by a Sec14-like protein and a lipid kinase

Yaxi Wang, Peihua Yuan, Aby Grabon, Ashutosh Tripathi, Dongju Lee, Martin Rodriguez, Max Lönnfors, Michal Eisenberg-Bord, Zehua Wang, Sin Man Lam, Maya Schuldiner, Vytas A. Bankaitis

J Cell Biol. 2020 May 4; 219(5): e201907128. Published online 2020 Apr 17. doi: 10.1083/jcb.201907128

PMCID:: PMC7199851

Abstract Article PDF–6.7M

Select item 666992210.

Endosome and Golgi‐associated degradation (EGAD) of membrane proteins regulates sphingolipid metabolism

Oliver Schmidt, Yannick Weyer, Verena Baumann, Michael A Widerin, Sebastian Eising, Mihaela Angelova, Alexander Schleiffer, Leopold Kremser, Herbert Lindner, Matthias Peter, Florian Fröhlich, David Teis

EMBO J. 2019 Aug 1; 38(15): e101433. Published online 2019 May 27. doi: 10.15252/embj.2018101433

PMCID:: PMC6669922

Abstract Article PDF–2.8M

Select item 637348911.

The ORMs Interact with Transmembrane Domain 1 of Lcb1 and Regulate Serine Palmitoyltransferase Oligomerization, Activity and Localization

Gongshe Han, Sita D. Gupta, Kenneth Gable, Dagmar Bacikova, Nivedita Sengupta, Niranjanakumari Somashekarappa, Richard L. Proia, Jeffrey M. Harmon, Teresa M. Dunn

Biochim Biophys Acta Mol Cell Biol Lipids. Author manuscript; available in PMC 2020 Mar 1.

Published in final edited form as: Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Mar; 1864(3): 245–259. Published online 2018 Dec 6. doi: 10.1016/j.bbalip.2018.11.007

PMCID:: PMC6373489

Abstract Article PDF–1.7M

Select item 621571312.

Systematic Analysis of Complex Genetic Interactions

Elena Kuzmin, Benjamin VanderSluis, Wen Wang, Guihong Tan, Raamesh Deshpande, Yiqun Chen, Matej Usaj, Attila Balint, Mojca Mattiazzi Usaj, Jolanda van Leeuwen, Elizabeth N. Koch, Carles Pons, Andrius J. Dagilis, Michael Pryszlak, Jason Zi Yang Wang, Julia Hanchard, Margot Riggi, Kaicong Xu, Hamed Heydari, Bryan-Joseph San Luis, Ermira Shuteriqi, Hongwei Zhu, Nydia Van Dyk, Sara Sharifpoor, Michael Costanzo, Robbie Loewith, Amy Caudy, Daniel Bolnick, Grant W. Brown, Brenda J. Andrews, Charles Boone, Chad L. Myers

Science. Author manuscript; available in PMC 2018 Nov 4.

Published in final edited form as: Science. 2018 Apr 20; 360(6386): eaao1729. doi: 10.1126/science.aao1729

PMCID:: PMC6215713

Abstract Article PDF–1.9M

Select item 621091713.

Tsc3 regulates SPT amino acid choice in Saccharomyces cerevisiae by promoting alanine in the sphingolipid pathway

Jihui Ren, Essa M. Saied, Aaron Zhong, Justin Snider, Christian Ruiz, Christoph Arenz, Lina M. Obeid, Geoffrey D. Girnun, Yusuf A. Hannun

J Lipid Res. 2018 Nov; 59(11): 2126–2139. Published online 2018 Aug 28. doi: 10.1194/jlr.M088195

PMCID:: PMC6210917

Abstract Article PDF–1.6M

Select item 592252814.

Global analysis of genetic circuitry and adaptive mechanisms enabling resistance to the azole antifungal drugs

Harley O’Connor Mount, Nicole M. Revie, Robert T. Todd, Kaitlin Anstett, Cathy Collins, Michael Costanzo, Charles Boone, Nicole Robbins, Anna Selmecki, Leah E. Cowen

PLoS Genet. 2018 Apr; 14(4): e1007319. Published online 2018 Apr 27. doi: 10.1371/journal.pgen.1007319

PMCID:: PMC5922528

Abstract Article PDF–7.1M

Select item 566188515.

A global interaction network maps a wiring diagram of cellular function

Michael Costanzo, Benjamin VanderSluis, Elizabeth N. Koch, Anastasia Baryshnikova, Carles Pons, Guihong Tan, Wen Wang, Matej Usaj, Julia Hanchard, Susan D. Lee, Vicent Pelechano, Erin B. Styles, Maximilian Billmann, Jolanda van Leeuwen, Nydia van Dyk, Zhen-Yuan Lin, Elena Kuzmin, Justin Nelson, Jeff S. Piotrowski, Tharan Srikumar, Sondra Bahr, Yiqun Chen, Raamesh Deshpande, Christoph F. Kurat, Sheena C. Li, Zhijian Li, Mojca Mattiazzi Usaj, Hiroki Okada, Natasha Pascoe, Bryan-Joseph San Luis, Sara Sharifpoor, Emira Shuteriqi, Scott W. Simpkins, Jamie Snider, Harsha Garadi Suresh, Yizhao Tan, Hongwei Zhu, Noel Malod-Dognin, Vuk Janjic, Natasa Przulj, Olga G. Troyanskaya, Igor Stagljar, Tian Xia, Yoshikazu Ohya, Anne-Claude Gingras, Brian Raught, Michael Boutros, Lars M. Steinmetz, Claire L. Moore, Adam P. Rosebrock, Amy A. Caudy, Chad L. Myers, Brenda Andrews, Charles Boone

Science. Author manuscript; available in PMC 2017 Oct 30.

Published in final edited form as: Science. 2016 Sep 23; 353(6306): aaf1420. doi: 10.1126/science.aaf1420

PMCID:: PMC5661885

Abstract Article PDF–2.6M

Select item 486983516.

One library to make them all: Streamlining yeast library creation by a SWAp-Tag (SWAT) strategy

Ido Yofe, Uri Weill, Matthias Meurer, Silvia Chuartzman, Einat Zalckvar, Omer Goldman, Shifra Ben-Dor, Conny Schütze, Nils Wiedemann, Michael Knop, Anton Khmelinskii, Maya Schuldiner

Nat Methods. Author manuscript; available in PMC 2016 Sep 22.

Published in final edited form as: Nat Methods. 2016 Apr; 13(4): 371–378. Published online 2016 Feb 29. doi: 10.1038/nmeth.3795