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Items: 1 to 20 of 143

1.
Direct targets of MEF2C are enriched for genes associated with schizophrenia and cognitive function and are involved in neuron development and mitochondrial function
Deema Ali, Aodán Laighneach, Emma Corley, Saahithh Redddi Patlola, Rebecca Mahoney, Laurena Holleran, Declan P. McKernan, John P. Kelly, Aiden P. Corvin, Brian Hallahan, Colm McDonald, Gary Donohoe, Derek W. Morris
PLoS Genet. 2024 Sep; 20(9): e1011093. Published online 2024 Sep 11. doi: 10.1371/journal.pgen.1011093
PMCID:
PMC11419381
AbstractArticlePDF–2.3M
2.
Aberrant ecotropic viral integration site-1 (EVI-1) and myocyte enhancer factor 2 C gene (MEF2C) in adult acute myeloid leukemia are associated with adverse t (9:22) & 11q23 rearrangements
Nadia El Menshawy, Mohamed S. El-Ghonemy, Mohamed A. Ebrahim, Maryan Waheeb Fahmi, Maha Saif, May Denewer, Shaimaa El-Ashwah
Ann Hematol. 2024; 103(7): 2355–2364. Published online 2024 May 7. doi: 10.1007/s00277-024-05779-9
PMCID:
PMC11224084
AbstractArticlePDF–1.4M
3.
MEF2C and miR-194-5p: New Players in Triple Negative Breast Cancer Tumorigenesis
Sara Caetano, Ana Rita Garcia, Inês Figueira, Maria Alexandra Brito
Int J Mol Sci. 2023 Sep; 24(18): 14297. Published online 2023 Sep 19. doi: 10.3390/ijms241814297
PMCID:
PMC10531597
AbstractArticlePDF–2.9M
4.
ERK5 Cooperates With MEF2C to Regulate Nr4a1 Transcription in MA-10 and MLTC-1 Leydig Cells
Karine de Mattos, Félix-Olivier Dumas, Gabriel Henrique Campolina-Silva, Clémence Belleannée, Robert S Viger, Jacques J Tremblay
Endocrinology. 2023 Sep; 164(9): bqad120. Published online 2023 Aug 4. doi: 10.1210/endocr/bqad120
PMCID:
PMC10435423
AbstractArticle
5.
Large‐scale phosphomimetic screening identifies phospho‐modulated motif‐based protein interactions
Johanna Kliche, Dimitriya Hristoforova Garvanska, Leandro Simonetti, Dilip Badgujar, Doreen Dobritzsch, Jakob Nilsson, Norman E Davey, Ylva Ivarsson
Mol Syst Biol. 2023 Jul; 19(7): e11164. Published online 2023 May 23. doi: 10.15252/msb.202211164
PMCID:
PMC10333884
AbstractArticlePDF–5.0M
6.
Using brain cell-type-specific protein interactomes to interpret neurodevelopmental genetic signals in schizophrenia
Yu-Han H. Hsu, Greta Pintacuda, Ruize Liu, Eugeniu Nacu, April Kim, Kalliopi Tsafou, Natalie Petrossian, William Crotty, Jung Min Suh, Jackson Riseman, Jacqueline M. Martin, Julia C. Biagini, Daya Mena, Joshua K.T. Ching, Edyta Malolepsza, Taibo Li, Tarjinder Singh, Tian Ge, Shawn B. Egri, Benjamin Tanenbaum, Caroline R. Stanclift, Annie M. Apffel, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Stanley Global Asia Initiatives, Steven A. Carr, Monica Schenone, Jake Jaffe, Nadine Fornelos, Hailiang Huang, Kevin C. Eggan, Kasper Lage
iScience. 2023 May 19; 26(5): 106701. Published online 2023 Apr 18. doi: 10.1016/j.isci.2023.106701
PMCID:
PMC10189495
AbstractArticlePDF–5.3M
7.
Role of MEF2C in the Endothelial Cells Derived from Human Induced Pluripotent Stem Cells
Tao Li, Kelsey L Conroy, Amy M Kim, Julian Halmai, Kewa Gao, Emily Moreno, Aijun Wang, Anthony G Passerini, Jan A Nolta, Ping Zhou
Stem Cells. 2023 Apr; 41(4): 341–353. Published online 2023 Jan 14. doi: 10.1093/stmcls/sxad005
PMCID:
PMC10128960
AbstractArticlePDF–43M
8.
MEF2C ameliorates learning, memory, and molecular pathological changes in Alzheimer’s disease in vivo and in vitro : Neuroprotective effects of MEF2C
Jiamou Ren, Shuli Zhang, Xiaoling Wang, Yuxin Deng, Yi Zhao, Yan Xiao, Jian Liu, Liangzhao Chu, Xiaolan Qi
Acta Biochim Biophys Sin (Shanghai) 2022 Jan; 54(1): 77–90. Published online 2021 Dec 28. doi: 10.3724/abbs.2021012
PMCID:
PMC9909301
AbstractArticlePDF–12M
9.
Silencing of lncRNA KLF3‐AS1 represses cell growth in osteosarcoma via miR‐338‐3p/MEF2C axis
Chunfa Chen, Liang Liu
J Clin Lab Anal. 2022 Nov; 36(11): e24698. Published online 2022 Oct 17. doi: 10.1002/jcla.24698
PMCID:
PMC9701870
AbstractArticlePDF–2.5M
10.
Transcriptional and functional consequences of alterations to MEF2C and its topological organization in neuronal models
Kiana Mohajeri, Rachita Yadav, Eva D'haene, Philip M. Boone, Serkan Erdin, Dadi Gao, Mariana Moyses-Oliveira, Riya Bhavsar, Benjamin B. Currall, Kathryn O'Keefe, Nicholas D. Burt, Chelsea Lowther, Diane Lucente, Monica Salani, Mathew Larson, Claire Redin, Olga Dudchenko, Erez Lieberman Aiden, Björn Menten, Derek J.C. Tai, James F. Gusella, Sarah Vergult, Michael E. Talkowski
Am J Hum Genet. 2022 Nov 3; 109(11): 2049–2067. Published online 2022 Oct 24. doi: 10.1016/j.ajhg.2022.09.015
PMCID:
PMC9674968
AbstractArticlePDF–5.0M
11.
Integrative Bioinformatics Analysis Reveals That miR-524-5p/MEF2C Regulates Bone Metastasis in Prostate Cancer and Breast Cancer
QingHua Tian, YingYing Lu, BiCong Yan, ChunGen Wu
Comput Math Methods Med. 2022; 2022: 5211329. Published online 2022 Sep 10. doi: 10.1155/2022/5211329
PMCID:
PMC9482681
AbstractArticlePDF–3.8M
12.
Hypermethylation of tumor suppressor lncRNA MEF2C-AS1 frequently happened in patients at all stages of colorectal carcinogenesis
Sangni Qian, Shujuan Lin, Xin Xu, Hao Bai, Aibuta Yeerken, Xiaojiang Ying, Zhenjun Li, Xinglin Fei, Jinhua Yang, Mengling Tang, Jianbing Wang, Mingjuan Jin, Kun Chen
Clin Epigenetics. 2022; 14: 111. Published online 2022 Sep 5. doi: 10.1186/s13148-022-01328-1
PMCID:
PMC9446566
AbstractArticlePDF–2.9M
13.
MEF2s are key regulators of cognitive function and confer resilience to neurodegeneration
Scarlett J. Barker, Ravikiran M. Raju, Jun Wang, Jose Davila-Velderrain, Fatima Gunter-Rahman, Fatema Abdurrob, Noah E.P. Milman, Karim Abdelaal, L. Ashley Watson, Lei Yu, David A. Bennett, Manolis Kellis, Li-Huei Tsai
Sci Transl Med. Author manuscript; available in PMC 2022 Jul 6.
Published in final edited form as: Sci Transl Med. 2021 Nov 3; 13(618): eabd7695. Published online 2021 Nov 3. doi: 10.1126/scitranslmed.abd7695
PMCID:
PMC9258338
AbstractArticlePDF–2.3M
14.
Clinical findings from the landmark MEF2C‐related disorders natural history study
Jessica A. Cooley Coleman, Sara M. Sarasua, Hannah Warren Moore, Luigi Boccuto, Christopher W. Cowan, Steven A. Skinner, Jane M. DeLuca
Mol Genet Genomic Med. 2022 Jun; 10(6): e1919. Published online 2022 Apr 13. doi: 10.1002/mgg3.1919
PMCID:
PMC9184670
AbstractArticlePDF–2.3M
15.
Activin A Causes Muscle Atrophy through MEF2C-Dependent Impaired Myogenesis
Audrey Loumaye, Pascale Lause, Xiaoling Zhong, Teresa A. Zimmers, Laure B. Bindels, Jean-Paul Thissen
Cells. 2022 Apr; 11(7): 1119. Published online 2022 Mar 25. doi: 10.3390/cells11071119
PMCID:
PMC8997966
AbstractArticlePDF–2.0M
16.
Human transcription factor protein interaction networks
Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo
Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5
PMCID:
PMC8828895
AbstractArticlePDF–1.7M
17.
Progress on the roles of MEF2C in neuropsychiatric diseases
Zhikun Zhang, Yongxiang Zhao
Mol Brain. 2022; 15: 8. Published online 2022 Jan 6. doi: 10.1186/s13041-021-00892-6
PMCID:
PMC8740500
AbstractArticlePDF–953K
18.
Polymorphisms in Genes Involved in Osteoblast Differentiation and Function Are Associated with Anthropometric Phenotypes in Spanish Women
Clara Pertusa, Sofía P. Ruzo, Layla Panach, Damián Mifsut, Juan J. Tarín, Antonio Cano, Miguel Ángel García-Pérez
Genes (Basel) 2021 Dec; 12(12): 2012. Published online 2021 Dec 17. doi: 10.3390/genes12122012
PMCID:
PMC8701034
AbstractArticlePDF–2.2M
19.
MEF2C silencing downregulates NF2 and E-cadherin and enhances Erastin-induced ferroptosis in meningioma
Zhongyuan Bao, Lingyang Hua, Yangfan Ye, Daijun Wang, Chong Li, Qing Xie, Hiroaki Wakimoto, Ye Gong, Jing Ji
Neuro Oncol. 2021 Dec; 23(12): 2014–2027. Published online 2021 May 13. doi: 10.1093/neuonc/noab114
PMCID:
PMC8643460
AbstractArticlePDF–20M
20.
MicroRNA-190b expression predicts a good prognosis and attenuates the malignant progression of pancreatic cancer by targeting MEF2C and TCF4
Yunwei Li, Zhe Wang, Feng Zhao, Juan Zeng, Xianghong Yang
Oncol Rep. 2022 Jan; 47(1): 12. Published online 2021 Nov 10. doi: 10.3892/or.2021.8223
PMCID:
PMC8600408
AbstractArticlePDF–1.0M

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