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Select item 110377201.

Interferon γ (IFNγ) gene transfer of an EMT6 tumor that is poorly responsive to IFNγ stimulation: increase in tumor immunogenicity is accompanied by induction of a mouse class II transactivator and class II MHC

Monica C. Panelli, E. Wang, Shanxiang Shen, Samuel F. Schluter, Ralph M. Bernstein, Evan M. Hersh, Alison Stopeck, Ramarao Gangavalli, Jack Barber, Douglas Jolly, E. T. Akporiaye

Cancer Immunol Immunother. 1996 Mar; 42(2): 99–107. doi: 10.1007/s002620050258

PMCID:: PMC11037720

Abstract Article PDF–3.2M

Select item 101385882.

NLRC5-CIITA Fusion Protein as an Effective Inducer of MHC-I Expression and Antitumor Immunity

Madanraj Appiya Santharam, Akhil Shukla, Dominique Levesque, Thomas A. Kufer, François-Michel Boisvert, Sheela Ramanathan, Subburaj Ilangumaran

Int J Mol Sci. 2023 Apr; 24(8): 7206. Published online 2023 Apr 13. doi: 10.3390/ijms24087206

PMCID:: PMC10138588

Abstract Article PDF–2.8M

Select item 88604473.

Thymocytes trigger self-antigen-controlling pathways in immature medullary thymic epithelial stages

Noella Lopes, Nicolas Boucherit, Jérémy C Santamaria, Nathan Provin, Jonathan Charaix, Pierre Ferrier, Matthieu Giraud, Magali Irla

eLife. 2022; 11: e69982. Published online 2022 Feb 21. doi: 10.7554/eLife.69982

PMCID:: PMC8860447

Abstract Article PDF–4.1M

Select item 86713554.

Neoantigen driven B cell and CD4 T follicular helper cell collaboration promotes anti-tumor CD8 T cell responses

Can Cui, Jiawei Wang, Eric Fagerberg, Ping-Min Chen, Kelli A. Connolly, Martina Damo, Julie F. Cheung, Tianyang Mao, Adnan S. Askari, Shuting Chen, Brittany Fitzgerald, Gena G. Foster, Stephanie C. Eisenbarth, Hongyu Zhao, Joseph Craft, Nikhil S. Joshi

Cell. Author manuscript; available in PMC 2022 Dec 9.

Published in final edited form as: Cell. 2021 Dec 9; 184(25): 6101–6118.e13. Published online 2021 Nov 30. doi: 10.1016/j.cell.2021.11.007

PMCID:: PMC8671355

Abstract Article PDF–1.5M

Select item 82390235.

Type II alveolar cell MHCII improves respiratory viral disease outcomes while exhibiting limited antigen presentation

Sushila A. Toulmin, Chaitali Bhadiadra, Andrew J. Paris, Jeffrey H. Lin, Jeremy Katzen, Maria C. Basil, Edward E. Morrisey, G. Scott Worthen, Laurence C. Eisenlohr

Nat Commun. 2021; 12: 3993. Published online 2021 Jun 28. doi: 10.1038/s41467-021-23619-6

PMCID:: PMC8239023

Abstract Article PDF–2.5M

Select item 79387706.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 78648747.

Mechanism of EBV inducing anti-tumour immunity and its therapeutic use

Il-Kyu Choi, Zhe Wang, Qiang Ke, Min Hong, Dereck W. Paul, Jr, Stacey M. Fernandes, Zhuting Hu, Jonathan Stevens, Indira Guleria, Hye-Jung Kim, Harvey Cantor, Kai W. Wucherpfennig, Jennifer R. Brown, Jerome Ritz, Baochun Zhang

Nature. Author manuscript; available in PMC 2021 Jun 23.

Published in final edited form as: Nature. 2021 Feb; 590(7844): 157–162. Published online 2020 Dec 23. doi: 10.1038/s41586-020-03075-w

PMCID:: PMC7864874

Abstract Article PDF–3.7M

Select item 76658418.

MHC class II transactivator CIITA induces cell resistance to Ebola virus and SARS-like coronaviruses

Anna Bruchez, Ky Sha, Joshua Johnson, Li Chen, Caroline Stefani, Hannah McConnell, Lea Gaucherand, Rachel Prins, Kenneth A. Matreyek, Adam J. Hume, Elke Mühlberger, Emmett V. Schmidt, Gene G. Olinger, Lynda M. Stuart, Adam Lacy-Hulbert

Science. 2020 Oct 9; 370(6513): 241–247. Published online 2020 Aug 27. doi: 10.1126/science.abb3753

PMCID:: PMC7665841

Abstract Article PDF–1.5M

Select item 62978619.

Absence of MHC-II expression by lymph node stromal cells results in autoimmunity

Juan Dubrot, Fernanda V Duraes, Guillaume Harlé, Anjalie Schlaeppi, Dale Brighouse, Natacha Madelon, Christine Göpfert, Nadine Stokar-Regenscheit, Hans Acha-Orbea, Walter Reith, Monique Gannagé, Stephanie Hugues

Life Sci Alliance. 2018 Dec; 1(6): e201800164. Published online 2018 Dec 17. doi: 10.26508/lsa.201800164

PMCID:: PMC6297861

Abstract Article PDF–1.9M

Select item 621974010.

Macrophage-specific MHCII expression is regulated by a remote Ciita enhancer controlled by NFAT5

Maria Buxadé, Hector Huerga Encabo, Marta Riera-Borrull, Lucía Quintana-Gallardo, Pilar López-Cotarelo, Mónica Tellechea, Sara Martínez-Martínez, Juan Miguel Redondo, Juan Martín-Caballero, Juana María Flores, Elena Bosch, José Luis Rodríguez-Fernández, Jose Aramburu, Cristina López-Rodríguez

J Exp Med. 2018 Nov 5; 215(11): 2901–2918. doi: 10.1084/jem.20180314

PMCID:: PMC6219740

Abstract Article PDF–2.8M

Select item 611792711.

Targeting of the class II transactivator attenuates inflammation and neurodegeneration in an alpha-synuclein model of Parkinson’s disease

Gregory P. Williams, Aubrey M. Schonhoff, Asta Jurkuvenaite, Aaron D. Thome, David G. Standaert, Ashley S. Harms

J Neuroinflammation. 2018; 15: 244. Published online 2018 Aug 30. doi: 10.1186/s12974-018-1286-2

PMCID:: PMC6117927

Abstract Article PDF–8.3M

Select item 603339812.

B lymphocytes can be activated to act as antigen presenting cells to promote anti-tumor responses

Renata Ariza Marques Rossetti, Noely Paula Cristina Lorenzi, Kaori Yokochi, Maria Beatriz Sartor de Faria Rosa, Luciana Benevides, Paulo Francisco Ramos Margarido, Edmund Chada Baracat, Jesus Paula Carvalho, Luisa Lina Villa, Ana Paula Lepique

PLoS One. 2018; 13(7): e0199034. Published online 2018 Jul 5. doi: 10.1371/journal.pone.0199034

PMCID:: PMC6033398

Abstract Article PDF–3.0M

Select item 575783913.

Revisiting the specificity of the MHC class II transactivator CIITA in classical murine dendritic cells in vivo

David A. Anderson, III, Gary E. Grajales-Reyes, Ansuman T. Satpathy, Carlos E. Vasquez Hueichucura, Theresa L. Murphy, Kenneth M. Murphy

Eur J Immunol. Author manuscript; available in PMC 2018 Feb 1.

Published in final edited form as: Eur J Immunol. 2017 Aug; 47(8): 1317–1323. Published online 2017 Jul 14. doi: 10.1002/eji.201747050

PMCID:: PMC5757839

Abstract Article PDF–780K

Select item 539321714.

Deficiency of transcription factor RelB perturbs myeloid and DC development by hematopoietic-extrinsic mechanisms

Carlos G. Briseño, Marco Gargaro, Vivek Durai, Jesse T. Davidson, Derek J. Theisen, David A. Anderson, III, Deborah V. Novack, Theresa L. Murphy, Kenneth M. Murphy

Proc Natl Acad Sci U S A. 2017 Apr 11; 114(15): 3957–3962. Published online 2017 Mar 27. doi: 10.1073/pnas.1619863114

PMCID:: PMC5393217

Abstract Article PDF–1.4M

Select item 537172715.

The Spontaneous Autoimmune Neuromyopathy in ICOSL^−/− NOD Mice Is CD4⁺ T-Cell and Interferon-γ Dependent

Claire Briet, Gwladys Bourdenet, Ute C. Rogner, Chantal Becourt, Isabelle Tardivel, Laurent Drouot, Christophe Arnoult, Jean-Claude do Rego, Nicolas Prevot, Charbel Massaad, Olivier Boyer, Christian Boitard

Front Immunol. 2017; 8: 287. Published online 2017 Mar 31. doi: 10.3389/fimmu.2017.00287

PMCID:: PMC5371727

Abstract Article PDF–2.8M

Select item 534335516.

Effects of C2ta genetic polymorphisms on MHC class II expression and autoimmune diseases

Anthony C. Y. Yau, Fredrik Piehl, Tomas Olsson, Rikard Holmdahl

Immunology. 2017 Apr; 150(4): 408–417. Published online 2016 Dec 22. doi: 10.1111/imm.12692

PMCID:: PMC5343355

Abstract Article PDF–416K

Select item 519602617.

The Heterogeneity of Ly6C^hi Monocytes Controls Their Differentiation into iNOS⁺ Macrophages or Monocyte-Derived Dendritic Cells

Shinelle Menezes, Daisy Melandri, Giorgio Anselmi, Thibaut Perchet, Jakob Loschko, Juan Dubrot, Rajen Patel, Emmanuel L. Gautier, Stéphanie Hugues, M. Paula Longhi, Jake Y. Henry, Sergio A. Quezada, Grégoire Lauvau, Ana-Maria Lennon-Duménil, Enrique Gutiérrez-Martínez, Alain Bessis, Elisa Gomez-Perdiguero, Christian E. Jacome-Galarza, Hannah Garner, Frederic Geissmann, Rachel Golub, Michel C. Nussenzweig, Pierre Guermonprez

Immunity. 2016 Dec 20; 45(6): 1205–1218. doi: 10.1016/j.immuni.2016.12.001

PMCID:: PMC5196026

Abstract Article

Select item 488636318.

Bridging channel dendritic cells induce immunity to transfused red blood cells

Samuele Calabro, Antonia Gallman, Uthaman Gowthaman, Dong Liu, Pei Chen, Jingchun Liu, Jayendra Kumar Krishnaswamy, Manuela Sales L. Nascimento, Lan Xu, Seema R. Patel, Adam Williams, Christopher A. Tormey, Eldad A. Hod, Steven L. Spitalnik, James C. Zimring, Jeanne E. Hendrickson, Sean R. Stowell, Stephanie C. Eisenbarth

J Exp Med. 2016 May 30; 213(6): 887–896. doi: 10.1084/jem.20151720

PMCID:: PMC4886363

Abstract Article PDF–1.8M

Select item 487508919.

A novel CARD containing splice-isoform of CIITA regulates nitric oxide synthesis in dendritic cells

Dachuan Huang, Sylvia Lim, Rong Yuan Ray Chua, Hong Shi, Mah Lee Ng, Siew Heng Wong

Protein Cell. 2010 Mar; 1(3): 291–306. Published online 2010 Apr 17. doi: 10.1007/s13238-010-0039-5

PMCID:: PMC4875089

Abstract Article PDF–5.3M

Select item 472053620.

Interleukin-2-dependent allergen-specific tissue resident memory cells drive asthma

Brian D. Hondowicz, Dowon An, Jason M. Schenkel, Karen S. Kim, Holly R. Steach, Akshay T. Krishnamurty, Gladys J. Keitany, Esteban N. Garza, Kathryn A. Fraser, James J. Moon, William A. Altemeier, David Masopust, Marion Pepper

Immunity. Author manuscript; available in PMC 2017 Jan 19.

Published in final edited form as: Immunity. 2016 Jan 19; 44(1): 155–166. Published online 2015 Dec 29. doi: 10.1016/j.immuni.2015.11.004

PMCID:: PMC4720536

Abstract Article PDF–1.6M

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