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Items: 1 to 20 of 103

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Mice lacking cyclophilin B, but not cyclophilin A, are protected from the development of NASH in a diet and chemical-induced model
Winston T. Stauffer, Asha Z. Goodman, Michael Bobardt, Daren R. Ure, Robert T. Foster, Philippe Gallay
PLoS One. 2024; 19(3): e0298211. Published online 2024 Mar 1. doi: 10.1371/journal.pone.0298211
PMCID:
PMC10906846
AbstractArticlePDF–3.5M
3.
Hepatic ribosomal protein S6 (Rps6) insufficiency results in failed bile duct development and loss of hepatocyte viability; a ribosomopathy-like phenotype that is partially p53-dependent
Sarah A. Comerford, Elizabeth A. Hinnant, Yidong Chen, Robert E. Hammer
PLoS Genet. 2023 Jan; 19(1): e1010595. Published online 2023 Jan 19. doi: 10.1371/journal.pgen.1010595
PMCID:
PMC9888725
AbstractArticlePDF–6.9M
4.
The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3
Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany
Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527
PMCID:
PMC9603860
AbstractArticlePDF–3.4M
5.
ALS-linked loss of Cyclin-F function affects HSP90
Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends
Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359
PMCID:
PMC9481933
AbstractArticlePDF–3.5M
6.
APOE4 accelerates advanced-stage vascular and neurodegenerative disorder in old Alzheimer’s mice via cyclophilin A independently of amyloid-β
Axel Montagne, Angeliki M. Nikolakopoulou, Mikko T. Huuskonen, Abhay P. Sagare, Erica J. Lawson, Divna Lazic, Sanket V. Rege, Alexandra Grond, Edward Zuniga, Samuel R. Barnes, Jacob Prince, Meghana Sagare, Ching-Ju Hsu, Mary J. LaDu, Russell E. Jacobs, Berislav V. Zlokovic
Nat Aging. Author manuscript; available in PMC 2022 Mar 14.
Published in final edited form as: Nat Aging. 2021 Jun; 1(6): 506–520. Published online 2021 Jun 14. doi: 10.1038/s43587-021-00073-z
Correction in:
Nat Aging. 2021 Jul; 1(7): 624.
PMCID:
PMC8920485
AbstractArticlePDF–3.8M
7.
Intracellular immune sensing promotes inflammation via gasdermin D-driven release of a lectin alarmin
Ashley J. Russo, Swathy O. Vasudevan, Santiago P. Méndez-Huergo, Puja Kumari, Antoine Menoret, Shivalee Duduskar, Chengliang Wang, Juan M. Pérez Sáez, Margaret M. Fettis, Chuan Li, Renjie Liu, Arun Wanchoo, Karthik Chandiran, Jianbin Ruan, Sivapriya Kailasan Vanaja, Michael Bauer, Christoph Sponholz, Gregory A. Hudalla, Anthony T. Vella, Beiyan Zhou, Sachin D. Deshmukh, Gabriel A. Rabinovich, Vijay A. Rathinam
Nat Immunol. Author manuscript; available in PMC 2022 Mar 11.
Published in final edited form as: Nat Immunol. 2021 Feb; 22(2): 154–165. Published online 2021 Jan 4. doi: 10.1038/s41590-020-00844-7
PMCID:
PMC8916041
AbstractArticlePDF–3.8M
8.
Cyclophilin A Is Not Acetylated at Lysine-82 and Lysine-125 in Resting and Stimulated Platelets
Annabelle Rosa, Elke Butt, Christopher P. Hopper, Stefan Loroch, Markus Bender, Harald Schulze, Albert Sickmann, Sandra Vorlova, Peter Seizer, David Heinzmann, Alma Zernecke
Int J Mol Sci. 2022 Feb; 23(3): 1469. Published online 2022 Jan 27. doi: 10.3390/ijms23031469
PMCID:
PMC8836233
AbstractArticlePDF–2.1M
9.
Defective cyclophilin A induces TDP-43 proteinopathy: implications for amyotrophic lateral sclerosis and frontotemporal dementia
Laura Pasetto, Maurizio Grassano, Silvia Pozzi, Silvia Luotti, Eliana Sammali, Alice Migazzi, Manuela Basso, Giovanni Spagnolli, Emiliano Biasini, Edoardo Micotti, Milica Cerovic, Mirjana Carli, Gianluigi Forloni, Giovanni De Marco, Umberto Manera, Cristina Moglia, Gabriele Mora, Bryan J Traynor, Adriano Chiò, Andrea Calvo, Valentina Bonetto
Brain. 2021 Dec; 144(12): 3710–3726. Published online 2021 Dec 31. doi: 10.1093/brain/awab333
PMCID:
PMC8719849
AbstractArticlePDF–1.9M
10.
Cyclophilin A Impairs Efferocytosis and Accelerates Atherosclerosis by Overexpressing CD 47 and Down-Regulating Calreticulin
Vinitha Anandan, Thushara Thulaseedharan, Aishwarya Suresh Kumar, Karthika Chandran Latha, Amjesh Revikumar, Ajit Mullasari, Chandrasekharan C. Kartha, Abdul Jaleel, Surya Ramachandran
Cells. 2021 Dec; 10(12): 3598. Published online 2021 Dec 20. doi: 10.3390/cells10123598
PMCID:
PMC8700718
AbstractArticlePDF–5.0M
11.
Ppia is the most stable housekeeping gene for qRT-PCR normalization in kidneys of three Pkd1-deficient mouse models
Juan J. Muñoz, Ana C. Anauate, Andressa G. Amaral, Frederico M. Ferreira, Elieser H. Watanabe, Renata Meca, Milene S. Ormanji, Mirian A. Boim, Luiz F. Onuchic, Ita P. Heilberg
Sci Rep. 2021; 11: 19798. Published online 2021 Oct 5. doi: 10.1038/s41598-021-99366-x
PMCID:
PMC8492864
AbstractArticlePDF–2.4M
12.
Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins
Benjamin Lang, Jae-Seong Yang, Mireia Garriga-Canut, Silvia Speroni, Moritz Aschern, Maria Gili, Tobias Hoffmann, Gian Gaetano Tartaglia, Sebastian P Maurer
Nucleic Acids Res. 2021 Jul 9; 49(12): 6702–6721. Published online 2021 Jun 16. doi: 10.1093/nar/gkab490
PMCID:
PMC8266617
AbstractArticlePDF–4.0M
13.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
14.
Inhibition of the Activity of Cyclophilin A Impedes Prolactin Receptor-Mediated Signaling, Mammary Tumorigenesis, and Metastases
Shawn Hakim, Justin M. Craig, Jennifer E. Koblinski, Charles V. Clevenger
iScience. 2020 Oct 23; 23(10): 101581. Published online 2020 Sep 19. doi: 10.1016/j.isci.2020.101581
PMCID:
PMC7549119
AbstractArticlePDF–4.0M
15.
Interleukin 37 (IL-37) Reduces High Glucose-Induced Inflammation, Oxidative Stress, and Apoptosis of Podocytes by Inhibiting the STAT3–Cyclophilin A (CypA) Signaling Pathway
Xiaobo Zhang, Ying Zhu, Ying Zhou, Bingru Fei
Med Sci Monit. 2020; 26: e922979-1–e922979-11. Prepublished online 2020 Jul 21. Published online 2020 Sep 15. doi: 10.12659/MSM.922979
PMCID:
PMC7518013
AbstractArticlePDF–1.3M
16.
Deficiency in the glycosyltransferase Gcnt1 increases susceptibility to tuberculosis through a mechanism involving neutrophils
Kaori L. Fonseca, Ana Raquel Maceiras, Rita Matos, Luisa Simoes-Costa, Jeremy Sousa, Baltazar Cá, Leandro Barros, Ana Isabel Fernandes, Stefan Mereiter, Ricardo Reis, Joana Gomes, Gustavo Tapia, Paula Rodríguez-Martínez, Montse Martín-Céspedes, Sergo Vashakidze, Shota Gogishvili, Keti Nikolaishvili, Rui Appelberg, Fátima Gärtner, Pedro N. S. Rodrigues, Cristina Vilaplana, Celso A. Reis, Ana Magalhães, Margarida Saraiva
Mucosal Immunol. 2020; 13(5): 836–848. Published online 2020 Mar 13. doi: 10.1038/s41385-020-0277-7
PMCID:
PMC7434595
AbstractArticlePDF–3.5M
17.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
AbstractArticlePDF–2.0M
18.
GCNT1-mediated O-glycosylation of the sialomucin CD43 is a sensitive indicator of Notch signaling in activated T cells
Eric Perkey, Dave Maurice De Sousa, Léolène Carrington, Jooho Chung, Alexander Dils, David Granadier, Ute Koch, Freddy Radtke, Burkhard Ludewig, Bruce R. Blazar, Christian W. Siebel, Todd V. Brennan, Jeffrey Nolz, Nathalie Labrecque, Ivan Maillard
J Immunol. Author manuscript; available in PMC 2020 Sep 15.
Published in final edited form as: J Immunol. 2020 Mar 15; 204(6): 1674–1688. Published online 2020 Feb 14. doi: 10.4049/jimmunol.1901194
PMCID:
PMC7306398
AbstractArticlePDF–1.3M
19.
Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant
Meagan A. Quinlan, Matthew J. Robson, Ran Ye, Kristie L. Rose, Kevin L. Schey, Randy D. Blakely
Front Mol Neurosci. 2020; 13: 89. Published online 2020 Jun 8. doi: 10.3389/fnmol.2020.00089
PMCID:
PMC7295033
AbstractArticlePDF–2.7M
20.
Cyclophilin A Promotes Inflammation in Acute Kidney Injury but Not in Renal Fibrosis
Khai Gene Leong, Elyce Ozols, John Kanellis, David J. Nikolic-Paterson, Frank Y. Ma
Int J Mol Sci. 2020 May; 21(10): 3667. Published online 2020 May 22. doi: 10.3390/ijms21103667
PMCID:
PMC7279441
AbstractArticlePDF–14M

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