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Select item 116105221.

The BAF chromatin complex component SMARCC1 does not mediate GLI transcriptional repression of Hedgehog target genes in limb buds

Janani Ramachandran, Wanlu Chen, Rachel K. Lex, Kathryn E. Windsor, Hyunji Lee, Tingchang Wang, Weiqiang Zhou, Hongkai Ji, Steven A. Vokes

Dev Biol. Author manuscript; available in PMC 2024 Dec 2.

Published in final edited form as: Dev Biol. 2023 Dec; 504: 128–136. Published online 2023 Oct 5. doi: 10.1016/j.ydbio.2023.10.001

PMCID:: PMC11610522

Article PDF–1.7M

Select item 111409072.

Knockout mice with pituitary malformations help identify human cases of hypopituitarism

Julian Martinez-Mayer, Michelle L. Brinkmeier, Sean P. O’Connell, Arnold Ukagwu, Marcelo A. Marti, Mirta Miras, Maria V. Forclaz, Maria G. Benzrihen, Leonard Y. M. Cheung, Sally A. Camper, Buffy S. Ellsworth, Lori T. Raetzman, Maria I. Pérez-Millán, Shannon W. Davis

Genome Med. 2024; 16: 75. Published online 2024 May 31. doi: 10.1186/s13073-024-01347-y

PMCID:: PMC11140907

Article PDF–4.4M

Select item 111399273.

ARID1B maintains mesenchymal stem cell quiescence via inhibition of BCL11B-mediated non-canonical Activin signaling

Mingyi Zhang, Tingwei Guo, Fei Pei, Jifan Feng, Junjun Jing, Jian Xu, Takahiko Yamada, Thach-Vu Ho, Jiahui Du, Prerna Sehgal, Yang Chai

Nat Commun. 2024; 15: 4614. Published online 2024 May 30. doi: 10.1038/s41467-024-48285-2

PMCID:: PMC11139927

Article PDF–16M

Select item 110591894.

Life-long Restructuring of 3D Genome Architecture in Cerebellar Granule Cells

Longzhi Tan, Jenny Shi, Siavash Moghadami, Bibudha Parasar, Cydney P. Wright, Yunji Seo, Kristen Vallejo, Inma Cobos, Laramie Duncan, Ritchie Chen, Karl Deisseroth

Science. Author manuscript; available in PMC 2024 Apr 30.

Published in final edited form as: Science. 2023 Sep 8; 381(6662): 1112–1119. Published online 2023 Sep 7. doi: 10.1126/science.adh3253

PMCID:: PMC11059189

Article PDF–3.5M

Select item 109548045.

Genetic background determines synaptic phenotypes in Arid1b-mutant mice

Hyosang Kim, Eunjoon Kim

Front Psychiatry. 2023; 14: 1341348. Published online 2024 Mar 7. doi: 10.3389/fpsyt.2023.1341348

PMCID:: PMC10954804

Article PDF–1.5M

Select item 109421086.

Increased genomic instability and reshaping of tissue microenvironment underlie oncogenic properties of Arid1a mutations

Alessandro D’Ambrosio, Davide Bressan, Elisa Ferracci, Francesco Carbone, Patrizia Mulè, Federico Rossi, Caterina Barbieri, Elisa Sorrenti, Gaia Fiaccadori, Thomas Detone, Elena Vezzoli, Salvatore Bianchi, Chiara Sartori, Simona Corso, Akihisa Fukuda, Giovanni Bertalot, Andrea Falqui, Mattia Barbareschi, Alessandro Romanel, Diego Pasini, Fulvio Chiacchiera

Sci Adv. 2024 Mar 15; 10(11): eadh4435. Published online 2024 Mar 15. doi: 10.1126/sciadv.adh4435

PMCID:: PMC10942108

Article PDF–9.8M

Select item 109176607.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Article PDF–4.8M

Select item 109068468.

Mice lacking cyclophilin B, but not cyclophilin A, are protected from the development of NASH in a diet and chemical-induced model

Winston T. Stauffer, Asha Z. Goodman, Michael Bobardt, Daren R. Ure, Robert T. Foster, Philippe Gallay

PLoS One. 2024; 19(3): e0298211. Published online 2024 Mar 1. doi: 10.1371/journal.pone.0298211

PMCID:: PMC10906846

Article PDF–3.5M

Select item 106510719.

Relationship of quantitative reverse transcription polymerase chain reaction (RT-PCR) to RNA Sequencing (RNAseq) transcriptome identifies mouse preimplantation embryo reference genes

Allison K Tscherner, Taylor McClatchie, Angus D Macaulay, Jay M Baltz

Biol Reprod. 2023 Nov; 109(5): 601–617. Published online 2023 Sep 5. doi: 10.1093/biolre/ioad107

PMCID:: PMC10651071

Article PDF–2.6M

Select item 1063267710.

Dissecting the role of SWI/SNF component ARID1B in steady-state hematopoiesis

Vikas Madan, Pavithra Shyamsunder, Pushkar Dakle, Teoh Weoi Woon, Lin Han, Zeya Cao, Hazimah Binte Mohd Nordin, Shi Jizhong, Yu Shuizhou, Md Zakir Hossain, H. Phillip Koeffler

Blood Adv. 2023 Nov 14; 7(21): 6553–6566. Published online 2023 Aug 25. doi: 10.1182/bloodadvances.2023009946

PMCID:: PMC10632677

Article PDF–1.1M

Select item 1040428611.

Cardiomyocyte proliferation is suppressed by ARID1A-mediated YAP inhibition during cardiac maturation

Cornelis J. Boogerd, Ilaria Perini, Eirini Kyriakopoulou, Su Ji Han, Phit La, Britt van der Swaan, Jari B. Berkhout, Danielle Versteeg, Jantine Monshouwer-Kloots, Eva van Rooij

Nat Commun. 2023; 14: 4716. Published online 2023 Aug 5. doi: 10.1038/s41467-023-40203-2

PMCID:: PMC10404286

Article PDF–3.4M

Select item 1027677012.

Arid1a regulates bladder urothelium formation and maintenance

Chunming Guo, Yingsheng Zhang, Ruirong Tan, Zonghao Tang, Christa M. Lam, Xing Ye, Zhong Wang, Xue Li

Dev Biol. Author manuscript; available in PMC 2023 Jun 18.

Published in final edited form as: Dev Biol. 2022 May; 485: 61–69. Published online 2022 Mar 10. doi: 10.1016/j.ydbio.2022.02.008

PMCID:: PMC10276770

Article PDF–2.6M

Select item 1009593513.

Differential roles of BAF and PBAF subunits, Arid1b and Arid2, in MLL-AF9 leukemogenesis

Theresa Bluemn, Jesse Schmitz, Yongwei Zheng, Robert Burns, Shikan Zheng, Joshua DeJong, Luke Christiansen, Olivia Arnold, Jesus Izaguirre-Carbonell, Demin Wang, Aniruddha J Deshpande, Nan Zhu

Leukemia. Author manuscript; available in PMC 2023 Apr 12.

Published in final edited form as: Leukemia. 2022 Apr; 36(4): 946–955. Published online 2022 Jan 12. doi: 10.1038/s41375-021-01505-w

PMCID:: PMC10095935

Article PDF–1.8M

Select item 988872514.

Hepatic ribosomal protein S6 (Rps6) insufficiency results in failed bile duct development and loss of hepatocyte viability; a ribosomopathy-like phenotype that is partially p53-dependent

Sarah A. Comerford, Elizabeth A. Hinnant, Yidong Chen, Robert E. Hammer

PLoS Genet. 2023 Jan; 19(1): e1010595. Published online 2023 Jan 19. doi: 10.1371/journal.pgen.1010595

PMCID:: PMC9888725

Article PDF–6.9M

Select item 968224915.

Detailed characterizations of cranial nerve anatomy in E14.5 mouse embryos/fetuses and their use as reference for diagnosing subtle, but potentially lethal malformations in mutants

Lukas F. Reissig, Stefan H. Geyer, Viola Winkler, Ester Preineder, Fabrice Prin, Robert Wilson, Antonella Galli, Catherine Tudor, Jaqueline K. White, Timothy J. Mohun, Wolfgang J. Weninger

Front Cell Dev Biol. 2022; 10: 1006620. Published online 2022 Nov 9. doi: 10.3389/fcell.2022.1006620

PMCID:: PMC9682249

Article PDF–6.5M

Select item 960625316.

Rescue of deficits by Brwd1 copy number restoration in the Ts65Dn mouse model of Down syndrome

Sasha L. Fulton, Wendy Wenderski, Ashley E. Lepack, Andrew L. Eagle, Tomas Fanutza, Ryan M. Bastle, Aarthi Ramakrishnan, Emma C. Hays, Arianna Neal, Jaroslav Bendl, Lorna A. Farrelly, Amni Al-Kachak, Yang Lyu, Bulent Cetin, Jennifer C. Chan, Tina N. Tran, Rachael L. Neve, Randall J. Roper, Kristen J. Brennand, Panos Roussos, John C. Schimenti, Allyson K. Friedman, Li Shen, Robert D. Blitzer, Alfred J. Robison, Gerald R. Crabtree, Ian Maze

Nat Commun. 2022; 13: 6384. Published online 2022 Oct 26. doi: 10.1038/s41467-022-34200-0

PMCID:: PMC9606253

Article PDF–4.0M

Select item 960386017.

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3

Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany

Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527

PMCID:: PMC9603860

Article PDF–3.4M

Select item 948193318.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Article PDF–3.5M

Select item 942011519.

Early postnatal serotonin modulation prevents adult-stage deficits in Arid1b-deficient mice through synaptic transcriptional reprogramming

Hyosang Kim, Doyoun Kim, Yisul Cho, Kyungdeok Kim, Junyeop Daniel Roh, Yangsik Kim, Esther Yang, Seong Soon Kim, Sunjoo Ahn, Hyun Kim, Hyojin Kang, Yongchul Bae, Eunjoon Kim

Nat Commun. 2022; 13: 5051. Published online 2022 Aug 27. doi: 10.1038/s41467-022-32748-5

PMCID:: PMC9420115

Article PDF–10M

Select item 941891620.

m⁶A regulation of cortical and retinal neurogenesis is mediated by the redundant m⁶A readers YTHDFs

Fugui Niu, Pengfei Che, Zhuoxuan Yang, Jian Zhang, Lixin Yang, Mengru Zhuang, Xijun Ou, Sheng-Jian Ji

iScience. 2022 Sep 16; 25(9): 104908. Published online 2022 Aug 11. doi: 10.1016/j.isci.2022.104908

PMCID:: PMC9418916

Article PDF–7.5M

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